Brief report: Circadian melatonin, thyroid-stimulating hormone, prolactin, and cortisol levels in serum of young adults with autism
Abstract
An abnormal circadian pattern of melatonin was found in a group of young adults with an extreme autism syndrome. Although not out of phase, the serum melatonin levels differed from normal in amplitude and mesor. Marginal changes in diurnal rhythms of serum TSH and possibly prolactin were also recorded. Subjects with seizures tended to have an abnormal pattern of melatonin correlated with EEG changes. In others, a parallel was evidenced between thyroid function and impairment in verbal communication. There appears to be a tendency for various types of neuroendocrinological abnormalities in autistics, and melatonin, as well as possibly TSH and perhaps prolactin, could serve as biochemical variables of the biological parameters of the disease.
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The most consistent related finding in prepubertal children, pubertal adolescents and young adults with ASD is reduced melatonin levels in the evening.
“The most consistent related finding in prepubertal children, pubertal adolescents and young adults with ASD is reduced melatonin levels in the evening99–102.”
From Rhythms of life: circadian disruption and brain disorders across the lifespan (2019) · cites this paper as [100]
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,841 · see citing works
Diagnostic and Statistical Manual of Mental Disorders
&NA; (1988) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-198802020-00022 · Cited by 12,603 · see citing works
Diagnostic and Statistical Manual of Mental Disorders, 3rd ed
Kendell, R. E. (1980) · American Journal of Psychiatry · doi:10.1176/ajp.137.12.1630 · Cited by 5,201 · see citing works
American Journal of Mental Retardation
Staff (2008) · Encyclopedia of Special Education · doi:10.1002/9780470373699.speced0106 · Cited by 2,972 · see citing works
Wing, L., & Gould, J. (1979) · Journal of Autism and Developmental Disorders · doi:10.1007/bf01531288 · Cited by 2,587 · see citing works
Social and pragmatic deficits in autism: Cognitive or affective?
Baron‐Cohen, S. (1988) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02212194 · Cited by 737 · see citing works
Melatonin is a potent modulator of dopamine release in the retina
Dubocovich, M. L. (1983) · Nature · doi:10.1038/306782a0 · Cited by 512 · see citing works
Journal of Neural Transmission
(2013) · Journal of Neural Transmission · doi:10.1007/702.1435-1463 · Cited by 354 · see citing works
Brain Serotonin Concentration: Elevation Following Intraperitoneal Administration of Melatonin
Antón‐Tay, F., Chou, C., Anton, S. M., & Wurtman, R. J. (1968) · Science · doi:10.1126/science.162.3850.277 · Cited by 250 · see citing works
Psychopharmacology in Child and Adolescent Psychiatry: A Review of the Past Five Years
Campbell, M., & SPENCER, E. K. (1988) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-198805000-00001 · Cited by 182 · see citing works
Melatonin Receptors in Discrete Brain Areas of the Male Rat
Laudon, M., Nir, I., & Zisapel, N. (2008) · Neuroendocrinology · doi:10.1159/000125066 · Cited by 111 · see citing works
Self-citationUrinary cortisol circadian rhythm in a group of high-functioning children with autism
Richdale, A. L., & Prior, M. R. (1992) · Journal of Autism and Developmental Disorders · doi:10.1007/bf01048245 · Cited by 105 · see citing works
Chamberlain, R., & Herman, B. H. (1990) · Biological Psychiatry · doi:10.1016/0006-3223(90)90513-2 · Cited by 102 · see citing works
Inhibition by melatonin of dopamine release from rat hypothalamus: regulation of calcium entry
Zisapel, N., & Laudon, M. (1983) · Brain Research · doi:10.1016/0006-8993(83)90588-7 · Cited by 99 · see citing works
Catecholamines metabolism in infantile autism: A controlled study of 22 autistic children
Launay, J., Bursztejn, C., Ferrari, P., DREUX, C., Braconnier, A., Zarifian, E., Lancrenon, S., & Fermanian, J. (1987) · Journal of Autism and Developmental Disorders · doi:10.1007/bf01487064 · Cited by 94 · see citing works
Vitte, P. A., Harthé, C., Lestage, P. J., Claustrat, B., & Bobillier, P. (1988) · Journal of Pineal Research · doi:10.1111/j.1600-079x.1988.tb00787.x · Cited by 80 · see citing works
Waldhauser, F., Lieberman, H. R., Lynch, H. J., Waldhauser, M., Herkner, K. R., Frisch, H., Vierhapper, H., Waldhäusl, W. K., SCHEMPER, M., Wurtman, R. J., et al. (2008) · Neuroendocrinology · doi:10.1159/000124808 · Cited by 78 · see citing works
Roca, R. P., Blackman, M. R., Ackerley, M. B., Harman, S. M., & Gregerman, R. I. (1990) · Endocrine Research · doi:10.1080/07435809009107116 · Cited by 76 · see citing works
Humoral-endorphin blood levels in autistic, schizophrenic and healthy subjects
Weizman, R., Weizman, A., Tyano, S., Szekely, G., Weissman, B. A., & Sarne, Y. (1984) · Psychopharmacology · doi:10.1007/bf00427687 · Cited by 76 · see citing works
Melatonin assays in body fluids.
