Neural stem cells: origin, heterogeneity and regulation in the adult mammalian brain

Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System

Reynolds, B. A., & Weiss, S. (1992) · Science · doi:10.1126/science.1553558 · Cited by 5,413 · see citing works

Subventricular zone astrocytes are neural stem cells in the adult mammalian brain

Doetsch, F., Caillé, I., Lim, D. A., García-Verdugo, J. M., & Alvarez-Buylla, A. (1999) · Cell · doi:10.1016/s0092-8674(00)80783-7 · Cited by 3,898 · see citing works

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

Kopan, R., & Ilagan, M. X. G. (2009) · Cell · doi:10.1016/j.cell.2009.03.045 · Cited by 3,631 · see citing works

Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats

Altman, J., & Das, G. D. (1965) · Journal of Comparative Neurology · doi:10.1002/cne.901240303 · Cited by 3,592 · see citing works

Functional neurogenesis in the adult hippocampus

van Praag, H., Schinder, A. F., Christie, B. R., Toni, N., Palmer, T. D., & Gage, F. H. (2002) · Nature · doi:10.1038/4151030a · Cited by 2,853 · see citing works

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions

Ming, G.-L., & Song, H. (2011) · Neuron · doi:10.1016/j.neuron.2011.05.001 · Cited by 2,651 · see citing works

The Glial Nature of Embryonic and Adult Neural Stem Cells

Kriegstein, A., & Alvarez-Buylla, A. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.051508.135600 · Cited by 2,475 · see citing works

Long-Distance Neuronal Migration in the Adult Mammalian Brain

Lois, C., & Álvarez-Buylla, A. (1994) · Science · doi:10.1126/science.8178174 · Cited by 2,331 · see citing works

Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases

Noctor, S. C., Martínez-Cerdeño, V., Ivic, L., & Kriegstein, A. R. (2004) · Nature Neuroscience · doi:10.1038/nn1172 · Cited by 2,229 · see citing works

Neurons derived from radial glial cells establish radial units in neocortex

Noctor, S. C., Flint, A. C., Weissman, T. A., Dammerman, R. S., & Kriegstein, A. R. (2001) · Nature · doi:10.1038/35055553 · Cited by 2,016 · see citing works

Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells

Snippert, H. J., van der Flier, L. G., Sato, T., van Es, J. H., van den Born, M., Kroon-Veenboer, C., Barker, N., Klein, A. M., van Rheenen, J., Simons, B. D., et al. (2010) · Cell · doi:10.1016/j.cell.2010.09.016 · Cited by 1,951 · see citing works

Cellular Composition and Three-Dimensional Organization of the Subventricular Germinal Zone in the Adult Mammalian Brain

Doetsch, F. K., García‐Verdugo, J. M., & Álvarez-Buylla, A. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-13-05046.1997 · Cited by 1,909 · see citing works

Identification of a Neural Stem Cell in the Adult Mammalian Central Nervous System

Johansson, C. B., Momma, S., Clarke, D. L., Risling, M., Lendahl, U., & Frisén, J. (1999) · Cell · doi:10.1016/s0092-8674(00)80956-3 · Cited by 1,875 · see citing works

Dynamics of hippocampal neurogenesis in adult humans

Spalding, K. L., Bergmann, O., Alkass, K., Bernard, S., Salehpour, M., Huttner, H. B., Boström, E., Westerlund, I., Vial, C., Buchholz, B. A., et al. (2013) · Cell · doi:10.1016/j.cell.2013.05.002 · Cited by 1,841 · see citing works

Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone

Luskin, M. B. (1993) · Neuron · doi:10.1016/0896-6273(93)90281-u · Cited by 1,803 · see citing works

Enriched environments, experience-dependent plasticity and disorders of the nervous system

Nithianantharajah, J., & Hannan, A. J. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1970 · Cited by 1,771 · see citing works

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

Villeda, S. A., Luo, J., Mosher, K. I., Zou, B., Britschgi, M., Bieri, G., Stan, T. M., Fainberg, N., Ding, Z., Eggel, A., et al. (2011) · Nature · doi:10.1038/nature10357 · Cited by 1,763 · see citing works

Astrocytes give rise to new neurons in the adult mammalian hippocampus

Seri, B., Garcı́a-Verdugo, J. M., McEwen, B. S., & Alvarez-Buylla, A. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-18-07153.2001 · Cited by 1,495 · see citing works

Vertebrate Smoothened functions at the primary cilium

Corbit, K. C., Aanstad, P., Singla, V., Norman, A. R., Stainier, D. Y. R., & Reiter, J. F. (2005) · Nature · doi:10.1038/nature04117 · Cited by 1,481 · see citing works

Patched1 Regulates Hedgehog Signaling at the Primary Cilium

Rohatgi, R., Milenkovic, L., & Scott, M. P. (2007) · Science · doi:10.1126/science.1139740 · Cited by 1,426 · see citing works

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

Sorrells, S. F., Paredes, M. F., Cebrian-Silla, A., Sandoval, K., Qi, D., Kelley, K. W., James, D., Mayer, S., Chang, J., Auguste, K. I., et al. (2018) · Nature · doi:10.1038/nature25975 · Cited by 1,422 · see citing works

Milestones of neuronal development in the adult hippocampus

Kempermann, G., Jessberger, S., Steiner, B., & Kronenberg, G. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.05.013 · Cited by 1,411 · see citing works

Neural stem cells in the adult mammalian forebrain: A relatively quiescent subpopulation of subependymal cells

Morshead, C. M., Reynolds, B. A., Craig, C. G., McBurney, M. W., Staines, W. A., Morassutti, D., Weiss, S., & van der Kooy, D. (1994) · Neuron · doi:10.1016/0896-6273(94)90046-9 · Cited by 1,403 · see citing works

Neurogenic radial glia in the outer subventricular zone of human neocortex

Hansen, D. V., Lui, J. H., Parker, P. R. L., & Kriegstein, A. R. (2010) · Nature · doi:10.1038/nature08845 · Cited by 1,388 · see citing works

