Very long chain fatty acids in higher animals: a review

The Metabolic Basis of Inherited Disease.

(1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-108-3-503_7 · Cited by 7,807 · see citing works

Studies and Perspectives of Protein Kinase C

Nishizuka, Y. (1986) · Science · doi:10.1126/science.3014651 · Cited by 5,089 · see citing works

ABC Transporters: From Microorganisms to Man

Higgins, C. F. (1992) · Annual Review of Cell Biology · doi:10.1146/annurev.cb.08.110192.000435 · Cited by 3,985 · see citing works

Leukotrienes and Lipoxins: Structures, Biosynthesis, and Biological Effects

Samuelsson, B. O., Dahlén, S., LINDGREN, J. Å., Rouzer, C. A., & Serhan, C. N. (1987) · Science · doi:10.1126/science.2820055 · Cited by 2,233 · see citing works

ARACHIDONIC ACID METABOLISM

Needleman, P., Truk, J., Jakschik, B. A., Morrison, A. R., & Lefkowith, J. B. (1986) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.55.070186.000441 · Cited by 1,809 · see citing works

Carnitine—metabolism and functions

Bremer, J. (1983) · Physiological Reviews · doi:10.1152/physrev.1983.63.4.1420 · Cited by 1,666 · see citing works

Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters

Mosser, J., Douar, A.-M., Sarde, C.-O., Kioschis, P., Feil, R., Moser, H., Poustka, A.-M., Mandel, J.-L., & Aubourg, P. (1993) · Nature · doi:10.1038/361726a0 · Cited by 1,202 · see citing works

Biochemical and functional effects of prenatal and postnatal omega 3 fatty acid deficiency on retina and brain in rhesus monkeys.

Neuringer, M. D., CONNOR, W. E., Lin, D. S., Barstad, L., & Luck, S. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.11.4021 · Cited by 914 · see citing works

The regulation and cellular functions of phosphatidylcholine hydrolysis

Billah, M. M., & Anthes, J. C. (1990) · Biochemical Journal · doi:10.1042/bj2690281 · Cited by 852 · see citing works

Peroxisomal and Mitochondrial Defects in the Cerebro-Hepato-Renal Syndrome

Goldfischer, S. L., Moore, C. L., Johnson, T., Spiro, A. J., Valsamis, M. P., Wisniewski, H. K., Ritch, R. H., Norton, W. T., Rapin, I., & Gartner, L. M. (1973) · Science · doi:10.1126/science.182.4107.62 · Cited by 791 · see citing works

The Metabolism of Phosphoinositide-Derived Messenger Molecules

Majerus, P. W., Connolly, T. M., Deckmyn, H., Ross, T. S., Bross, T. E., Ishii, H., Bansal, V. S., & Wilson, D. B. (1986) · Science · doi:10.1126/science.3024320 · Cited by 708 · see citing works

The permeability barrier in mammalian epidermis.

Elias, P. M., & Friend, D. S. (1975) · The Journal of Cell Biology · doi:10.1083/jcb.65.1.180 · Cited by 697 · see citing works

Ceramide activates heterotrimeric protein phosphatase 2A

Dobrowsky, R. T., Kamibayashi, C., Mumby, M. C., & Hannun, Y. A. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)82288-8 · Cited by 666 · see citing works

The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a 4-desaturase.

Voss, A., Reinhart, M., Sankarappa, S. K., & Sprecher, H. W. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54882-1 · Cited by 665 · see citing works

Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation.

Kim, M. Y., Linardic, C. M., Obeid, L. M., & Hannun, Y. A. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)52461-3 · Cited by 628 · see citing works

CARNITINE

BIEBER, L. L. (1988) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.57.070188.001401 · Cited by 626 · see citing works

A Potential Second Messenger Role for Unsaturated Fatty Acids: Activation of Ca 2+ -Dependent Protein Kinase

McPhail, L. C., Clayton, C. C., & Snyderman, R. (1984) · Science · doi:10.1126/science.6231726 · Cited by 616 · see citing works

Fatty acid and fatty aldehyde composition of the major brain lipids in normal human gray matter, white matter, and myelin

O'Brien, J. S., & Sampson, E. L. (1965) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39620-6 · Cited by 482 · see citing works

Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation.

Okazaki, T., Bielawska, A. E., Bell, R. M., & Hannun, Y. A. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)55472-7 · Cited by 471 · see citing works

Qualitative alteration in substrate specificity of mitochondrial monoamine oxidase in brain

Moskvitina, T. A., Kamyshanskaya, N. S., Kaverina, L. P., & Gorkin, V. Z. (1976) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1976.tb04462.x · Cited by 440 · see citing works

Activation of the Sphingomyelin Signaling Pathway in Intact EL4 Cells and in a Cell-Free System By IL-1β

Mathias, S., Younes, A., Kan, C.-C., Orlow, I., Joseph, C. K., & Kolesnick, R. (1993) · Science · doi:10.1126/science.8424175 · Cited by 433 · see citing works

Phosphatidylcholine Hydrolysis by Phospholipase D Determines Phosphatidate and Diglyceride Levels in Chemotactic Peptide-stimulated Human Neutrophils

Billah, M. M., Eckel, S., Mullmann, T. J., Egan, R. W., & Siegel, M. I. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)71460-9 · Cited by 424 · see citing works

Untitled work

Moser, H. (1981) · doi:10.1212/wnl.31.10.1241 · Cited by 396 · see citing works

Structural and functional features of different types of cytoplasmic fatty acid-binding proteins

Veerkamp, J. H., Peeters, R. A., & Maatman, R. G. H. J. (1991) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(91)90244-c · Cited by 387 · see citing works

Ceramide stimulates a cytosolic protein phosphatase.

Dobrowsky, R., & Hannun, Y. A. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42727-5 · Cited by 376 · see citing works

Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha.

Mathias, S., Dressler, K. A., & Kolesnick, R. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.22.10009 · Cited by 373 · see citing works

A Human Gene Responsible for Zellweger Syndrome That Affects Peroxisome Assembly

Shimozawa, N., Tsukamoto, T., Suzuki, Y., Orii, T., Shirayoshi, Y., Mori, T., & Fujiki, Y. (1992) · Science · doi:10.1126/science.1546315 · Cited by 361 · see citing works

Lignoceric acid is oxidized in the peroxisome: implications for the Zellweger cerebro-hepato-renal syndrome and adrenoleukodystrophy.

Singh, I., Moser, A. E., Goldfischer, S. L., & Moser, H. W. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.13.4203 · Cited by 348 · see citing works

Unsaturated fatty acids stimulate NADPH-dependent superoxide production by cell-free system derived from macrophages

Bromberg, Y., & Pick, E. (1984) · Cellular Immunology · doi:10.1016/0008-8749(84)90066-2 · Cited by 339 · see citing works

Signal transduction via phosphatidylcholine cycles

Pelech, S., & Vance, D. E. (1989) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(89)90086-8 · Cited by 311 · see citing works

Sphingolipid breakdown products: anti-proliferative and tumor-suppressor lipids

Hannun, Y. A., & Linardic, C. M. (1993) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(93)90001-5 · Cited by 281 · see citing works

The Cerebrohepatorenal (Zellweger) Syndrome

Moser, A. E., Singh, I., Brown, F. R., Solish, G. I., Kelley, R. I., Benke, P. J., & Moser, H. W. (1984) · New England Journal of Medicine · doi:10.1056/nejm198405033101802 · Cited by 271 · see citing works

The Inflammatory Myelinopathy of Adreno-Leukodystrophy: Cells, Effector Molecules, and Pathogenetic Implications

POWERS, J. M., LIU, Y., MOSER, A. B., & MOSER, H. W. (1992) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-199211000-00007 · Cited by 265 · see citing works

Lysophosphatidic acid, but not phosphatidic acid, is a potent Ca2(+)-mobilizing stimulus for fibroblasts. Evidence for an extracellular site of action.