Arendt, J. (1978) · PubMed · Cited by 75 · see citing works
Electroretinograms in autism: a pilot study of b-wave amplitudes
RITVO, E. R., Creel, D. J., Realmuto, G., Crandall, A. S., Freeman, B. J., Bateman, J., Barr, R., Pingree, C., Coleman, M., & Purple, R. L. (1988) · American Journal of Psychiatry · doi:10.1176/ajp.145.2.229 · Cited by 74 · see citing works
Melatonin, pituitary function and stress in humans
Vaughan, G. M., McDonald, S. D., Jordan, R. M., Allen, J. P., BELL, R. D., & Stevens, E. A. (1979) · Psychoneuroendocrinology · doi:10.1016/0306-4530(79)90018-0 · Cited by 71 · see citing works
Plasma B-endorphin levels in patients with self-injurious behavior and stereotypy.
Sandman, C. A., Barron, J. L., Chicz-DeMet, A., & DeMet, E. M. (1990) · PubMed · Cited by 70 · see citing works
Elevated daytime melatonin concentrations in autism: A pilot study
RITVO, E. R., Ritvo, R., Yuwiler, A., MASON-BROTHERS, A., Freeman, B. J., & Plotkin, S. (1993) · European Child & Adolescent Psychiatry · doi:10.1007/bf02098862 · Cited by 69 · see citing works
Annals of Clinical Biochemistry
(1996) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1177/000456329603300125 · Cited by 69 · see citing works
Brief report: Plasma Β-endorphin and cortisol levels in autistic patients
Sandman, C. A., Barron, J. L., Chicz-DeMet, A., & DeMet, E. M. (1991) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02207000 · Cited by 53 · see citing works
Evidence for the presence of melatonin in the human brain
Kopp, N., Claustrat, B., & Tappaz, M. (1980) · Neuroscience Letters · doi:10.1016/0304-3940(80)90267-0 · Cited by 53 · see citing works
Yuwiler, A., RITVO, E. R., Bald, D., Kipper, D. A., & Koper, A. (1971) · Journal of Autism and Developmental Disorders · doi:10.1007/bf01540533 · Cited by 47 · see citing works
Alexiuk, N. A. M., & Vriend, J. P. (2008) · Neuroendocrinology · doi:10.1159/000125851 · Cited by 46 · see citing works
Blood serotonin concentrations and fenfluramine therapy in autistic children
Ho, H. H., Lockitch, G., Eaves, L., & Jacobson, B. E. (1986) · The Journal of Pediatrics · doi:10.1016/s0022-3476(86)80903-9 · Cited by 45 · see citing works
Serum melatonin levels in schizophrenic and schizoaffective hospitalized patients
Robinson, S., Rosca, P., Durst, R., Shai, U., Ghinea, C., Schmidt, U., & Nir, I. (1991) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1991.tb03133.x · Cited by 44 · see citing works
Self-citationBadcock, N. R., Spence, J. G., & Stern, L. M. (1987) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1177/000456328702400613 · Cited by 41 · see citing works
Herbert, J. (1985) · Europe PMC (PubMed Central) · Cited by 37 · see citing works
Dexamethasone Suppression Test in Autistic Children
Hoshino, Y., Ohno, Y., Murata, S., Yokoyama, F., Kaneko, M., & Kumashiro, H. (1984) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.1984.tb00793.x · Cited by 27 · see citing works
Implications of Social Deficits in Autism for Neurological Dysfunction
FEIN, D. A., Pennington, B. F., & Waterhouse, L. H. (1987) · Springer eBooks · doi:10.1007/978-1-4899-1992-2_7 · Cited by 23 · see citing works
Vaughan, G. M., Allen, J. P., & de la Peña, A. (1979) · PubMed · Cited by 11 · see citing works
Oxenkrug, G. F., REQUINTINA, P. J., McIntyre, I. M., & Davis, R. (1991) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780192620118.003.0009 · Cited by 4 · see citing works
Flagged first, then by citations
