Cited by 160Neurobiology and Insect Physiology ResearchSteroid Chemistry and BiochemistryEstrogen and related hormone effects

The DOI matches its Crossref record.

Ecdysone: Structures and Functions

Guy J. Smagghe·2009·Springer eBooks

DOI 10.1007/978-1-4020-9112-4

Open this paper in CoChat — free account

Integrity signals

Registry

Crossref · 10.1007/978-1-4020-9112-4

Cites

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Sorted by citations

RNA interference in Lepidoptera: An overview of successful and unsuccessful studies and implications for experimental design
Terenius, O., Papanicolaou, A., Garbutt, J. S., Eleftherianos, I., Huvenne, H., Kanginakudru, S., Albrechtsen, M., An, C., Aymeric, J. L., Barthel, A., et al. (2010) · Journal of Insect Physiology · doi:10.1016/j.jinsphys.2010.11.006 · Cited by 877
Self-citation
Phytosterols and their derivatives: Structural diversity, distribution, metabolism, analysis, and health-promoting uses
Moreau, R. A., Nyström, L., Whitaker, B. D., Winkler‐Moser, J. K., Baer, D. J., Gebauer, S. K., & Hicks, K. B. (2018) · Progress in Lipid Research · doi:10.1016/j.plipres.2018.04.001 · Cited by 451
Pseudocereal grains: Nutritional value, health benefits and current applications for the development of gluten-free foods
Martínez‐Villaluenga, C., Peñas, E., & Hernández‐Ledesma, B. (2020) · Food and Chemical Toxicology · doi:10.1016/j.fct.2020.111178 · Cited by 341
Diversity and evolution of the P450 family in arthropods
Dermauw, W., Leeuwen, T. V., & Feyereisen, R. (2020) · Insect Biochemistry and Molecular Biology · doi:10.1016/j.ibmb.2020.103490 · Cited by 261
Ecdysteroid metabolism in crustaceans
Mykles, D. L. (2010) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2010.09.001 · Cited by 228
Ecdysteroid Chemistry and Biochemistry
Lafont, R., Dauphin‐Villemant, C., Warren, J. T., & Rees, H. H. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-384749-2.10004-4 · Cited by 176
Ecdysone signaling in adult Drosophila melanogaster
Schwedes, C. C., & Carney, G. E. (2012) · Journal of Insect Physiology · doi:10.1016/j.jinsphys.2012.01.013 · Cited by 168
Developmental Checkpoints and Feedback Circuits Time Insect Maturation
Rewitz, K., Yamanaka, N., & O’Connor, M. B. (2013) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/b978-0-12-385979-2.00001-0 · Cited by 143
Insect Nuclear Receptors
Fahrbach, S. E., Smagghe, G. J., & Velarde, R. A. (2011) · Annual Review of Entomology · doi:10.1146/annurev-ento-120710-100607 · Cited by 150
Self-citation
Transcriptomic variation of hepatopancreas reveals the energy metabolism and biological processes associated with molting in Chinese mitten crab, Eriocheir sinensis
Huang, S., Wang, J., Yue, W., Chen, J., Gaughan, S., Lu, W., Lu, G., & Wang, C. (2015) · Scientific Reports · doi:10.1038/srep14015 · Cited by 134
Ecdysteroid hormone action
Spindler, K., Hönl, C. E., Tremmel, C., Braun, S., Ruff, H., & Spindler‐Barth, M. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-009-0112-5 · Cited by 129
Regulation of the cholesterol biosynthetic pathway and its integration with fatty acid biosynthesis in the oleaginous microalga Nannochloropsis oceanica
Lu, Y., Zhou, W., Wei, L., Li, J., Jia, J., Li, F., Smith, S. M., & Xu, J. (2014) · Biotechnology for Biofuels · doi:10.1186/1754-6834-7-81 · Cited by 103
“molting hormones [4], mammalian steroid hormones [5], and plant brassinosteroid (BR) hormones [6].”
Background
An Overview of Insect Growth Disruptors; Applied Aspects
Pener, M. P., & Dhadialla, T. S. (2012) · Advances in insect physiology · doi:10.1016/b978-0-12-391500-9.00001-2 · Cited by 101
Ecdysteroids from Chenopodium quinoa Willd., an Ancient Andean Crop of High Nutritional Value
Kumpun, S., Maria, A., Crouzet, S., Evrard-Todeschi, N., Girault, J.-P., & Lafont, R. (2011) · Food Chemistry · doi:10.1016/j.foodchem.2010.10.039 · Cited by 99
Botany, Nutritional Value, Phytochemical Composition and Biological Activities of Quinoa