Jalink, K., van Corven, E. J., & Moolenaar, W. H. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)38335-8 · Cited by 264 · see citing works

A new peroxisomal disorder with enlarged peroxisomes and a specific deficiency of acyl-CoA oxidase (pseudo-neonatal adrenoleukodystrophy).

Poll‐The, B. T., Roels, F., de Baulny, H. O., Scotto, J. M., Vamecq, J., Schutgens, R. B. H., Wanders, R. J. A., van Roermund, C. W. T., van Wijland, M. J. A., & Schram, A. W. (1988) · Europe PMC (PubMed Central) · Cited by 258 · see citing works

Cerebro-hepato-renal syndrome of Zellweger

Danks, D. M., Tippett, P., Adams, C., & Campbell, P. E. (1975) · The Journal of Pediatrics · doi:10.1016/s0022-3476(75)80967-x · Cited by 245 · see citing works

Neurological Mutations Affecting Myelination

Lantos, P. L. (1981) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.44.6.561 · Cited by 244 · see citing works

A Two-Year Trial of Oleic and Erucic Acids (“Lorenzo's Oil”) as Treatment for Adrenomyeloneuropathy

Aubourg, P., Adamsbaum, C., Lavallard-Rousseau, M.-C., Rocchiccioli, F., Cartier, N., Jambaque, I., Jakobezak, C., Lemaitre, A., Boureau, F., Wolf, C., et al. (1993) · New England Journal of Medicine · doi:10.1056/nejm199309093291101 · Cited by 242 · see citing works

Adrenoleukodystrophy: Phenotypic variability and implications for therapy

Moser, H. W., Moser, A. B., Smith, K. D., Bergin, A., Borel, J., Shankroff, J., Stine, O. C., Merette, C., Ott, J., Krivit, W., et al. (1992) · Journal of Inherited Metabolic Disease · doi:10.1007/bf01799621 · Cited by 239 · see citing works

Adrenoleukodystrophy: impaired oxidation of very long chain fatty acids in white blood cells, cultured skin fibroblasts, and amniocytes

Singh, I., Moser, A. E., Moser, H. W., & Kishimoto, Y. (1984) · Pediatric Research · doi:10.1203/00006450-198403000-00016 · Cited by 234 · see citing works

Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome

Gärtner, J., Moser, H. W., & Valle, D. L. (1992) · Nature Genetics · doi:10.1038/ng0492-16 · Cited by 228 · see citing works

Effects of free fatty acids on release of superoxide and on change of shape by human neutrophils. Reversibility by albumin.

Badwey, J. A., Curnutte, J. T., Robinson, J. M., Berde, C. B., Karnovsky, M. J., & Karnovsky, M. J. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)42874-2 · Cited by 227 · see citing works

Peroxisomal lignoceroyl-CoA ligase deficiency in childhood adrenoleukodystrophy and adrenomyeloneuropathy.

Lazo, O., Contreras, M., Hashmi, M., Stanley, W. S., Irazú, C. E., & Singh, I. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.20.7647 · Cited by 219 · see citing works

Regulation of the biosynthesis of two distinct fatty acid-binding proteins in rat liver and intestine. Influences of sex difference and of clofibrate.

Bass, N. M., Manning, J. A., Ockner, R. K., et al. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)89610-7 · Cited by 213 · see citing works

Peroxisomal bifunctional enzyme deficiency.

Watkins, P. A., Chen, W. W., Harris, C., Höefler, G., Hoefler, S., Blake, D., Balfe, A., Kelley, R. I., Moser, A. B., & Beard, M. E. (1989) · Journal of Clinical Investigation · doi:10.1172/jci113956 · Cited by 212 · see citing works

Adrenoleukodystrophy: Elevated C26 fatty acid in cultured skin fibroblasts

Moser, H. W., Moser, A. B., Kawamura, N., Murphy, J. V., Suzuki, K., Schaumburg, H. H., & Kishimoto, Y. (1980) · Annals of Neurology · doi:10.1002/ana.410070607 · Cited by 209 · see citing works

Functions of fatty acid binding proteins

Kaikaus, R. M., Bass, N. M., & Ockner, R. K. (1990) · Cellular and Molecular Life Sciences · doi:10.1007/bf01939701 · Cited by 208 · see citing works

Dietary erucic acid therapy for X‐linked adrenoleukodystrophy

Rizzo, W. B., Leshner, R. T., Odone, A., Dammann, A. L., Craft, D. A., Jensen, M. E., Jennings, S. S., Davis, S., Jaitly, R., & Sgro, J. A. (1989) · Neurology · doi:10.1212/wnl.39.11.1415 · Cited by 207 · see citing works

Complete nucleotide sequence of cDNA and predicted amino acid sequence of rat acyl-CoA oxidase.

Miyazawa, S., Hayashi, H., Hijikata, M., Ishii, N., Furuta, S., Kagamiyama, H., Osumi, T., & Hashimoto, T. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47539-4 · Cited by 205 · see citing works

Covalently Bound Lipids of Human Stratum Corneum

Wertz, P. W., Madison, K. C., & Downing, D. T. (1989) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep13071317 · Cited by 205 · see citing works

Tumour necrosis factor (cachectin) induces phospholipase A2 activity and synthesis of a phospholipase A2-activating protein in endothelial cells

Clark, M. A., Chen, M. J., Crooke, S. T., & Bomalaski, J. S. (1988) · Biochemical Journal · doi:10.1042/bj2500125 · Cited by 203 · see citing works

Human peroxisomal 3-oxoacyl-coenzyme A thiolase deficiency.

Schram, A. W., Goldfischer, S. L., van Roermund, C. W. T., Brouwer-Kelder, E. M., Collins, J. C., Hashimoto, T., Heymans, H. S. A., van den BOSCH, H., Schutgens, R. B. H., & Tager, J. M. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.8.2494 · Cited by 200 · see citing works

Sphingolipid activator protein deficiency in a 16-week-old atypical Gaucher disease patient and his fetal sibling: Biochemical signs of combined sphingolipidoses

HARZER, K., Paton, B. C., Poulos, A., Kustermann‐Kuhn, B., Roggendorf, W., Grisar, T., & Popp, M. (1989) · European Journal of Pediatrics · doi:10.1007/bf02024331 · Cited by 199 · see citing works

Ceramidase Deficiency in Farber's Disease (Lipogranulomatosis)

Sugita, M., Dulaney, J. T., & Moser, H. W. (1972) · Science · doi:10.1126/science.178.4065.1100 · Cited by 197 · see citing works

Covalently bound ω-hydroxyacylsphingosine in the stratum corneum

Wertz, P. W., & Downing, D. T. (1987) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(87)90290-6 · Cited by 189 · see citing works

Changes in the fatty acid composition of cerebrosides and sulfatides of human nervous tissue with age

Svennerholm, L., & Ställberg-Stenhagen, S. (1968) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)43122-0 · Cited by 188 · see citing works

Peroxisomal bifunctional protein from rat liver is a trifunctional enzyme possessing 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and delta 3, delta 2-enoyl-CoA isomerase activities.

Palosaari, P. M., & Hiltunen, J. K. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)39819-9 · Cited by 181 · see citing works

Acyl-CoA synthetase in rat liver peroxisomes. Computer-assisted analysis of cell fractionation experiments.