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Sorted by citations
Rhythms of life: circadian disruption and brain disorders across the lifespan
Logan, R. W., & McClung, C. A. (2019) · Nature Reviews Neuroscience · doi:10.1038/s41583-018-0088-y · Cited by 713 · see citing works
Abnormal melatonin synthesis in autism spectrum disorders
Melke, J., Goubran Botros, H., Chaste, P., Betancur, C., Nygren, G., Anckarsäter, H., Rastam, M., Ståhlberg, O., Gillberg, I. C., Delorme, R., et al. (2008) · Molecular Psychiatry · doi:10.1038/sj.mp.4002016 · Cited by 511 · see citing works
Pathophysiological distortions in time perception and timed performance
Allman, M. J., & Meck, W. H. (2011) · Brain · doi:10.1093/brain/awr210 · Cited by 461 · see citing works
Neurochemistry in the pathophysiology of autism.
McDougle, C. J., Erickson, C. A., Stigler, K. A., & Posey, D. J. (2005) · PubMed · Cited by 408 · see citing works
Sleep in children with autistic spectrum disorder
Cortesi, F., Giannotti, F., Ivanenko, A., & Johnson, K. (2010) · Sleep Medicine · doi:10.1016/j.sleep.2010.01.010 · Cited by 355 · see citing works
Sleep problems in autism: prevalence, cause, and intervention
Richdale, A. L. (1999) · Developmental Medicine & Child Neurology · doi:10.1017/s0012162299000122 · Cited by 345 · see citing works
Sleep in Children with Autism Spectrum Disorder
Souders, M. C., Jackson, S. Z., Eriksen, W., Sinko, R., Connell, J. E., Kerns, C. M., Schaaf, R. C., & Pinto‐Martin, J. A. (2017) · Current Psychiatry Reports · doi:10.1007/s11920-017-0782-x · Cited by 307 · see citing works
Nocturnal excretion of 6-sulphatoxymelatonin in children and adolescents with autistic disorder
Tordjman, S., Anderson, G. M., Pichard, N., Charbuy, H., & Touitou, Y. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.11.003 · Cited by 296 · see citing works
An investigation into sleep characteristics of children with autism and Asperger’s Disorder
PATZOLD, L., Richdale, A. L., & Tonge, B. J. (1998) · Journal of Paediatrics and Child Health · doi:10.1046/j.1440-1754.1998.00291.x · Cited by 288 · see citing works
Sleep and Autism Spectrum Disorders
Reynolds, A., & Malow, B. A. (2011) · Pediatric Clinics of North America · doi:10.1016/j.pcl.2011.03.009 · Cited by 260 · see citing works
Cortisol circadian rhythms and response to stress in children with autism
Corbett, B. A., Mendoza, S., Abdullah, M., Wegelin, J. A., & Levine, S. (2006) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2005.05.011 · Cited by 258 · see citing works
Gevi, F., Zolla, L., Gabriele, S., & Persico, A. M. (2016) · Molecular Autism · doi:10.1186/s13229-016-0109-5 · Cited by 251 · see citing works
Psychiatric problems in individuals with autism, their parents and siblings
Lainhart, J. E. (1999) · International Review of Psychiatry · doi:10.1080/09540269974177 · Cited by 242 · see citing works
Enhanced Cortisol Response to Stress in Children in Autism
Spratt, E. G., Nicholas, J. S., Brady, K. T., Carpenter, L. A., Hatcher, C. R., Meekins, K. A., Furlanetto, R. W., & Charles, J. M. (2012) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-011-1214-0 · Cited by 222 · see citing works
Carmassi, C., Palagini, L., Caruso, D., Masci, I., Nobili, L., Vita, A., & Dell’Osso, L. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00366 · Cited by 220 · see citing works
Etiology of infantile autism: a review of recent advances in genetic and neurobiological research.