Human Hippocampal Neurogenesis Persists throughout Aging

Boldrini, M., Fulmore, C. A., Tartt, A. N., Simeon, L. R., Pavlova, I., Poposka, V., Rosoklija, G. B., Stankov, A., Arango, V., Dwork, A. J., et al. (2018) · Cell Stem Cell · doi:10.1016/j.stem.2018.03.015 · Cited by 1,345 · see citing works

Chain Migration of Neuronal Precursors

Lois, C., García-Verdugo, J.-M., & Alvarez-Buylla, A. (1996) · Science · doi:10.1126/science.271.5251.978 · Cited by 1,331 · see citing works

Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage

Kessaris, N., Fogarty, M., Iannarelli, P., Grist, M., Wegner, M., & Richardson, W. D. (2006) · Nature Neuroscience · doi:10.1038/nn1620 · Cited by 1,195 · see citing works

Adult Neurogenesis in the Hippocampus: From Stem Cells to Behavior

Gonçalves, J. T., Schafer, S. T., & Gage, F. H. (2016) · Cell · doi:10.1016/j.cell.2016.10.021 · Cited by 1,122 · see citing works

Noggin Antagonizes BMP Signaling to Create a Niche for Adult Neurogenesis

Lim, D. A., Tramontin, A. D., Trevejo, J., Herrera, D. G., García‐Verdugo, J. M., & Álvarez-Buylla, A. (2000) · Neuron · doi:10.1016/s0896-6273(00)00148-3 · Cited by 1,090 · see citing works

Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain

Imayoshi, I., Sakamoto, M., Ohtsuka, T., Takao, K., Miyakawa, T., Yamaguchi, M., Mori, K., Ikeda, T., Itohara, S., & Kageyama, R. (2008) · Nature Neuroscience · doi:10.1038/nn.2185 · Cited by 1,054 · see citing works

Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors

Katsimpardi, L., Litterman, N. K., Schein, P. A., Miller, C. M., Loffredo, F. S., Wojtkiewicz, G. R., Chen, J. W., Lee, R. T., Wagers, A. J., & Rubin, L. L. (2014) · Science · doi:10.1126/science.1251141 · Cited by 1,037 · see citing works

A specialized vascular niche for adult neural stem cells

Tavazoie, M., Van der Veken, L., Silva-Vargas, V., Louissaint, M., Colonna, L., Zaidi, B., Garcia-Verdugo, J. M., & Doetsch, F. (2008) · Cell stem cell · doi:10.1016/j.stem.2008.07.025 · Cited by 1,033 · see citing works

Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions

Shen, Q., Wang, Y., Kokovay, E., Lin, G., Chuang, S.-M., Goderie, S. K., Roysam, B., & Temple, S. (2008) · Cell stem cell · doi:10.1016/j.stem.2008.07.026 · Cited by 1,027 · see citing works

Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain.

Gage, F. H., Coates, P. W., Palmer, T. D., Kuhn, H. G., Fisher, L. J., Suhonen, J., Peterson, D. A., Suhr, S. T., & Ray, J. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.25.11879 · Cited by 1,020 · see citing works

Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain

Mirzadeh, Z., Merkle, F. T., Soriano-Navarro, M., Garcia-Verdugo, J. M., & Alvarez-Buylla, A. (2008) · Cell stem cell · doi:10.1016/j.stem.2008.07.004 · Cited by 1,015 · see citing works

Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: A major site of neurogenesis

Haubensak, W. E., Attardo, A., Denk, W. T., & Huttner, W. Β. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308600100 · Cited by 1,004 · see citing works

GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain

Garcia, A. D. R., Doan, N., Imura, T., Bush, T. G., & Sofroniew, M. V. (2004) · Nature Neuroscience · doi:10.1038/nn1340 · Cited by 990 · see citing works

Are New Neurons Formed in the Brains of Adult Mammals?

Altman, J. (1962) · Science · doi:10.1126/science.135.3509.1127 · Cited by 975 · see citing works

Origin of oligodendrocytes in the subventricular zone of the adult brain

Menn, B., Garcia-Verdugo, J. M., Yaschine, C., Gonzalez-Perez, O., Rowitch, D., & Alvarez-Buylla, A. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.1299-06.2006 · Cited by 972 · see citing works

Dopamine depletion impairs precursor cell proliferation in Parkinson disease

Höglinger, G. U., Rizk, P., Mp, M., Duyckaerts, C. J., Oertel, W. H., Caillé, I., & Hirsch, É. C. (2004) · Nature Neuroscience · doi:10.1038/nn1265 · Cited by 946 · see citing works

Molecular Identity of Human Outer Radial Glia during Cortical Development

Pollen, A. A., Nowakowski, T. J., Chen, J., Retallack, H., Sandoval-Espinosa, C., Nicholas, C. R., Shuga, J., Liu, S. J., Oldham, M. C., Diaz, A., et al. (2015) · Cell · doi:10.1016/j.cell.2015.09.004 · Cited by 908 · see citing works

Asymmetric Inheritance of Radial Glial Fibers by Cortical Neurons

Miyata, T., Kawaguchi, A., Okano, H., & Ogawa, M. (2001) · Neuron · doi:10.1016/s0896-6273(01)00420-2 · Cited by 892 · see citing works

Division-Coupled Astrocytic Differentiation and Age-Related Depletion of Neural Stem Cells in the Adult Hippocampus

Encinas, J. M., Michurina, T. V., Peunova, N. I., Park, J.-H., Tordo, J., Peterson, D. A., Fishell, G., Koulakov, A. A., & Enikolopov, G. (2011) · Cell stem cell · doi:10.1016/j.stem.2011.03.010 · Cited by 891 · see citing works

Corridors of migrating neurons in the human brain and their decline during infancy

