Amphiphilic components of the murchison carbonaceous chondrite: Surface properties and membrane formation
Abstract
We have investigated physicochemical properties of amphiphilic compounds in carbonaceous meteorites. The primary aim was to determine whether such materials represent plausible sources of lipid-like compounds that could have been involved as membrane components in primitive cells. Samples of the Murchison CM2 chondrite were extracted with chloroform-methanol, and the chloroform-soluble material was separated by two-dimensional thin layer chromatography. Fluorescence, iodine stains and charring were used to identify major components on the plates. These were then scraped and eluted as specific fractions which were investigated by fluorescence and absorption spectra, surface chemical methods, gas chromatography-mass spectrometry, and electron microscopy. Fraction 5 was strongly fluorescent, and contained pyrene and fluoranthene, the major polycyclic aromatic hydrocarbons of the Murchison chondrite. This fraction was also present in extracts from the Murray and Mighei CM2 chondrites. Fraction 3 was surface active, forming apparent monomolecular films at air-water interfaces. Surface force measurements suggested that fraction 3 contained acidic groups. Fraction 1 was also surface active, and certain components could self-assemble into membranous vesicles which encapsulated polar solutes. The observations reported here demonstrate that organic compounds plausibly available on the primitive Earth through meteoritic infall are surface active, and have the ability to self-assemble into membranes.
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Amphiphilic compounds are present in carbonaceous meteorites and can assemble into membranous vesicles.
“Amphiphilic compounds are present in carbonaceous meteorites and can assemble into membranous vesicles (Deamer, 1985; Deamer and Pashley, 1989; Naraoka et al., 1999; Deamer et al. 2002; Deamer and Dworkin, 2005).”
From The Hot Spring Hypothesis for an Origin of Life (2020) · cites this paper as Deamer and Pashley, 1989
Amphiphilic molecules collected from the Murchison meteorite spontaneously form vesicles when placed in aqueous solution.
“Amphiphilic molecules collected from the Murchison meteorite spontaneously form vesicles when placed in aqueous solution (Deamer and Pashley, 1989).”
From The Astrobiology Primer v2.0 (2016) · cites this paper as Deamer and Pashley, 1989
Cites
Physical chemistry of surfaces
Adamson, A. W., & Gast, A. P. (1998) · Choice Reviews Online · doi:10.5860/choice.35-4499 · Cited by 11,684 · see citing works
Physical Chemistry of Surfaces
ADAMSON, A. W., & Klerer, J. (1977) · Journal of The Electrochemical Society · doi:10.1149/1.2133374 · Cited by 2,990 · see citing works
Israelachvili, J. N., & Adams, G. E. (1978) · Journal of the Chemical Society, Faraday Transactions 1: Physical Chemistry in Condensed Phases · doi:10.1039/f19787400975 · Cited by 1,812 · see citing works
Topics in Current Chemistry: Inorganic Biochemistry
(1976) · Topics in Current Chemistry · doi:10.1007/bfb0045697 · Cited by 1,044 · see citing works
Evidence for Extraterrestrial Amino-acids and Hydrocarbons in the Murchison Meteorite
Kvenvolden, K. A., Lawless, J. G., Pering, K. L., Peterson, E., Flores, J. J. A., Ponnamperuma, C., Kaplan, I. R., & MOORE, C. B. (1970) · Nature · doi:10.1038/228923a0 · Cited by 867 · see citing works
Aarseth, S. J. (1986) · Endeavour · doi:10.1016/0160-9327(86)90016-5 · Cited by 749 · see citing works