Hussain, M. I., Farooq, M., Syed, Q. A., Ishaq, A., Al-Ghamdi, A. A., & Hatamleh, A. A. (2021) · Plants · doi:10.3390/plants10112258 · Cited by 96
Nutrient Signaling and Developmental Timing of Maturation
Danielsen, E. T., Moeller, M. E., & Rewitz, K. (2013) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/b978-0-12-396968-2.00002-6 · Cited by 89
Roles of ecdysteroids for progression of reproductive cycle in the fresh water crustacean Daphnia magna
Sumiya, E., Ogino, Y., Miyakawa, H., et al. (2014) · Frontiers in Zoology · doi:10.1186/s12983-014-0060-2 · Cited by 89
De novo Transcriptome Analysis of Portunus trituberculatus Ovary and Testis by RNA-Seq: Identification of Genes Involved in Gonadal Development
Meng, X., Liu, P., Jia, F.-L., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0128659 · Cited by 86
Comprehensive survey of developmental genes in the pea aphid, Acyrthosiphon pisum : frequent lineage‐specific duplications and losses of developmental genes
Shigenobu, S., Bickel, R. D., Brisson, J. A., Butts, T., Chang, C., Christiaens, O., Davis, G. K., Duncan, E. J., Ferrier, D. E. K., Iga, M., et al. (2010) · Insect Molecular Biology · doi:10.1111/j.1365-2583.2009.00944.x · Cited by 85
“Many nuclear receptors are transcriptionally regulated by the steroid hormone ecdysone and play important roles in diverse developmental processes of insects such as molting (Smagghe, 2009).”
BackgroundSelf-citation
Photoautotrophic propagation of Brazilian ginseng [Pfaffia glomerata (Spreng.) Pedersen]
Iarema, L., da Cruz, A. C. F., Saldanha, C. W., Dias, L. L. C., Vieira, R. F., de Oliveira, E. J., & Otoni, W. C. (2012) · Plant Cell Tissue and Organ Culture (PCTOC) · doi:10.1007/s11240-012-0145-6 · Cited by 82
The UV filter benzophenone 3 (BP-3) activates hormonal genes mimicking the action of ecdysone and alters embryo development in the insect Chironomus riparius (Diptera)
Ozáez, I., Martínez‐Guitarte, J., & Morcillo, G. (2014) · Environmental Pollution · doi:10.1016/j.envpol.2014.04.038 · Cited by 80
“Ecdysteroid hormones exert their function at the genomic level and regulate growth, development and reproduction in arthropods (Smagghe, 2009).”
Background
The Ecdysteroid Receptor
Henrich, V. C. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-384749-2.10005-6 · Cited by 83
Diversity of Secondary Metabolites in the Genus Silene L. (Caryophyllaceae)—Structures, Distribution, and Biological Properties
Mamadalieva, N. Z., Lafont, R., & Wink, M. (2014) · Diversity · doi:10.3390/d6030415 · Cited by 84
The BPA-substitute bisphenol S alters the transcription of genes related to endocrine, stress response and biotransformation pathways in the aquatic midge Chironomus riparius (Diptera, Chironomidae)
Herrero, Ó., Aquilino, M., Sánchez‐Argüello, P., & Planelló, R. (2018) · PLoS ONE · doi:10.1371/journal.pone.0193387 · Cited by 75
Nitric Oxide Synthase Regulates Growth Coordination During Drosophila melanogaster Imaginal Disc Regeneration
Jaszczak, J. S., Wolpe, J. B., Dao, A. Q., et al. (2015) · Genetics · doi:10.1534/genetics.115.178053 · Cited by 65
Exposure to heavy metal-contaminated sediments disrupts gene expression, lipid profile, and life history traits in the midge Chironomus riparius
Arambourou, H., Llorente, L., Moreno-Ocio, I., Herrero, Ó., Barata, C., Fuertes, I., Delorme, N., Méndez-Fernández, L., & Planelló, R. (2019) · Water Research · doi:10.1016/j.watres.2019.115165 · Cited by 62
Transcriptome Analysis and Differential Gene Expression on the Testis of Orange Mud Crab, Scylla olivacea, during Sexual Maturation
Waiho, K., Fazhan, H., Shahreza, M. S., Moh, J. H. Z., Noorbaiduri, S., Wong, L. L., Sinnasamy, S., & Ikhwanuddin, M. (2017) · PLoS ONE · doi:10.1371/journal.pone.0171095 · Cited by 53
Neuropeptidergic regulation of reproduction in insects
Wielendaele, P. V., Badisco, L., & Broeck, J. V. (2013) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2013.02.005 · Cited by 51
Phytoestrogens, phytosteroids and saponins in vegetables: Biosynthesis, functions, health effects and practical applications
