MAGUK proteins: structure and role in the tight junction

Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia.

Stevenson, B. R., Siliciano, J. D., Mooseker, M. S., & Goodenough, D. A. (1986) · The Journal of cell biology · doi:10.1083/jcb.103.3.755 · Cited by 1,638

Interaction of Nitric Oxide Synthase with the Postsynaptic Density Protein PSD-95 and α1-Syntrophin Mediated by PDZ Domains

Brenman, J. E., Chao, D. S., Gee, S. H., McGee, A. W., Craven, S. E., Santillano, D. R., Wu, Z., Huang, F., Xia, H., Peters, M. F., et al. (1996) · Cell · doi:10.1016/s0092-8674(00)81053-3 · Cited by 1,596

The Tight Junction Protein ZO-1 Establishes a Link between the Transmembrane Protein Occludin and the Actin Cytoskeleton

Fanning, A. S., Jameson, B. J., Jesaitis, L. A., & Anderson, J. M. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.45.29745 · Cited by 1,432

Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains

Songyang, Z., Fanning, A. S., Fu, C., Xu, J., Marfatia, S. M., Chishti, A. H., Crompton, A., Chan, A. C., Anderson, J. M., & Cantley, L. C. (1997) · Science · doi:10.1126/science.275.5296.73 · Cited by 1,385

The rat brain postsynaptic density fraction contains a homolog of the drosophila discs-large tumor suppressor protein

Cho, K.-O., Hunt, C. A., & Kennedy, M. B. (1992) · Neuron · doi:10.1016/0896-6273(92)90245-9 · Cited by 1,193

Direct Binding of Three Tight Junction-Associated Maguks, Zo-1, Zo-2, and Zo-3, with the Cooh Termini of Claudins

Itoh, M., Furuse, M., Morita, K., Kubota, K., Saitou, M., & Tsukita, S. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.147.6.1351 · Cited by 1,151

Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases

Kim, E., Niethammer, M., Rothschild, A., Nung Jan, Y., & Sheng, M. (1995) · Nature · doi:10.1038/378085a0 · Cited by 1,000

Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions.

Furuse, M., Itoh, M., Hirase, T., Nagafuchi, A., Yonemura, S., Tsukita, S., & Tsukita, S. (1994) · The Journal of cell biology · doi:10.1083/jcb.127.6.1617 · Cited by 962

Modular binding domains in signal transduction proteins

Cohen, G. B., Ren, R., & Baltimore, D. (1995) · Cell · doi:10.1016/0092-8674(95)90406-9 · Cited by 951

The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions

Woods, D. F., & Bryant, P. J. (1991) · Cell · doi:10.1016/0092-8674(81)90009-x · Cited by 903

Vascular Endothelial Growth Factor Induces Rapid Phosphorylation of Tight Junction Proteins Occludin and Zonula Occluden 1

Antonetti, D. A., Barber, A. J., Hollinger, L. A., Wolpert, E. B., & Gardner, T. W. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.33.23463 · Cited by 686

Involvement of ZO-1 in Cadherin-based Cell Adhesion through Its Direct Binding to α Catenin and Actin Filaments

Itoh, M., Nagafuchi, A., Moroi, S., & Tsukita, S. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.138.1.181 · Cited by 677

A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascade

Tsunoda, S., Sierralta, J., Sun, Y., Bodner, R., Suzuki, E., Becker, A., Socolich, M., & Zuker, C. S. (1997) · Nature · doi:10.1038/40805 · Cited by 614

ZO-3, a Novel Member of the MAGUK Protein Family Found at the Tight Junction, Interacts with ZO-1 and Occludin

Haskins, J., Gu, L., Wittchen, E. S., Hibbard, J., & Stevenson, B. R. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.141.1.199 · Cited by 599

Occludin and claudins in tight-junction strands: leading or supporting players?

Tsukita, S., & Furuse, M. (1999) · Trends in Cell Biology · doi:10.1016/s0962-8924(99)01578-0 · Cited by 597

The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy.

