On the constancy of the evolutionary rate of cistrons
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Tomoko Ohta provided an important extension of the neutral theory by recognizing the crucial role of effective population size in the influence of selection.
“Tomoko Ohta 22-24 provided an important extension of the neutral theory by recognizing the crucial role of effective population size in the influence of selection.”
From The modern molecular clock (2003) · cites this paper as [22]
A mutation would be effectively neutral if |s| < 1/4N_e, where N_e is the effective population size.
“So, a mutation would be effectively neutral if |s| < 1/4N e , where N e is the effective population size.”
From The modern molecular clock (2003) · cites this paper as [22]
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- Authors
- Ohta, T., & Kimura, M.
- Affiliations
- National Institute of Genetics (JP)
- Venue
- Journal of Molecular Evolution
- Published
- 1971-03
- Volume
- 1
- Issue
- 1
- Pages
- 18-25
- ISSN
- 0022-2844 (ISSN-L)
- 1432-1432
- OpenAlex
- W2083365573
- Cited by
- 322
- References
- 22
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 6 · 2023: 7 · 2022: 2 · 2021: 7 · 2020: 7 · 2019: 3 · 2018: 10 · 2017: 3 · 2016: 2 · 2015: 6 · 2014: 22 · 2013: 6 · 2012: 4
- FWCI
- 5.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Molecular Evolution (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Physical Sciences › Earth and Planetary Sciences › Paleontology › Evolution and Paleontology Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Keywords
- amino acid substitution rates, hemoglobin, cytochrome c, fixation probability, mutation rate, effective population size, generation time, adaptive substitutions, vertebrate evolution
- MeSH terms
- Amino Acid Sequence, Animals, Cytochrome c Group, Biological Evolution, Genes, Genetic Code, Hemoglobins, Humans, Models, Biological, Mutation
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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