Gioia, F. D., & Petropoulos, S. A. (2019) · Advances in food and nutrition research · doi:10.1016/bs.afnr.2019.02.004 · Cited by 52
Ecdysteroids
Lafont, R., Balducci, C., & Dinan, L. (2021) · Encyclopedia · doi:10.3390/encyclopedia1040096 · Cited by 49
Phytoecdysteroids: Distribution, Structural Diversity, Biosynthesis, Activity, and Crosstalk with Phytohormones
Arif, Y., Singh, P., Bajguz, A., & Hayat, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158664 · Cited by 50
Ecdysteroids in Plants and their Pharmacological Effects in Vertebrates and Humans
(2015) · Studies in Natural Products Chemistry · doi:10.1016/b978-0-444-63473-3.00005-8 · Cited by 48
The Mechanistic, Genetic, and Evolutionary Basis of Worker Sterility in the Social Hymenoptera
Ronai, I., Vergoz, V., & Oldroyd, B. P. (2016) · Advances in the study of behavior · doi:10.1016/bs.asb.2016.03.002 · Cited by 49
Promoting effects of lipophilic pollutants on the reproductive toxicity of proteinophilic pollutants to Daphnia magna under chronic exposure
Zhang, J., Zhang, Y., Xia, X., Ma, C., Zhang, Q., Yao, L., Zhang, Q., Wen, W., & Yang, Z. (2025) · Environmental Pollution · doi:10.1016/j.envpol.2025.126013 · Cited by 48
Neuropeptide signaling mechanisms in crustacean and insect molting glands
Covi, J. A., Chang, E. S., & Mykles, D. L. (2011) · Invertebrate Reproduction & Development · doi:10.1080/07924259.2011.588009 · Cited by 46
Involvement of the G-Protein-Coupled Dopamine/Ecdysteroid Receptor DopEcR in the Behavioral Response to Sex Pheromone in an Insect
Abrieux, A., Debernard, S., Maria, A., Gaertner, C., Anton, S., Gadenne, C., & Duportets, L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0072785 · Cited by 47
Elucidating the molecular mechanisms of essential oils' insecticidal action using a novel cheminformatics protocol
Corrêa, E. J. A., Carvalho, F. C., Oliveira, J. A. D. C., Bertolucci, S. K. V., Scotti, M. T., da Silveira, C. H., Guedes, F. C., Melo, J. O. F., de Melo-Minardi, R. C., & de Lima, L. H. F. (2023) · Scientific Reports · doi:10.1038/s41598-023-29981-3 · Cited by 52
Endocrine interactions between plants and animals: Implications of exogenous hormone sources for the evolution of hormone signaling
Miller, A. E. M., & Heyland, A. (2009) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2009.09.016 · Cited by 42
Hsc70 binds to ultraspiracle resulting in the upregulation of 20-hydroxyecdsone-responsive genes in Helicoverpa armigera
Zheng, W., Yang, D., Wang, J., Song, Q., Gilbert, L. I., & Zhao, X. (2009) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2009.10.018 · Cited by 42
Identification of potential markers and sensitive tissues for low or high salinity stress in an intertidal mud crab (Macrophthalmus japonicus)
Nikapitiya, C., Kim, W.-S., Park, K., et al. (2014) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2014.09.018 · Cited by 40
Impact of a perfluorinated organic compound PFOS on the terrestrial pollinator Bombus terrestris (Insecta, Hymenoptera)
Mommaerts, V., Hagenaars, A., Meyer, J., Coen, W. D., Swevers, L., Mosallanejad, H., & Smagghe, G. J. (2011) · Ecotoxicology · doi:10.1007/s10646-011-0596-2 · Cited by 39
Self-citation
Steroidogenesis in plants – Biosynthesis and conversions of progesterone and other pregnane derivatives
Lindemann, P. (2015) · Steroids · doi:10.1016/j.steroids.2015.08.007 · Cited by 40
Host nutritional status mediates degree of parasitoid virulence
Fanny Maure, A., Frédéric Thomas, A., Doyon, J., & Jacques Brodeur, B. (2015) · Oikos · doi:10.1111/oik.02944 · Cited by 35
Retinoid metabolism in invertebrates: When evolution meets endocrine disruption
André, A., Ruivo, R., Gesto, M., Castro, L. F. C., & Santos, M. M. (2014) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2014.08.005 · Cited by 35
Evidence that Polysphincta-group wasps (Hymenoptera: Ichneumonidae) use ecdysteroids to manipulate the web-construction behaviour of their spider hosts