Sanai, N., Nguyen, T., Ihrie, R. A., Mirzadeh, Z., Tsai, H.-H., Wong, M., Gupta, N., Berger, M. S., Huang, E., Garcia-Verdugo, J.-M., et al. (2011) · Nature · doi:10.1038/nature10487 · Cited by 849 · see citing works

Radial glia give rise to adult neural stem cells in the subventricular zone

Merkle, F. T., Tramontin, A. D., García‐Verdugo, J. M., & Álvarez-Buylla, A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407893101 · Cited by 849 · see citing works

Radial Glia Serve as Neuronal Progenitors in All Regions of the Central Nervous System

Anthony, T. E., Klein, C., Fishell, G., & Heintz, N. (2004) · Neuron · doi:10.1016/s0896-6273(04)00140-0 · Cited by 834 · see citing works

Mosaic Organization of Neural Stem Cells in the Adult Brain

Merkle, F. T., Mirzadeh, Z., & Álvarez-Buylla, A. (2007) · Science · doi:10.1126/science.1144914 · Cited by 821 · see citing works

In Vivo Fate Analysis Reveals the Multipotent and Self-Renewal Capacities of Sox2+ Neural Stem Cells in the Adult Hippocampus

Suh, H., Consiglio, A., Ray, J., Sawai, T., D’Amour, K. A., & Gage, F. H. (2007) · Cell stem cell · doi:10.1016/j.stem.2007.09.002 · Cited by 818 · see citing works

New Neurons Follow the Flow of Cerebrospinal Fluid in the Adult Brain

Sawamoto, K., Wichterle, H., González-Pérez, Ó., Cholfin, J. A., Yamada, M., Spassky, N., Murcia, N. S., García‐Verdugo, J. M., Marín, Ó., Rubenstein, J. L. R., et al. (2006) · Science · doi:10.1126/science.1119133 · Cited by 803 · see citing works

Adult Mammalian Neural Stem Cells and Neurogenesis: Five Decades Later

Bond, A. M., Ming, G.-L., & Song, H. (2015) · Cell Stem Cell · doi:10.1016/j.stem.2015.09.003 · Cited by 791 · see citing works

Single-Cell RNA-Seq with Waterfall Reveals Molecular Cascades underlying Adult Neurogenesis

Shin, J., Berg, D. A., Zhu, Y., Shin, J. Y., Song, J., Bonaguidi, M. A., Enikolopov, G., Nauen, D. W., Christian, K. M., Ming, G.-L., et al. (2015) · Cell Stem Cell · doi:10.1016/j.stem.2015.07.013 · Cited by 784 · see citing works

Single-Cell Transcriptomics Reveals a Population of Dormant Neural Stem Cells that Become Activated upon Brain Injury

Llorens-Bobadilla, E., Zhao, S., Baser, A., Saiz-Castro, G., Zwadlo, K., & Martin-Villalba, A. (2015) · Cell Stem Cell · doi:10.1016/j.stem.2015.07.002 · Cited by 778 · see citing works

Regulation of adult neurogenesis by excitatory input and NMDA receptor activation in the dentate gyrus

Cameron, H. A., McEwen, B., & Gould, E. A. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-06-04687.1995 · Cited by 743 · see citing works

Network of tangential pathways for neuronal migration in adult mammalian brain

Doetsch, F. K., & Álvarez-Buylla, A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.25.14895 · Cited by 735 · see citing works

Adult Ependymal Cells Are Postmitotic and Are Derived from Radial Glial Cells during Embryogenesis

Spassky, N., Merkle, F. T., Flames, N., Tramontin, A. D., García-Verdugo, J. M., & Alvarez-Buylla, A. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.1108-04.2005 · Cited by 717 · see citing works

Essential roles of Notch signaling in maintenance of neural stem cells in developing and adult brains

Imayoshi, I., Sakamoto, M., Yamaguchi, M., Mori, K., & Kageyama, R. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.4987-09.2010 · Cited by 716 · see citing works

Pregnancy-Stimulated Neurogenesis in the Adult Female Forebrain Mediated by Prolactin

Shingo, T., Gregg, C., Enwere, E. K., Fujikawa, H., Hassam, R., Geary, C. L., Cross, J. C., & Weiss, S. (2003) · Science · doi:10.1126/science.1076647 · Cited by 711 · see citing works

Stress and adult neurogenesis

Mirescu, C., & Gould, E. (2006) · Hippocampus · doi:10.1002/hipo.20155 · Cited by 701 · see citing works

Maturation and Death of Adult-Born Olfactory Bulb Granule Neurons: Role of Olfaction

Petreanu, L., & Álvarez-Buylla, A. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-14-06106.2002 · Cited by 680 · see citing works

LeX/ssea-1 Is Expressed by Adult Mouse CNS Stem Cells, Identifying Them as Nonependymal

Capela, A., & Temple, S. (2002) · Neuron · doi:10.1016/s0896-6273(02)00835-8 · Cited by 671 · see citing works

Pax6 Controls Radial Glia Differentiation in the Cerebral Cortex

Götz, M., Stoykova, A., & Gruß, P. (1998) · Neuron · doi:10.1016/s0896-6273(00)80621-2 · Cited by 665 · see citing works

Murine features of neurogenesis in the human hippocampus across the lifespan from 0 to 100 years

Knoth, R., Singec, I., Ditter, M., Pantazis, G., Capetian, P., Meyer, R. P., Horvat, V., Volk, B., & Kempermann, G. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008809 · Cited by 650 · see citing works

The cerebrospinal fluid provides a proliferative niche for neural progenitor cells

Lehtinen, M. K., Zappaterra, M. W., Chen, X., Yang, Y. J., Hill, A. D., Lun, M., Maynard, T., Gonzalez, D., Kim, S., Ye, P., et al. (2011) · Neuron · doi:10.1016/j.neuron.2011.01.023 · Cited by 648 · see citing works

Prospective identification and purification of quiescent adult neural stem cells from their in vivo niche

