Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers

A simple technique for quantitation of low levels of DNA damage in individual cells

Singh, N. P., McCoy, M. T., Tice, R. R., & Schneider, E. L. (1988) · Experimental Cell Research · doi:10.1016/0014-4827(88)90265-0 · Cited by 10,828 · see citing works

p53, guardian of the genome

Lane, D. P. (1992) · Nature · doi:10.1038/358015a0 · Cited by 5,138 · see citing works

Participation of p53 protein in the cellular response to DNA damage.

Kastan, M. B., Onyekwere, O. C., Sidransky, D., Vogelstein, B., & Craig, R. W. (1991) · PubMed · Cited by 3,761 · see citing works

Lipid peroxidation: its mechanism, measurement, and significance

Halliwell, B. B., & Chirico, S. (1993) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/57.5.715s · Cited by 2,355 · see citing works

The modification of mammalian membrane polyunsaturated fatty acid composition in relation to membrane fluidity and function

Stubbs, C. D., & Smith, A. D. (1984) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(84)90005-4 · Cited by 1,618 · see citing works

Sunburn and p53 in the onset of skin cancer

Ziegler, A., Jonason, A. S., Leffellt, D. J., Simon, J. A., Sharma, H. W., Kimmelman, J., Remington, L., Jacks, T., & Brash, D. E. (1994) · Nature · doi:10.1038/372773a0 · Cited by 1,497 · see citing works

Sunlight and sunburn in human skin cancer: p53, apoptosis, and tumor promotion.

Brash, D. E., Ziegler, A., Jonason, A. S., Simon, J. A., Kunala, S., & Leffell, D. J. (1996) · PubMed · Cited by 399 · see citing works

Concurrent liquid-chromatographic assay of retinol, alpha-tocopherol, beta-carotene, alpha-carotene, lycopene, and beta-cryptoxanthin in plasma, with tocopherol acetate as internal standard.

Thurnham, D. I., Smith, E., & Flora, P. S. (1988) · Clinical Chemistry · doi:10.1093/clinchem/34.2.377 · Cited by 384 · see citing works

Biochemistry and physiology of n‐3 fatty acids

Lands, W. E. M. (1992) · The FASEB Journal · doi:10.1096/fasebj.6.8.1592205 · Cited by 323 · see citing works

Estimate of the Wavelength Dependency of Ultraviolet Carcinogenesis in Humans and Its Relevance to the Risk Assessment of a Stratospheric Ozone Depletion

de Gruijl, F. R., & van der Leun, J. C. (1994) · Health Physics · doi:10.1097/00004032-199410000-00001 · Cited by 250 · see citing works

Effect of diets high in omega-3 and omega-6 fatty acids on initiation and postinitiation stages of colon carcinogenesis.

Reddy, B. S., Burill, C., & Rigotty, J. (1991) · PubMed · Cited by 244 · see citing works

Early p53 alterations in mouse skin carcinogenesis by UVB radiation: immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells.

Berg, R. J. W., van Kranen, H. J., Rebel, H. G., de Vries, A., van Vloten, W. A., van Kreijl, C. F., van der Leun, J. C., & de Gruijl, F. R. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.1.274 · Cited by 220 · see citing works

Molecular and Cellular Effects of Ultraviolet Light-Induced Genotoxicity

Griffiths, H. R., Mistry, P., Herbert, K. E., & Lunec, J. (1998) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/10408369891234192 · Cited by 207 · see citing works

Fluorometric determination of total vitamin C in whole blood by high-performance liquid chromatography with pre-column derivatization

Speek, A. J., Schrijver, J., & Schreurs, W. H. P. (1984) · Journal of Chromatography B Biomedical Sciences and Applications · doi:10.1016/s0378-4347(00)83313-7 · Cited by 178 · see citing works

Comparative studies by comet test and SCE analysis in human lymphocytes from 200 healthy subjects

Betti, C., Davini, T., Giannessi, L., Loprieno, N., & Barale, R. (1995) · Mutation Research/Genetic Toxicology · doi:10.1016/0165-1218(95)90015-2 · Cited by 147 · see citing works

Determination of steady-state levels of oxidative DNA base modifications in mammalian cells by means of repair endonucleases

Pflaum, M. (1997) · Carcinogenesis · doi:10.1093/carcin/18.11.2225 · Cited by 143 · see citing works

Dietary Fish Oil Reduces Basal and Ultraviolet B-Generated PGE2 Levels in Skin and Increases the Threshold to Provocation of Polymorphic Light Eruption

Rhodes, L. E., Durham, B., Fraser, W. D., & Friedmann, P. S. (1995) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12323389 · Cited by 141 · see citing works

DETECTION OF CYCLOBUTANE THYMINE DIMERS IN DNA OF HUMAN CELLS WITH MONOCLONAL ANTIBODIES RAISED AGAINST A THYMINE DIMER‐ CONTAINING TETRANUCLEOTIDE

Roza, L., Kj, V. D. W., MacFarlane, S. J., Lohman, P. H. M., & Baan, R. A. (1988) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1988.tb02873.x · Cited by 136 · see citing works

Ultraviolet-B-Induced Erythema is Mediated by Nitric Oxide and Prostaglandin E2 in Combination

Rhodes, L. E., Belgi, G., Parslew, R., McLoughlin, L., Clough, G. F., & Friedmann, P. S. (2001) · Journal of Investigative Dermatology · doi:10.1046/j.0022-202x.2001.01514.x · Cited by 129 · see citing works

Down-regulation of protein and mRNA expression for transforming growth factor-β (TGF-β1) type I and type II receptors in human prostate cancer

Guo, Y., Jacobs, S. C., & Kyprianou, N. (1997) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19970516)71:4 · Cited by 129 · see citing works