Eberhard, W. G., & Gonzaga, M. O. (2019) · Biological Journal of the Linnean Society · doi:10.1093/biolinnean/blz044 · Cited by 36
Marine natural products from zoantharians: bioactivity, biosynthesis, systematics, and ecological roles
Guillén, P. O., Jaramillo, K. B., Genta‐Jouve, G., et al. (2019) · Natural Product Reports · doi:10.1039/c9np00043g · Cited by 36
Methyl farnesoate synthesis in the lobster mandibular organ: The roles of HMG-CoA reductase and farnesoic acid O-methyltransferase
Li, S., Friesen, J. A., Holford, K. C., & Borst, D. W. (2009) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2009.09.016 · Cited by 34
Cholesterol internalization and metabolism in insect prothoracic gland, a steroidogenic organ, via lipoproteins
Igarashi, F., Ogihara, M. H., Iga, M., & Kataoka, H. (2018) · Steroids · doi:10.1016/j.steroids.2018.01.012 · Cited by 33
Isoprenoid Production via Plant Cell Cultures: Biosynthesis, Accumulation and Scaling-Up to Bioreactors
Nosov, A. M., Popova, E., & Kochkin, D. V. (2014) · Springer eBooks · doi:10.1007/978-94-017-9223-3_23 · Cited by 33
Changes in Energy Metabolism Trigger Pupal Diapause Transition of Bactrocera minax After 20-Hydroxyecdysone Application
Dong, Y., Chen, Z.-Z., Clarke, A. R., & Niu, C.-Y. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.01288 · Cited by 32
“Steroid hormones are thought traditionally to modulate the transcription of mRNA and subsequent protein biosynthesis in a classic model of genomic actions (McEwen, 1992, 1994), while evidence for non-genomic effects has shown that steroids can operate independently or simultaneously with genomic actions (Wehling, 1997…”
BackgroundInfluential
Comprehensive analysis of metabolomics and transcriptomics provides insights into growth difference of juvenile Eriocheir sinensis during the molting cycle
Wang, J., Hou, X., Chen, X., Zhang, K., Wang, J., & Wang, C.-H. (2021) · Aquaculture · doi:10.1016/j.aquaculture.2021.736661 · Cited by 31
Ecdysteroid signalling in insects—From biosynthesis to gene expression regulation
Yamanaka, N. (2021) · Advances in insect physiology · doi:10.1016/bs.aiip.2021.03.002 · Cited by 33
Ecdysterone and Turkesterone—Compounds with Prominent Potential in Sport and Healthy Nutrition
Todorova, V., Ivanova, S., Chakarov, D., Kraev, K., & Ivanov, K. (2024) · Nutrients · doi:10.3390/nu16091382 · Cited by 31
Synthesis, binding and bioactivity of γ-methylene γ-lactam ecdysone receptor ligands: Advantages of QSAR models for flexible receptors
Birru, W. A., Fernley, R. T., Graham, L. D., Grusovin, J., Hill, R. J., Hofmann, A., Howell, L., James, P., Jarvis, K. E., Johnson, W. M. P., et al. (2010) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2010.06.020 · Cited by 31
Commentary: Assessing the endocrine disrupting effects of chemicals on invertebrates in the European Union
Crane, M., Dungey, S., Lillicrap, A. D., Thompson, H., Weltje, L., Wheeler, J. R., & Lagadic, L. (2022) · Environmental Sciences Europe · doi:10.1186/s12302-022-00613-3 · Cited by 34
Structure and function of the alternatively spliced isoforms of the ecdysone receptor gene in the Chinese mitten crab, Eriocheir sinensis
Chen, X., Wang, J., Yue, W., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-13474-1 · Cited by 30
Blooming cyanobacteria alter water flea reproduction via exudates of estrogen analogues
Xu, R., Jiang, Y., MacIsaac, H. J., Chen, L., Li, J., Xu, J., Wang, T., Zi, Y., & Chang, X. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.133909 · Cited by 30
Silencing Br-C impairs larval development and chitin synthesis in Lymantria dispar larvae
Ding, N., Wang, Z., Geng, N., Zou, H., Zhang, G., Cao, C., Li, X., & Zou, C. (2020) · Journal of Insect Physiology · doi:10.1016/j.jinsphys.2020.104041 · Cited by 30
LC/MS/MS identification of 20-hydroxyecdysone in a scorpion (Liocheles australasiae) and its binding affinity to in vitro-translated molting hormone receptors