Codega, P., Silva-Vargas, V., Paul, A., Maldonado-Soto, A. R., DeLeo, A. M., Pastrana, E., & Doetsch, F. (2014) · Neuron · doi:10.1016/j.neuron.2014.02.039 · Cited by 634 · see citing works

Cell types, lineage, and architecture of the germinal zone in the adult dentate gyrus

Seri, B., García‐Verdugo, J. M., Collado-Morente, L., McEwen, B. S., & Álvarez-Buylla, A. (2004) · The Journal of Comparative Neurology · doi:10.1002/cne.20288 · Cited by 628 · see citing works

On the control of germ cell development in Caenorhabditis elegans

Kimble, J. E., & White, J. G. (1981) · Developmental Biology · doi:10.1016/0012-1606(81)90284-0 · Cited by 603 · see citing works

The Adult Ventricular–Subventricular Zone (V-SVZ) and Olfactory Bulb (OB) Neurogenesis

Lim, D. A., & Alvarez-Buylla, A. (2016) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a018820 · Cited by 571 · see citing works

Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelination

Nait‐Oumesmar, B., Decker, L., Lachapelle, F., Avellana‐Adalid, V., Bachelin, C., & Van Evercooren, A. B. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00873.x · Cited by 560 · see citing works

Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats

Brezun, J. M., & Daszuta, A. (1999) · Neuroscience · doi:10.1016/s0306-4522(98)00693-9 · Cited by 549 · see citing works

Aging Results in Reduced Epidermal Growth Factor Receptor Signaling, Diminished Olfactory Neurogenesis, and Deficits in Fine Olfactory Discrimination

Enwere, E. K., Shingo, T., Gregg, C., Fujikawa, H., Ohta, S., & Weiss, S. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.2751-04.2004 · Cited by 549 · see citing works

De novo generation of neuronal cells from the adult mouse brain.

Richards, L. J., Kilpatrick, T. J., & Bartlett, P. F. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.18.8591 · Cited by 544 · see citing works

Adult Mammalian Forebrain Ependymal and Subependymal Cells Demonstrate Proliferative Potential, but only Subependymal Cells Have Neural Stem Cell Characteristics

Chiasson, B. J., Tropepe, V., Morshead, C. M., & van der Kooy, D. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-11-04462.1999 · Cited by 528 · see citing works

Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging

Leeman, D. S., Hebestreit, K., Ruetz, T., Webb, A. E., McKay, A., Pollina, E. A., Dulken, B. W., Zhao, X., Yeo, R. W., Ho, T. T., et al. (2018) · Science · doi:10.1126/science.aag3048 · Cited by 528 · see citing works

Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision

Song, J., Zhong, C., Bonaguidi, M. A., Sun, G. J., Hsu, D., Gu, Y., Meletis, K., Huang, Z. J., Ge, S., Enikolopov, G., et al. (2012) · Nature · doi:10.1038/nature11306 · Cited by 515 · see citing works

3H-thymidine-radiographic studies of neurogenesis in the rat olfactory bulb

Bayer, S. A. (1983) · Experimental Brain Research · doi:10.1007/bf00239197 · Cited by 503 · see citing works

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

Knobloch, M., Braun, S., Zurkirchen, L., Schoultz, C., Zamboni, N., Araúzo-Bravo, M., Kovacs, W. J., Karalay, Ö., Suter, U., Machado, R. A. C., et al. (2012) · Nature · doi:10.1038/nature11689 · Cited by 503 · see citing works

Microglia Enhance Neurogenesis and Oligodendrogenesis in the Early Postnatal Subventricular Zone

Shigemoto‐Mogami, Y., Hoshikawa, K., Goldman, J. E., Sekino, Y., & Sato, K. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.1619-13.2014 · Cited by 499 · see citing works

Embryonic origin of postnatal neural stem cells

Fuentealba, L. C., Rompani, S. B., Parraguez, J. I., Obernier, K., Romero, R., Cepko, C. L., & Alvarez-Buylla, A. (2015) · Cell · doi:10.1016/j.cell.2015.05.041 · Cited by 488 · see citing works

Subpopulation of nestin-expressing progenitor cells in the adult murine hippocampus shows electrophysiological and morphological characteristics of astrocytes

Filippov, V., Kronenberg, G., Pivneva, T. A., Reuter, K., Steiner, B., Wang, L.-P., Yamaguchi, M., Kettenmann, H., & Kempermann, G. (2003) · Molecular and Cellular Neuroscience · doi:10.1016/s1044-7431(03)00060-5 · Cited by 483 · see citing works

Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal

Aguirre, A. A., Rubio, M. E., & Gallo, V. (2010) · Nature · doi:10.1038/nature09347 · Cited by 482 · see citing works

Neurons Generated in the Adult Brain Are Recruited into Functional Circuits

Paton, J. A., & Nottebohm, F. (1984) · Science · doi:10.1126/science.6474166 · Cited by 466 · see citing works

Nonsynaptic GABA signaling in postnatal subventricular zone controls proliferation of GFAP-expressing progenitors

Liu, X., Wang, Q., Haydar, T. F., & Bordey, A. (2005) · Nature Neuroscience · doi:10.1038/nn1522 · Cited by 446 · see citing works

Extensive migration of young neurons into the infant human frontal lobe

Paredes, M. F., James, D., Gil-Perotin, S., Kim, H., Cotter, J. A., Ng, C., Sandoval, K., Rowitch, D. H., Xu, D., McQuillen, P. S., et al. (2016) · Science · doi:10.1126/science.aaf7073 · Cited by 391 · see citing works

Postnatal Development of Radial Glia and the Ventricular Zone (VZ): a Continuum of the Neural Stem Cell Compartment

Tramontin, A. D. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.6.580 · Cited by 386 · see citing works

Anatomy of the brain neurogenic zones revisited: Fractones and the fibroblast/macrophage network

Mercier, F., Kitasako, J. T., & Hatton, G. I. (2002) · The Journal of Comparative Neurology · doi:10.1002/cne.10342 · Cited by 384 · see citing works