Dietary fish-oil supplementation in humans reduces UVB-erythemal sensitivity but increases epidermal lipid peroxidation

Rhodes, L. E., Friedmann, P. S., O'Farrell, S., & Jackson, M. J. (1994) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12392604 · Cited by 122 · see citing works

Resistance to apoptosis in human cells conferred by telomerase function and telomere stability

Holt, S. E., Glinsky, V. V., Ivanova, A. B., & Glinsky, G. V. (1999) · Molecular Carcinogenesis · doi:10.1002/(sici)1098-2744(199908)25:4 · Cited by 118 · see citing works

INFLUENCE OF DIETARY OMEGA‐6, ‐3 FATTY ACID SOURCES ON THE INITIATION AND PROMOTION STAGES OF PHOTOCARCINOGENESIS

Black, H. S., Thornby, J. I., Gerguis, J., & Lenger, W. (1992) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1992.tb02147.x · Cited by 93 · see citing works

Diet and melanoma an exploratory case-control study

Bain, C. J., Green, A. C., Siskind, V., Alexander, J., & Harvey, P. W. (1993) · Annals of Epidemiology · doi:10.1016/1047-2797(93)90024-x · Cited by 84 · see citing works

Eicosapentaenoic Acid, a n-3 Polyunsaturated Fatty Acid Differentially Modulates TNF-α, IL-1α, IL-6 and PGE2 Expression in UVB-Irradiated Human Keratinocytes

Pupe, A., Haes, P. D., Rhodes, L. E., Garmyn, M., Moison, R. M. W., van Henegouwen, G. B., & Degreef, H. J. (2002) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2002.01615.x · Cited by 82 · see citing works

Hypersensitivity of human lymphocytes to UV-B and solar irradiation.

Arlett, C. F., Lowe, J. E., Harcourt, S. A., Waugh, A. P. W., Cole, J., Roza, L., Diffey, B. L., Mori, T., Nikaido, O., & Green, M. H. L. (1993) · PubMed · Cited by 81 · see citing works

Seasonal variation of DNA damage and repair in patients with non-melanoma skin cancer and referents with and without psoriasis

Møller, P. (1998) · Mutation Research/DNA Repair · doi:10.1016/s0921-8777(97)00057-8 · Cited by 78 · see citing works

Increased n-3 polyunsaturated fatty acid content of red blood cells from fish oil-fed rabbits increases in vitro lipid peroxidation, but decreases hemolysis

van den Berg, J. J. M., de Fouw, N. J., Kuypers, F. A., Roelofsen, B., Houtsmuller, U. M. T., & den Kamp, J. A. F. O. (1991) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(91)90156-w · Cited by 78 · see citing works

INFLUENCE OF DIETARY MENHADEN OIL UPON CARCINOGENESIS AND VARIOUS CUTANEOUS REspONSES TO ULTRAVIOLET RADIATION*

Orengo, I. F., Black, H. S., Kettler, A. H., & Wolf, J. E. (1989) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1989.tb04080.x · Cited by 70 · see citing works

MODIFICATION OF MEMBRANE COMPOSITION, EICOSANOID METABOLISM, AND IMMUNORESPONSIVENESS BY DIETARY OMEGA‐3 AND OMEGA‐6 FATTY ACID SOURCES, MODULATORS OF ULTRAVIOLET‐CARCINOGENESIS

Fischer, M. A., & Black, H. S. (1991) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1991.tb02031.x · Cited by 67 · see citing works

Influence of fish oil supplementation on the minimal erythema dose in humans

Orengo, I. F., Black, H. S., & Wolf, J. E. (1992) · Archives of Dermatological Research · doi:10.1007/bf00375797 · Cited by 66 · see citing works

Identification and quantification of intermediates of unsaturated fatty acid metabolism in plasma of patients with fatty acid oxidation disorders

Onkenhout, W., Venizelos, V., van der Poel, P. F. H., van den Heuvel, M. P., & Poorthuis, B. J. H. M. (1995) · Clinical Chemistry · doi:10.1093/clinchem/41.10.1467 · Cited by 59 · see citing works

Ultraviolet-induced DNA excision repair in human B and T lymphocytes II. Effect of inhibitors and DNA precursors

Yew, F. F.-H., & Johnson, R. T. (1979) · Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis · doi:10.1016/0005-2787(79)90170-9 · Cited by 55 · see citing works

Detection of Photorepair of UV-Induced Thymine Dimers in Human Epidermis by Immunofluorescence Microscopy

Roza, L., de Gruijl, F. R., Henegouwen, J. B. A. B., Guikers, K. L. H., van Weelden, H., van der Schans, G. P., & Baan, R. A. (1990) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12475429 · Cited by 55 · see citing works

Menhaden Fish Oil, n-3 Polyunsaturated Fatty Acids, and Protection of Newborn Rats from Oxygen Toxicity

Sosenko, I. R. S., Innis, S. M., & Frank, L. (1989) · Pediatric Research · doi:10.1203/00006450-198904000-00019 · Cited by 53 · see citing works

Determination of glutathione in biological material by flow-injection analysis using an enzymatic recycling reaction

Redegeld, F. A., van Opstal, M. A. J., Houdkamp, E., & Bennekom, W. P. V. (1988) · Analytical Biochemistry · doi:10.1016/0003-2697(88)90048-6 · Cited by 52 · see citing works

Ascorbic and dehydroascorbic acids simultaneously quantified in biological fluids by liquid chromatography with fluorescence detection, and comparison with a colorimetric assay.