Attractive Forces Between Uncharged Hydrophobic Surfaces: Direct Measurements in Aqueous Solution
Pashley, R. M., McGuiggan, P. M., Ninham, B. W., & Evans, D. F. (1985) · Science · doi:10.1126/science.4035349 · Cited by 493 · see citing works
Self-citationChan, D. Y. C., Pashley, R. M., & White, L. R. (1980) · Journal of Colloid and Interface Science · doi:10.1016/0021-9797(80)90445-2 · Cited by 353 · see citing works
Self-citationPick, U. (1981) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(81)90358-1 · Cited by 349 · see citing works
Boundary structures are formed by organic-components of the Murchison carbonaceous chondrite
Deamer, D. W. (1985) · Nature · doi:10.1038/317792a0 · Cited by 270 · see citing works
Self-citationMolecules in the galactic environment
Gordon, M. A., & Snyder, L. E. (1973) · Cited by 265 · see citing works
Organic compounds in meteorites and their origins
Hayatsu, R., & Anders, E. (1981) · Topics in current chemistry · doi:10.1007/3-540-10920-x_13 · Cited by 263 · see citing works
Amino Acid Analyses of the Murchison, Murray, and Allende Carbonaceous Chondrites
Cronin, J. R., & MOORE, C. B. (1971) · Science · doi:10.1126/science.172.3990.1327 · Cited by 240 · see citing works
Organic Compounds in Meteorites
Anders, E., Hayatsu, R., & Studier, M. H. (1973) · Science · doi:10.1126/science.182.4114.781 · Cited by 230 · see citing works
Allamandola, L. J., Sandford, S. A., & Wopenka, B. (1987) · Science · doi:10.1126/science.237.4810.56 · Cited by 219 · see citing works
Amino-acids, Aliphatic and Aromatic Hydrocarbons in the Murchison Meteorite
Oro, J. A., de Gibert, J. M., Lichtenstein, H. A., Wikström, S. A., & Flory, D. A. (1971) · Nature · doi:10.1038/230105a0 · Cited by 198 · see citing works
Hagen, W., Allamandola, L. J., & Greenberg, J. M. (1979) · Astrophysics and Space Science · doi:10.1007/bf00643502 · Cited by 185 · see citing works
Studier, M. H., Hayatsu, R., & Anders, E. (1972) · Geochimica et Cosmochimica Acta · doi:10.1016/0016-7037(72)90006-3 · Cited by 174 · see citing works
Quantification of monocarboxylic acids in the Murchison carbonaceous meteorite
Lawless, J. G., & Yuen, G. U. (1979) · Nature · doi:10.1038/282396a0 · Cited by 173 · see citing works
Endogenous Carbon in Carbonaceous Meteorites
Smith, J. W., & Kaplan, I. R. (1970) · Science · doi:10.1126/science.167.3923.1367 · Cited by 152 · see citing works
Polycyclic aromatic hydrocarbons in the Murchison meteorite
Basile, B., Middleditch, B. S., & Oró, J. (1984) · Organic Geochemistry · doi:10.1016/0146-6380(84)90008-1 · Cited by 127 · see citing works
Kerridge, J. F. (1983) · Earth and Planetary Science Letters · doi:10.1016/0012-821x(83)90203-0 · Cited by 114 · see citing works
Relic interstellar grains in Murchison meteorite
Yang, J., & Epstein, S. (1984) · Nature · doi:10.1038/311544a0 · Cited by 92 · see citing works
The properties and theory of genesis of the carbonaceous complex within the cold bokevelt meteorite
Mueller, G. P. (1953) · Geochimica et Cosmochimica Acta · doi:10.1016/0016-7037(53)90061-1 · Cited by 90 · see citing works
d’Hendecourt, L., Allamandola, L. J., Grim, R. J. A., & Greenberg, J. M. (1986) · Leiden Repository (Leiden University) · Cited by 69 · see citing works
The cometary connection with prebiotic chemistry
Delsemme, A. H. (1984) · Origins of Life · doi:10.1007/bf00933639 · Cited by 51 · see citing works
A note on Pope's cohort analysis
Siddeek, M. S. M. (1982) · ICES Journal of Marine Science · doi:10.1093/icesjms/40.3.209 · Cited by 8 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Prebiotic chemistry and the origin of the RNA world.
