Simulated public speaking as a model of clinical anxiety
Abstract
Normal male volunteers took single acute doses of either diazepam or placebo under double-blind conditions in three simulated public speaking experiments. Measures of palmar sweating and subjective anxiety showed that anticipation of speaking in public increased anxiety relative to baseline and prestress conditions, and performance of public speaking further increased anxiety. A dose-related anxiolytic effect of diazepam on subjective anxiety supported the model's clinical relevance. Moreover, the intensity of the subject's public speaking phobia predicted both degree of prestress anxiety relief from 10 mg diazepam and overall anxiety level, regardless of medication, throughout the experimental session. A measure of traditionalism predicted placebo and 5 mg diazepam response during prestress: As in previous clinical trials, high traditionalism scorers reported more relief from placebo, whereas low scorers showed more relief from diazepam.
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The SPST used was the same as used by McNair et al (1982) with some modifications.
“The SPST was the same as used by McNair et al (1982) with some modifications (Hallak et al, 2010).”
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- Authors
- McNair, D. M., Frankenthaler, L. M., Czerlinsky, T., White, T. W., Sasson, S., & Fisher, S.
- Affiliations
- Boston University (US)
- University of Wisconsin–Stout (US)
- The University of Texas Medical Branch at Galveston (US)
- Venue
- Psychopharmacology
- Published
- 1982-05
- Volume
- 77
- Issue
- 1
- Pages
- 7-10
- ISSN
- 0033-3158 (ISSN-L)
- 1432-2072
- OpenAlex
- W2002924011
- Cited by
- 140
- References
- 0
- Citations by year
- 2026: 1 · 2024: 3 · 2023: 2 · 2022: 5 · 2021: 1 · 2020: 4 · 2019: 2 · 2018: 4 · 2017: 4 · 2016: 2 · 2014: 2 · 2013: 9 · 2012: 4
- FWCI
- 2.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Psychopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Pain Management and Placebo Effect
- Social Sciences › Psychology › Social Psychology › Communication in Education and Healthcare
- Keywords
- clinical anxiety, diazepam, anxiolytic effects, palmar sweating, subjective anxiety, placebo response, traditionalism
- MeSH terms
- Adolescent, Adult, Anxiety, Diazepam, Dose-Response Relationship, Drug, Humans, Male, Models, Psychological, Personality, Speech, Stress, Psychological, Sweating, Anti-Anxiety Agents
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