Lopez‐Anaya, A., & Mayersohn, M. (1987) · Clinical Chemistry · doi:10.1093/clinchem/33.10.1874 · Cited by 49 · see citing works

Assessment of the Effects of Various UV Sources on Inactivation and Photoproduct Induction in Phage T7 Dosimeter

Fekete, A., Vink, A. A., Gáspár, S., Bérces, A., Módos, K., Rontó, G., & Roza, L. (1998) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1998.tb02509.x · Cited by 44 · see citing works

Influence of omega‐3 and omega‐6 fatty acid sources on prostaglandin levels in mice

Henderson, C. D., Black, H. S., & Wolf, J. E. (1989) · Lipids · doi:10.1007/bf02535129 · Cited by 42 · see citing works

Dietary Eicosapentaenoic Acid Prevents Systemic Immunosuppression in Mice Induced by UVB Radiation

Moison, R. M. W., & van Henegouwen, G. M. J. B. (2001) · Radiation Research · doi:10.1667/0033-7587(2001)156[0036:deapsi]2.0.co;2 · Cited by 37 · see citing works

Dependence of photocarcinogenesis and photoimmunosuppression in the hairless mouse on dietary polyunsaturated fat

Reeve, V. E., Bosnic, M., & Boehm‐Wilcox, C. (1996) · Cancer Letters · doi:10.1016/s0304-3835(96)04460-6 · Cited by 35 · see citing works

Topical and systemic approaches for protection against solar radiation-induced skin damage

Rhodes, L. E. (1998) · Clinics in Dermatology · doi:10.1016/s0738-081x(97)00171-5 · Cited by 33 · see citing works

Ingestion of eicosapentaenoic acid-ethyl ester renders rabbit LDL less susceptible to Cu2+-catalyzed-oxidative modification

Saito, H., Chang, K., Tamura, Y., & Yoshida, S. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(05)81200-8 · Cited by 19 · see citing works

UV/induced alterations in skin and lymphocytes during a one/week holiday in the Canary Islands in May.

Bech-Thomsen, N., Munch‐Petersen, B., Lundgren, K., Poulsen, T., & Wulf, H. C. (1993) · Acta Dermato Venereologica · doi:10.2340/0001555573422425 · Cited by 18 · see citing works

The omega-3 fatty acid peroxidation paradox

Budowski, P. (1996) · Redox Report · doi:10.1080/13510002.1996.11747030 · Cited by 16 · see citing works

Systemic photoprotective agents.

Black, H. S. (1987) · PubMed · Cited by 15 · see citing works

Photoageing: mechanism, prevention and therapy

Yaar, M., & Gilchrest, B. A. (2007) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2007.08108.x · Cited by 755 · see citing works

Inflammation, gene mutation and photoimmunosuppression in response to UVR-induced oxidative damage contributes to photocarcinogenesis

Halliday, G. M. (2005) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2004.09.013 · Cited by 439 · see citing works

Multi-targeted therapy of cancer by omega-3 fatty acids

Berquin, I. M., Edwards, I. J., & Chen, Y. Q. (2008) · Cancer Letters · doi:10.1016/j.canlet.2008.03.044 · Cited by 362 · see citing works

Bioactive Compounds for Skin Health: A Review

Michalak, M., Pierzak, M., Kręcisz, B., & Suliga, E. (2021) · Nutrients · doi:10.3390/nu13010203 · Cited by 345 · see citing works

Nutritional protection against skin damage from sunlight

Sies, H., & Stahl, W. (2004) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.24.012003.132320 · Cited by 307 · see citing works

Bioactive Compounds Isolated from Microalgae in Chronic Inflammation and Cancer

Talero, E., García‐Mauriño, S., Ávila‐Román, J., Rodríguez-Luna, A., Alcaide, A. M., & Motilva, V. (2015) · Marine Drugs · doi:10.3390/md13106152 · Cited by 258 · see citing works

Bioactive lipid mediators in skin inflammation and immunity

Kendall, A. C., & Nicolaou, A. (2013) · Progress in Lipid Research · doi:10.1016/j.plipres.2012.10.003 · Cited by 229 · see citing works

Healing fats of the skin: the structural and immunologic roles of the ω-6 and ω-3 fatty acids

McCusker, M. M., & Grant-Kels, J. M. (2010) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2010.03.020 · Cited by 227 · see citing works

Cyclooxygenases in the skin: pharmacological and toxicological implications

Lee, J. L., Mukhtar, H., Bickers, D. R., Kopelovich, L., & Athar, M. (2003) · Toxicology and Applied Pharmacology · doi:10.1016/s0041-008x(03)00301-6 · Cited by 189 · see citing works

Altered cholesterol and fatty acid metabolism in Huntington disease

Block, R. C., Dorsey, E. R., Beck, C. A., Brenna, J. T., & Shoulson, I. (2010) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2009.11.003 · Cited by 152 · see citing works

Dietary antioxidants and beneficial effect on oxidatively damaged DNA

Möller, P., & Loft, S. H. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.04.001 · Cited by 146 · see citing works

Oral nicotinamide protects against ultraviolet radiation-induced immunosuppression in humans

Yiasemides, E., Sivapirabu, G., Halliday, G. M., Park, J., & Damian, D. L. (2008) · Carcinogenesis · doi:10.1093/carcin/bgn248 · Cited by 134 · see citing works

The Role of Essential Fatty Acids in Human Health

Glick, N. R., & Fischer, M. H. (2013) · Journal of Evidence-Based Complementary & Alternative Medicine · doi:10.1177/2156587213488788 · Cited by 121 · see citing works

The sunburn response in human skin is characterized by sequential eicosanoid profiles that may mediate its early and late phases

Rhodes, L. E., Gledhill, K., Masoodi, M., Haylett, A. K., Brownrigg, M., Thody, A. J., Tobin, D. J., & Nicolaou, A. (2009) · The FASEB Journal · doi:10.1096/fj.09-136077 · Cited by 118 · see citing works

