The DOI matches its Crossref record; 72 of the 72 references it cites were found in a registry or an index.
Ion efflux systems involved in bacterial metal resistances
Open accessAbstract
Studying metal ion resistance gives us important insights into environmental processes and provides an understanding of basic living processes. This review concentrates on bacterial efflux systems for inorganic metal cations and anions, which have generally been found as resistance systems from bacteria isolated from metal-polluted environments. The protein products of the genes involved are sometimes prototypes of new families of proteins or of important new branches of known families. Sometimes, a group of related proteins (and presumedly the underlying physiological function) has still to be defined. For example, the efflux of the inorganic metal anion arsenite is mediated by a membrane protein which functions alone in Gram-positive bacteria, but which requires an additional ATPase subunit in some Gram-negative bacteria. Resistance to Cd2+ and Zn2+ in Gram-positive bacteria is the result of a P-type efflux ATPase which is related to the copper transport P-type ATPases of bacteria and humans (defective in the human hereditary diseases Menkes' syndrome and Wilson's disease). In contrast, resistance to Zn2+, Ni2+, Co2+ and Cd2+ in Gram-negative bacteria is based on the action of proton-cation antiporters, members of a newly-recognized protein family that has been implicated in diverse functions such as metal resistance/nodulation of legumes/cell division (therefore, the family is called RND). Another new protein family, named CDF for 'cation diffusion facilitator' has as prototype the protein CzcD, which is a regulatory component of a cobalt-zinc-cadmium resistance determinant in the Gram-negative bacterium Alcaligenes eutrophus. A family for the ChrA chromate resistance system in Gram-negative bacteria has still to be defined.
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Cites
The Wilson disease gene is a putative copper transporting P–type ATPase similar to the Menkes gene
Bull, P. C., Thomas, G. R., Rommens, J. M., Forbes, J. R., & Cox, D. W. (1993) · Nature Genetics · doi:10.1038/ng1293-327 · Cited by 1,948
Vulpe, C., Levinson, B., Whitney, S., Packman, S., & Gitschier, J. (1993) · Nature Genetics · doi:10.1038/ng0193-7 · Cited by 1,418
A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport
Marger, M. D., & Saier, M. H. (1993) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(93)90081-w · Cited by 948
Mergeay, M., Nies, D., Schlegel, H. G., Gerits, J., Charles, P., & Van Gijsegem, F. (1985) · Journal of Bacteriology · doi:10.1128/jb.162.1.328-334.1985 · Cited by 802
Self-citationChelly, J., Tümer, Z., Tønnesen, T., Petterson, A., Ishikawa-Brush, Y., Tommerup, N., Horn, N., & Monaco, A. P. (1993) · Nature Genetics · doi:10.1038/ng0193-14 · Cited by 726
Isolation of a partial candidate gene for Menkes disease by positional cloning
Mercer, J. F. B., Livingston, J., Hall, B., Paynter, J. A., Begy, C., Chandrasekharappa, S., Lockhart, P., Grimes, A., Bhave, M., Siemieniak, D., et al. (1993) · Nature Genetics · doi:10.1038/ng0193-20 · Cited by 696
Poole, K., Krebes, K., McNally, C., & Neshat, S. (1993) · Journal of Bacteriology · doi:10.1128/jb.175.22.7363-7372.1993 · Cited by 688
ABC transporters: bacterial exporters
Fath, M. J., & Kolter, R. (1993) · Microbiological Reviews · doi:10.1128/mmbr.57.4.995-1017.1993 · Cited by 679
High specificity of a phosphate transport protein determined by hydrogen bonds
Luecke, H., & Quiocho, F. A. (1990) · Nature · doi:10.1038/347402a0 · Cited by 537