Itoh, M., Nagafuchi, A., Yonemura, S., Kitani-Yasuda, T., Tsukita, S., & Tsukita, S. (1993) · The Journal of cell biology · doi:10.1083/jcb.121.3.491 · Cited by 577

Heteromultimerization and NMDA Receptor-Clustering Activity of Chapsyn-110, a Member of the PSD-95 Family of Proteins

Kim, E., Cho, K.-O., Rothschild, A., & Sheng, M. (1996) · Neuron · doi:10.1016/s0896-6273(00)80284-6 · Cited by 539

Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1.

Gumbiner, B., Lowenkopf, T., & Apatira, D. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.8.3460 · Cited by 523

GKAP, a Novel Synaptic Protein That Interacts with the Guanylate Kinase-like Domain of the PSD-95/SAP90 Family of Channel Clustering Molecules

Kim, E., Naisbitt, S., Hsueh, Y.-P., Rao, A., Rothschild, A., Craig, A. M., & Sheng, M. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.136.3.669 · Cited by 516

The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein

Giepmans, B. N. G., & Moolenaar, W. H. (1998) · Current Biology · doi:10.1016/s0960-9822(07)00375-2 · Cited by 516

An Atypical PKC Directly Associates and Colocalizes at the Epithelial Tight Junction with ASIP, a Mammalian Homologue of Caenorhabditis elegans Polarity Protein PAR-3

Izumi, Y., Hirose, T., Tamai, Y., Hirai, S.-I., Nagashima, Y., Fujimoto, T., Tabuse, Y., Kemphues, K. J., & Ohno, S. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.143.1.95 · Cited by 505

Direct Association of the Gap Junction Protein Connexin-43 with ZO-1 in Cardiac Myocytes

Toyofuku, T., Yabuki, M., Otsu, K., Kuzuya, T., Hori, M., & Tada, M. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.21.12725 · Cited by 488

Protein Interactions at the Tight Junction

Wittchen, E. S., Haskins, J., & Stevenson, B. R. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.49.35179 · Cited by 480

Afadin: A Novel Actin Filament–binding Protein with One PDZ Domain Localized at Cadherin-based Cell-to-Cell Adherens Junction

Mandai, K., Nakanishi, H., Satoh, A., Obaishi, H., Wada, M., Nishioka, H., Itoh, M., Mizoguchi, A., Aoki, T., Fujimoto, T., et al. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.139.2.517 · Cited by 476

The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions.

Willott, E., Balda, M. S., Fanning, A. S., Jameson, B., Van Itallie, C., & Anderson, J. M. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.16.7834 · Cited by 468

The tight junction protein ZO-1 and an interacting transcription factor regulate ErbB-2 expression

Balda, M. S. (2000) · The EMBO Journal · doi:10.1093/emboj/19.9.2024 · Cited by 443

Effects of cytochalasin D on occluding junctions of intestinal absorptive cells: further evidence that the cytoskeleton may influence paracellular permeability and junctional charge selectivity.

Madara, J. L., Barenberg, D., & Carlson, S. (1986) · The Journal of cell biology · doi:10.1083/jcb.102.6.2125 · Cited by 438

SAP90, a rat presynaptic protein related to the product of the Drosophila tumor suppressor gene dlg-A.

Kistner, U., Wenzel, B. M., Veh, R. W., Cases-Langhoff, C., Garner, A. M., Appeltauer, U., Voss, B., Gundelfinger, E. D., & Garner, C. C. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)53433-5 · Cited by 414

Assembly of the tight junction: the role of diacylglycerol.

Balda, M. S., Gonzalez-Mariscal, L., Matter, K., Cereijido, M., & Anderson, J. M. (1993) · The Journal of cell biology · doi:10.1083/jcb.123.2.293 · Cited by 374

Characterization of ZO-1, a protein component of the tight junction from mouse liver and Madin-Darby canine kidney cells.

Anderson, J. M., Stevenson, B. R., Jesaitis, L. A., Goodenough, D. A., & Mooseker, M. S. (1988) · The Journal of cell biology · doi:10.1083/jcb.106.4.1141 · Cited by 368

The junction-associated protein, zonula occludens-1, localizes to the nucleus before the maturation and during the remodeling of cell-cell contacts.