Trottier, G., Srivastava, L. K., & Walker, C. D. (1999) · PubMed Central · Cited by 202 · see citing works
Hu, V. W., Sarachana, T., Kim, K. S., Nguyen, A., Kulkarni, S., Lowe, M. S., Luu, T. V., Lai, Y., & Lee, N. H. (2009) · Autism Research · doi:10.1002/aur.73 · Cited by 196 · see citing works
Wright, B., Sims, D., Smart, S., Alwazeer, A., Alderson‐Day, B., Allgar, V. L., Whitton, C., Tomlinson, H., Bennett, S. D., Jardine, J., et al. (2010) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-010-1036-5 · Cited by 196 · see citing works
Giannotti, F., Cortesi, F., Cerquiglini, A., & Bernabei, P. (2006) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0116-z · Cited by 211 · see citing works
The possible interplay of synaptic and clock genes in autism spectrum disorders
Bourgeron, T. (2007) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2007.72.020 · Cited by 185 · see citing works
Clock Genes and Altered Sleep–Wake Rhythms: Their Role in the Development of Psychiatric Disorders
Charrier, A., Olliac, B., Roubertoux, P. L., & Tordjman, S. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18050938 · Cited by 182 · see citing works
Mazzone, L., Postorino, V., Siracusano, M., Riccioni, A., & Curatolo, P. (2018) · Journal of Clinical Medicine · doi:10.3390/jcm7050102 · Cited by 172 · see citing works
Genes Controlling Affiliative Behavior as Candidate Genes for Autism
Yrigollen, C. M., Han, S. S., Kochetkova, A., Babitz, T., Chang, J. T., Volkmar, F. R., Leckman, J. F., & Grigorenko, E. L. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.11.015 · Cited by 172 · see citing works
Nicholas, B., Rudrasingham, V., Nash, S., Kirov, G., Owen, M. J., & Wimpory, D. C. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4001953 · Cited by 170 · see citing works
Sleep patterns in children with and without autism spectrum disorders: Developmental comparisons
Hodge, D., Carollo, T. M., Lewin, M., Hoffman, C. D., & Sweeney, D. P. (2014) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2014.03.037 · Cited by 171 · see citing works
Circadian rhythms and sleep in children with autism
Glickman, G. L. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.11.017 · Cited by 171 · see citing works
Circadian regulation of pineal gland rhythmicity
Borjigin, J., Zhang, L. S., & Calinescu, A. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.07.009 · Cited by 172 · see citing works
Román, G. C. (2007) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2007.06.023 · Cited by 166 · see citing works
The serotonin-N-acetylserotonin-melatonin pathway as a biomarker for autism spectrum disorders
Pagan, C., Delorme, R., Callebert, J., Goubran-Botros, H., Amsellem, F., Drouot, X., Boudebesse, C., Le Dudal, K., Ngo-Nguyen, N., Laouamri, H., et al. (2014) · Translational Psychiatry · doi:10.1038/tp.2014.120 · Cited by 165 · see citing works
Autism as a Disorder of Biological and Behavioral Rhythms: Toward New Therapeutic Perspectives
Tordjman, S., Davlantis, K. S., Georgieff, N., Geoffray, M., Speranza, M., Anderson, G. M., Xavier, J., Botbol, M., Oriol, C., Bellissant, É., et al. (2015) · Frontiers in Pediatrics · doi:10.3389/fped.2015.00001 · Cited by 162 · see citing works
Novel and Emerging Treatments for Autism Spectrum Disorders: A Systematic Review
Rossignol, D. A. (2009) · Annals of Clinical Psychiatry · doi:10.1177/104012370902100404 · Cited by 162 · see citing works
A review of rhythm and responsiveness of cortisol in individuals with autism spectrum disorders
Taylor, J. L., & Corbett, B. A. (2014) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2014.07.015 · Cited by 156 · see citing works
Bishop, L., Minshew, N. J., Mazefsky, C. A., & Eack, S. M. (2016) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-016-2910-6 · Cited by 155 · see citing works