Leslie E., O. (2004) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409230490460765 · Cited by 1,124 · see citing works
Prebiotic Systems Chemistry: New Perspectives for the Origins of Life
Ruiz-Mirazo, K., Briones, C., & de la Escosura, A. (2014) · Chemical Reviews · doi:10.1021/cr2004844 · Cited by 930 · see citing works
Physical properties of the fluid lipid-bilayer component of cell membranes: a perspective
Bloom, M., Evans, E. A., & Mouritsen, O. G. (1991) · Quarterly Reviews of Biophysics · doi:10.1017/s0033583500003735 · Cited by 872 · see citing works
Experimental Models of Primitive Cellular Compartments: Encapsulation, Growth, and Division
Hanczyc, M. M., Fujikawa, S. M., & Szostak, J. W. (2003) · Science · doi:10.1126/science.1089904 · Cited by 848 · see citing works
Organic compounds in carbonaceous meteorites
Sephton, M. A. (2002) · Natural Product Reports · doi:10.1039/b103775g · Cited by 704 · see citing works
2° Surfactants and their applications
Schramm, L. L., Stasiuk, E. N., & Marangoni, D. G. (2003) · Annu. Rep. Prog. Chem., Sect. C: Phys. Chem. · doi:10.1039/b208499f · Cited by 664 · see citing works
Peptide–nucleotide microdroplets as a step towards a membrane-free protocell model
Koga, S., Williams, D. S., Perriman, A. W., & Mann, S. (2011) · Nature Chemistry · doi:10.1038/nchem.1110 · Cited by 651 · see citing works
Segré, D., Ben-Eli, D., Deamer, D. W., & Lancet, D. (2001) · Origins of life and evolution of the biosphere · doi:10.1023/a:1006746807104 · Cited by 620 · see citing works
Self-citationOrganic molecules in the Sheepbed Mudstone, Gale Crater, Mars
Freissinet, C., Glavin, D. P., Mahaffy, P. R., Miller, K. E., Eigenbrode, J. L., Summons, R. E., Brunner, A. E., Buch, A., Szopa, C., Archer, P. D., et al. (2015) · Journal of Geophysical Research: Planets · doi:10.1002/2014je004737 · Cited by 516 · see citing works
Coupled Growth and Division of Model Protocell Membranes
Zhu, T. F., & Szostak, J. W. (2009) · Journal of the American Chemical Society · doi:10.1021/ja900919c · Cited by 496 · see citing works
The Hot Spring Hypothesis for an Origin of Life
Damer, B., & Deamer, D. (2020) · Astrobiology · doi:10.1089/ast.2019.2045 · Cited by 478 · see citing works
“Amphiphilic compounds are present in carbonaceous meteorites and can assemble into membranous vesicles (Deamer, 1985; Deamer and Pashley, 1989; Naraoka et al., 1999; Deamer et al. 2002; Deamer and Dworkin, 2005).”