Gottardi, C. J., Arpin, M., Fanning, A. S., & Louvard, D. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.20.10779 · Cited by 367

Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2

Hsueh, Y.-P., Wang, T.-F., Yang, F.-C., & Sheng, M. (2000) · Nature · doi:10.1038/35005118 · Cited by 355

Catenins and zonula occludens-1 form a complex during early stages in the assembly of tight junctions.

Rajasekaran, A. K., Hojo, M., Huima, T., & Rodriguez-Boulan, E. (1996) · The Journal of cell biology · doi:10.1083/jcb.132.3.451 · Cited by 339

The Ras Target AF-6 Interacts with ZO-1 and Serves as a Peripheral Component of Tight Junctions in Epithelial Cells

Yamamoto, T., Harada, N., Kano, K., Taya, S.-I., Canaani, E., Matsuura, Y., Mizoguchi, A., Ide, C., & Kaibuchi, K. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.139.3.785 · Cited by 314

Cingulin Contains Globular and Coiled-Coil Domains and Interacts with Zo-1, Zo-2, Zo-3, and Myosin

Cordenonsi, M., D'Atri, F., Hammar, E., Parry, D. A. D., Kendrick-Jones, J., Shore, D., & Citi, S. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.147.7.1569 · Cited by 312

Characterization of ZO-2 as a MAGUK Family Member Associated with Tight as well as Adherens Junctions with a Binding Affinity to Occludin and α Catenin

Itoh, M., Morita, K., & Tsukita, S. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.9.5981 · Cited by 310

Evidence that tyrosine phosphorylation may increase tight junction permeability

Staddon, J. M., Herrenknecht, K., Smales, C., & Rubin, L. L. (1995) · Journal of Cell Science · doi:10.1242/jcs.108.2.609 · Cited by 310

Tight junction formation in cultured epithelial cells (MDCK)

Gonzalez-Mariscal, L., Chávez de Ramírez, B., & Cereijido, M. (1985) · The Journal of Membrane Biology · doi:10.1007/bf01870778 · Cited by 295

Interferon-γ decreases barrier function in T84 cells by reducing ZO-1 levels and disrupting apical actin

Youakim, A., & Ahdieh, M. (1999) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1999.276.5.g1279 · Cited by 286

Assembly and sealing of tight junctions: Possible participation of G-proteins, phospholipase C, protein kinase C and calmodulin

Balda, M. S., González-Mariscal, L., Contreras, R. G., Macias-Silva, M., Torres-Marquez, M. E., Sáinz, J. A. G., & Cereijido, M. (1991) · The Journal of Membrane Biology · doi:10.1007/bf01871420 · Cited by 280

Protein kinase inhibitors prevent junction dissociation induced by low extracellular calcium in MDCK epithelial cells

Citi, S. (1992) · The Journal of cell biology · doi:10.1083/jcb.117.1.169 · Cited by 275

Occludin confers adhesiveness when expressed in fibroblasts

Itallie, C. M. V., & Anderson, J. M. (1997) · Journal of Cell Science · doi:10.1242/jcs.110.9.1113 · Cited by 271

Binding of the Inward Rectifier K+ Channel Kir 2.3 to PSD-95 Is Regulated by Protein Kinase A Phosphorylation

Cohen, N. A., Brenman, J. E., Snyder, S. H., & Bredt, D. S. (1996) · Neuron · doi:10.1016/s0896-6273(00)80207-x · Cited by 265

Regulated assembly of tight junctions by protein kinase C.

Stuart, R. O., & Nigam, S. K. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.13.6072 · Cited by 262

Evidence for PDZ domains in bacteria, yeast, and plants

Ponting, C. P. (1997) · Protein Science · doi:10.1002/pro.5560060225 · Cited by 251

Regulation of the TRP Ca2+ Channel by INAD in Drosophila Photoreceptors

Shieh, B.-H., & Zhu, M.-Y. (1996) · Neuron · doi:10.1016/s0896-6273(00)80122-1 · Cited by 248

A 220-kD undercoat-constitutive protein: its specific localization at cadherin-based cell-cell adhesion sites.