Molecular cloning and characterization of acrA and acrE genes of Escherichia coli
Ma, D., Cook, D. N., Alberti, M., Pon, N. G., Nikaido, H., & Hearst, J. E. (1993) · Journal of Bacteriology · doi:10.1128/jb.175.19.6299-6313.1993 · Cited by 466
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Antiseptics and Disinfectants: Activity, Action, and Resistance
McDonnell, G., & Russell, A. D. (1999) · Clinical Microbiology Reviews · doi:10.1128/cmr.12.1.147 · Cited by 4,780
Metals, minerals and microbes: geomicrobiology and bioremediation
Gadd, G. M. (2010) · Microbiology · doi:10.1099/mic.0.037143-0 · Cited by 2,013
Microbial Resistance to Metals in the Environment
Bruins, M. R., Kapil, S., & Oehme, F. W. (2000) · Ecotoxicology and Environmental Safety · doi:10.1006/eesa.1999.1860 · Cited by 1,445
Bacterial silver resistance: molecular biology and uses and misuses of silver compounds
Silver, S. (2003) · FEMS Microbiology Reviews · doi:10.1016/s0168-6445(03)00047-0 · Cited by 1,312
Self-citationPhylogenetic Relationships within Cation Transporter Families of Arabidopsis
Mäser, P., Thomine, S., Schroeder, J. I., Ward, J. M., Hirschi, K., Sze, H., Talke, I. N., Amtmann, A., Maathuis, F. J. M., Sanders, D., et al. (2001) · Plant Physiology · doi:10.1104/pp.126.4.1646 · Cited by 1,257
Seiler, C., & Berendonk, T. U. (2012) · Frontiers in Microbiology · doi:10.3389/fmicb.2012.00399 · Cited by 1,018
Zinc transporters and the cellular trafficking of zinc
Eide, D. J. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2006.03.005 · Cited by 874
Heavy Metal Pollution from Gold Mines: Environmental Effects and Bacterial Strategies for Resistance
Fashola, M., Ngole-Jeme, V., & Babalola, O. (2016) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph13111047 · Cited by 786
Bacterial resistances to toxic metal ions - a review
Silver, S. (1996) · Gene · doi:10.1016/s0378-1119(96)00323-x · Cited by 592
Self-citationArsenic geochemistry and health
DUKER, A., CARRANZA, E., & HALE, M. (2005) · Environment International · doi:10.1016/j.envint.2004.10.020 · Cited by 585
Ma, Y., Oliveira, R. S., Freitas, H., & Zhang, C. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2016.00918 · Cited by 553
Kushwaha, A., Hans, N., Kumar, S., & Rani, R. (2018) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2017.09.049 · Cited by 543
Shamim, S. (2018) · Biosorption · doi:10.5772/intechopen.72099 · Cited by 538
Eukaryotic zinc transporters and their regulation
Gaither, L. A., & Eide, D. J. (2001) · Biometals · doi:10.1023/a:1012988914300 · Cited by 521
Molecular basis for resistance to silver cations in Salmonella
Gupta, A., Matsui, K., Lo, J.-F., & Silver, S. (1999) · Nature Medicine · doi:10.1038/5545 · Cited by 473
Self-citationMontanini, B., Blaudez, D., Jeandroz, S., Sanders, D., & Chalot, M. (2007) · BMC Genomics · doi:10.1186/1471-2164-8-107 · Cited by 420
Engineering Deinococcus radiodurans for metal remediation in radioactive mixed waste environments
Brim, H., McFarlan, S. C., Fredrickson, J. K., Minton, K. W., Zhai, M., Wackett, L. P., & Daly, M. J. (2000) · Nature Biotechnology · doi:10.1038/71986 · Cited by 400
Bacterial resistance to disinfectants: present knowledge and future problems
Russell, A. D. (1999) · Journal of Hospital Infection · doi:10.1016/s0195-6701(99)90066-x · Cited by 396
Trace element behaviour at the root–soil interface: Implications in phytoremediation
Kidd, P., Barceló, J., Bernal, M. P., Navari-Izzo, F., Poschenrieder, C., Shilev, S., Clemente, R., & Monterroso, C. (2009) · Environmental and Experimental Botany · doi:10.1016/j.envexpbot.2009.06.013 · Cited by 395
Impact of metals on the biodegradation of organic pollutants.