Krisans, S. K., Mortensen, R. M., & Lazarow, P. B. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)43434-5 · Cited by 178 · see citing works

Peroxisomal disorders in neurology

Wanders, R. J. A., Heymans, H. S. A., Schutgens, R. B. H., Barth, P. G., van den BOSCH, H., & Tager, J. M. (1988) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(88)90203-1 · Cited by 176 · see citing works

Effects of long-chain, saturated fatty acids on membrane microviscosity and adrenocorticotropin responsiveness of human adrenocortical cells in vitro.

Whitcomb, R. W., Linehan, W. M., & Knazek, R. A. (1988) · Journal of Clinical Investigation · doi:10.1172/jci113292 · Cited by 168 · see citing works

Phosphatidic acid as a second messenger in human polymorphonuclear leukocytes. Effects on activation of NADPH oxidase.

Agwu, D. E., McPhail, L. C., Sozzani, S., Bass, D., & McCall, C. E. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115336 · Cited by 165 · see citing works

Glucosylceramides of pig epidermis: structure determination.

Wertz, P. W., & Downing, D. T. (1983) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37896-2 · Cited by 165 · see citing works

Molecular cloning and nucleotide sequence of the cDNA for rat peroxisomal enoyl-CoA: hydratase-3-hydroxyacyl-CoA dehydrogenase bifunctional enzyme.

Osumi, T., Ishii, N., Hijikata, M., Kamijo, K., Ozasa, H., Furuta, S., Miyazawa, S., Kondo, K., Inoue, K., & Kagamiyama, H. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)39435-8 · Cited by 163 · see citing works

Lignoceroyl‐CoASH ligase: enzyme defect in fatty acid β‐oxidation system in X‐linked childhood adrenoleukodystrophy

Hashmi, M., Stanley, W. S., & Singh, I. (1986) · FEBS Letters · doi:10.1016/0014-5793(86)80256-3 · Cited by 162 · see citing works

The Lipid Secretion of the Meibomian Glands

Tiffany, J. M. (1987) · Advances in lipid research · doi:10.1016/b978-0-12-024922-0.50005-9 · Cited by 159 · see citing works

Structural analysis of cDNA for rat peroxisomal 3-ketoacyl-CoA thiolase.

Hijikata, M., Ishii, N., Kagamiyama, H., et al. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47542-4 · Cited by 158 · see citing works

Direct demonstration that the deficient oxidation of very long chain fatty acids in X-linked adrenoleukodystrophy is due to an impaired ability of peroxisomes to activate very long chain fatty acids

Wanders, R. J. A., van Roermund, C. W. T., van Wijland, M. J. A., Schutgens, R. B. H., van den BOSCH, H., Schram, A. W., & Tager, J. M. (1988) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(88)81140-9 · Cited by 157 · see citing works

Adrenoleukodystrophy

Rizzo, W. B., Watkins, P. A., Phillips, M. W., Cranin, D., Campbell, B. D., & Avigan, J. (1986) · Neurology · doi:10.1212/wnl.36.3.357 · Cited by 153 · see citing works

Individual variations in human meibomian lipid composition

Tiffany, J. M. (1978) · Experimental Eye Research · doi:10.1016/0014-4835(78)90164-1 · Cited by 151 · see citing works

Substrate specificities of rat liver peroxisomal acyl-CoA oxidases: palmitoyl-CoA oxidase (inducible acyl-CoA oxidase), pristanoyl-CoA oxidase (non-inducible acyl-CoA oxidase), and trihydroxycoprostanoyl-CoA oxidase.

Veldhoven, P. P. V., Vanhove, G. F., Asselberghs, S., Eyssen, H., & Mannaerts, G. P. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)88666-0 · Cited by 150 · see citing works

Association of protein kinase C with phospholipid vesicles

Bazzi, M. D., & Nelsestuen, G. L. (1987) · Biochemistry · doi:10.1021/bi00375a017 · Cited by 150 · see citing works

Phospholipid species containing long and very long polyenoic fatty acids remain with rhodopsin after hexane extraction of photoreceptor membranes

Aveldano, M. I. (1988) · Biochemistry · doi:10.1021/bi00404a024 · Cited by 149 · see citing works

3-Hydroxy-3-methylglutaryl coenzyme A reductase localization in rat liver peroxisomes and microsomes of control and cholestyramine-treated animals: quantitative biochemical and immunoelectron microscopical analyses.

Keller, G. A., Pazirandeh, M. P., & Krisans, S. K. (1986) · The Journal of Cell Biology · doi:10.1083/jcb.103.3.875 · Cited by 149 · see citing works

Very long chain (C24 to C36) polyenoic fatty acids of the n-3 and n-6 series in dipolyunsaturated phosphatidylcholines from bovine retina.

Aveldaño, M. I., & Sprecher, H. W. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)75768-8 · Cited by 145 · see citing works

A novel group of very long chain polyenoic fatty acids in dipolyunsaturated phosphatidylcholines from vertebrate retina

Aveldaño, M. I. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)75767-6 · Cited by 142 · see citing works

Acylglucosylceramides of pig epidermis: structure determination

Wertz, P. W., & Downing, D. T. (1983) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37949-9 · Cited by 142 · see citing works

Phorbol Ester Stimulates the Hydrolysis of Phosphatidylethanolamine in Leukemic HL-60, NIH 3T3, and Baby Hamster Kidney Cells

Kiss, Z., & Anderson, W. B. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)94213-4 · Cited by 140 · see citing works

Identity of Long-Chain Acyl-Coenzyme A Synthetase of Microsomes, Mitochondria, and Peroxisomes in Rat Liver1

Miyazawa, S., Hashimoto, T., & Yokota, S. (1985) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a135330 · Cited by 134 · see citing works

Infantile Refsum's disease (phytanic acid storage disease): a variant of Zellweger's syndrome?

Poulos, A., Sharp, P. C., & Whiting, M. J. (1984) · Clinical Genetics · doi:10.1111/j.1399-0004.1984.tb01107.x · Cited by 134 · see citing works

Fatty acid abnormality in adrenoleukodystrophy

Igarashi, M., Schaumburg, H. H., Powers, J., Kishimoto, Y., Koilodny, E., & Suzuki, K. (1976) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1976.tb04461.x-i1 · Cited by 134 · see citing works

Identification, isolation and characterization of epidermal lipids containing linoleic acid

BOWSER, P. A., Nugteren, D. H., White, R. J., Houtsmuller, U. M. T., & Prottey, C. (1985) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(85)90016-5 · Cited by 133 · see citing works

Correction of the Cutaneous Manifestations of Essential Fatty Acid Deficiency in Man by Application of Sunflower-Seed Oil to the Skin

Prottey, C., Hartop, P. J., & Press, M. (1975) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12510667 · Cited by 131 · see citing works

Rat peroxisomal 3-ketoacyl-CoA thiolase gene. Occurrence of two closely related but differentially regulated genes.

Hijikata, M., Wen, J., Osumi, T., & Hashimoto, T. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)39605-x · Cited by 130 · see citing works

Presence of three acyl-CoA oxidases in rat liver peroxisomes. An inducible fatty acyl-CoA oxidase, a noninducible fatty acyl-CoA oxidase, and a noninducible trihydroxycoprostanoyl-CoA oxidase.