BackgroundSelf-citationCompositional genomes: Prebiotic information transfer in mutually catalytic noncovalent assemblies
Segré, D., Ben-Eli, D., & Lancet, D. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.8.4112 · Cited by 398 · see citing works
The Influence of Organic Films at the Air−Aqueous Boundary on Atmospheric Processes
Donaldson, D. J., & Vaida, V. (2006) · Chemical Reviews · doi:10.1021/cr040367c · Cited by 390 · see citing works
Holm, N. G., & Charlou, J. L. (2001) · Earth and Planetary Science Letters · doi:10.1016/s0012-821x(01)00397-1 · Cited by 363 · see citing works
Apel, C. L., Deamer, D. W., & Mautner, M. N. (2002) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(01)00400-x · Cited by 350 · see citing works
Self-citationMineral surfaces, geochemical complexities, and the origins of life
Hazen, R. M., & Sverjensky, D. A. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a002162 · Cited by 344 · see citing works
Membrane self‐assembly processes: Steps toward the first cellular life
Monnard, P., & Deamer, D. W. (2002) · The Anatomical Record · doi:10.1002/ar.10154 · Cited by 319 · see citing works
Self-citationDamer, B., & Deamer, D. (2015) · Life · doi:10.3390/life5010872 · Cited by 309 · see citing works
Self-citationThe first living systems: a bioenergetic perspective
Deamer, D. W. (1997) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.61.2.239-261.1997 · Cited by 305 · see citing works
Self-citationPhysical effects underlying the transition from primitive to modern cell membranes
Budin, I., & Szostak, J. W. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1100498108 · Cited by 289 · see citing works
Lipid vesicles as possible intermediates in the origin of life
Luisi, P. L., Walde, P., & Oberholzer, T. (1999) · Current Opinion in Colloid & Interface Science · doi:10.1016/s1359-0294(99)00012-6 · Cited by 287 · see citing works
Handbook of Surface and Colloid Chemistry
Birdi, K. S. (2008) · CRC Press eBooks · doi:10.1201/9781420007206 · Cited by 283 · see citing works
From self-assembled vesicles to protocells
Chen, I. A., & Walde, P. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a002170 · Cited by 256 · see citing works
Deamer, D., Dworkin, J. P., Sandford, S. A., Bernstein, M. P., & Allamandola, L. J. (2002) · Astrobiology · doi:10.1089/153110702762470482 · Cited by 270 · see citing works
Self-citationBridging Nonliving and Living Matter
Rasmussen, S., Chen, L., Nilsson, M., & Abe, S. (2003) · Artificial Life · doi:10.1162/106454603322392479 · Cited by 266 · see citing works
Schrum, J. P., Zhu, T. F., & Szostak, J. W. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a002212 · Cited by 255 · see citing works
A kinetic study of the growth of fatty acid vesicles
Chen, I. A., & Szostak, J. W. (2004) · Biophysical Journal · doi:10.1529/biophysj.104.039875 · Cited by 251 · see citing works
Self-assembling amphiphilic molecules: Synthesis in simulated interstellar/precometary ices
Dworkin, J. P., Deamer, D. W., Sandford, S. A., & Allamandola, L. J. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.3.815 · Cited by 244 · see citing works
Self-citationSandford, S. A., Nuevo, M., Bera, P. P., & Lee, T. J. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00560 · Cited by 227 · see citing works
Astrobiology: The Study of the Living Universe
Chyba, C. F., & Hand, K. P. (2005) · Annual Review of Astronomy and Astrophysics · doi:10.1146/annurev.astro.43.051804.102202 · Cited by 166 · see citing works
THE ORIGIN AND EARLY EVOLUTION OF LIFE ON EARTH
Oro, J., Miller, S. L., & Lazcano, A. (1990) · Annual Review of Earth and Planetary Sciences · doi:10.1146/annurev.ea.18.050190.001533 · Cited by 160 · see citing works
Hazen, R. M. (2006) · American Mineralogist · doi:10.2138/am.2006.2289 · Cited by 134 · see citing works
Self-assembly processes in the prebiotic environment
Deamer, D., Singaram, S., Rajamani, S., Kompanichenko, V., & Guggenheim, S. (2006) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2006.1905 · Cited by 133 · see citing works
Self-citationDomagal-Goldman, S. D., Wright, K. E., Domagal-Goldman, S. D., Wright, K. E., Adamala, K., Arina de la Rubia, L., Bond, J., Dartnell, L. R., Goldman, A. D., Lynch, K., et al. (2016) · Astrobiology · doi:10.1089/ast.2015.1460 · Cited by 136 · see citing works
“Amphiphilic molecules collected from the Murchison meteorite spontaneously form vesicles when placed in aqueous solution (Deamer and Pashley, 1989).”