Sandrin, T. R., & Maier, R. M. (2003) · Environmental Health Perspectives · doi:10.1289/ehp.5840 · Cited by 386
Heavy Metal Pollution: Source, Impact, and Remedies
Mohammed, A. S., Kapri, A., & Goel, R. (2011) · Environmental Pollution · doi:10.1007/978-94-007-1914-9_1 · Cited by 355
Janssen, P. J., Van Houdt, R., Moors, H., Monsieurs, P., Morin, N., Michaux, A., Benotmane, M. A., Leys, N., Vallaeys, T., Lapidus, A., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010433 · Cited by 332
Paulsen, I. T., Sliwinski, M. K., & Saier, M. H. (1998) · Journal of Molecular Biology · doi:10.1006/jmbi.1998.1609 · Cited by 295
Naik, M. M., & Dubey, S. K. (2013) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2013.09.039 · Cited by 272
ZupT Is a Zn(II) Uptake System in Escherichia coli
Grass, G., Wong, M. D., Rosen, B. P., Smith, R. L., & Rensing, C. (2002) · Journal of Bacteriology · doi:10.1128/jb.184.3.864-866.2002 · Cited by 197
Suzuki, T., Ishihara, K., Migaki, H., Ishihara, K., Nagao, M., Yamaguchi-Iwai, Y., & Kambe, T. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m506902200 · Cited by 168
Hassan, M.-E.-T., van der Lelie, D., Springael, D., Römling, U., Ahmed, N., & Mergeay, M. (1999) · Gene · doi:10.1016/s0378-1119(99)00349-2 · Cited by 165
An Antimicrobial Role for Zinc in Innate Immune Defense Against Group A Streptococcus
Ong, C.-L. Y., Gillen, C. M., Barnett, T. C., Walker, M. J., & McEwan, A. G. (2014) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiu053 · Cited by 124
Pathogenic adaptations to host-derived antibacterial copper
Chaturvedi, K. S., & Henderson, J. P. (2014) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2014.00003 · Cited by 134
Turner, A. G., Ong, C.-L. Y., Gillen, C. M., Davies, M. R., West, N. P., McEwan, A. G., & Walker, M. J. (2015) · mBio · doi:10.1128/mbio.00278-15 · Cited by 93
Metal bioavailability and the soil microbiome
Sullivan, T. S., & Gadd, G. M. (2019) · Advances in Agronomy · doi:10.1016/bs.agron.2019.01.004 · Cited by 50
Transcriptome analysis of probiotic Lactobacillus casei Zhang during fermentation in soymilk
Wang, J.-C., Zhang, W.-Y., Zhong, Z., Wei, A.-B., Bao, Q.-H., Zhang, Y., Sun, T.-S., Postnikoff, A., Meng, H., & Zhang, H.-P. (2012) · Journal of Industrial Microbiology and Biotechnology · doi:10.1007/s10295-011-1015-7 · Cited by 27
Kaur, H., Katyal, P., Natt, S. K., Vikal, Y., & Chandel, S. (2025) · Indian Journal of Microbiology · doi:10.1007/s12088-024-01362-y · Cited by 4
Metadata
- Authors
- Nies, D. H., & Silver, S.
- Venue
- Journal of Industrial Microbiology
- Publisher
- Oxford University Press (OUP)
- Published
- 1995-02
- Volume
- 14
- Issue
- 2
- Pages
- 186-199
- ISSN
- 1367-5435 (ISSN-L)
- 0169-4146
- 1476-5535
- OpenAlex
- W2007266049
- Cited by
- 548
- References
- 72
- FWCI
- 6.29
- Type
- journal article
- Language
- en
- Open access
- bronze
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