Schepers, L., Veldhoven, P. P. V., Casteels, M., Eyssen, H., & Mannaerts, G. P. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)34113-4 · Cited by 130 · see citing works

A new dietary therapy for adrenoleukodystrophy: Biochemical and preliminary clinical results in 36 patients

Moser, A. B., Borel, J. S., Odone, A., Naidu, S., Cornblath, D., Sanders, D. B., & Moser, H. W. (1987) · Annals of Neurology · doi:10.1002/ana.410210305 · Cited by 130 · see citing works

Fatty acid composition of human brain sphingomyelins: normal variation with age and changes during myelin disorders

Ställberg-Stenhagen, S., & Svennerholm, L. (1965) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39652-8 · Cited by 129 · see citing works

Changes in lipid composition of the maturing rat testis

Davis, J., Bridges, R., & Coniglio, J. G. (1966) · Biochemical Journal · doi:10.1042/bj0980342 · Cited by 128 · see citing works

Metabolism of linoleic acid and other essential fatty acids in the epidermis of the rat

Nugteren, D. H., Christ-Hazelhof, E., van der Beek, A., & Houtsmuller, U. M. T. (1985) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(85)90017-7 · Cited by 127 · see citing works

The sphingolipid composition of bovine kidney cortex, medulla and papilla

Karlsson, K. ‐., Samuelsson, B. E., & Steen, G. O. (1973) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(73)90072-6 · Cited by 127 · see citing works

Brain lipids: I. Quantification and fatty acid composition of cerebroside sulfate in human cerebral gray and white matter

O’Brien, J. S., Fillerup, D. L., & Mead, J. F. (1964) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)40269-x · Cited by 121 · see citing works

Refsum's disease: characterization of the enzyme defect in cell culture

Herndon, J. H., Steinberg, D. H., Uhlendorf, B. W., et al. (1969) · Journal of Clinical Investigation · doi:10.1172/jci106058 · Cited by 118 · see citing works

Cholesterol synthesis in rat liver peroxisomes. Conversion of mevalonic acid to cholesterol.

Thompson, S. L., Burrows, R., Laub, R. J., & Krisans, S. K. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)45395-1 · Cited by 116 · see citing works

Phorbol diesters stimulate the accumulation of phosphatidate, phosphatidylethanol, and diacylglycerol in three cell types. Evidence for the indirect formation of phosphatidylcholine-derived diacylglycerol by a phospholipase D pathway and direct formation of diacylglycerol by a phospholipase C pathway.

Huang, C. F., & Cabot, M. C. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)77193-7 · Cited by 114 · see citing works

Sterol carrier protein 2 and fatty acid-binding protein. Separate and distinct physiological functions.

Scallen, T. J., Noland, B. J., Gavey, K. L., Bass, N. M., Ockner, R. K., Chanderbhan, R., & Vahouny, G. V. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)89132-3 · Cited by 111 · see citing works

Very-long-chain fatty acids from the animal and plant kingdoms

Řezanka, T. (1989) · Progress in Lipid Research · doi:10.1016/0163-7827(89)90011-8 · Cited by 110 · see citing works

Studies on the α Oxidation of Phytanic Acid by Rat Liver Mitochondria

Tsai, S. C., Avigan, J., & Steinberg, D. H. (1969) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)83452-4 · Cited by 108 · see citing works

Identification of the inflammatory cells in the central nervous system of patients with adrenoleukodystrophy

Griffin, D. E., Moser, H. W., Mendoza, Q. P., Moench, T. R., O'Toole, S., & Moser, A. B. (1985) · Annals of Neurology · doi:10.1002/ana.410180606 · Cited by 107 · see citing works

Arachidonoyl-CoA synthetase. Separation from nonspecific acyl-CoA synthetase and distribution in various cells and tissues.

Laposata, M., Reich, E. L., & Majerus, P. W. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)39141-x · Cited by 104 · see citing works

Acyl-Coenzyme A Synthetase and Fatty Acid Oxidation in Rat Liver Peroxisomes

Shindo, Y., & Hashimoto, T. (1978) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a132234 · Cited by 102 · see citing works

Severe deficiency of docosahexaenoic acid in peroxisomal disorders

Martínez, M. (1990) · Neurology · doi:10.1212/wnl.40.8.1292 · Cited by 102 · see citing works

Phospholipids in X-linked adrenoleukodystrophy white matter: Fatty acid abnormalities before the onset of demyelination

Theda, C., Moser, A. B., Powers, J. M., & Moser, H. W. (1992) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(92)90028-j · Cited by 99 · see citing works

Novel molecular species of sphingomyelin containing 2-hydroxylated polyenoic very-long-chain fatty acids in mammalian testes and spermatozoa.

Robinson, B. S., Johnson, D. W., & Poulos, A. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)46009-7 · Cited by 97 · see citing works

Adrenoleukodystrophy: Dietary oleic acid lowers hexacosanoate levels

Rizzo, W. B., Phillips, M. W., Dammann, A. L., Leshner, R. T., Jennings, S. S., Avigan, J., & Proud, V. K. (1987) · Annals of Neurology · doi:10.1002/ana.410210304 · Cited by 97 · see citing works

Very long chain fatty acid β-oxidation by rat liver mitochondria and peroxisomes

Singh, H., Derwas, N., & Poulos, A. (1987) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(87)90504-2 · Cited by 97 · see citing works

Abnormality of Long‐Chain Fatty Acids in Erythrocyte Membrane Sphingomyelin from Patients with Adrenoleukodystrophy

Tsuji, S., Suzuki, M., Ariga, T., Sekine, M., Kuriyama, M., & Miyatake, T. (1981) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1981.tb01698.x · Cited by 96 · see citing works

The occurrence of polyenoic fatty acids with greater than 22 carbon atoms in mammalian spermatozoa

Poulos, A., Sharp, P. C., Johnson, D., White, I., & Fellenberg, A. J. (1986) · Biochemical Journal · doi:10.1042/bj2400891 · Cited by 92 · see citing works

Oxidation of docosahexaenoic acid by rat liver microsomes.

VanRollins, M., BAKER, R. C., Sprecher, H. W., et al. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)91081-1 · Cited by 92 · see citing works

Complementation study of peroxisome-deficient disorders by immunofluorescence staining and characterization of fused cells

Yajima, S., Suzuki, Y., Shimozawa, N., et al. (1992) · Human Genetics · doi:10.1007/bf00219334 · Cited by 91 · see citing works

Neonatal adrenoleukodystrophy: clinical, pathologic, and biochemical delineation of a syndrome affecting both males and females.

Jaffe, R. B., Crumrine, P. K., Hashida, Y., & Moser, H. W. (1982) · PubMed Central · Cited by 89 · see citing works

Identification and purification of a peroxisomal branched chain fatty acyl-CoA oxidase.

Veldhoven, P. P. V., Vanhove, G. F., Vanhoutte, F., et al. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54283-6 · Cited by 88 · see citing works

Peroxisomal fatty acid beta-oxidation in relation to the accumulation of very long chain fatty acids in cultured skin fibroblasts from patients with Zellweger syndrome and other peroxisomal disorders.