Itoh, M., Yonemura, S., Nagafuchi, A., Tsukita, S., & Tsukita, S. (1991) · The Journal of cell biology · doi:10.1083/jcb.115.5.1449 · Cited by 235

An SH3 binding region in the epithelial Na+ channel (alpha rENaC) mediates its localization at the apical membrane.

Rotin, D., Bar-Sagi, D., O'Brodovich, H., Merilainen, J., Lehto, V. P., Canessa, C. M., Rossier, B. C., & Downey, G. P. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06766.x · Cited by 220

Two classes of tight junctions are revealed by ZO-1 isoforms

Balda, M. S., & Anderson, J. M. (1993) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1993.264.4.c918 · Cited by 195

The Junction-associated Protein AF-6 Interacts and Clusters with Specific Eph Receptor Tyrosine Kinases at Specialized Sites of Cell–Cell Contact in the Brain

Buchert, M., Schneider, S., Meskenaite, V., Adams, M. T., Canaani, E., Baechi, T., Moelling, K., & Hovens, C. M. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.144.2.361 · Cited by 195

Tight Junction Proteins Form Large Complexes and Associate with the Cytoskeleton in an ATP Depletion Model for Reversible Junction Assembly

Tsukamoto, T., & Nigam, S. K. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.26.16133 · Cited by 189

Loss of the Tight Junction MAGUK ZO-1 in Breast Cancer

Hoover, K. B., Liao, S.-Y., & Bryant, P. J. (1998) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)65691-x · Cited by 184

Localization and differential expression of two isoforms of the tight junction protein ZO-1

Willott, E., Balda, M. S., Heintzelman, M., Jameson, B., & Anderson, J. M. (1992) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1992.262.5.c1119 · Cited by 174

SH3 domains and drug design: Ligands, structure, and biological function

Dalgarno, D. C., Botfield, M. C., & Rickles, R. J. (1997) · Biopolymers · doi:10.1002/(sici)1097-0282(1997)43:5<383::aid-bip4>3.0.co;2-r · Cited by 166

Glucocorticoids regulate transendothelial fluid flow resistance and formation of intercellular junctions

Underwood, J. L., Murphy, C. G., Chen, J., Franse-Carman, L., Wood, I., Epstein, D. L., & Alvarado, J. A. (1999) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1999.277.2.c330 · Cited by 164

Detection of the tight junction-associated protein ZO-1 in astrocytes and other nonepithelial cell types

Howarth, A. G., Hughes, M. R., & Stevenson, B. R. (1992) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1992.262.2.c461 · Cited by 161

Tight junction assembly during mouse blastocyst formation is regulated by late expression of ZO-1 α+ isoform

Sheth, B., Fesenko, I., Collins, J. E., Moran, B., Wild, A. E., Anderson, J. M., & Fleming, T. P. (1997) · Development · doi:10.1242/dev.124.10.2027 · Cited by 160

Cortactin Associates with the Cell-Cell Junction Protein ZO-1 in both Drosophila and Mouse

Katsube, T., Takahisa, M., Ueda, R., Hashimoto, N., Kobayashi, M., & Togashi, S. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.45.29672 · Cited by 149

Increased tyrosine phosphorylation causes redistribution of adherens junction and tight junction proteins and perturbs paracellular barrier function in MDCK epithelia

Collares‐Buzato, C. B., Jepson, M. A., Simmons, N. L., & Hirst, B. H. (1998) · European Journal of Cell Biology · doi:10.1016/s0171-9335(98)80020-4 · Cited by 147

Identification of an Intramolecular Interaction between the SH3 and Guanylate Kinase Domains of PSD-95

McGee, A. W., & Bredt, D. S. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.25.17431 · Cited by 144

Epidermal growth factor induces tyrosine phosphorylation and reorganization of the tight junction protein ZO-1 in A431 cells

Van Itallie, C. M., Balda, M. S., & Anderson, J. M. (1995) · Journal of Cell Science · doi:10.1242/jcs.108.4.1735 · Cited by 131

Identification of Isoforms of G Proteins and PKC that Colocalize with Tight Junctions