Adams, J. B., Holloway, C. E., George, F., & Quig, D. (2006) · Biological Trace Element Research · doi:10.1385/bter:110:3:193 · Cited by 154 · see citing works
Melatonin: A review of its potential functions and effects on neurological diseases
Günata, M., Parlakpınar, H., & Acet, A. (2019) · Revue Neurologique · doi:10.1016/j.neurol.2019.07.025 · Cited by 154 · see citing works
Sleep problems of children with pervasive developmental disorders: correlation with parental stress
Doo, S., & Wing, Y. K. (2006) · Developmental Medicine & Child Neurology · doi:10.1017/s001216220600137x · Cited by 145 · see citing works
Hypothalamic‐Pituitary‐Adrenocortical Axis: Neuropsychiatric Aspects
Jacobson, L. (2014) · Comprehensive physiology · doi:10.1002/cphy.c130036 · Cited by 152 · see citing works
Sleep Problems in 2- to 5-Year-Olds With Autism Spectrum Disorder and Other Developmental Delays
Reynolds, A., Soke, G. N., Sabourin, K. R., Hepburn, S., Katz, T., Wiggins, L. D., Schieve, L. A., & Levy, S. E. (2019) · PEDIATRICS · doi:10.1542/peds.2018-0492 · Cited by 137 · see citing works
Tordjman, S., Najjar, I., Bellissant, E., Anderson, G., Barburoth, M., Cohen, D., Jaafari, N., Schischmanoff, O., Fagard, R., Lagdas, E., et al. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms141020508 · Cited by 132 · see citing works
Goldman, S. E., Adkins, K. W., Calcutt, M. W., Carter, M. D., Goodpaster, R. L., Wang, L., Shi, Y., Burgess, H. J., Hachey, D. L., & Malow, B. A. (2014) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-014-2123-9 · Cited by 133 · see citing works
van Gent, T., Heijnen, C. J., & Treffers, P. D. A. (1997) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1997.tb01518.x · Cited by 128 · see citing works
Tordjman, S., Anderson, G. M., Bellissant, E., Botbol, M., Charbuy, H., Camus, F., Graignic, R., Kermarrec, S., Fougerou, C., Cohen, D., et al. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.04.013 · Cited by 129 · see citing works
Sleep disorders, epilepsy, and autism
Malow, B. A. (2004) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/mrdd.20023 · Cited by 128 · see citing works
Devlin, S., Healy, O., Leader, G., & Hughes, B. M. (2010) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-010-1149-x · Cited by 127 · see citing works
Sleep in autism Spectrum disorder and attention deficit hyperactivity disorder
Singh, K., & Zimmerman, A. W. (2015) · Seminars in Pediatric Neurology · doi:10.1016/j.spen.2015.03.006 · Cited by 126 · see citing works
Social timing, clock genes and autism: a new hypothesis
Wimpory, D., Nicholas, B., & Nash, S. (2002) · Journal of Intellectual Disability Research · doi:10.1046/j.1365-2788.2002.00423.x · Cited by 116 · see citing works
Media Use and Sleep Among Boys With Autism Spectrum Disorder, ADHD, or Typical Development
Engelhardt, C. R., Mazurek, M. O., & Sohl, K. (2013) · PEDIATRICS · doi:10.1542/peds.2013-2066 · Cited by 116 · see citing works
Characterizing Sleep in Adolescents and Adults with Autism Spectrum Disorders
Goldman, S. E., Alder, M. L., Burgess, H. J., Corbett, B. A., Hundley, R. J., Wofford, D. D., Fawkes, D. B., Wang, L., Laudenslager, M. L., & Malow, B. A. (2017) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-017-3089-1 · Cited by 116 · see citing works
Sleep in Autism Spectrum Disorders
Veatch, O. J., Maxwell-Horn, A. C., & Malow, B. A. (2015) · Current Sleep Medicine Reports · doi:10.1007/s40675-015-0012-1 · Cited by 114 · see citing works
Mutation screening of melatonin-related genes in patients with autism spectrum disorders
Jönsson, L., Ljunggren, E., Bremer, A., Pedersen, C. T., Landén, M., Thuresson, K., Giacobini, M., & Melke, J. (2010) · BMC Medical Genomics · doi:10.1186/1755-8794-3-10 · Cited by 113 · see citing works