Protocells: Milestones and Recent Advances
Gözen, İ., Köksal, E. S., Põldsalu, I., Xue, L., Spustová, K., Pedrueza‐Villalmanzo, E., Ryskulov, R., Meng, F., & Jesorka, A. (2022) · Small · doi:10.1002/smll.202106624 · Cited by 135 · see citing works
The Origin of Life in the Solar System: Current Issues
Chyba, C. F., & McDonald, G. D. (1995) · Annual Review of Earth and Planetary Sciences · doi:10.1146/annurev.ea.23.050195.001243 · Cited by 132 · see citing works
Membrane Transport in Primitive CellsPreprint
Mansy, S. S. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a002188 · Cited by 127 · see citing works
Oceanic protection of prebiotic organic compounds from UV radiation
Cleaves, H. J., & Miller, S. L. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.13.7260 · Cited by 125 · see citing works
Smith, J. V. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.7.3370 · Cited by 123 · see citing works
Lipids as Universal Biomarkers of Extraterrestrial Life
Georgiou, C. D., & Deamer, D. W. (2014) · Astrobiology · doi:10.1089/ast.2013.1134 · Cited by 120 · see citing works
Self-citationBonner, W. A. (1998) · Birkhäuser Basel eBooks · doi:10.1007/978-3-0348-8837-0_10 · Cited by 116 · see citing works
Bloom, M., & Mouritsen, O. G. (1988) · Canadian Journal of Chemistry · doi:10.1139/v88-123 · Cited by 118 · see citing works
Generation of oligonucleotides under hydrothermal conditions by non-enzymatic polymerization
DeGuzman, V., Vercoutere, W., Shenasa, H., & Deamer, D. (2014) · Journal of Molecular Evolution · doi:10.1007/s00239-014-9623-2 · Cited by 99 · see citing works
Self-citationStability of model membranes in extreme environments
Namani, T., & Deamer, D. W. (2008) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-008-9131-8 · Cited by 97 · see citing works
Self-citationOn the Origin of Primitive Cells: From Nutrient Intake to Elongation of Encapsulated Nucleotides
Meierhenrich, U. J., Filippi, J., Meinert, C., Vierling, P., & Dworkin, J. P. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.200905465 · Cited by 94 · see citing works
Chemistry and Physics of Primitive Membranes
Deamer, D. W., & Dworkin, J. P. (2005) · Springer eBooks · doi:10.1007/b136806 · Cited by 92 · see citing works
Self-citationNutrient Uptake by Protocells: A Liposome Model System
Monnard, P., & Deamer, D. W. (2001) · Origins of Life and Evolution of Biospheres · doi:10.1023/a:1006769503968 · Cited by 92 · see citing works
Self-citationClays and the Origin of Life: The Experiments
Kloprogge, J. T., & Hartman, H. (2022) · Life · doi:10.3390/life12020259 · Cited by 66 · see citing works
Self-reproducing catalytic micelles as nanoscopic protocell precursors
Kahana, A., & Lancet, D. (2021) · Nature Reviews Chemistry · doi:10.1038/s41570-021-00329-7 · Cited by 80 · see citing works
Polycyclic aromatic hydrocarbons: Primitive pigment systems in the prebiotic environment
Deamer, D. W. (1992) · Advances in Space Research · doi:10.1016/0273-1177(92)90171-s · Cited by 81 · see citing works
Self-citationPreparation of vesicles from nonphospholipid amphiphiles
Monnard, P.-A., & Deamer, D. W. (2003) · Methods in Enzymology · doi:10.1016/s0076-6879(03)72008-4 · Cited by 79 · see citing works
Self-citationA Possible Route to Prebiotic Vesicle Reproduction
Luisi, P. L., Stano, P., Rasi, S., & Mavelli, F. (2004) · Artificial Life · doi:10.1162/1064546041255601 · Cited by 77 · see citing works
Chance and necessity do not explain the origin of life