A protective effect of the Mediterranean diet for cutaneous melanoma

Fortes, C., Mastroeni, S., Melchi, F., Pilla, M. A., Antonelli, G., Camaioni, D., Alotto, M., & Pasquini, P. (2008) · International Journal of Epidemiology · doi:10.1093/ije/dyn132 · Cited by 115 · see citing works

Omega-3 Polyunsaturated Fatty Acids and Cancer

Jing, K., Wu, T., & Lim, K. (2013) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/18715206113139990319 · Cited by 108 · see citing works

Eicosapentaenoic Acid and Docosahexaenoic Acid Reduce UVB- and TNF-α-induced IL-8 Secretion in Keratinocytes and UVB-induced IL-8 in Fibroblasts

Storey, A., McArdle, F., Friedmann, P. S., Jackson, M. J., & Rhodes, L. E. (2005) · Journal of Investigative Dermatology · doi:10.1111/j.0022-202x.2004.23543.x · Cited by 102 · see citing works

Omega‐3 polyunsaturated fatty acids: photoprotective macronutrients

Pilkington, S. M., Watson, R. E. B., Nicolaou, A., & Rhodes, L. E. (2011) · Experimental Dermatology · doi:10.1111/j.1600-0625.2011.01294.x · Cited by 94 · see citing works

New Strategies of Photoprotection

Verschooten, L., Claerhout, S., Laethem, A. V., Agostinis, P., & Garmyn, M. (2006) · Photochemistry and Photobiology · doi:10.1562/2006-04-27-ir-884.1 · Cited by 94 · see citing works

Ultraviolet-radiation induced skin inflammation: dissecting the role of bioactive lipids

Nicolaou, A., Pilkington, S. M., & Rhodes, L. E. (2011) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2011.04.005 · Cited by 79 · see citing works

Prostaglandin E3 metabolism and cancer

Yang, P., Jiang, Y., & Fischer, S. M. (2014) · Cancer Letters · doi:10.1016/j.canlet.2014.03.010 · Cited by 77 · see citing works

Docosahexaenoic acid enhances the antioxidant response of human fibroblasts by upregulating γ-glutamyl-cysteinyl ligase and glutathione reductase

Arab, K., Rossary, A., Flourié, F., Tourneur, Y., & Steghens, J. (2006) · British Journal Of Nutrition · doi:10.1079/bjn20051626 · Cited by 79 · see citing works

Cytotoxic Activity of Fatty Acids From Antarctic Macroalgae on the Growth of Human Breast Cancer Cells

Pacheco, B. S., dos Santos, M. A. Z., Schultze, E., Martins, R. M., Lund, R. G., Seixas, F. K., Colepicolo, P., Collares, T. V., Paula, F. R., & de Pereira, C. M. P. (2018) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2018.00185 · Cited by 74 · see citing works

The potential of omega-3 fatty acids in the prevention of non-melanoma skin cancer

Black, H. S., & Rhodes, L. E. (2006) · Cancer Detection and Prevention · doi:10.1016/j.cdp.2006.04.008 · Cited by 69 · see citing works

Effect of a nutritional supplement on hair loss in women

Floc'h, C. L., Cheniti, A., Connétable, S., Piccardi, N., Vincenzi, C., & Tosti, A. (2015) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.12127 · Cited by 68 · see citing works

Scientific Opinion on the substantiation of health claims related to eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), docosapentaenoic acid (DPA) and maintenance of normal cardiac function (ID 504, 506, 516, 527, 538, 703, 1128, 1317, 1324, 1325): EPA/DHA/DPA related health claims

EFSA Panel on Dietetic Products, N. A. A. (. (2010) · EFSA Journal · doi:10.2903/j.efsa.2010.1796 · Cited by 65 · see citing works

Nutritional Neuroscience as Mainstream of Psychiatry: The Evidence- Based Treatment Guidelines for Using Omega-3 Fatty Acids as a New Treatment for Psychiatric Disorders in Children and Adolescents

Chang, J. P., & Su, K. (2020) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2020.18.4.469 · Cited by 65 · see citing works

Influence of Eicosapentaenoic Acid, an Omega-3 Fatty Acid, on Ultraviolet-B Generation of Prostaglandin-E2 and Proinflammatory Cytokines Interleukin-1β, Tumor Necrosis Factor–α, Interleukin-6 and Interleukin-8 in Human Skin In Vivo¶

Shahbakhti, H., Watson, R. E. B., Azurdia, R. M., Ferreira, C. Z., Garmyn, M., & Rhodes, L. E. (2004) · Photochemistry and Photobiology · doi:10.1562/2004-01-27-ra-066.1 · Cited by 60 · see citing works

Diet in dermatology

Murzaku, E. C., Bronsnick, T., & Rao, B. K. (2014) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2014.06.016 · Cited by 60 · see citing works

Wrinkle reduction in post‐menopausal women consuming a novel oral supplement: a double‐blind placebo‐controlled randomized study

Jenkins, G., Wainwright, L., Holland, R. L., Barrett, K. E., & Casey, J. (2013) · International Journal of Cosmetic Science · doi:10.1111/ics.12087 · Cited by 51 · see citing works

Treatment of polymorphic light eruption

Ling, T. C., Gibbs, N. K., & Rhodes, L. E. (2003) · Photodermatology Photoimmunology & Photomedicine · doi:10.1034/j.1600-0781.2003.00048.x · Cited by 51 · see citing works

Consumption of omega‐3 fatty acids and the risk of skin cancers: A systematic review and meta‐analysis

Noël, S., Stoneham, A. C. S., Olsen, C. M., Rhodes, L. E., & Green, A. C. (2013) · International Journal of Cancer · doi:10.1002/ijc.28630 · Cited by 50 · see citing works