GABA sets the tempo for activity-dependent adult neurogenesis

Ge, S., Pradhan, D. A., Ming, G., & Song, H. (2006) · Trends in Neurosciences · doi:10.1016/j.tins.2006.11.001 · Cited by 366 · see citing works

Adult SVZ Lineage Cells Home to and Leave the Vascular Niche via Differential Responses to SDF1/CXCR4 Signaling

Kokovay, E., Goderie, S. K., Wang, Y., Lotz, S., Lin, G., Sun, Y., Roysam, B., Shen, Q., & Temple, S. (2010) · Cell stem cell · doi:10.1016/j.stem.2010.05.019 · Cited by 358 · see citing works

Vasculature Guides Migrating Neuronal Precursors in the Adult Mammalian Forebrain via Brain-Derived Neurotrophic Factor Signaling

Snapyan, M., Lemasson, M., Brill, M. S., Blais, M., Massouh, M., Ninkovic, J., Gravel, C., Berthod, F., Götz, M., Barker, P. A., et al. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4956-08.2009 · Cited by 346 · see citing works

Subventricular Zone Stem Cells Are Heterogeneous with Respect to Their Embryonic Origins and Neurogenic Fates in the Adult Olfactory Bulb

Young, K. M., Fogarty, M., Kessaris, N., & Richardson, W. D. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0476-07.2007 · Cited by 343 · see citing works

Type‐2 cells as link between glial and neuronal lineage in adult hippocampal neurogenesis

Steiner, B., Klempin, F., Wang, L., Kott, M., Kettenmann, H., & Kempermann, G. (2006) · Glia · doi:10.1002/glia.20407 · Cited by 342 · see citing works

In Vivo Fate Mapping and Expression Analysis Reveals Molecular Hallmarks of Prospectively Isolated Adult Neural Stem Cells

Beckervordersandforth, R., Tripathi, P., Ninkovic, J., Bayam, E., Lepier, A., Stempfhuber, B., Kirchhoff, F., Hirrlinger, J., Haslinger, A., Lie, D. C., et al. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.11.017 · Cited by 335 · see citing works

Single-cell transcriptomic analysis defines heterogeneity and transcriptional dynamics in the adult neural stem cell lineage

Dulken, B. W., Leeman, D. S., Boutet, S. C., Hebestreit, K., & Brunet, A. (2017) · Cell Reports · doi:10.1016/j.celrep.2016.12.060 · Cited by 334 · see citing works

Proliferation “hot spots” in adult avian ventricular zone reveal radial cell division

Álvarez-Buylla, A., Theelen, M., & Nottebohm, F. (1990) · Neuron · doi:10.1016/0896-6273(90)90038-h · Cited by 331 · see citing works

Slowly dividing neural progenitors are an embryonic origin of adult neural stem cells

Furutachi, S., Miya, H., Watanabe, T., Kawai, H., Yamasaki, N., Harada, Y., Imayoshi, I., Nelson, M., Nakayama, K. I., Hirabayashi, Y., et al. (2015) · Nature Neuroscience · doi:10.1038/nn.3989 · Cited by 329 · see citing works

Pax6 Is Required for Making Specific Subpopulations of Granule and Periglomerular Neurons in the Olfactory Bulb

Kohwi, M., Osumi, N., Rubenstein, J. L. R., & Álvarez-Buylla, A. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1435-05.2005 · Cited by 329 · see citing works

Differential regulation of gliogenesis in the context of adult hippocampal neurogenesis in mice

Steiner, B., Kronenberg, G., Jessberger, S., Brandt, M., Reuter, K., & Kempermann, G. (2004) · Glia · doi:10.1002/glia.10337 · Cited by 326 · see citing works

Identification and characterization of neuroblasts in the subventricular zone and rostral migratory stream of the adult human brain

Wang, C., Liu, F., Liu, Y.-Y., Zhao, C.-H., You, Y., Wang, L., Zhang, J., Wei, B. K., Ma, T., Zhang, Q., et al. (2011) · Cell Research · doi:10.1038/cr.2011.83 · Cited by 309 · see citing works

Age-Dependent Niche Signals from the Choroid Plexus Regulate Adult Neural Stem Cells

Silva-Vargas, V., Maldonado-Soto, A. R., Mizrak, D., Codega, P., & Doetsch, F. (2016) · Cell stem cell · doi:10.1016/j.stem.2016.06.013 · Cited by 306 · see citing works

Live imaging of neurogenesis in the adult mouse hippocampus

Pilz, G.-A., Bottes, S., Betizeau, M., Jörg, D. J., Carta, S., April-Monn, S., Simons, B. D., Helmchen, F., & Jessberger, S. (2018) · Science · doi:10.1126/science.aao5056 · Cited by 306 · see citing works

Autoradiographic study of histogenesis in the mouse olfactory bulb. II. Cell proliferation and migration

Hinds, J. W. (1968) · The Journal of Comparative Neurology · doi:10.1002/cne.901340305 · Cited by 303 · see citing works

Novel Extracellular Matrix Structures in the Neural Stem Cell Niche Capture the Neurogenic Factor Fibroblast Growth Factor 2 from the Extracellular Milieu

Kerever, A., Schnack, J., Vellinga, D., Ichikawa, N., Moon, C., Arikawa‐Hirasawa, E., Efird, J. T., & Mercier, F. (2007) · Stem Cells · doi:10.1634/stemcells.2007-0082 · Cited by 287 · see citing works

The Distinct Temporal Origins of Olfactory Bulb Interneuron Subtypes

Batista‐Brito, R., Close, J., Machold, R. P., & Fishell, G. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.5625-07.2008 · Cited by 285 · see citing works

Hematopoietic stem cells count and remember self-renewal divisions

Bernitz, J. M., Kim, H. S., MacArthur, B., Sieburg, H., & Moore, K. (2016) · Cell · doi:10.1016/j.cell.2016.10.022 · Cited by 285 · see citing works