Trevors, J. T., & Abel, D. L. (2004) · Cell Biology International · doi:10.1016/j.cellbi.2004.06.006 · Cited by 74 · see citing works
Ocean–Atmosphere Interactions in the Emergence of Complexity in Simple Chemical Systems
Griffith, E. C., Tuck, A. F., & Vaida, V. (2012) · Accounts of Chemical Research · doi:10.1021/ar300027q · Cited by 73 · see citing works
Polycyclic Aromatic Hydrocarbons as Plausible Prebiotic Membrane Components
Groen, J., Deamer, D. W., Kros, A., & Ehrenfreund, P. (2012) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-012-9292-3 · Cited by 72 · see citing works
Self-citationNuevo, M., Cooper, G., & Sandford, S. A. (2018) · Nature Communications · doi:10.1038/s41467-018-07693-x · Cited by 72 · see citing works
Prebiological Membranes and Their Role in the Emergence of Early Cellular Life
Sarkar, S., Das, S., Dagar, S., Joshi, M. P., Mungi, C. V., Sawant, A. A., Patki, G. M., & Rajamani, S. (2020) · The Journal of Membrane Biology · doi:10.1007/s00232-020-00155-w · Cited by 70 · see citing works
COHN, C., Borda, M. J., & Schoonen, M. A. A. (2004) · Earth and Planetary Science Letters · doi:10.1016/j.epsl.2004.07.007 · Cited by 68 · see citing works
Dávila, A. F., & McKay, C. P. (2014) · Astrobiology · doi:10.1089/ast.2014.1150 · Cited by 64 · see citing works
Metabolism and motility in prebiotic structures
Hanczyc, M. M. (2011) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2011.0141 · Cited by 64 · see citing works
A Fission-Fusion Origin for Life
Norris, V., & Raine, D. J. (1998) · Origins of life and evolution of the biosphere · doi:10.1023/a:1006568226145 · Cited by 63 · see citing works
Mautner, M. N., Leonard, R. L., & Deamer, D. W. (1995) · Planetary and Space Science · doi:10.1016/0032-0633(94)00205-6 · Cited by 59 · see citing works
Self-citationDynamics of pattern formation in biomimetic systems
Rossi, F., Ristori, S., Rustici, M., Marchettini, N., & Tiezzi, E. (2008) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2008.08.026 · Cited by 56 · see citing works
The Origin and Early Evolution of Membrane Channels
Pohorille, A., Schweighofer, K. J., & Wilson, M. A. (2005) · Astrobiology · doi:10.1089/ast.2005.5.1 · Cited by 59 · see citing works
Prebiological evolution and the physics of the origin of life
Delaye, L., & Lazcano, A. (2005) · Physics of Life Reviews · doi:10.1016/j.plrev.2004.12.002 · Cited by 56 · see citing works
Model Protocells from Single-Chain Lipids
Mansy, S. S. (2009) · International Journal of Molecular Sciences · doi:10.3390/ijms10030835 · Cited by 54 · see citing works
Liposomes Came First: The Early History of Liposomology
Weissig, V. (2016) · Methods in molecular biology · doi:10.1007/978-1-4939-6591-5_1 · Cited by 54 · see citing works
Prebiotic Protocell Model Based on Dynamic Protein Membranes Accommodating Anabolic Reactions
Schreiber, A. W., Huber, M. C., & Schiller, S. M. (2019) · Langmuir · doi:10.1021/acs.langmuir.9b00445 · Cited by 53 · see citing works
From Vesicles to Protocells: The Roles of Amphiphilic Molecules
Sakuma, Y., & Imai, M. (2015) · Life · doi:10.3390/life5010651 · Cited by 52 · see citing works
Cell evolution and the problem of membrane topology
Griffiths, G. W. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2287 · Cited by 52 · see citing works
Emergence of life: Physical chemistry changes the paradigm
Spitzer, J. J., Pielak, G. J., & Poolman, B. (2015) · Biology Direct · doi:10.1186/s13062-015-0060-y · Cited by 51 · see citing works
Chemical synthesis of lipids and the origin of life
