The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
The cerebrospinal fluid: regulator of neurogenesis, behavior, and beyond
Open accessAbstract
The cerebrospinal fluid (CSF) has attracted renewed interest as an active signaling milieu that regulates brain development, homeostasis, and disease. Advances in proteomics research have enabled an improved characterization of the CSF from development through adulthood, and key neurogenic signaling pathways that are transmitted via the CSF are now being elucidated. Due to its immediate contact with neural stem cells in the developing and adult brain, the CSF’s ability to swiftly distribute signals across vast distances in the central nervous system is opening avenues to novel and exciting therapeutic approaches. In this review, we will discuss the development of the choroid plexus-CSF system, and review the current literature on how the CSF actively regulates mammalian brain development, behavior, and responses to traumatic brain injury.
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Narcolepsy in orexin Knockout Mice
Chemelli, R. M., Willie, J. T., Sinton, C. M., Elmquist, J. K., Scammell, T., Lee, C., Richardson, J. A., Williams, S. C., Xiong, Y., Kisanuki, Y., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)81973-x · Cited by 3,095
A decade of molecular biology of retinoic acid receptors
Chambon, P. (1996) · The FASEB Journal · doi:10.1096/fasebj.10.9.8801176 · Cited by 2,889
Intranasal delivery of biologics to the central nervous system
Lochhead, J. J., & Thorne, R. G. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.11.002 · Cited by 1,214
Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons
Woods, S. C., Lotter, E. C., McKay, L. D., & Porte, D. (1979) · Nature · doi:10.1038/282503a0 · Cited by 1,114
Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans
Schwartz, M. W., Peskind, E., Raskind, M., Boyko, E. J., & Porte, D. (1996) · Nature Medicine · doi:10.1038/nm0596-589 · Cited by 1,014
Chemical characterization of a family of brain lipids that induce sleep
Cravatt, B. F., Prospero-Garcia, O., Siuzdak, G., Gilula, N. B., Henriksen, S. J., Boger, D. L., & Lerner, R. A. (1995) · Science · doi:10.1126/science.7770779 · Cited by 620
Retinoic acid from the meninges regulates cortical neuron generation.
Siegenthaler, J. A., Ashique, A. M., Zarbalis, K., Patterson, K. P., Hecht, J. H., Kane, M. A., Folias, A. E., Choe, Y., May, S. R., Kume, T., et al. (2009) · Cell · doi:10.1016/j.cell.2009.10.004 · Cited by 402
Insulin in the Cerebrospinal Fluid
MARGOLIS, R. U., & ALTSZULER, N. (1967) · Nature · doi:10.1038/2151375a0 · Cited by 278
One hundred years of positional information.
Wolpert, L. (1996) · Trends in Genetics · doi:10.1016/s0168-9525(96)80019-9 · Cited by 265
Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation
Awatramani, R., Soriano, P., Rodriguez, C., Mai, J. J., & Dymecki, S. M. (2003) · Nature Genetics · doi:10.1038/ng1228 · Cited by 215
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Urbán, N., Blomfield, I. M., & Guillemot, F. (2019) · Neuron · doi:10.1016/j.neuron.2019.09.026 · Cited by 373
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Dimou, L., & Götz, M. (2014) · Physiological Reviews · doi:10.1152/physrev.00036.2013 · Cited by 264
Adult neural stem cells and their niche: a dynamic duo during homeostasis, regeneration, and aging
Silva-Vargas, V., Crouch, E. E., & Doetsch, F. (2013) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.09.004 · Cited by 157
Anatomy and function of the vertebral column lymphatic network in mice
Jacob, L., Boisserand, L. S. B., Geraldo, L. H. M., de Brito Neto, J., Mathivet, T., Antila, S., Barka, B., Xu, Y., Thomas, J.-M., Pestel, J., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12568-w · Cited by 144
Metadata
- Authors
- Zappaterra, M. W., & Lehtinen, M. K.
- Venue
- Cellular and Molecular Life Sciences
- Published
- 2012-03-14
- Volume
- 69
- Issue
- 17
- Pages
- 2863-2878
- ISSN
- 1420-682X (ISSN-L)
- 1420-9071
- OpenAlex
- W2077824751
- Cited by
- 185
- References
- 12
- FWCI
- 5.77
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.