Miyashita, M., Matsushita, K., Nakamura, S., Akahane, S., Nakagawa, Y., & Miyagawa, H. (2011) · Insect Biochemistry and Molecular Biology · doi:10.1016/j.ibmb.2011.09.002 · Cited by 30
Characterization of ecdysteroids in Drosophila melanogaster by enzyme immunoassay and nano-liquid chromatography–tandem mass spectrometry
Blais, C., Blasco, T., Maria, A., Dauphin‐Villemant, C., & Lafont, R. (2010) · Journal of Chromatography B · doi:10.1016/j.jchromb.2010.02.018 · Cited by 30
24-Epibrassinolide and 20-hydroxyecdysone affect photosynthesis differently in maize and spinach
Rothová, O., Hola, D., Kočová, M., Tůmová, L., Hnilička, F., Hniličková, H., Kamlar, M., & Macek, T. (2014) · Steroids · doi:10.1016/j.steroids.2014.04.006 · Cited by 29
Identification and expression of the ecdysone receptor in the harpacticoid copepod, Amphiascus tenuiremis, in response to fipronil
Gaertner, K. E., Chandler, G. T., Quattro, J. M., et al. (2011) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2011.09.008 · Cited by 28
Functional characterization of CYP71D443, a cytochrome P450 catalyzing C-22 hydroxylation in the 20-hydroxyecdysone biosynthesis of Ajuga hairy roots
Tsukagoshi, Y., Ohyama, K., Seki, H., Akashi, T., Muranaka, T., Suzuki, H., & Fujimoto, Y. (2016) · Phytochemistry · doi:10.1016/j.phytochem.2016.03.010 · Cited by 27
Cloning and functional analysis of the ecdysteroid receptor complex in the opossum shrimp Neomysis integer (Leach, 1814)
Wilde, R. D., Swevers, L., Soin, T., Christiaens, O., Rougé, P., Cooreman, K., Janssen, C., & Smagghe, G. J. (2013) · Aquatic Toxicology · doi:10.1016/j.aquatox.2012.12.011 · Cited by 31
Self-citation
NR3E receptors in cnidarians: A new family of steroid receptor relatives extends the possible mechanisms for ligand binding
Khalturin, K., Billas, I. M. L., Chebaro, Y., Reitzel, A. M., Tarrant, A. M., Laudet, V., & Markov, G. V. (2018) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2018.06.014 · Cited by 25
20-Hydroxyecdysone Attenuates TGF-Β1-Induced Renal Cellular Fibrosis in Proximal Tubule Cells
Hung, T.-J., Chen, W.-M., Liu, S.-F., Liao, T.-N., Lee, T.-C., Chuang, L.-Y., Guh, J.-Y., Hung, C.-Y., Hung, Y.-J., Chen, P.-Y., et al. (2012) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2012.06.014 · Cited by 25
Developmental endpoints of chronic exposure to suspected endocrine-disrupting chemicals on benthic and hyporheic freshwater copepods
Marzio, W. D. D., Castaldo, D., Lorenzo, T. D., Cioccio, A. D., Sáenz, M. E., & Galassi, D. M. P. (2013) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2013.06.029 · Cited by 25
An ortholog of the ecdysone receptor protein (EcR) from the parasitic nematode Haemonchus contortus
Graham, L. D., Kotze, A. C., Fernley, R. T., & Hill, R. J. (2010) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2010.03.003 · Cited by 25
Phytoecdysteroids from the rhizomes of Brainea insignis
Wu, P., Xie, H., Tao, W., Miao, S., & Wei, X. (2010) · Phytochemistry · doi:10.1016/j.phytochem.2010.03.002 · Cited by 24
Changes in seasonal expression patterns of ecdysone receptor, retinoid X receptor and an A-type allatostatin in the copepod, Calanus finmarchicus, in a sea loch environment: An investigation of possible mediators of diapause
Clark, K. A. J., Brierley, A. S., Pond, D. W., & Smith, V. J. (2013) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2013.04.002 · Cited by 22
Crucial Role of Juvenile Hormone Receptor Components Methoprene-Tolerant and Taiman in Sexual Maturation of Adult Male Desert Locusts
Holtof, M., Gijbels, M., Lommel, J. V., Dekempeneer, E., Nicolaï, B. M., Broeck, J. V., & Marchal, E. (2021) · Biomolecules · doi:10.3390/biom11020244 · Cited by 26
Ecdysone receptor homologs from mollusks, leeches and a polychaete worm
Laguerre, M. S., & Veenstra, J. A. (2010) · FEBS Letters · doi:10.1016/j.febslet.2010.10.004 · Cited by 23
Protective role of 20-OH ecdysone on lipid profile and tissue fatty acid changes in streptozotocin induced diabetic rats