Oro, J. A. (1995) · Journal of Biological Physics · doi:10.1007/bf00700430 · Cited by 49 · see citing works
Thermoeconomics: Beyond the Second Law
Corning, P. A. (2002) · Journal of Bioeconomics · doi:10.1023/a:1020633317271 · Cited by 48 · see citing works
Permeation of Membranes by Ribose and Its Diastereomers
Wei, C., & Pohorille, A. (2009) · Journal of the American Chemical Society · doi:10.1021/ja902531k · Cited by 46 · see citing works
Tuning ion channel mechanosensitivity by asymmetry of the transbilayer pressure profile
Martinac, B., Bavi, N., Ridone, P., Nikolaev, Y. A., Martinac, A. D., Nakayama, Y., Rohde, P. R., & Bavi, O. (2018) · Biophysical Reviews · doi:10.1007/s12551-018-0450-3 · Cited by 45 · see citing works
Helix insertion into bilayers and the evolution of membrane proteins
Renthal, R. D. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-009-0234-9 · Cited by 45 · see citing works
Catalysis and Prebiotic Synthesis
Ferris, J. P. (2005) · Reviews in Mineralogy and Geochemistry · doi:10.2138/rmg.2005.59.8 · Cited by 46 · see citing works
Pohorille, A., & Wilson, M. A. (1995) · Origins of Life and Evolution of the Biosphere · doi:10.1007/bf01581571 · Cited by 44 · see citing works
Chakrabarti, A. C., & Deamer, D. W. (1994) · Journal of Molecular Evolution · doi:10.1007/bf00178243 · Cited by 43 · see citing works
Self-citationAddendum: Origins of cellular life: Molecular foundations and new approaches
Ourisson, G., & Nakatani, Y. (1999) · Tetrahedron · doi:10.1016/s0040-4020(99)00116-7 · Cited by 43 · see citing works
Frank, P., Bonner, W. A., & Zare, R. N. (2000) · Wiley eBooks · doi:10.1002/9783527612949.ch11 · Cited by 43 · see citing works
Meteoritic abundances of fatty acids and potential reaction pathways in planetesimals
Lai, J., Pearce, B. K. D., Pudritz, R., & Lee, D. (2018) · Icarus (New York, N.Y. 1962) · doi:10.1016/j.icarus.2018.09.028 · Cited by 37 · see citing works
The Coevolution of Cellularity and Metabolism Following the Origin of Life
Takagi, Y. A., Nguyen, D. H., Wexler, T., & Goldman, A. D. (2020) · Journal of Molecular Evolution · doi:10.1007/s00239-020-09961-1 · Cited by 40 · see citing works
What is Life? Defining Life in the Context of Emergent Complexity
Weber, B. H. (2010) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-010-9203-4 · Cited by 40 · see citing works
Mineral–Lipid Interactions in the Origins of Life
Dalai, P., & Sahai, N. (2018) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2018.11.009 · Cited by 40 · see citing works
Hezave, A. Z., Dorostkar, S., Ayatollahi, S., Nabipour, M., & Hemmateenejad, B. (2013) · Journal of Dispersion Science and Technology · doi:10.1080/01932691.2013.844075 · Cited by 38 · see citing works
Lipid constituents of model protocell membranes
Wang, A., & Szostak, J. W. (2019) · Emerging Topics in Life Sciences · doi:10.1042/etls20190021 · Cited by 38 · see citing works
Thomas, J. A., & Rana, F. R. (2007) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-007-9065-6 · Cited by 38 · see citing works
MESOBIOTIC EMERGENCE: MOLECULAR AND ENSEMBLE COMPLEXITY IN EARLY EVOLUTION
SHENHAV, B., SEGRÈ, D., & LANCET, D. (2003) · Advances in Complex Systems · doi:10.1142/s0219525903000785 · Cited by 37 · see citing works
Organic Geochemistry of Meteorites
Sephton, M. A. (2013) · Elsevier eBooks · doi:10.1016/b978-0-08-095975-7.01002-0 · Cited by 36 · see citing works
Mass Spectrometry of Surfactant Aggregates