Dodane, V., & Kachar, B. (1996) · The Journal of Membrane Biology · doi:10.1007/s002329900020 · Cited by 127

CIPP, a Novel Multivalent PDZ Domain Protein, Selectively Interacts with Kir4.0 Family Members, NMDA Receptor Subunits, Neurexins, and Neuroligins

Kurschner, C., Mermelstein, P. G., Holden, W. T., & Surmeier, D. J. (1998) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.1998.0679 · Cited by 122

Occluding Junctions in MDCK Cells: Modulation of Transepithelial Permeability by the Cytoskeleton

Meza, I., Sabanero, M., Stefani, E., & Cereijido, M. (1982) · Journal of Cellular Biochemistry · doi:10.1002/jcb.1982.240180403 · Cited by 114

Direct binding between two PDZ domain proteins Canoe and ZO-1 and their roles in regulation of the Jun N-terminal kinase pathway in Drosophila morphogenesis

Takahashi, K., Matsuo, T., Katsube, T., Ueda, R., & Yamamoto, D. (1998) · Mechanisms of Development · doi:10.1016/s0925-4773(98)00151-8 · Cited by 107

Phosphorylation of the tight-junction protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance

Stevenson, B. R., Anderson, J. M., Braun, I. D., & Mooseker, M. S. (1989) · Biochemical Journal · doi:10.1042/bj2630597 · Cited by 106

The Tight Junction Protein ZO-2 Contains Three PDZ (PSD-95Discs-LargeZO-1) Domains and an Alternatively Spliced Region

Beatch, M. D., Jesaitis, L. A., Gallin, W. J., Goodenough, D. A., & Stevenson, B. R. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.42.25723 · Cited by 104

The SH3 domain of the tight junction protein ZO‐1 binds to a serine protein kinase that phosphorylates a region C‐terminal to this domain

Balda, M. S., Anderson, J. M., & Matter, K. (1996) · FEBS Letters · doi:10.1016/s0014-5793(96)01352-x · Cited by 103

BEGAIN (Brain-enriched Guanylate Kinase-associated Protein), a Novel Neuronal PSD-95/SAP90-binding Protein

Deguchi, M., Hata, Y., Takeuchi, M., Ide, N., Hirao, K., Yao, I., Irie, M., Toyoda, A., & Takai, Y. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.41.26269 · Cited by 97

The making of a tight junction

Cereijido, M., González‐Mariscal, L., Contreras, R. G., Gallardo, J. M., Garcı́a-Villegas, R., & Valdés, J. (1993) · Journal of Cell Science · doi:10.1242/jcs.1993.supplement_17.18 · Cited by 91

Protein Kinase C-α Activity Modulates Transepithelial Permeability and Cell Junctions in the LLC-PK1 Epithelial Cell Line

Rosson, D., O’Brien, T. G., Kampherstein, J. A., Szállási, Z., Bögi, K., Blumberg, P. M., & Mullin, J. M. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.23.14950 · Cited by 89

Interaction of NE-dlg/SAP102, a Neuronal and Endocrine Tissue-specific Membrane-associated Guanylate Kinase Protein, with Calmodulin and PSD-95/SAP90

Masuko, N., Makino, K., Kuwahara, H., Fukunaga, K., Sudo, T., Araki, N., Yamamoto, H., Yamada, Y., Miyamoto, E., & Saya, H. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.9.5782 · Cited by 88

Tight junctions and apical/basolateral polarity

Cereijido, M., Ponce, A., & González‐Mariscal, L. (1989) · The Journal of Membrane Biology · doi:10.1007/bf01870987 · Cited by 86

Cytoskeletal involvement in the modulation of cell-cell junctions by the protein kinase inhibitor H-7

Citi, S., Volberg, T., Bershadsky, A. D., Denisenko, N., & Geiger, B. (1994) · Journal of Cell Science · doi:10.1242/jcs.107.3.683 · Cited by 78

The Drosophila tamou gene, a component of the activating pathway of extramacrochaetae expression, encodes a protein homologous to mammalian cell-cell junction-associated protein ZO-1.Preprint

