Genetic Influences on Sexual Behavior Differentiation
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Masculinization of the rodent CNS, in contrast to the periphery, is accomplished primarily by the aromatization of testosterone to estrogen.
“Given that the masculinization of the rodent CNS, in contrast to the periphery, is accomplished primarily by the aromatization of testosterone to estrogen (Olsen, 1992, McCarthy, 1994), it is thought that the CNS of the tfm male is largely masculinized and defeminized via this mechanism.”
From Play fighting in androgen-insensitivetfm rats: Evidence that androgen receptors are necessary for the development of adult playful attack and defense (2006) · cites this paper as Olsen, 1992
The CNS of the tfm male is largely masculinized and defeminized via aromatization of testosterone to estrogen.
“Given that the masculinization of the rodent CNS, in contrast to the periphery, is accomplished primarily by the aromatization of testosterone to estrogen (Olsen, 1992, McCarthy, 1994), it is thought that the CNS of the tfm male is largely masculinized and defeminized via this mechanism.”
From Play fighting in androgen-insensitivetfm rats: Evidence that androgen receptors are necessary for the development of adult playful attack and defense (2006) · cites this paper as Olsen, 1992
Cites
PHOENIX, C. H., GOY, R. W., GERALL, A. A., & YOUNG, W. C. (1959) · Endocrinology · doi:10.1210/endo-65-3-369 · Cited by 1,934 · see citing works
X-linked Gene for Testicular Feminization in the Mouse
LYON, M. F., & HAWKES, S. G. (1970) · Nature · doi:10.1038/2271217a0 · Cited by 555 · see citing works
The hormonal-control of sexual development
Wilson, J. D., George, F. W., & Griffin, J. E. (1981) · Science · doi:10.1126/science.7010602 · Cited by 451 · see citing works
WARD, I. L., & WEISZ, J. (1984) · Endocrinology · doi:10.1210/endo-114-5-1635 · Cited by 447 · see citing works
Yarbrough, W. G., Quarmby, V. E., Simental, J. A., Joseph, D. R., Sar, M., Lubahn, D. B., Olsen, K. L., French, F. S., & Wilson, E. M. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)38972-0 · Cited by 199 · see citing works
Self-citationPart I. Male Pseudohermaphroditism in the Laboratory Norway Rat
STANLEY, A. J., GUMBRECK, L. G., ALLISON, J. E., & EASLEY, R. B. (1973) · Proceedings of the 1972 Laurentian Hormone Conference · doi:10.1016/b978-0-12-571129-6.50005-1 · Cited by 80 · see citing works
Olsen, K. L. (1979) · Hormones and Behavior · doi:10.1016/0018-506x(79)90035-7 · Cited by 55 · see citing works
Self-citationShapiro, B. H., Levine, D. C., & Adler, N. T. (1980) · Science · doi:10.1126/science.7384816 · Cited by 41 · see citing works
Endocrine status of the testicular feminized male (TFM) rat
Purvis, K., Haug, E., Clausen, O. P. F., Naess, O., & Hansson, V. (1977) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(77)90006-5 · Cited by 31 · see citing works
Estrogen binds to hypothalamic nuclei of androgen-insensitive (tfm) rats
Olsen, K. L., & Whalen, R. E. (1982) · Experientia · doi:10.1007/bf01944575 · Cited by 17 · see citing works
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Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?
Couse, J. F., & Korach, K. S. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.3.0370 · Cited by 2,045 · see citing works
Bakker, J., Honda, S.-I., Harada, N., & Balthazart, J. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-20-09104.2002 · Cited by 209 · see citing works
Field, E. F., Whishaw, I. Q., Pellis, S. M., & Watson, N. V. (2006) · Developmental Psychobiology · doi:10.1002/dev.20121 · Cited by 30 · see citing works
Field, E. F., Watson, N. V., Whishaw, I. Q., & Pellis, S. M. (2005) · Hormones and Behavior · doi:10.1016/j.yhbeh.2004.08.007 · Cited by 10 · see citing works
- Authors
- Olsen, K. L.
- Affiliations
- U.S. National Science Foundation (US)
- Corresponding author
- Olsen, Kathie L.
- Venue
- Handbooks of Behavioral Neurobiology
- Publisher
- Springer US
- Published
- 1992
- Pages
- 1-40
- ISSN
- 0194-0880 (ISSN-L)
- OpenAlex
- W63492104
- Cited by
- 52
- References
- 10
- Citations by year
- 2025: 1 · 2018: 1 · 2014: 1
- FWCI
- 1.91
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Handbook of behavioral neurobiology (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Sexual Differentiation and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Keywords
- testicular hormones, genetic sex, mating behavior, hormone deprivation, critical developmental periods, sex differences in behavior
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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