Ceraulo̊, L., Giorgi, G., Liveri, V. T., Bongiorno, D., Indelicato, S., Gaudio, F. D., & Indelicato, S. (2011) · European Journal of Mass Spectrometry · doi:10.1255/ejms.1158 · Cited by 36 · see citing works
Emergence of Life and Biological Selection from the Perspective of Complex Systems Dynamics
Weber, B. H. (1998) · Springer eBooks · doi:10.1007/978-94-017-1510-2_6 · Cited by 35 · see citing works
Fiore, M., Chieffo, C., Lopez, A., Fayolle, D., Ruiz, J., Soulère, L., Oger, P., Altamura, E., Popowycz, F., & Buchet, R. (2022) · Astrobiology · doi:10.1089/ast.2021.0059 · Cited by 34 · see citing works
Polymer Gard: Computer Simulation of Covalent Bond Formation in Reproducing Molecular Assemblies
Shenhav, B., Bar-Even, A., Kafri, R., & Lancet, D. (2005) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-005-5578-z · Cited by 33 · see citing works
Biogenesis as an evolutionary process
Morowitz, H. J., Deamer, D. W., & Smith, T. F. (1991) · Journal of Molecular Evolution · doi:10.1007/bf02100670 · Cited by 33 · see citing works
Self-citationThe emergence of patterning in lifes origin and evolution
Hazen, R. M. (2009) · The International Journal of Developmental Biology · doi:10.1387/ijdb.092936rh · Cited by 31 · see citing works
Early self-reproduction, the emergence of division mechanisms in protocells
Murtas, G. (2012) · Molecular BioSystems · doi:10.1039/c2mb25375e · Cited by 30 · see citing works
Todd, Z. R., Cohen, Z. R., Catling, D., Keller, S., & Black, R. (2022) · Langmuir · doi:10.1021/acs.langmuir.2c02118 · Cited by 24 · see citing works
Sunlight-initiated Chemistry of Aqueous Pyruvic Acid: Building Complexity in the Origin of Life
Griffith, E. C., Shoemaker, R. L., & Vaida, V. (2013) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-013-9349-y · Cited by 30 · see citing works
Dworkin, J. P., Gillette, J. S., Bernstein, M. P., Sandford, S. A., Allamandola, L. J., Elsila, J. E., Mcglothlin, D. R., & Zare, R. N. (2003) · Advances in Space Research · doi:10.1016/j.asr.2003.08.004 · Cited by 29 · see citing works
- Authors
- Deamer, D. W., & Pashley, R. M.
- Affiliations
- University of California, Davis (US)
- Australian National University (AU)
- Venue
- Origins of life and evolution of the biosphere
- Published
- 1989-01
- Volume
- 19
- Issue
- 1
- Pages
- 21-38
- ISSN
- 0169-6149 (ISSN-L)
- 1573-0875
- OpenAlex
- W2018664170
- Cited by
- 272
- References
- 27
- Citations by year
- 2026: 9 · 2025: 9 · 2024: 10 · 2023: 18 · 2022: 13 · 2021: 14 · 2020: 9 · 2019: 7 · 2018: 9 · 2017: 3 · 2016: 5 · 2015: 11 · 2014: 6 · 2013: 10 · 2012: 7
- FWCI
- 4.10
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Origins of Life and Evolution of Biospheres (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Aeronautics and Space Administration
- John Simon Guggenheim Memorial Foundation
- Australian National University
- National Institutes of Health
- National Center for Research Resources (RR01460-01)
- Topics
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Astro and Planetary Science
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Space Science and Extraterrestrial Life
- Keywords
- Murchison meteorite, CM2 chondrites, amphiphilic molecules, lipid-like compounds, membrane self-assembly, vesicle formation, polycyclic aromatic hydrocarbons, pyrene, fluoranthene, surfactants, monolayers, acidic surface groups, meteorite organic matter, origin of life
- MeSH terms
- Australia, Carbon, Chromatography, Thin Layer, Gas Chromatography-Mass Spectrometry, Membranes, Spectrum Analysis, Surface Properties
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