Effects of Zinc and DHA on the Epigenetic Regulation of Human Neuronal Cells

Sadli, N., Ackland, M. L., Mel, D. D., Sinclair, A. J., & Suphioglu, C. (2012) · Cellular Physiology and Biochemistry · doi:10.1159/000337590 · Cited by 49 · see citing works

Impact of EPA ingestion on COX ‐ and LOX ‐mediated eicosanoid synthesis in skin with and without a pro‐inflammatory UVR challenge – Report of a randomised controlled study in humans

Pilkington, S. M., Rhodes, L. E., Al‐Aasswad, N. M. I., Massey, K. A., & Nicolaou, A. (2013) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201300405 · Cited by 50 · see citing works

Omega-3 polyunsaturated fatty acids for major depressive disorder

Su, K., Wang, S., & Pae, C. (2013) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.2013.836487 · Cited by 47 · see citing works

Randomized controlled trial of oral omega-3 PUFA in solar-simulated radiation-induced suppression of human cutaneous immune responses

Pilkington, S. M., Massey, K. A., Bennett, S., Al‐Aasswad, N. M. I., Roshdy, K., Gibbs, N. K., Friedmann, P. S., Nicolaou, A., & Rhodes, L. E. (2013) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.049494 · Cited by 45 · see citing works

Nrf2 deficiency causes lipid oxidation, inflammation, and matrix-protease expression in DHA-supplemented and UVA-irradiated skin fibroblasts

Gruber, F., Ornelas, C. M., Karner, S., Narzt, M.-S., Nagelreiter, I. M., Gschwandtner, M., Bochkov, V., & Tschachler, E. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.05.006 · Cited by 44 · see citing works

Potential Benefits of Omega-3 Fatty Acids in Non-Melanoma Skin Cancer

Black, H. S., & Rhodes, L. E. (2016) · Journal of Clinical Medicine · doi:10.3390/jcm5020023 · Cited by 44 · see citing works

Influence of oral antioxidants on ultraviolet radiation‐induced skin damage in humans

Swindells, K. J., & Rhodes, L. E. (2004) · Photodermatology Photoimmunology & Photomedicine · doi:10.1111/j.1600-0781.2004.00121.x · Cited by 44 · see citing works

Oral supplementation with fish oil reduces dryness and pruritus in the acetone-induced dry skin rat model

Barcelos, R. C. S., de Mello-Sampayo, C., Antoniazzi, C. T. D. D., Segat, H. J., Silva, H., Veit, J. C., Piccolo, J., Emanuelli, T., Bürger, M. E., Lima, B. S., et al. (2015) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2015.06.015 · Cited by 43 · see citing works

The Potential Uses of Omega-3 Fatty Acids in Dermatology: A Review

Thomsen, B. J., Chow, E. Y., & Sapijaszko, M. (2020) · Journal of Cutaneous Medicine and Surgery · doi:10.1177/1203475420929925 · Cited by 42 · see citing works

Prospective Study of Dietary Fat and Risk of Cataract Extraction among US Women

Lu, M., Cho, E., Taylor, A., Hankinson, S. E., Willett, W. C., & Jacques, P. F. (2005) · American Journal of Epidemiology · doi:10.1093/aje/kwi118 · Cited by 42 · see citing works

Untitled work

Andreeva (2012) · doi:10.1001/archinternmed.2011.1450 · Cited by 40 · see citing works

Dietary polychlorinated biphenyls, long-chain n-3 polyunsaturated fatty acids and incidence of malignant melanoma

Donat‐Vargas, C., Berglund, M., Glynn, A. W., Wolk, A., & Åkesson, A. (2016) · European Journal of Cancer · doi:10.1016/j.ejca.2016.11.016 · Cited by 38 · see citing works

Food intake, dietary patterns, and actinic keratoses of the skin: a longitudinal study

Hughes, M. C. B., Williams, G. M., Fourtanier, A. M., & Green, A. C. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.27053 · Cited by 36 · see citing works

Docosahexaenoic Acid Induces Expression of Heme Oxygenase-1 and NAD(P)H:quinone Oxidoreductase through Activation of Nrf2 in Human Mammary Epithelial Cells

Bang, H.-Y., Park, S., Saeidi, S., Na, H., & Surh, Y. (2017) · Molecules · doi:10.3390/molecules22060969 · Cited by 35 · see citing works

Association between dietary intake of n-3 polyunsaturated fatty acids and severity of skin photoaging in a middle-aged Caucasian population

Latreille, J., Kesse‐Guyot, E., Malvy, D. J.-M., Andreeva, V. A., Galan, P., Tschachler, E., Herçberg, S., Guinot, C., & Ezzedine, K. (2013) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2013.07.006 · Cited by 35 · see citing works

Docosahexaenoic acid reverts resistance to UV-induced apoptosis in human keratinocytes: involvement of COX-2 and HuR

Serini, S., Donato, V., Piccioni, E., Trombino, S., Monego, G., Toesca, A., Innocenti, I., Missori, M., Spirito, M. D., Celleno, L., et al. (2010) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2010.08.004 · Cited by 34 · see citing works

Small-molecule targeting of translation initiation for cancer therapy

Aktas, B. H., Qiao, Y., Özdelen, E., Schubert, R., Sevinc, S., Harbinski, F., Grubissich, L., Singer, S., & Halperin, J. A. (2013) · Oncotarget · doi:10.18632/oncotarget.1186 · Cited by 30 · see citing works

Ethyl-EPA in Huntington disease—Potentially relevant mechanism of action

Murck, H., & Manku, M. S. (2006) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2006.10.020 · Cited by 30 · see citing works