Naresh Kumar, R., Sundaram, R., Shanthi, P., & Sachdanandam, P. (2013) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2012.10.016 · Cited by 21
Significant fluctuations in ecdysteroid receptor gene (EcR) expression in relation to seasons of molt and reproduction in the grapsid crab, Metopograpsus messor (Brachyura: Decapoda)
Shyamal, S., Anilkumar, G., Bhaskaran, R., et al. (2014) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2014.11.006 · Cited by 21
Circadian regulation of hemolymph and ovarian ecdysteroids during egg development in the insect Rhodnius prolixus (Hemiptera)
Cardinal-Aucoin, M., Rapp, N. P., & Steel, C. G. H. (2013) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2013.08.003 · Cited by 21
Design and studies of novel polyoxysterol-based porphyrin conjugates
Zhylitskaya, H. A., Zhabinskii, V. N., Litvinovskaya, R. P., et al. (2012) · Steroids · doi:10.1016/j.steroids.2012.07.005 · Cited by 20
“Brassinosteroids (BS, hormones of plants) [21] and ecdysteroids (ES, hormones of arthropods ) [22] belong to the most remarkable members of the series.”
Sustainable Production of Ajuga Bioactive Metabolites Using Cell Culture Technologies: A Review
Popova, E., Титова, М. В., Тыныкулов, М., Zakirova, R. P., Куличенко, И. Е., Prudnikova, O. N., & Nosov, A. M. (2023) · Nutrients · doi:10.3390/nu15051246 · Cited by 23
Interactions of the crustacean nuclear receptors HR3 and E75 in the regulation of gene transcription
Hannas, B. R., Wang, Y. H., Baldwin, W. S., et al. (2010) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2010.03.025 · Cited by 20
“Much is known about the structure, function, and interplay of these signaling components in insects (Smagghe, 2009).”
Background
Centrifugal partition chromatography in the isolation of minor ecdysteroids from Cyanotis arachnoidea
Issaadi, H. M., Tsai, Y.-C., Chang, F.-R., & Hunyadi, A. (2017) · Journal of Chromatography B · doi:10.1016/j.jchromb.2017.03.043 · Cited by 19
Identification and characterisation of the ecdysone biosynthetic genes neverland, disembodied and shade in the salmon louse Lepeophtheirus salmonis (Copepoda, Caligidae)
Sandlund, L., Kongshaug, H., Horsberg, T. E., Male, R., Nilsen, F., & Dalvin, S. T. (2018) · PLoS ONE · doi:10.1371/journal.pone.0191995 · Cited by 19
Intrinsic disorder of Drosophila melanogaster hormone receptor 38 N‐terminal domain
Dziedzic‐Letka, A., Rymarczyk, G., Kapłon, T. M., Górecki, A., Szamborska‐Gbur, A., Wojtas, M., Dobryszycki, P., & Ożyhar, A. (2010) · Proteins Structure Function and Bioinformatics · doi:10.1002/prot.22887 · Cited by 19
Structure–Activity Relationships of Ecdysteroids and Non-Steroidal Ecdysone Agonists
Dinan, L. N., Nakagawa, Y., & Hormann, R. E. (2012) · Advances in insect physiology · doi:10.1016/b978-0-12-391500-9.00003-6 · Cited by 20
Structure and Function of Ecdysone Receptors—Interactions with Ecdysteroids and Synthetic Agonists
Hill, R. J., Graham, L. D., Turner, K. A., Howell, L., Tohidi‐Esfahani, D., Fernley, R. T., Grusovin, J., Ren, B., Pilling, P. A., Lu, L., et al. (2012) · Advances in insect physiology · doi:10.1016/b978-0-12-391500-9.00004-8 · Cited by 18
Environmental causes and transgenerational consequences of ecdysteroid hormone provisioning in Acheta domesticus
Crocker, K. C., & Hunter, M. D. (2018) · Journal of Insect Physiology · doi:10.1016/j.jinsphys.2018.06.003 · Cited by 19
“Briefly, free ESH are endocrinologically active, and are responsible for driving embryogenesis and cell differentiation; conjugated ESH are endocrinologically inactive, but can be activated by embryos during development (reviewed in (Smagghe, 2009)).”
Background
Ecdysteroid-mimicking compounds act as both agonists and antagonists to the crustacean ecdysone receptor
Chan, Y. H., Chu, K. H., & Chan, K. M. (2019) · Chemosphere · doi:10.1016/j.chemosphere.2019.124551 · Cited by 18
An ecdysone receptor from the pentatomomorphan, Nezara viridula, shows similar affinities for moulting hormones makisterone A and 20-hydroxyecdysone