Pagan, C., Goubran‐Botros, H., Delorme, R., Benabou, M., Lemière, N., Murray, K., Amsellem, F., Callebert, J., Chaste, P., Jamain, S., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-02152-x · Cited by 113 · see citing works
Sleep problems of children with pervasive developmental disorders: correlation with parental stress
MRCPCH, S. D., & Wing, Y. K. (2007) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.2006.tb01334.x · Cited by 107 · see citing works
Sleep Disturbances in Children With Psychiatric Disorders
Ivanenko, A., & Johnson, K. (2008) · Seminars in Pediatric Neurology · doi:10.1016/j.spen.2008.03.008 · Cited by 104 · see citing works
The Pineal Gland from Development to Function
Sapède, D., & Cau, E. (2013) · Current Topics in Developmental Biology · doi:10.1016/b978-0-12-416021-7.00005-5 · Cited by 102 · see citing works
Tsai, L. Y. (1999) · Psychosomatic Medicine · doi:10.1097/00006842-199909000-00008 · Cited by 99 · see citing works
Sleep problems in children with autism spectrum disorder: a multicenter survey
Chen, H., Yang, T., Chen, J., Chen, L., Dai, Y., Zhang, J., Li, L., Jia, F., Wu, L.-J., Hao, Y., et al. (2021) · BMC Psychiatry · doi:10.1186/s12888-021-03405-w · Cited by 100 · see citing works
Guenolé, F., Godbout, R., Nicolas, A., Franco, P., Claustrat, B., & Baleyte, J. (2011) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2011.02.001 · Cited by 96 · see citing works
Sleep Patterns in Autism Spectrum Disorders
Johnson, K., Giannotti, F., & Cortesi, F. (2009) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2009.04.001 · Cited by 93 · see citing works
Lower Cortisol and Higher ACTH Levels in Individuals with Autism
Ćurin, J. M., Terzić, J., Petković, Z. B., Zekan, L., Marinovic‐Terzić, I., & Šušnjara, I. M. (2003) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1025019030121 · Cited by 92 · see citing works
Lopata, C. J., Volker, M. A., Putnam, S. K., Thomeer, M. L., & Nida, R. E. (2008) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-008-0575-5 · Cited by 92 · see citing works
Tordjman, S., Anderson, G. M., Kermarrec, S., Bonnot, O., Geoffray, M., Brailly‐Tabard, S., Chaouch, A., Colliot, I., Trabado, S., Bronsard, G., et al. (2014) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2014.08.010 · Cited by 87 · see citing works
Autism Spectrum Disorder and Sleep
Johnson, K., & Zarrinnegar, P. (2020) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2020.08.012 · Cited by 87 · see citing works
Are circadian rhythms new pathways to understand Autism Spectrum Disorder?
Geoffray, M., Nicolas, A., Speranza, M., & Georgieff, N. (2016) · Journal of Physiology-Paris · doi:10.1016/j.jphysparis.2017.06.002 · Cited by 83 · see citing works
Dissanayake, C., Bui, M., Huggins, R., & Loesch, D. Z. (2006) · Development and Psychopathology · doi:10.1017/s0954579406060202 · Cited by 81 · see citing works
Low maternal melatonin level increases autism spectrum disorder risk in children
Braam, W., Ehrhart, F., Evelo, C. T., Maas, A. P. H. M., Smits, M. G., & Curfs, L. (2018) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2018.02.017 · Cited by 80 · see citing works
Relation of Melatonin to Sleep Architecture in Children with Autism
Leu, R. M., Beyderman, L., Botzolakis, E. J., Surdyka, K., Wang, L., & Malow, B. A. (2010) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-010-1072-1 · Cited by 77 · see citing works
Mulder, E. J., Anderson, G. M., Kemperman, R. F. J., Oosterloo-Duinkerken, A., Minderaa, R. B., & Kema, I. P. (2009) · Neuropsychobiology · doi:10.1159/000258640 · Cited by 76 · see citing works
Melatonin for sleep disorders in people with autism: Systematic review and meta-analysis
Nogueira, H. A., de Castro, C. T., da Silva, D. C. G., & Pereira, M. E. (2022) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2022.110695 · Cited by 73 · see citing works
Autism spectrum disorder (ASD): Disturbance of the melatonin system and its implications