Skin Protective Nutraceuticals: The Current Evidence in Brief

Nwanodi, O. B. (2018) · Healthcare · doi:10.3390/healthcare6020040 · Cited by 25 · see citing works

Riboflavin-photosensitized oxidation is enhanced by conjugation in unsaturated lipids

Skibsted, L. H. (2013) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) · doi:10.1021/jf305280x

Conjugated linoleic acids modulate UVR-induced IL-8 and PGE2 in human skin cells: potential of CLA isomers in nutritional photoprotection

Storey, A., Rogers, J. S., McArdle, F., Jackson, M. J., & Rhodes, L. E. (2007) · Carcinogenesis · doi:10.1093/carcin/bgm065 · Cited by 24 · see citing works

Functional food ingredients as adjunctive therapies to pharmacotherapy for treating disorders of metabolic syndrome

Marinangeli, C. P. F., & Jones, P. J. H. (2010) · Annals of Medicine · doi:10.3109/07853890.2010.484026 · Cited by 23 · see citing works

Influence of Omega-3 Fatty Acid-Rich Fish Oils on Hyperlipidemia: Effect of Eel, Sardine, Trout, and Cod Oils on Hyperlipidemic Mice

Kontostathi, M., Isou, S., Mostratos, D., Vasdekis, V., Demertzis, N. S., Kourounakis, A. P., Vitsos, A., Kyriazi, M., Melissos, D., Tsitouris, C., et al. (2020) · Journal of Medicinal Food · doi:10.1089/jmf.2020.0114 · Cited by 22 · see citing works

Inhibitory activity of flaxseed oil against CdCl2 induced liver and kidney damage: Histopathology, genotoxicity, and gene expression study

Diab, K. A. E., Ibrahim, N. E., Fahmy, M. A., Hassan, E. M., & Omara, E. A. A. (2020) · Toxicology Reports · doi:10.1016/j.toxrep.2020.08.023 · Cited by 22 · see citing works

Nicaraven Attenuates Radiation-Induced Injury in Hematopoietic Stem/Progenitor Cells in Mice

Kawakatsu, M., Urata, Y., Imai, R., Goto, S., Ono, Y., Nishida, N., & Li, T. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060023 · Cited by 22 · see citing works

Diet and Dermatology: The Role of a Whole-food, Plant-based Diet in Preventing and Reversing Skin Aging-A Review.

Solway, J., McBride, M., Haq, F., Waheed, A., & Miller, R. (2020) · PubMed Central · Cited by 19 · see citing works

Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial

Miura, K., Vail, A., Chambers, D. C., Hopkins, P. M.-A., Ferguson, L. E., Grant, M., Rhodes, L. E., & Green, A. C. (2018) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2018.09.009 · Cited by 19 · see citing works

The Role of Nutraceuticals and Functional Foods in Skin Cancer: Mechanisms and Therapeutic Potential

Peterle, L., Sanfilippo, S., Borgia, F., Pomi, F. L., Vadalà, R., Costa, R., Cicero, N., & Gangemi, S. (2023) · Foods · doi:10.3390/foods12132629 · Cited by 17 · see citing works

Serum Omega-3 and Omega-6 Fatty Acids and Cutaneous p53 Expression in an Australian Population

van der Pols, J. C., Xu, C., Boyle, G. M., Hughes, M. C. B., Carr, S. J., Parsons, P. G., & Green, A. C. (2011) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-10-0961 · Cited by 15 · see citing works

17-Oxo-docosahexaenoic acid induces Nrf2-mediated expression of heme oxygenase-1 in mouse skin in vivo and in cultured murine epidermal cells

Jamil, M. U., Kim, J., Yum, H.-W., Kim, S. H., Kim, S., Kim, D., Cho, N.-C., Na, H., & Surh, Y. (2019) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2019.108156 · Cited by 16 · see citing works

A Importância dos Ácidos Graxos Ômega-3 no Câncer

Carmo, M. C. N. S., & Correia, M. I. T. D. (2009) · Revista Brasileira de Cancerologia · doi:10.32635/2176-9745.rbc.2009v55n3.1621 · Cited by 16 · see citing works

Plasma Omega-3 and Omega-6 Concentrations and Risk of Cutaneous Basal and Squamous Cell Carcinomas in Australian Adults

Wallingford, S. C., Hughes, M. C. B., Green, A. C., & van der Pols, J. C. (2013) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-13-0434 · Cited by 16 · see citing works

Omega-3 fatty acid intake and decreased risk of skin cancer in organ transplant recipients

Miura, K., Way, M., Jiyad, Z., Marquart, L., Plasmeijer, E. I., Campbell, S. B., Isbel, N. M., Fawcett, J., Ferguson, L. E., Davis, M., et al. (2020) · European Journal of Nutrition · doi:10.1007/s00394-020-02378-y · Cited by 15 · see citing works

Intake of Omega-3 and Omega-6 Fatty Acids and Risk of Basal and Squamous Cell Carcinomas of the Skin: A Longitudinal Community-Based Study in Australian Adults

Wallingford, S. C., van As, J. A., Hughes, M. C. B., Ibiebele, T. I., Green, A. C., & van der Pols, J. C. (2012) · Nutrition and Cancer · doi:10.1080/01635581.2012.713540 · Cited by 15 · see citing works

Transformative applications of oculomics-based AI approaches in the management of systemic diseases: A systematic review

Li, Z., Yin, S., Wang, S., Wang, Y., Qiang, W., & Jiang, J. (2024) · Journal of Advanced Research · doi:10.1016/j.jare.2024.11.018 · Cited by 14 · see citing works

Nutraceutical eicosapentaenoic acid in treatment-resistant depression: The psychoneuroimmunity and clinical implications

Chang, J. P., Iqbal, A. Z., Do, Q. L., Yaseen, M., Wu, S., Malau, I. A., Zailani, H., & Su, K. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107857 · Cited by 13 · see citing works

Nutraceuticals and skin appearance: Is there any evidence to support this growing trend?