Tohidi‐Esfahani, D., Graham, L. D., Hannan, G. N., Simpson, A. M., & Hill, R. J. (2010) · Insect Biochemistry and Molecular Biology · doi:10.1016/j.ibmb.2010.10.002 · Cited by 17
Two Adjacent cis-Regulatory Elements Are Required for Ecdysone Response of Ecdysone Receptor (EcR) B1 Transcription
Shirai, H., Kamimura, M., Yamaguchi, J., Imanishi, S., Kojima, T., & Fujiwara, H. (2012) · PLoS ONE · doi:10.1371/journal.pone.0049348 · Cited by 16
Analysis of triterpenes and triterpenoids
Garg, A., Sharma, R., Dey, P. K., Kundu, A. B., Kim, H. S., Bhakta, T., & Kumar, A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-816455-6.00011-1 · Cited by 25
The brown shrimp (Crangon crangon L.) ecdysteroid receptor complex: Cloning, structural modeling of the ligand-binding domain and functional expression in an EcR-deficient Drosophila cell line
Verhaegen, Y., Parmentier, K., Swevers, L., Rougé, P., Soin, T., Coen, W. D., Cooreman, K., & Smagghe, G. J. (2010) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2010.05.007 · Cited by 17
Self-citation
Phytoecdysteroids: Phytochemistry and Pharmacological Activity
Laekeman, G., & Vlietinck, A. J. (2013) · Springer eBooks · doi:10.1007/978-3-642-22144-6_173 · Cited by 17
Characterization of synthetic ecdysteroid analogues as functional mimics of brassinosteroids in plant growth
Thussagunpanit, J., Jutamanee, K., Homvisasevongsa, S., Suksamrarn, A., Yamagami, A., Nakano, T., & Asami, T. (2017) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2017.05.003 · Cited by 15
Cloning and expression pattern of the ecdysone receptor and retinoid X receptor from the centipede Lithobius peregrinus (Chilopoda, Lithobiomorpha)
Bortolin, F., Piulachs, M., Congiu, L., & Fusco, G. (2011) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2011.08.008 · Cited by 16
High-performance thin-layer chromatography and indirect TLC—HRMS-based determination of 20-hydroxyecdysone in Sesuvium portulacastrum
Muchate, N. S., Kadam, N. S., Rajurkar, N. S., & Nikam, T. D. (2017) · Journal of Planar Chromatography – Modern TLC · doi:10.1556/1006.2017.30.3.7 · Cited by 15
Developmental/reproductive effects and gene expression variations in Chironomus riparius after exposure to reclaimed water and its fortification with carbamazepine and triclosan
Planelló, R., Herrero, Ó., García, P., et al. (2020) · Water Research · doi:10.1016/j.watres.2020.115790 · Cited by 15
Biological insights into the rapid tissue regeneration of freshwater crayfish and crustaceans
Feleke, M., Bennett, S., Chen, J., Chandler, D., Hu, X., & Xu, J. (2021) · Cell Biochemistry and Function · doi:10.1002/cbf.3653 · Cited by 15
“In proecdysis, ecdysone levels further increase and peak at 75-135 ng/mL, during which time the basal bud ceases growth.(83,142)”
Background
Insect Hormones (as Pesticides)
Subramanian, S., & Shankarganesh, K. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803265-7.00020-8 · Cited by 15
Sequencing and structural homology modeling of the ecdysone receptor in two chrysopids used in biological control of pest insects
Zotti, M. J., Christiaens, O., Rougé, P., Grützmacher, A. D., Zimmer, P. D., & Smagghe, G. J. (2012) · Ecotoxicology · doi:10.1007/s10646-012-0852-0 · Cited by 15
Self-citation
Aphid growth and reproduction on plants with altered sterol profiles: Novel insights using Arabidopsis mutant and overexpression lines
Chen, I. W., Grebenok, R. J., Schaller, H., Zhu‐Salzman, K., & Behmer, S. T. (2020) · Journal of Insect Physiology · doi:10.1016/j.jinsphys.2020.104054 · Cited by 13
Ecdysteroids in Ferns: Distribution, Diversity, Biosynthesis, and Functions
Lafont, R., Ho, R., Raharivelomanana, P., & Dinan, L. (2010) · Springer eBooks · doi:10.1007/978-1-4419-7162-3_22 · Cited by 13
Conserved Transcription Factors Steer Growth-Related Genomic Programs in Daphnia
Spanier, K. I., Jansen, M. W. J. C., Decaestecker, E., Hulselmans, G. J., Becker, D., Colbourne, J. K., Orsini, L., Meester, L. D., & Aerts, S. (2017) · Genome Biology and Evolution · doi:10.1093/gbe/evx127 · Cited by 15

