Cited by 66Fatty Acid Research and HealthSkin Protection and AgingEdible Oils Quality and Analysis

Influence of fish oil supplementation on the minimal erythema dose in humans

Orengo, I. F., Black, H. S., Wolf, J. E.·1992·Archives of Dermatological Research

Abstract

A previous study using the hairless mouse model demonstrated that diets containing a fish-oil lipid source, which contained high levels of omega-3 fatty acids, markedly increased the minimum erythema dose (MED) when compared with diets containing other polyunsaturated fatty acids. To determine whether fish oil supplementation could produce a similar effect in humans, 20 subjects were randomized into two groups, a placebo group and a group receiving fish-oil supplements over a 4-week period. Results showed a small, but statistically significant, increase in MED in patients whose diet was supplemented with fish oil. Cholesterol and prostaglandin E2 levels were unchanged, while triglyceride levels were significantly decreased in the fish oil group. No significant changes in any of these parameters occurred in the placebo group.

Integrity signals

Registry

Crossref · 10.1007/bf00375797

Cites

23 of 23 references verified0 citation errors · 0 not checkable

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  • Fish oil supplementation containing eicosapentaenoic acid and docosahexaenoic acid increases minimal erythema dose significantly and decreases erythema and p53 induction in human skin.

    “Research suggests that fish oil supplementation (containing eicosapentaenoic acid and docosahexaenoic acid) increases minimal erythema dose significantly and decreases erythema and p53 induction in human skin [132].”

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Authors
Orengo, I. F., Black, H. S., & Wolf, J. E.
Affiliations
Baylor College of Medicine (US)
Venue
Archives of Dermatological Research
Published
1992-08
Volume
284
Issue
4
Pages
219-221
ISSN
  • 0003-9187 (ISSN-L)
  • 0340-3696
  • 1432-069X
OpenAlex
W2042859095
Cited by
66
References
23
Citations by year
2026: 2 · 2025: 5 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 3 · 2020: 2 · 2018: 4 · 2017: 2 · 2016: 2 · 2015: 1 · 2014: 2 · 2013: 5 · 2012: 2
FWCI
0.91
Type
journal article
Language
en
Open access
closed
Locations
  • Archives of Dermatological Research (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
  • Health Sciences › Medicine › Dermatology › Skin Protection and Aging
  • Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
Keywords
fish oil supplementation, omega-3 fatty acids, minimal erythema dose, sun sensitivity, photoprotection, triglycerides, prostaglandin E2, cholesterol, polyunsaturated fatty acids, dietary supplementation
MeSH terms
Adult, Erythema, Female, Fish Oils, Humans, Male, Middle Aged, Ultraviolet Rays, Fatty Acids, Omega-3

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