Wu, Z., Huang, S., Zou, J.-J., Wang, Q.-X., Naveed, M., Bao, H.-N., Wang, W., Fukunaga, K., & Han, F. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110496 · Cited by 72 · see citing works
Slower cortisol response during ACTH stimulation test in autistic children
Ćurin, J. M., Marinovic‐Terzić, I., Bujas-Petković, Z., Zekan, L., Škrabić, V., Đogaš, Z., & Terzić, J. (2007) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-007-0632-1 · Cited by 70 · see citing works
The status of pharmacotherapy for autism spectrum disorders
Myers, S. M. (2007) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.8.11.1579 · Cited by 69 · see citing works
Baker, E. K., & Richdale, A. L. (2017) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-017-3042-3 · Cited by 68 · see citing works
Sleep in children with autism spectrum disorders
Johnson, K., & Malow, B. A. (2008) · Current Treatment Options in Neurology · doi:10.1007/s11940-008-0038-5 · Cited by 66 · see citing works
Malow, B. A., & McGrew, S. G. (2008) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2008.04.004 · Cited by 65 · see citing works
Comparing stress and arousal systems in response to different social contexts in children with ASD
Corbett, B. A., Muscatello, R. A., & Baldinger, C. (2018) · Biological Psychology · doi:10.1016/j.biopsycho.2018.12.010 · Cited by 62 · see citing works
Lorsung, E., Ramanujam, K., & Cao, R. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.642745 · Cited by 63 · see citing works
Parent-Of-Origin Effects in Autism Identified through Genome-Wide Linkage Analysis of 16,000 SNPs
Fradin, D., Cheslack‐Postava, K., Ladd‐Acosta, C., Newschaffer, C. J., Chakravarti, A., Arking, D. E., Feinberg, A. P., & Fallin, M. D. (2010) · PLoS ONE · doi:10.1371/journal.pone.0012513 · Cited by 62 · see citing works
Wetterberg, L., Bratlid, T., von Knorring, L., Eberhard, G., & Yuwiler, A. (1999) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s004060050095 · Cited by 58 · see citing works
A comparative study of circadian rhythm functioning and sleep in people with Asperger syndrome
Hare, D. J., Jones, S. H., & Evershed, K. (2006) · Autism · doi:10.1177/1362361306068509 · Cited by 58 · see citing works
Deliens, G., & Peigneux, P. (2019) · Developmental Medicine & Child Neurology · doi:10.1111/dmcn.14235 · Cited by 63 · see citing works
Theoretical aspects of autism: biomarkers—a review
Ratajczak, H. V. (2011) · Journal of Immunotoxicology · doi:10.3109/1547691x.2010.538749 · Cited by 58 · see citing works
CATCH (Cortisol Apta WATCH): ‘Bio-mimic alarm’ to track Anxiety, Stress, Immunity in human sweat
Pali, M. L., Jagannath, B., Lin, K., Upasham, S., Sankhalab, D., Upashama, S., Muthukumar, S., & Prasad, S. (2021) · Electrochimica Acta · doi:10.1016/j.electacta.2021.138834 · Cited by 56 · see citing works
Possible Metabolic Alterations among Autistic Male Children: Clinical and Biochemical Approaches
Hassan, M. H., Desoky, T., Sakhr, H. M., Gabra, R. H., & Bakri, A. H. (2018) · Journal of Molecular Neuroscience · doi:10.1007/s12031-018-1225-9 · Cited by 56 · see citing works
Neuroendocrine Aspects of Tourette Syndrome
Martino, D., Macerollo, A., & Leckman, J. F. (2013) · International review of neurobiology · doi:10.1016/b978-0-12-411546-0.00009-3 · Cited by 55 · see citing works
Rzepka-Migut, B., & Paprocka, J. (2020) · Brain Sciences · doi:10.3390/brainsci10040219 · Cited by 55 · see citing works
Melatonin in children with autistic spectrum disorders: recent and practical data
Doyen, C., Mighiu, D., Kaye, K., Colineaux, C., Beaumanoir, C., Mouraeff, Y., Rieu, C., Paubel, P., & Contejean, Y. (2011) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-011-0162-8 · Cited by 54 · see citing works
Melatonin in treatment of chronic sleep disorders in adults with autism: a retrospective study