Direct cell–cell contact with the vascular niche maintains quiescent neural stem cells

Ottone, C., Krusche, B., Whitby, A., Clements, M., Quadrato, G., Pitulescu, M. E., Adams, R. H., & Parrinello, S. (2014) · Nature Cell Biology · doi:10.1038/ncb3045 · Cited by 279 · see citing works

Adult neural stem cells in distinct microdomains generate previously unknown interneuron types

Merkle, F. T., Fuentealba, L. C., Sanders, T. A., Magno, L., Kessaris, N., & Álvarez-Buylla, A. (2013) · Nature Neuroscience · doi:10.1038/nn.3610 · Cited by 277 · see citing works

A Subpopulation of Olfactory Bulb GABAergic Interneurons Is Derived from Emx1- and Dlx5/6-Expressing Progenitors

Kohwi, M., Petryniak, M. A., Long, J. E., Ekker, M., Obata, K., Yanagawa, Y., Rubenstein, J. L. R., & Álvarez-Buylla, A. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0254-07.2007 · Cited by 270 · see citing works

A subset of oligodendrocytes generated from radial glia in the dorsal spinal cord

Fogarty, M., Richardson, W., & Kessaris, N. (2005) · Development · doi:10.1242/dev.01777 · Cited by 270 · see citing works

Directed differentiation of hippocampal stem/progenitor cells in the adult brain

Jessberger, S., Toni, N., Clemenson, G. D., Ray, J., & Gage, F. H. (2008) · Nature Neuroscience · doi:10.1038/nn.2148 · Cited by 265 · see citing works

Human adult neurogenesis across the ages: An immunohistochemical study

Dennis, C. V., Suh, L. S., Rodriguez, M. L., Kril, J. J., & Sutherland, G. T. (2016) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12337 · Cited by 265 · see citing works

Cell cycle and lineage progression of neural progenitors in the ventricular-subventricular zones of adult mice

Ponti, G., Obernier, K., Guinto, C. D., Jose, L., Bonfanti, L., & Álvarez-Buylla, A. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1219563110 · Cited by 260 · see citing works

A Single-Cell RNA Sequencing Study Reveals Cellular and Molecular Dynamics of the Hippocampal Neurogenic Niche

Artegiani, B., Lyubimova, A., Muraro, M., van Es, J. H., van Oudenaarden, A., & Clevers, H. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.11.050 · Cited by 259 · see citing works

Dopaminergic nigrostriatal projections regulate neural precursor proliferation in the adult mouse subventricular zone

Baker, S. A., Baker, K. A., & Hagg, T. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03486.x · Cited by 258 · see citing works

Persistent Sonic Hedgehog Signaling in Adult Brain Determines Neural Stem Cell Positional Identity

Ihrie, R. A., Shah, J. K., Harwell, C. C., Levine, J. H., Guinto, C. D., Lezameta, M., Kriegstein, A. R., & Alvarez-Buylla, A. (2011) · Neuron · doi:10.1016/j.neuron.2011.05.018 · Cited by 255 · see citing works

Adult Neurogenesis Is Sustained by Symmetric Self-Renewal and Differentiation

Obernier, K., Cebrian-Silla, A., Thomson, M., Parraguez, J. I., Anderson, R., Guinto, C., Rodas Rodriguez, J., Garcia-Verdugo, J.-M., & Alvarez-Buylla, A. (2018) · Cell Stem Cell · doi:10.1016/j.stem.2018.01.003 · Cited by 250 · see citing works

Integrating new neurons into the adult olfactory bulb: joining the network, life–death decisions, and the effects of sensory experience

Lledo, P., & Saghatelyan, A. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.03.005 · Cited by 248 · see citing works

Radial organization of the hippocampal dentate gyrus: A Golgi, ultrastructural, and immunocytochemical analysis in the developing rhesus monkey

Eckenhoff, M. F., & RAKIC, P. T. (1984) · The Journal of Comparative Neurology · doi:10.1002/cne.902230102 · Cited by 239 · see citing works

Leukemia Inhibitory Factor Promotes Neural Stem Cell Self-Renewal in the Adult Brain

Bauer, Š., & Patterson, P. H. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3047-06.2006 · Cited by 234 · see citing works

Spatiotemporal coordination of stem cell commitment during epidermal homeostasis

Rompolas, P., Mesa, K. R., Kawaguchi, K., Park, S., Gonzalez, D. G., Brown, S., Boucher, J. D., Klein, A. M., & Greco, V. (2016) · Science · doi:10.1126/science.aaf7012 · Cited by 228 · see citing works

Blood Vessels Form a Scaffold for Neuroblast Migration in the Adult Olfactory Bulb

Bovetti, S., Hsieh, Y.-C., Bovolin, P., Perroteau, I., Toida, K., & Puché, A. C. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0678-07.2007 · Cited by 227 · see citing works

GFAP-positive progenitor cells produce neurons and oligodendrocytes throughout the CNS

Casper, K. B., & McCarthy, K. D. (2006) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2005.12.006 · Cited by 227 · see citing works

The Timing for Neuronal Maturation in the Adult Hippocampus Is Modulated by Local Network Activity

Piatti, V. C., Davies-Sala, M. G., Esposito, M. S., Mongiat, L. A., Trinchero, M. F., & Schinder, A. F. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.1380-11.2011 · Cited by 226 · see citing works

A distinct population of microglia supports adult neurogenesis in the subventricular zone

Ribeiro Xavier, A. L., Kress, B. T., Goldman, S. A., Lacerda de Menezes, J. R., & Nedergaard, M. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.1217-15.2015 · Cited by 225 · see citing works

Neurotransmitter-mediated control of neurogenesis in the adult vertebrate brain

Berg, D. A., Belnoue, L., Song, H., & Simon, A. (2013) · Development · doi:10.1242/dev.088005 · Cited by 224 · see citing works