Spiro, A., & Lockyer, S. (2018) · Nutrition Bulletin · doi:10.1111/nbu.12304 · Cited by 13 · see citing works

Influence of Eicosapentaenoic Acid, an Omega‐3 Fatty Acid, on Ultraviolet‐B Generation of Prostaglandin‐E2 and Proinflammatory Cytokines Interleukin‐1β, Tumor Necrosis Factor‐α, Interleukin‐6 and Interleukin‐8 in Human Skin In Vivo¶

Shahbakhti, H., Watson, R. E. B., Azurdia, R. M., Ferreira, C. Z., Garmyn, M., & Rhodes, L. E. (2004) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2004.tb00076.x · Cited by 13 · see citing works

Can diet prevent nonmelanoma skin cancer progression?

Black, H. S. (2005) · Expert Review of Anticancer Therapy · doi:10.1586/14737140.5.5.801 · Cited by 13 · see citing works

EPA attenuates ultraviolet radiation-induced downregulation of aquaporin-3 in human keratinocytes

Jeon, B., Kang, M., Lee, G.-T., Lee, K.-K., Lee, H.-S., Woo, W.-H., & Mun, Y. (2014) · Archives of Pharmacal Research · doi:10.1007/s12272-014-0482-6 · Cited by 11 · see citing works

Effects of global change factors on fatty acids and mycosporine‐like amino acid production in Chroothece richteriana (Rhodophyta)

González‐Silvera, D., Pérez, S., Korbee, N., Figueroa, F. L., Asencio, A. D., Aboal, M., & López‐Jiménez, J. Á. (2017) · Journal of Phycology · doi:10.1111/jpy.12560 · Cited by 11 · see citing works

Three-way assessment of long-chain n-3 PUFA nutrition: by questionnaire and matched blood and skin samples

Wallingford, S. C., Pilkington, S. M., Massey, K. A., Al‐Aasswad, N. M. I., Ibiebele, T. I., Hughes, M. C. B., Bennett, S., Nicolaou, A., Rhodes, L. E., & Green, A. C. (2012) · British Journal Of Nutrition · doi:10.1017/s0007114512001997 · Cited by 10 · see citing works

An open‐label clinical trial assessing the efficacy and safety of Bend Skincare Anti‐Aging Formula on minimal erythema dose in skin

Morse, N. L., Reid, A., & St‐Onge, M. (2017) · Photodermatology Photoimmunology & Photomedicine · doi:10.1111/phpp.12350 · Cited by 10 · see citing works

Fatty acid profile of the fat in selected smoked marine fish.

Regulska−Ilow, B., Ilow, R., Konikowska, K., Kawicka, A., Różańska, D., & Bochińska, A. (2013) · PubMed · Cited by 9 · see citing works

Positive Association Between DNA Strand Breaks in Peripheral Blood Mononuclear Cells and Polyunsaturated Fatty Acids in Red Blood Cells From Women

Thorlaksdottir, A. Y., Jónsson, J. J., Tryggvadóttír, L., Skúladóttir, G. V., Pétursdóttir, A. L., Ogmundsdottir, H. M., Eyfjord, J. E., & Harðardóttir, I. (2007) · Nutrition and Cancer · doi:10.1080/01635580701365092 · Cited by 8 · see citing works

Chemoprevention of Keratinocyte Carcinomas: An Updated Review

Mounessa, J. S., Qin, R., Dunnick, C. A., & Dellavalle, R. P. (2016) · American Journal of Clinical Dermatology · doi:10.1007/s40257-016-0208-2 · Cited by 8 · see citing works

Omega-3 Fatty Acids and Skin

Pilkington, S. M., & Rhodes, L. E. (2010) · Springer eBooks · doi:10.1007/978-3-642-12264-4_9 · Cited by 7 · see citing works

The role of nutritional lipids and antioxidants in UV-induced skin cancer

Black, H. S. (2015) · Frontiers in Bioscience-Scholar · doi:10.2741/s422 · Cited by 7 · see citing works

Trans Fat Supplementation Increases UV‐Radiation‐Induced Oxidative Damage on Skin of Mice

Barcelos, R. C. S., Segat, H. J., Benvegnú, D. M., Trevizol, F., Roversi, K., Dolci, G. S., Dias, V. T., Piccolo, J., Veit, J. C., Emanuelli, T., et al. (2013) · Lipids · doi:10.1007/s11745-013-3802-6 · Cited by 6 · see citing works

Cloning and functional analysis of Δ6 ‐desaturase gene and its upstream region from Mortierella sp. AGED

Tan, L., Li, S., Zhang, X., & Ma, F. (2014) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.7043 · Cited by 5 · see citing works

GAS CHROMATOGRAPHY STUDY OF N-HEXANE AND CHLOROFORM FRACTIONS OF ETHANOL EXTRACT OF MELASTOMA MALABATHRICUM L. LEAVES: AN IN VITRO STUDY OF ANTIOXIDANT AND SPF VALUES

Apridamayanti, P., Pratiwi, L., & Sari, R. (2022) · International Journal of Pharmacy and Pharmaceutical Sciences · doi:10.22159/ijpps.2022v14i3.43801 · Cited by 5 · see citing works

Preventive oncology

Rhodes, L. E. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16272-7 · Cited by 5 · see citing works

Nutritional abrogation of photoimmunosuppression:in vivoinvestigations

Pilkington, S. M., Gibbs, N. K., Friedmann, P. S., & Rhodes, L. E. (2013) · Photodermatology Photoimmunology & Photomedicine · doi:10.1111/phpp.12091 · Cited by 4 · see citing works

Dermatologic Surgery and Procedures

Vereecken, P. (2018) · InTech eBooks · doi:10.5772/66008 · Cited by 4 · see citing works

Interaction between omega 3 PUFA and UVB radiation: Photoprotective effect in normal and tumoral murine melanocytes?