Wanders, R. J. A., van Roermund, C. W. T., van Wijland, M. J. A., Schutgens, R. B. H., Heikoop, J. C., van den BOSCH, H., Schram, A. W., & Tager, J. M. (1987) · Journal of Clinical Investigation · doi:10.1172/jci113271 · Cited by 87 · see citing works

Infantile Refsum's disease: Biochemical findings suggesting multiple peroxisomal dysfunction

Poll‐The, B. T., Saudubray, J., de Baulny, H. O., Schutgens, R. B. H., Wanders, R. J. A., Schrakamp, G., van den BOSCH, H., Trijbels, J. M. F., Poulos, A., Moser, H. W., et al. (1985) · Journal of Inherited Metabolic Disease · doi:10.1007/bf01799455 · Cited by 86 · see citing works

The Prenatal Diagnosis of Adrenoleukodystrophy. Demonstration of Increased Hexacosanoic Acid Levels in Cultured Amniocytes and Fetal Adrenal Gland

Moser, H. W., Moser, A. B., Powers, J. M., Nitowsky, H. M., Schaumburg, H. H., Norum, R. A., & Migeon, B. R. (1982) · Pediatric Research · doi:10.1203/00006450-198203000-00002 · Cited by 86 · see citing works

Peroxisomal fatty acid oxidation in rat and human tissues. Effect of nutritional state, clofibrate treatment and postnatal development in the rat

Veerkamp, J. H., & van Moerkerk, H. T. B. (1986) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(86)90180-3 · Cited by 85 · see citing works

Lipid remodelling during epididymal maturation of rat spermatozoa. Enrichment in plasmenylcholines containing long-chain polyenoic fatty acids of the n-9 series

Aveldaño, M. I., Rotstein, N. P., & Vermouth, N. T. (1992) · Biochemical Journal · doi:10.1042/bj2830235 · Cited by 84 · see citing works

Dysmorphic syndrome with phytanic acid oxidase deficiency, abnormal very long chain fatty acids, and pipecolic acidemia: Studies in four children

Budden, S. S., Kennaway, N. G., Buist, N. R. M., et al. (1986) · The Journal of Pediatrics · doi:10.1016/s0022-3476(86)80765-x · Cited by 84 · see citing works

Brain gangliosides in adrenoleukodystrophy1

Igarashi, M., Belchjs, D., & Suzuki, K. (1976) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1976.tb01593.x · Cited by 81 · see citing works

Fatty Acyl-Coenzyme A Elongation in Brain of Normal and Quaking Mice

Goldberg, I., Shechter, I., & Bloch, K. (1973) · Science · doi:10.1126/science.182.4111.497 · Cited by 80 · see citing works

Adrenoleukodystrophy: evidence that abnormal very long chain fatty acids of brain cholesterol esters are of exogenous origin

Kishimoto, Y., Moser, H. W., Kawamura, N., Platt, M., Pallante, S. L., & Fenselau, C. (1980) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(80)91182-1 · Cited by 79 · see citing works

Untitled work

Menkes (1977) · doi:10.1212/wnl.27.10.928 · Cited by 78 · see citing works

Induction of fatty acid binding protein by peroxisome proliferators in primary hepatocyte cultures and its relationship to the induction of peroxisomal β-oxidation

Brandes, R., Kaikaus, R. M., Lysenko, N., Ockner, R. K., & Bass, N. M. (1990) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(90)90152-m · Cited by 78 · see citing works

Distinct long chain and very long chain fatty acyl CoA synthetases in rat liver peroxisomes and microsomes

Singh, H., & Poulos, A. (1988) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(88)90281-0 · Cited by 77 · see citing works

Effects of topical application of fatty acids

Houtsmuller, U. M. T., & van der Beek, A. (1981) · Progress in Lipid Research · doi:10.1016/0163-7827(81)90041-2 · Cited by 76 · see citing works

Essential Fatty Acids and Eicosanoids: Invited Papers from the Third International Congress

Eicosanoids, Sinclair, A. H., & Gibson, R. B. (1993) · Medical Entomology and Zoology · Cited by 75 · see citing works

Retroconversion and δ4 desaturation of docosatetraenoate (22:4(n−6)) and docosapentaenoate (22:5(n−3)) by human cells in culture

Rosenthal, M. D., Garcia, M. C., Jones, M. R., & Sprecher, H. W. (1991) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(91)90121-w · Cited by 75 · see citing works

Occurrence of unusual molecular species of sphingomyelin containing 28-34-carbon polyenoic fatty acids in ram spermatozoa

Poulos, A., Johnson, D. W., Beckman, K., White, I. G., & Easton, C. J. (1987) · Biochemical Journal · doi:10.1042/bj2480961 · Cited by 74 · see citing works

Structural organization of the gene for rat enoyl-CoA hydratase:3-hydroxyacyl-CoA dehydrogenase bifunctional enzyme.

Ishii, N., Hijikata, M., Osumi, T., & Hashimoto, T. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47541-2 · Cited by 73 · see citing works

Liver in the cerebro-hepato-renal syndrome: Defective bile acid synthesis and abnormal mitochondria

Mathis, R. K., Watkins, J. B., Szczepanik, P. A., & Lott, I. T. (1980) · Gastroenterology · doi:10.1016/0016-5085(80)90931-2 · Cited by 73 · see citing works

Increased Synthesis of Hexacosanoic Acid (C26 :0) by Cultured Skin Fibroblasts from Patients with Adrenoleukodystrophy (ALD) and Adrenomyeloneuropathy (AMN)1

TSUJI, S., SANO, T., ARIGA, T., & MIYATAKE, T. (1981) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a133578 · Cited by 73 · see citing works

Very long chain fatty acids in X‐linked adrenoleukodystrophy brain after treatment with Lorenzo's oil

Poulos, A., Gibson, R. A., Sharp, P. C., Beckman, K., & Grattan‐Smith, P. J. (1994) · Annals of Neurology · doi:10.1002/ana.410360509 · Cited by 72 · see citing works

Resistance to infection of the external eye: The role of tears

Selinger, D. S., Selinger, R. C. L., & Reed, W. P. (1979) · Survey of Ophthalmology · doi:10.1016/0039-6257(79)90145-0 · Cited by 70 · see citing works

Nervonic acid biosynthesis by erucyl-coa elongation in normal and quaking mouse brain microsomes. Elongation of other unsaturated fatty acyl-CoAs (mono and polyunsaturated)

Bourre, J. M., Daudu, O., & Baumann, N. (1976) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(76)90043-6 · Cited by 69 · see citing works

Cerebro-hepato-renal (Zellweger) syndrome, adrenoleukodystrophy, and Refsum's disease: Plasma changes and skin fibroblast phytanic acid oxidase

Poulos, A., Sharp, P. C., Fellenberg, A. J., et al. (1985) · Human Genetics · doi:10.1007/bf00273077 · Cited by 69 · see citing works

The occurrence of polyenoic very long chain fatty acids with greater than 32 carbon atoms in molecular species of phosphatidylcholine in normal and peroxisome-deficient (Zellweger's syndrome) brain

Poulos, A., Sharp, P. C., Johnson, D., & Easton, C. J. (1988) · Biochemical Journal · doi:10.1042/bj2530645 · Cited by 68 · see citing works

Neutrophil migration inhibitory properties of polyunsaturated fatty acids. The role of fatty acid structure, metabolism, and possible second messenger systems.

Ferrante, A., Goh, D. H. B., Harvey, D. P., Robinson, B. S., Hii, C. S. T., Bates, E. J., Hardy, S. J., Johnson, D. W., & Poulos, A. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117056 · Cited by 68 · see citing works

Effects of aging on the content, composition and synthesis of sphingomyelin in the central nervous system

Giusto, N. M., Roque, M. E., & de Boschero, M. G. I. (1992) · Lipids · doi:10.1007/bf02535859 · Cited by 68 · see citing works

Topographical localization of peroxisomal acyl-CoA ligases: differential localization of palmitoyl-CoA and lignoceroyl-CoA ligases

Lazo, O., Contreras, M., & Singh, I. (1990) · Biochemistry · doi:10.1021/bi00468a027 · Cited by 68 · see citing works

Patterns of Refsum's disease. Phytanic acid oxidase deficiency.