Takahisa, M., Togashi, S., Suzuki, T., Kobayashi, M., Murayama, A., Kondo, K., Miyake, T., & Ueda, R. (1996) · Genes & Development · doi:10.1101/gad.10.14.1783 · Cited by 75

Overexpression of protein kinase C-δ increases tight junction permeability in LLC-PK1epithelia

Mullin, J. M., Kampherstein, J. A., Laughlin, K. V., Clarkin, C. E. K., Miller, R., Szállási, Z., Kachar, B., Soler, A. P., & Rosson, D. (1998) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1998.275.2.c544 · Cited by 73

Nucleotide bindind by the synapse associated protein SAP90

Kistner, U., Garner, C. C., & Linial, M. (1995) · FEBS Letters · doi:10.1016/0014-5793(95)00030-d · Cited by 72

Connexin-Occludin Chimeras Containing the Zo-Binding Domain of Occludin Localize at Mdck Tight Junctions and Nrk Cell Contacts

Mitic, L. L., Schneeberger, E. E., Fanning, A. S., & Anderson, J. M. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.146.3.683 · Cited by 68

In VivoInteraction of AF-6 with Activated Ras and ZO-1

Yamamoto, T. G., Harada, N., Kawano, Y., Taya, S., & Kaibuchi, K. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.0731 · Cited by 67

Tight junction protein zo-2 is differentially expressed in normal pancreatic ducts compared to human pancreatic adenocarcinoma

Chlenski, A., Ketels, K. V., Tsao, M., Talamonti, M., Anderson, M., Oyasu, R., & Scarpelli, D. G. (1999) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19990702)82:1<137::aid-ijc23>3.0.co;2-f · Cited by 61

Effects of Tyrosine Phosphorylation on Tight Junctions in Temperature-Sensitive v-src-transfected MDCK Cells.

Takeda, H., & Tsukita, S. (1995) · Cell Structure and Function · doi:10.1247/csf.20.387 · Cited by 55

Different effects of protein kinase inhibitors on the localization of junctional proteins at cell-cell contact sites

Denisenko, N., Burighel, P., & Citi, S. (1994) · Journal of Cell Science · doi:10.1242/jcs.107.4.969 · Cited by 50

Molecular Characterization of the Tight Junction Protein ZO-1 in MDCK Cells

González‐Mariscal, L., Islas, S., Contreras, R. G., García-Villegas, R., Betanzos, A., Vega, J., Díaz-Quiñónez, J. A., Martín‐Orozco, N., Ortiz-Navarrete, V. F., Cereijido, M., et al. (1999) · Experimental Cell Research · doi:10.1006/excr.1999.4392 · Cited by 49

Molecular environment of ZO‐1 in epithelial and non‐epithelial cells

Howarth, A. G., & Stevenson, B. R. (1995) · Cell Motility and the Cytoskeleton · doi:10.1002/cm.970310408 · Cited by 48

zo-2 gene alternative promoters in normal and neoplastic human pancreatic duct cells

Chlenski, A., Ketels, K. V., Engeriser, J. L., Talamonti, M. S., Tsao, M., Koutnikova, H., Oyasu, R., & Scarpelli, D. G. (1999) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19991029)83:3<349::aid-ijc10>3.0.co;2-c · Cited by 32

Activation of channel activity of the NMDA receptor‐PSD‐95 complex by guanylate kinase‐associated protein (GKAP)

Yamada, Y., Chochi, Y., Ko, J., Sobue, K., & Inui, M. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)01171-0 · Cited by 25

Protein-Binding Domains of the Tight Junction Protein, ZO-2, Are Highly Conserved between Avian and Mammalian Species

Collins, J. R., & Rizzolo, L. J. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.9710 · Cited by 15

The blood-brain barrier/neurovascular unit in health and disease

Hawkins, B. T., & Davis, T. P. (2005) · Pharmacological Reviews · doi:10.1124/pr.57.2.4 · Cited by 2,661

Blood–brain Barrier: Structural Components and Function Under Physiologic and Pathologic Conditions

Persidsky, Y., Ramirez, S. H., Haorah, J., & Kanmogne, G. D. (2006) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-006-9025-3 · Cited by 922

Crosstalk of tight junction components with signaling pathways

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