Parvalbumin interneurons mediate neuronal circuitry-neurogenesis coupling in the adult hippocampus

Song, J., Sun, J., Moss, J., Wen, Z., Sun, G. J., Hsu, D., Zhong, C., Davoudi, H., Christian, K. M., Toni, N., et al. (2013) · Nature Neuroscience · doi:10.1038/nn.3572 · Cited by 223 · see citing works

Single-Cell Transcriptomics and Fate Mapping of Ependymal Cells Reveals an Absence of Neural Stem Cell Function

Shah, P. T., Stratton, J. A., Stykel, M. G., Abbasi, S., Sharma, S., Mayr, K. A., Koblinger, K., Whelan, P. J., & Biernaskie, J. (2018) · Cell · doi:10.1016/j.cell.2018.03.063 · Cited by 221 · see citing works

Vascular niche factor PEDF modulates Notch-dependent stemness in the adult subependymal zone

Andreu-Agulló, C., Morante‐Redolat, J. M., Delgado, A. C., & Fariñas, I. (2009) · Nature Neuroscience · doi:10.1038/nn.2437 · Cited by 218 · see citing works

Neural progenitor cells regulate microglia functions and activity

Mosher, K. I., Andres, R. H., Fukuhara, T., Bieri, G., Hasegawa‐Moriyama, M., He, Y., Guzman, R. G., & Wyss‐Coray, T. (2012) · Nature Neuroscience · doi:10.1038/nn.3233 · Cited by 218 · see citing works

Dopamine Specifically Inhibits Forebrain Neural Stem Cell Proliferation, Suggesting a Novel Effect of Antipsychotic Drugs

Kippin, T. E. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1120-05.2005 · Cited by 214 · see citing works

A Transcriptional Mechanism Integrating Inputs from Extracellular Signals to Activate Hippocampal Stem Cells

Andersen, J., Urbán, N., Achimastou, A., Ito, A., Simic, M., Ullom, K., Martynoga, B., Lebel, M., Göritz, C., Frisén, J., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.08.004 · Cited by 212 · see citing works

VCAM1 Is Essential to Maintain the Structure of the SVZ Niche and Acts as an Environmental Sensor to Regulate SVZ Lineage Progression

Kokovay, E., Wang, Y., Kusek, G., Wurster, R., Lederman, P. L., Lowry, N. A., Shen, Q., & Temple, S. (2012) · Cell stem cell · doi:10.1016/j.stem.2012.06.016 · Cited by 199 · see citing works

A mosaic world: puzzles revealed by adult neural stem cell heterogeneity

Chaker, Z., Codega, P., & Doetsch, F. (2016) · WIREs Developmental Biology · doi:10.1002/wdev.248 · Cited by 198 · see citing works

Developmental Emergence of Adult Neural Stem Cells as Revealed by Single-Cell Transcriptional Profiling

Yuzwa, S. A., Borrett, M. J., Innes, B. T., Voronova, A., Ketela, T., Kaplan, D. R., Bader, G. D., & Miller, F. D. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.12.017 · Cited by 195 · see citing works

Depletion of norepinephrine decreases the proliferation, but does not influence the survival and differentiation, of granule cell progenitors in the adult rat hippocampus

Kulkarni, V. A., Jha, S., & Vaidya, V. A. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02268.x · Cited by 192 · see citing works

Fast clonal expansion and limited neural stem cell self-renewal in the adult subependymal zone

Calzolari, F., Michel, J., Baumgart, E. V., Theis, F. J., Götz, M., & Ninkovic, J. (2015) · Nature Neuroscience · doi:10.1038/nn.3963 · Cited by 186 · see citing works

Troy+ brain stem cells cycle through quiescence and regulate their number by sensing niche occupancy

Basak, O., Krieger, T. G., Muraro, M. J., Wiebrands, K., Stange, D. E., Frias-Aldeguer, J., Rivron, N. C., van de Wetering, M., van Es, J. H., van Oudenaarden, A., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1715911114 · Cited by 186 · see citing works

The cerebrospinal fluid: regulator of neurogenesis, behavior, and beyond

Zappaterra, M., & Lehtinen, M. K. (2012) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-012-0957-x · Cited by 182 · see citing works

Neurogenic Subventricular Zone Stem/Progenitor Cells Are Notch1-Dependent in Their Active But Not Quiescent State

Başak, O., Giachino, C., Fiorini, E., MacDonald, H. R., & Taylor, V. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0455-12.2012 · Cited by 175 · see citing works

Norepinephrine Directly Activates Adult Hippocampal Precursors via β3-Adrenergic Receptors

Jhaveri, D. J., Mackay, E., Hamlin, A. S., Marathe, S. V., Nandam, L. S., Vaidya, V. A., & Bartlett, P. F. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3780-09.2010 · Cited by 174 · see citing works

Hippocampal Radial Glial Subtypes and Their Neurogenic Potential in Human Fetuses and Healthy and Alzheimer’s Disease Adults

Cipriani, S., Ferrer, I., Aronica, E., Kovacs, G. G., Verney, C., Nardelli, J., Khung, S., Delezoide, A.-L., Milenkovic, I., Rasika, S., et al. (2018) · Cerebral Cortex · doi:10.1093/cercor/bhy096 · Cited by 169 · cited 1× · see citing works

Generation of Distinct Types of Periglomerular Olfactory Bulb Interneurons during Development and in Adult Mice: Implication for Intrinsic Properties of the Subventricular Zone Progenitor Population

Marchis, S. D., Bovetti, S., Carletti, B., Hsieh, Y.-C., Garzotto, D., Peretto, P., Fasolo, A., Puché, A. C., & Rossi, F. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.2870-06.2007 · Cited by 167 · see citing works

Spatial and temporal expression of short, long/medium, or both opsins in human fetal cones

Xiao, M., & Hendrickson, A. E. (2000) · The Journal of Comparative Neurology · doi:10.1002/1096-9861(20001002)425:4 · Cited by 165 · see citing works