Poulos, A., Pollard, A. C., Mitchell, J. D., Wise, G., & Mortimer, G. (1984) · Archives of Disease in Childhood · doi:10.1136/adc.59.3.222 · Cited by 67 · see citing works

Polyunsaturated fatty acid changes suggesting a new enzymatic defect in Zellweger Syndrome

Martínez, M. (1989) · Lipids · doi:10.1007/bf02535160 · Cited by 66 · see citing works

Formic acid is a product of the α-oxidation of fatty acids by human skin fibroblasts: deficiency of formic acid production in peroxisome-deficient fibroblasts

Poulos, A., Sharp, P. C., Singh, H., et al. (1993) · Biochemical Journal · doi:10.1042/bj2920457 · Cited by 65 · see citing works

Thermal lateral phase separations in bovine retinal rod outer segment membranes and phospholipids as evidenced by parinaric acid fluorescence polarization and energy transfer.

Sklar, L. A., Miljanich, G. P., Bursten, S. L., et al. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)83555-x · Cited by 65 · see citing works

Detection of a homologous series of C26-C38 polyenoic fatty acids in the brain of patients without peroxisomes (Zellweger's syndrome)

Poulos, A., Sharp, P. C., Singh, H., Johnson, D., Fellenberg, A. J., & Pollard, A. C. (1986) · Biochemical Journal · doi:10.1042/bj2350607 · Cited by 64 · see citing works

Accumulation and defective β‐oxidation of very long chain fatty acids in Zellweger's syndrome, adrenoleukodystrophy and Refsum's disease variants

Poulos, A., Singh, H., Paton, B. C., Sharp, P. C., & Derwas, N. (1986) · Clinical Genetics · doi:10.1111/j.1399-0004.1986.tb00511.x · Cited by 63 · see citing works

Identification by combined gas chromatography-mass spectrometry of constituent long-chain fatty acids and alcohols from the meibomian glands of the rat and a comparison with human meibomian lipids

Harvey, D. J., Tiffany, J. M., DUERDEN, J. M., Pandher, K. S., & Mengher, L. S. (1987) · Journal of Chromatography B Biomedical Sciences and Applications · doi:10.1016/0378-4347(87)80051-8 · Cited by 62 · see citing works

Pathology of hepatic peroxisomes and mitochondria in patients with peroxisomal disorders

Hughes, J. L., Poulos, A., Robertson, E. F., Chow, C. W., Sheffield, L. J., Christodoulou, J., & Carter, R. F. (1990) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/bf01678985 · Cited by 61 · see citing works

Postnatal Development and Isolation of Peroxisomes from Brain

Lazo, O., Singh, A. K., & Singh, I. (1991) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1991.tb11431.x · Cited by 61 · see citing works

Fatty Acid Composition of Human Myelin Proteolipid Protein in Peroxisomal Disorders

Bizzozero, O. A., Zuñiga, G., & Lees, M. B. (1991) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1991.tb02003.x · Cited by 61 · see citing works

Regulation of bile-acid synthesis. Role of sterol carrier protein2 in the biosynthesis of 7α-hydroxycholesterol

Seltman, H. J., Diven, W. F., Rizk, M., et al. (1985) · Biochemical Journal · doi:10.1042/bj2300019 · Cited by 61 · see citing works

Fatty Acid Elongation Activity in Fibroblasts from Patients with Adrenoleukodystrophy (ALD)1

Tsuji, S., Ohno, T., Miyatake, T., et al. (1984) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a134942 · Cited by 60 · see citing works

A novel ecto-phosphatidic acid phosphohydrolase activity mediates activation of neutrophil superoxide generation by exogenous phosphatidic acid.

Perry, D. K., Stevens, V. L., Widlanski, T. S., et al. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)74392-0 · Cited by 59 · see citing works

Polyunsaturated fatty acids increase neutrophil adherence and integrin receptor expression

Bates, E. J., Ferrante, A., Harvey, D. R., et al. (1993) · Journal of Leukocyte Biology · doi:10.1002/jlb.53.4.420 · Cited by 59 · see citing works

Molecular Species of Phosphatidylcholine Containing Very Long Chain Fatty Acids in Human Brain: Enrichment in X‐Linked Adrenoleukodystrophy Brain and Diseases of Peroxisome Biogenesis Brain

Sharp, P. C., Johnson, D., & Poulos, A. (1991) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1991.tb02558.x · Cited by 58 · see citing works

Lipid-induced ordered conformation of some peptide hormones and bioactive oligopeptides: predominance of the helix over the .beta.-form

Wu, C. S., Hachimori, A., & Yang, J. T. (1982) · Biochemistry · doi:10.1021/bi00262a007 · Cited by 58 · see citing works

Unique molecular species of phosphatidylcholine containing very-long-chain (C24-C38) polyenoic fatty acids in rat brain

Robinson, B. S., Johnson, D. W., & Poulos, A. (1990) · Biochemical Journal · doi:10.1042/bj2650763 · Cited by 57 · see citing works

Effect of 22-32 carbon n-3 polyunsaturated fatty acids on superoxide production in human neutrophils: synergism of docosahexaenoic acid with f-met-leu-phe and phorbol ester.

Poulos, A., Robinson, B. S., Ferrante, A., Harvey, D. P., Hardy, S. J., & Murray, A. W. (1991) · PubMed Central · Cited by 57 · see citing works

Adrenoleukodystrophy: effects of dietary restriction of very long chain fatty acids and of administration of carnitine and clofibrate on clinical status and plasma fatty acids.

Brown, F. R., Duyn, M. A. V., Moser, A. B., Schulman, J. D., Rizzo, W. B., Snyder, R. D., Murphy, J. V., Kamoshita, S., Migeon, C. J., & Moser, H. W. (1982) · PubMed · Cited by 56 · see citing works

Metabolism of acetyl-CoA by isolated peroxisomal fractions: formation of acetate and acetoacetyl-CoA.

HOVIK, R., Brodal, B., Bartlett, K., et al. (1991) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41996-0 · Cited by 56 · see citing works

Phytanic acid alpha-oxidation in rat liver. Requirement of cytosolic factor.

Muralidharan, V. B., & Kishimoto, Y. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)90650-2 · Cited by 55 · see citing works

The role of peroxisomes in mammalian cellular metabolism

Lazarow, P. B. (1987) · Journal of Inherited Metabolic Disease · doi:10.1007/bf01812843 · Cited by 55 · see citing works

Visual evoked potentials in adrenolukodystrophy: A trial with glycerol trioleate and Lorenzo oil

Kaplan, P. W., Tusa, R. J., Shankroff, J., Heller, J., & Moser, H. W. (1993) · Annals of Neurology · doi:10.1002/ana.410340212 · Cited by 55 · see citing works

Abnormal messenger RNA expression and a missense mutation in patients with X-linked adrenoleukodystrophy

Cartier, N., Sarde, C.-O., Douar, A.-M., Mosser, J., Mandel, J.-L., & Aubourg, P. (1993) · Human Molecular Genetics · doi:10.1093/hmg/2.11.1949 · Cited by 55 · see citing works

The Biosynthesis of Δ9,12,15,18-Tetracosatetraenoic and of Δ6,9,12,15,18-Tetracosapentaenoic Acids by Rat Testes

Bridges, R. B., & Coniglio, J. G. (1970) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)63420-9 · Cited by 53 · see citing works

Effect of exogenous fatty acids with greater than 22 carbon atoms (very long chain fatty acids) on superoxide production by human neutrophils.

