Cited by 96Attention Deficit Hyperactivity DisorderStress Responses and CortisolAdrenal Hormones and Disorders

Hypothalamic-pituitary-adrenal axis function in children with attention-deficit hyperactivity disorder

Kaneko, Motohisa, Hoshino, Yoshihiko, Hashimoto, Shinichi, Okano, Takaaki, Kumashiro, Hisashi·1993·Journal of Autism and Developmental Disorders

Abstract

Examined hypothalamic-pituitary-adrenal axis (HPA axis) function in 30 children with attention-deficit hyperactivity disorder (ADHD) by measuring the diurnal variation and response to the dexamethasone suppression test (DST) of saliva cortisol. Normal diurnal saliva cortisol rhythm was found in only 43.3% of the ADHD children. DST showed suppression in 46.7% of the ADHD children. An abnormal diurnal rhythm and nonsuppression to the DST were more frequent in the severely hyperactive group than in the mildly were more frequent in the severely hyperactive group than in the mildly hyperactive group of children with ADHD. These results suggest abnormalities in HPA axis function in some children with ADHD, especially those exhibiting severe hyperactivity.

Integrity signals

Registry

Crossref · 10.1007/bf01066418

Cites

25 of 25 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Kaneko, M., Hoshino, Y., Hashimoto, S., Okano, T., & Kumashiro, H.
Affiliations
Fukushima Medical University (JP)
Venue
Journal of Autism and Developmental Disorders
Published
1993-03
Volume
23
Issue
1
Pages
59-65
ISSN
  • 0162-3257 (ISSN-L)
  • 1573-3432
OpenAlex
W2014980780
Cited by
96
References
25
Citations by year
2025: 4 · 2024: 3 · 2022: 4 · 2021: 5 · 2020: 3 · 2019: 1 · 2018: 3 · 2017: 8 · 2016: 3 · 2015: 4 · 2014: 2 · 2013: 4 · 2012: 9
FWCI
0.00
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Autism and Developmental Disorders (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
  • Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Keywords
attention deficit hyperactivity disorder, hypothalamic-pituitary-adrenal axis, diurnal cortisol rhythm, salivary cortisol, dexamethasone suppression test, children
MeSH terms
Attention Deficit Disorder with Hyperactivity, Autistic Disorder, Brain, Child, Circadian Rhythm, Electroencephalography, Female, Humans, Hydrocortisone, Hypothalamo-Hypophyseal System, Intelligence, Male, Pituitary-Adrenal System, Psychiatric Status Rating Scales, Saliva

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review