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Destabilization of the RB Tumor Suppressor Protein and Stabilization of p53 Contribute to HPV Type 16 E7-Induced Apoptosis
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“high-risk HPV-16 E7 can destabilize pRB [127,128] through proteasomal degradation by interacting with the cullin 2 ubiquitin ligase complex [129]”
From The Not-So-Good, the Bad and the Ugly: HPV E5, E6 and E7 Oncoproteins in the Orchestration of Carcinogenesis (2021) · cites this paper as [128]
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Cited by
Thomas, D. M., Carty, S. A., Piscopo, D. M., Lee, J.-S., Wang, W.-F., Forrester, W. C., & Hinds, P. W. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00327-6 · Cited by 361
White, E. A., Sowa, M. E., Tan, M. J. A., Jeudy, S., Hayes, S. D., Santha, S., Münger, K., Harper, J. W., & Howley, P. M. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1116776109 · Cited by 198
Self-citationHarnessing the Ubiquitination Machinery to Target the Degradation of Specific Cellular Proteins
Zhou, P., Bogacki, R., McReynolds, L., & Howley, P. M. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)00074-5 · Cited by 164
Basukala, O., & Banks, L. (2021) · Viruses · doi:10.3390/v13101892 · Cited by 137
E3 ubiquitin ligases and human papillomavirus-induced carcinogenesis
Lou, Z., & Wang, S. (2014) · Journal of International Medical Research · doi:10.1177/0300060513506655 · Cited by 22
Metadata
- Authors
- Jones, D. L., Thompson, D. A., & Münger, K.
- Venue
- Virology
- Publisher
- Elsevier BV
- Published
- 1997-12
- Volume
- 239
- Issue
- 1
- Pages
- 97-107
- ISSN
- 0042-6822
- Cited by
- 231
- References
- 1
- Language
- en
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- Jones, D. L., Thompson, D. A., & Münger, K. (1997). Destabilization of the RB Tumor Suppressor Protein and Stabilization of p53 Contribute to HPV Type 16 E7-Induced Apoptosis. Virology. https://doi.org/10.1006/viro.1997.8851