Hardy, S. J., Ferrante, A., Poulos, A., Robinson, B. S., Johnson, D. W., & Murray, A. W. (1994) · The Journal of Immunology · doi:10.4049/jimmunol.153.4.1754 · Cited by 53 · see citing works

The meibomian lipids of the rabbit. I. Overall composition

Tiffany, J. M. (1979) · Experimental Eye Research · doi:10.1016/0014-4835(79)90084-8 · Cited by 53 · see citing works

The design of a diet restricted in saturated very long-chain fatty acids: therapeutic application in adrenoleukodystrophy

Duyn, M. A. V., Moser, A. E., Brown, F. R., Sacktor, N., Liu, A., & Moser, H. W. (1984) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/40.2.277 · Cited by 53 · see citing works

Identification of meibomian gland lipids by gas chromatography—mass spectrometry: application to the meibomian lipids of the mouse

Harvey, D. J., & Tiffany, J. M. (1984) · Journal of Chromatography A · doi:10.1016/s0021-9673(01)89187-1 · Cited by 50 · see citing works

Topography of very-long-chain-fatty-acid-activating activity in peroxisomes from rat liver

Lageweg, W., Tager, J. M., & Wanders, R. J. A. (1991) · Biochemical Journal · doi:10.1042/bj2760053 · Cited by 50 · see citing works

THE FATTY ACID COMPOSITION OF SPHINGOLIPIDS FROM BOVINE CNS AXONS AND MYELIN1

DeVries, G. H., & Norton, W. T. (1974) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1974.tb11587.x · Cited by 49 · see citing works

Activation of protein kinase C by short chain phosphatidylcholines.

Walker, J. M., & Sando, J. J. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)68816-7 · Cited by 49 · see citing works

Phorbol ester-stimulated hydrolysis of phosphatidylcholine and phosphatidylethanolamine by phospholipase D in HeLa cells. Evidence that the basal turnover of phosphoglycerides does not involve phospholipase D.

Hii, C. S. T., Edwards, Y. S., & Murray, A. W. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54915-2 · Cited by 48 · see citing works

Long and very long chain polyunsaturated fatty acids of the n-6 series in rat seminiferous tubules. Active desaturation of 24:4n-6 to 24:5n-6 and concomitant formation of odd and even chain tetraenoic and pentaenoic fatty acids up to C32

Aveldaño, M. I., Robinson, B. S., Johnson, D. W., & Poulos, A. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)50251-4 · Cited by 47 · see citing works

Phorbol-12-myristate-13-acetate activation of phospholipase D in human neutrophils leads to the production of phosphatides and diglycerides

Mullmann, T. J., Siegel, M. I., Egan, R. W., et al. (1990) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(90)90520-w · Cited by 47 · see citing works

A comparative study of stearic and lignoceric acid oxidation by human skin fibroblasts

Singh, H., & Poulos, A. (1986) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(86)90714-9 · Cited by 47 · see citing works

β-oxidation of very-long-chain fatty acids and their coenzyme A derivatives by human skin fibroblasts

Singh, H., Derwas, N., & Poulos, A. (1987) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(87)90133-0 · Cited by 46 · see citing works

Peroxisomal beta-oxidation of branched chain fatty acids in rat liver. Evidence that carnitine palmitoyltransferase I prevents transport of branched chain fatty acids into mitochondria

Singh, H., Beckman, K., & Poulos, A. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)36911-9 · Cited by 45 · see citing works

The neutrophil respiratory burst

Hardy, S. J., Robinson, B. S., Poulos, A., Harvey, D. P., Ferrante, A., & Murray, A. W. (1991) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1991.tb16084.x · Cited by 45 · see citing works

Abnormalities in Cultured Muscle and Peripheral Nerve of a Patient with Adrenomyeloneuropathy

Askanas, V., McLaughlin, J., Engel, W. K., & Adornato, B. T. (1979) · New England Journal of Medicine · doi:10.1056/nejm197909133011105 · Cited by 45 · see citing works

Accumulation of very long chain fatty acids is common to 3 variants of adrenoleukodystrophy (ALD)

Molzer, B., Bernheimer, H., Budka, H., Pilz, P. K. D., & Toifl, K. (1981) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(81)90108-8 · Cited by 42 · see citing works

Metabolism of arachidonate in rat testis: Characterization of 26–30 carbon polyenoic acids

Grogan, W. M. (1984) · Lipids · doi:10.1007/bf02534785 · Cited by 40 · see citing works

Conclusive evidence that very-long-chain fatty acids are oxidized exclusively in peroxisomes in human skin fibroblasts

Jakobs, B. S., & Wanders, R. J. A. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(91)90967-c · Cited by 39 · see citing works

Structure and lipid distribution of polyenoic very-long-chain fatty acids in the brain of peroxisome-deficient patients (Zellweger syndrome)

Sharp, P. C., Poulos, A., Fellenberg, A. J., & Johnson, D. (1987) · Biochemical Journal · doi:10.1042/bj2480061 · Cited by 38 · see citing works

In Vitro Activation of Rat Brain Protein Kinase C by Polyenoic Very‐Long‐Chain Fatty Acids

Hardy, S. J., Ferrante, A., Robinson, B. S., et al. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.62041546.x · Cited by 38 · see citing works

Mitochondrial and Peroxisomal β‐Oxidation of Stearic and Lignoceric Acids by Rat Brain

Singh, H., Usher, S., & Poulos, A. (1989) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1989.tb09235.x · Cited by 37 · see citing works

Synthesis of very long chain (up to 36 carbon) tetra, penta and hexaenoic fatty acids in retina

Rotstein, N. P., & Aveldaño, M. I. (1988) · Biochemical Journal · doi:10.1042/bj2490191 · Cited by 36 · see citing works

Role of tears in maintaining corneal integrity.

Tiffany, J. M., & Aj, B. (1978) · PubMed · Cited by 35 · see citing works

Total and peroxisomal oxidation of various saturated and unsaturated fatty acids in rat liver, heart and m. quadriceps

Reubsaet, F. A. G., Veerkamp, J. H., Trijbels, J. M. F., et al. (1989) · Lipids · doi:10.1007/bf02544539 · Cited by 35 · see citing works

Physiological significance of fatty acid elongation system in adrenoleukodystrophy

Koike, R., Tsuji, S., Ohno, T., Suzuki, Y., Orii, T., & Miyatake, T. (1991) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(91)90163-2 · Cited by 35 · see citing works

A bifunctional protein with deficient enzymic activity: Identification of a new peroxisomal disorder using novel methods to measure the peroxisomal β‐oxidation enzyme activities

Wanders, R. J. A., van Roermund, C. W. T., Schelen, A. M., et al. (1990) · Journal of Inherited Metabolic Disease · doi:10.1007/bf01799399 · Cited by 34 · see citing works

Adrenoleukodystrophy brain cholesteryl esters and other neutral lipids

Ramsey, R. B., Banik, N. L., & Davison, A. N. (1979) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(79)90203-x · Cited by 34 · see citing works

Human vascular endothelial cells synthesize and release 24- and 26-carbon polyunsaturated fatty acids

Rosenthal, M. D., & Hill, J. R. (1984) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(84)90063-8 · Cited by 34 · see citing works

The presence of hydroxy fatty acids in sphingomyelins of bovine rennet stomach

Karlsson, K., Nilsson, K. B., Samuelsson, B. E., et al. (1969) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(69)90239-2 · Cited by 33 · see citing works

Lipid metabolism in Zellweger's syndrome

Poulos, A. (1989) · Progress in Lipid Research · doi:10.1016/0163-7827(89)90006-4 · Cited by 32 · see citing works