Authors: Smagghe, G. J.
Affiliations: Ghent University (BE)
Corresponding author: Guy J. Smagghe
ORCID: Guy J. Smagghe
Venue: Springer eBooks
Publisher: Springer Netherlands
Published: 2009
DOI: 10.1007/978-1-4020-9112-4
OpenAlex: W365344764
Cited by: 160
References: 0
Citations by year: 2026: 3 · 2025: 8 · 2024: 3 · 2023: 4 · 2022: 8 · 2021: 12 · 2020: 11 · 2019: 9 · 2018: 9 · 2017: 9 · 2016: 3 · 2015: 12 · 2014: 12 · 2013: 12 · 2012: 15
FWCI: 14.63
Type: book
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Springer eBooks (publishedVersion)
Ghent University Academic Bibliography (Ghent University) (submittedVersion)
Digital Access to Libraries (Université catholique de Louvain (UCL), l'Université de Namur (UNamur) and the Université Saint-Louis (USL-B)) (submittedVersion)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
Physical Sciences › Chemistry › Organic Chemistry › Steroid Chemistry and Biochemistry
Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
Keywords: ecdysone, 20-hydroxyecdysone, insect molting, ecdysteroids, structure-function relationship

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Ecdysone: Structures and Functions

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cited by

Related

Metadata

Record

About these checks