Vasconcelos, R. O., Bustos, S. O., Gonzalez, J. R., Soares, C. W., Barbosa, M. D., Chammas, R. J., Votto, A. P. D. S., & Trindade, G. S. (2016) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2016.09.043 · Cited by 3 · see citing works

Comparative study of oral administration of Sacha Inchi oil extraction with erythromycin versus oral erythromycin on the treatment of Acne Vulgaris

Suthiphasil, P., Rintha, J., Nararatwanchai, T., & Sittiprapaporn, P. (2018) · Joint International Conference on Digital Arts, Media and Technology with ECTI Northern Section Conference on Electrical, Electronics, Computer and Telecommunications Engineering (ECTI DAMT & NCON) · doi:10.1109/icdamt.2018.8376546 · Cited by 3 · see citing works

Omega-3 fatty acids and non-melanoma skin cancer

Black, H. S. (2012) · Human health handbooks · doi:10.3920/978-90-8686-729-5_22 · Cited by 3 · see citing works

Reduction of risk for lifestyle diseases: group diet and physical activity intervention in the workplace

Cumin, M. B. (2004) · Tuwhera (Auckland University of Technology) · Cited by 3 · see citing works

Skin cancer epidemic in a wireless world

Logan, A. C., & Hallberg, Ö. (2010) · Pathophysiology · doi:10.1016/j.pathophys.2010.02.002 · Cited by 2 · see citing works

Beyond sun protection factor testing

Rhodes, L. E., & Callaghan, T. M. (2004) · International Journal of Cosmetic Science · doi:10.1111/j.1467-2494.2004.00222.x · Cited by 2 · see citing works

Polyunsaturated Fatty Acid Oxygenated Metabolites in Skin

Nicolaou, A. (2014) · Springer eBooks · doi:10.1007/978-3-319-09943-9_4 · Cited by 1 · see citing works

Role of Dietary Fat in Ultraviolet Light–Induced Carcinogenic Expression

Black, H. S. (2014) · Journal of Integrative Oncology · doi:10.4172/2329-6771.1000e107 · Cited by 1 · see citing works

Nutraceuticals for Skin Health

Yendapally, R. (2009) · CRC Press eBooks · doi:10.1201/9781420082227-c17 · Cited by 1 · see citing works

Oral Naturally Derived Agents as an Adjuvant Photoprotection after Dermatologic Surgery

Juntongjin, P., & Chanyasak, C. (2018) · InTech eBooks · doi:10.5772/intechopen.71750 · Cited by 1 · see citing works

Comparative Assessment of Nutraceuticals for Supporting Skin Health

Streker, M., Proksch, E., Kattenstroth, J.-C., Pöeggeler, B., & Lemmnitz, G. (2025) · Nutraceuticals · doi:10.3390/nutraceuticals5020013 · Cited by 2 · see citing works

Mediterranean Diet and Skin Health

Primavesi, L., Piantanida, M., & Pravettoni, V. (2012) · Humana Press eBooks · doi:10.1007/978-1-62703-167-7_1 · Cited by 1 · see citing works

Estrés oxidativo, carcinogénesis cutánea por radiación solar y quimioprotección con polifenoles

Landaeta, K. V., & Piombo, M. E. (2012) · Piel · doi:10.1016/j.piel.2011.11.015 · Cited by 1 · see citing works

An examination of the bioactive lipids involved in skin cell inflammation and in response to ultraviolet radiation. Effect of n-3 polyunsaturated fatty acid supplementation on red blood cell and human dermal fatty acid and production of eicosanoids by HaCaT keratinocytes and 46BR.1N fibroblasts following exposure to UVR.

Al‐Aasswad, N. M. I. (2013) · Bradford Scholars (University of Bradford)

Influence of Eicosapentaenoic Acid, an Omega‐3 Fatty Acid, on Ultraviolet‐B Generation of Prostaglandin‐E2 and Proinflammatory Cytokines Interleukin‐1β, Tumor Necrosis Factor‐α, Interleukin‐6 and Interleukin‐8 in Human Skin In Vivo¶

Shahbakhti, H., Watson, R. E. B., Azurdia, R. M., Ferreira, C. Z., Garmyn, M., & Rhodes, L. E. (2004) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2004.tb00076.x · Cited by 13 · see citing works

Influence of Eicosapentaenoic Acid, an Omega-3 Fatty Acid, on UVB-generation of PGE2and Pro-inflammatory Cytokines IL-1β, TNF-α, IL-6 and IL-8 in Human Skin in vivo

Shahbakhti, H., Watson, R. E. B., Azurdia, R. M., Ferreira, C. Z., Garmyn, M., & Rhodes, L. E. (2004) · Photochemistry and Photobiology · doi:10.1562/2004-01-27-ra-066 · Cited by 14 · see citing works

Protecting against skin cancer promotion : a clinical study to assess the effect of omega 3 fatty acid supplementation on photoimmunosuppression

Roshdy, K. (2012) · [Thesis]. Manchester, UK: The University of Manchester; 2012.

M.Azurdia2, Ralf M.W.Moison3, Marie-Jose

Rhodes, L. E., Shahbakhti, H., Steenwinkel, S. T., Homburg, M. I., Dean, M. P., Mcardle, F., Van, G. M. J. B., Epe, B., & Vink, A. A. (2014)