Biosynthesis of long‐chain polyenoic acids from arachidonic acid in cultures of enriched spermatocytes and spermatids from mouse testis

Grogan, W. M., & Huth, E. G. (1983) · Lipids · doi:10.1007/bf02534702 · Cited by 32 · see citing works

Proteolytic digestion patterns of spectrin subunits

Calvert, R. A., & Gratzer, W. B. (1978) · FEBS Letters · doi:10.1016/0014-5793(78)80572-9 · Cited by 32 · see citing works

Metabolism of [17, 18-3H2]hexacosanoic acid and [15,16-3H2]lignoceric acid in cultured skin fibroblasts from patients with adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN)

Tsuji, S., Sano-Kawamura, T., Ariga, T., & Miyatake, T. (1985) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(85)90074-7 · Cited by 31 · see citing works

Complementation Analysis of Patients with Intact Peroxisomes and Impaired Peroxisomal β-Oxidation

McGuinness, M. C., Moser, A. B., Poll‐The, B. T., et al. (1993) · Biochemical Medicine and Metabolic Biology · doi:10.1006/bmmb.1993.1025 · Cited by 30 · see citing works

Detection of adrenoleukodystrophy by increased C26:0 fatty acid levels in leukocytes

Molzer, B., Bernheimer, H., Heller, R., et al. (1982) · Clinica Chimica Acta · doi:10.1016/0009-8981(82)90260-1 · Cited by 30 · see citing works

Alcohols selectively stimulate phospholipase D‐mediated hydrolysis of phosphatidylethanolamine in NIH 3T3 cells

Kiss, Z., & Anderson, W. B. (1989) · FEBS Letters · doi:10.1016/0014-5793(89)81782-x · Cited by 30 · see citing works

Very Long-Chain Fatty Acids in Peroxisomal Disease

Poulos, A., Beckman, K., Johnson, D. W., Paton, B. C., Robinson, B. S., Sharp, P. C., Usher, S., & Singh, H. (1992) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-3426-6_30 · Cited by 29 · see citing works

The HLA System in Italy

Olivetti, E., Rendine, S., Cappello, N., et al. (1986) · Human Heredity · doi:10.1159/000153660 · Cited by 29 · see citing works

Lipid peroxidation of membrane phospholipids generates hydroxy-alkenals and oxidized phospholipids active in physiological and/or pathological conditions

Catalá, A. (2009) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2008.09.004 · Cited by 745 · see citing works

Identification and expression of mammalian long‐chain PUFA elongation enzymes

Leonard, A. E., Kelder, B., Bobik, E. G., Chuang, L., Lewis, C. J., Kopchick, J. J., Mukerji, P., & Huang, Y. (2002) · Lipids · doi:10.1007/s11745-002-0955-6 · Cited by 209 · see citing works

Interactions of a very long chain fatty acid with model membranes and serum albumin. Implications for the pathogenesis of adrenoleukodystrophy.

Ho, J. K., Moser, H., Kishimoto, Y., & Hamilton, J. A. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118182 · Cited by 199 · see citing works

Responses of<i>Nannochloropsis oceanica</i>IMET1 to Long-Term Nitrogen Starvation and Recovery

Dong, H.-P., Williams, E., Wang, D.-Z., Xie, Z.-X., Hsia, R.-C., Jenck, A., Halden, R., Li, J., Chen, F., & Place, A. R. (2013) · Plant Physiology · doi:10.1104/pp.113.214320 · Cited by 173 · see citing works

Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein

Agbaga, M.-P., Mandal, M. N. A., & Anderson, R. E. (2010) · Journal of Lipid Research · doi:10.1194/jlr.r005025 · Cited by 167 · see citing works

Lipid metabolism in peroxisomes in relation to human disease

Wanders, R. J. A., & Tager, J. M. (1998) · Molecular Aspects of Medicine · doi:10.1016/s0098-2997(98)00003-x · Cited by 122 · see citing works

Identification and biophysical characterization of a very-long-chain-fatty-acid-substituted phosphatidylinositol in yeast subcellular membranes

SCHNEITER, R., BRÜGGER, B., AMANN, C. M., PRESTWICH, G. D., EPAND, R. F., ZELLNIG, G., WIELAND, F. T., & EPAND, R. M. (2004) · Biochemical Journal · doi:10.1042/bj20040320 · Cited by 98 · see citing works

Alleviation of reactive oxygen species enhances PUFA accumulation in Schizochytrium sp. through regulating genes involved in lipid metabolism

Zhang, S., He, Y., Sen, B., Chen, X., Xie, Y., Keasling, J. D., & Wang, G. (2018) · Metabolic Engineering Communications · doi:10.1016/j.meteno.2018.03.002 · Cited by 90 · see citing works

Influence of very-long-chain polyunsaturated fatty acids on membrane structure and dynamics

Cheng, V., Rallabandi, R., Gorusupudi, A., Lucas, S., Rognon, G., Bernstein, P. S., Rainier, J. D., & Conboy, J. C. (2022) · Biophysical Journal · doi:10.1016/j.bpj.2022.06.015 · Cited by 14 · see citing works

Gene expression of peroxisomal β-oxidation enzymes in rat brain

Knoll, A., Sargueil, F., Salles, J., Cassagne, C., & Garbay, B. (1999) · Molecular Brain Research · doi:10.1016/s0169-328x(99)00252-1 · Cited by 9 · see citing works

Dietary fish oil enriched in very-long-chain polyunsaturated fatty acid reduces cardiometabolic risk factors and improves retinal function

Yang, Z.-H., Gorusupudi, A., Lydic, T. A., Mondal, A. K., Sato, S., Yamazaki, I., Yamaguchi, H., Tang, J., Rojulpote, K. V., Lin, A. B., et al. (2023) · iScience · doi:10.1016/j.isci.2023.108411 · Cited by 9 · see citing works

Role of ALDP (ABCD1) and Mitochondria in X-Linked Adrenoleukodystrophy

McGuinness, M. C., Lu, J.-F., Zhang, H.-P., Dong, G.-X., Heinzer, A. K., Watkins, P. A., Powers, J., & Smith, K. D. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.2.744-753.2003 · Cited by 147 · see citing works

Peroxisomal Very Long Chain Fatty Acid β-Oxidation Activity Is Determined by the Level of Adrenodeukodystrophy Protein (ALDP) Expression

Braiterman, L. T., Watkins, P. A., Moser, A. B., & Smith, K. D. (1999) · Molecular Genetics and Metabolism · doi:10.1006/mgme.1998.2789 · Cited by 19 · see citing works

Juvenile onset globoid cell leukodystrophy masquerading as XL‐adrenoleukodystrophy

Srinivasan, J., Coleman, L. T., & Kornberg, A. J. (2008) · Journal of Paediatrics and Child Health · doi:10.1111/j.1440-1754.2008.01340.x · Cited by 5 · see citing works

Peroxisomal Heat Generation and Possible Relationship With Peroxisomal Disorders

Petroni, A. (2013) · Advances in Biochemistry · doi:10.11648/j.ab.20130101.12 · Cited by 2 · see citing works

Peroxisomal Defects in Neonatal-Onset and X-Linked Adrenoleukodystrophies

Goldfischer, S. L., Collins, J. C., Rapin, I., Coltoff-Schiller, B., Chang, C., Nigro, M. A., Black, V. H., Javitt, N. B., Moser, H. W., & Lazarow, P. B. (1985) · Science · doi:10.1126/science.3964959 · Cited by 151 · see citing works