Galli-Carminati, G. (2009) · Swiss Medical Weekly · doi:10.4414/smw.2009.12342 · Cited by 52 · see citing works
Frye, R. E., Wynne, R. A., Rose, S., Slattery, J. M., Delhey, L. M., Tippett, M., Kahler, S. G., Bennuri, S. C., Melnyk, S., Sequeira, J. M., et al. (2017) · Journal of Neuroendocrinology · doi:10.1111/jne.12461 · Cited by 52 · see citing works
The Relationship between Autism Spectrum Disorder and Melatonin during Fetal Development
Jin, Y., Choi, J., Won, J., & Hong, Y. (2018) · Molecules · doi:10.3390/molecules23010198 · Cited by 52 · see citing works
Melatonin and Comorbidities in Children with Autism Spectrum Disorder
Gagnon, K., & Godbout, R. (2018) · Current Developmental Disorders Reports · doi:10.1007/s40474-018-0147-0 · Cited by 52 · see citing works
Patel, N. S., Crider, A., Pandya, C. D., Ahmed, A. O., & Pillai, A. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9178-2 · Cited by 49 · see citing works
Adolescence, stress and cortisol in autism spectrum disorders
Corbett, B., & Simon, D. (2013) · OA Autism · doi:10.13172/2052-7810-1-1-348 · Cited by 50 · see citing works
Corticosteroid and neurosteroid dysregulation in an animal model of autism, BTBR mice
Frye, C. A., & Llaneza, D. C. (2010) · Physiology & Behavior · doi:10.1016/j.physbeh.2010.03.005 · Cited by 52 · see citing works
Sleep Disturbances in Children Affected by Autism Spectrum Disorder
Galli, J., Loi, E., Visconti, L. M., Mattei, P., Eusebi, A., Calza, S., Fazzi, E. M., & ASD Collaborative Group (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.736696 · Cited by 50 · see citing works
Abnormal Sleep Patterns Associated with Autism
Stores, G., & Wivggs, L. (1998) · Autism · doi:10.1177/1362361398022004 · Cited by 50 · see citing works
Tomarken, A. J., Han, G. T., & Corbett, B. A. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.08.016 · Cited by 49 · see citing works
Ramelteon for Insomnia in Two Youths with Autistic Disorder
Stigler, K. A., Posey, D. J., & McDougle, C. J. (2006) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2006.16.631 · Cited by 49 · see citing works
Dell’Osso, L., Massoni, L., Battaglini, S., Cremone, I. M., Carmassi, C., & Carpita, B. (2022) · Annals of General Psychiatry · doi:10.1186/s12991-022-00390-6 · Cited by 48 · see citing works
Assessment and Pharmacologic Treatment of Sleep Disturbance in Autism
Johnson, K., & Malow, B. A. (2008) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2008.06.006 · Cited by 48 · see citing works
Carter, M. D., Calcutt, M. W., Malow, B. A., Rose, K. L., & Hachey, D. L. (2012) · Journal of Mass Spectrometry · doi:10.1002/jms.2051 · Cited by 48 · see citing works
- Authors
- Nir, I., Meir, D., Zilber, N., Knobler, H., Hadjez, J., & Lerner, Y.
- Affiliations
- Hebrew University of Jerusalem (IL)
- Venue
- Journal of Autism and Developmental Disorders
- Published
- 1995-12
- Volume
- 25
- Issue
- 6
- Pages
- 641-654
- ISSN
- 0162-3257 (ISSN-L)
- 1573-3432
- OpenAlex
- W1988854674
- Cited by
- 221
- References
- 37
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 9 · 2023: 6 · 2022: 11 · 2021: 12 · 2020: 11 · 2019: 10 · 2018: 12 · 2017: 13 · 2016: 8 · 2015: 11 · 2014: 12 · 2013: 16 · 2012: 6
- FWCI
- 0.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Autism and Developmental Disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- autism spectrum disorder, melatonin, circadian rhythm, thyroid-stimulating hormone, prolactin, cortisol, diurnal cycle, seizures, EEG, verbal communication impairment, neuroendocrine abnormalities, serum biomarkers, young adults
- MeSH terms
- Adolescent, Adult, Autistic Disorder, Circadian Rhythm, Humans, Hydrocortisone, Male, Melatonin, Prolactin, Radioimmunoassay, Thyrotropin
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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