Dorsal Radial Glia Generate Olfactory Bulb Interneurons in the Postnatal Murine Brain

Ventura, R. E., & Goldman, J. E. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0399-07.2007 · Cited by 161 · see citing works

Axonal Control of the Adult Neural Stem Cell Niche

Tong, C. K., Chen, J., Cebrián‐Silla, A., Mirzadeh, Z., Obernier, K., Guinto, C. D., Tecott, L. H., García‐Verdugo, J. M., Kriegstein, A. R., & Álvarez-Buylla, A. (2014) · Cell stem cell · doi:10.1016/j.stem.2014.01.014 · Cited by 150 · see citing works

miR-7a regulation of Pax6 controls spatial origin of forebrain dopaminergic neurons

de Chevigny, A., Coré, N., Follert, P., Gaudin, M., Barbry, P., Béclin, C., & Cremer, H. (2012) · Nature Neuroscience · doi:10.1038/nn.3142 · Cited by 145 · see citing works

Primary cilia are required in a unique subpopulation of neural progenitors

Tong, C. K., Han, Y.-G., Shah, J. K., Obernier, K., Guinto, C. D., & Álvarez-Buylla, A. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1321425111 · Cited by 143 · see citing works

Ultrastructural characterization of synaptic terminals formed on newly generated neurons in a song control nucleus of the adult canary forebrain

Burd, G. D., & Nottebohm, F. (1985) · The Journal of Comparative Neurology · doi:10.1002/cne.902400204 · Cited by 142 · see citing works

Brain size and limits to adult neurogenesis

Paredes, M. F., Sorrells, S. F., García‐Verdugo, J. M., & Álvarez-Buylla, A. (2015) · The Journal of Comparative Neurology · doi:10.1002/cne.23896 · Cited by 142 · see citing works

Identification of distinct ChAT+ neurons and activity-dependent control of postnatal SVZ neurogenesis

Paez-Gonzalez, P., Asrican, B., Rodriguez, E., & Kuo, C. T. (2014) · Nature Neuroscience · doi:10.1038/nn.3734 · Cited by 140 · see citing works

Dll1 maintains quiescence of adult neural stem cells and segregates asymmetrically during mitosis

Kawaguchi, D., Furutachi, S., Kawai, H., Hozumi, K., & Gotoh, Y. (2013) · Nature Communications · doi:10.1038/ncomms2895 · Cited by 140 · see citing works

Cell cycle restriction by histone H2AX limits proliferation of adult neural stem cells

Fernando, R. N., Eleuteri, B., Abdelhady, S., Nussenzweig, A., Andäng, M., & Ernfors, P. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1014993108 · Cited by 138 · see citing works

Betacellulin promotes cell proliferation in the neural stem cell niche and stimulates neurogenesis

Gómez‐Gaviro, M. V., Scott, C. E., Sesay, A. K., Matheu, A., Booth, S., Galichet, C., & Lovell-Badge, R. H. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1016199109 · Cited by 137 · see citing works

Hypothalamic regulation of regionally distinct adult neural stem cells and neurogenesis

Paul, A., Chaker, Z., & Doetsch, F. (2017) · Science · doi:10.1126/science.aal3839 · Cited by 137 · cited 1× · see citing works

Symmetric vs. Asymmetric Stem Cell Divisions: An Adaptation against Cancer?

Shahriyari, L., & Komarova, N. L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076195 · Cited by 136 · see citing works

Tangential migration of neuronal precursors of glutamatergic neurons in the adult mammalian brain

Sun, G. J., Zhou, Y. F., Stadel, R. P., Moss, J., Yong, J. H. A., Ito, S., Kawasaki, N. K., Phan, A. T., Oh, J. H., Modak, N., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1508545112 · Cited by 134 · see citing works

Heterogeneity of Radial Glia-Like Cells in the Adult Hippocampus

Gebara, E., Bonaguidi, M. A., Beckervordersandforth, R., Sultan, S., Udry, F., Gijs, P.-J., Lie, D. C., Ming, G., Song, H., & Toni, N. (2016) · Stem Cells · doi:10.1002/stem.2266 · Cited by 133 · see citing works

Neuronal Circuitry Mechanisms Regulating Adult Mammalian Neurogenesis

Song, J., Olsen, R. H. J., Sun, J., Ming, G.-L., & Song, H. (2016) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a018937 · Cited by 125 · see citing works

Fine processes of Nestin-GFP–positive radial glia-like stem cells in the adult dentate gyrus ensheathe local synapses and vasculature

Moss, J., Gebara, E., Bushong, E. A., Sánchez-Pascual, I., O’Laoi, R., M’Ghari, I. E., Kocher-Braissant, J., Ellisman, M. H., & Toni, N. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1514652113 · Cited by 120 · see citing works

Diazepam Binding Inhibitor Promotes Progenitor Proliferation in the Postnatal SVZ by Reducing GABA Signaling

Alfonso, J., Magueresse, C. L., Zuccotti, A., Khodosevich, K. V., & Monyer, H. (2012) · Cell stem cell · doi:10.1016/j.stem.2011.11.011 · Cited by 117 · see citing works

Unsupervised Learning and Adaptation in a Model of Adult Neurogenesis

Cecchi, G., Petreanu, L., Álvarez-Buylla, A., & Magnasco, M. O. (2001) · Journal of Computational Neuroscience · doi:10.1023/a:1012849801892 · Cited by 114 · see citing works

Age-related changes in astrocytic and ependymal cells of the subventricular zone

Capilla‐González, V., Cebrián‐Silla, A., Guerrero‐Cazares, H., García‐Verdugo, J. M., & Quiñones‐Hinojosa, A. (2014) · Glia · doi:10.1002/glia.22642 · Cited by 108 · see citing works

Differential activation of microglia in neurogenic versus non‐neurogenic regions of the forebrain

Goings, G. E., Kozlowski, D. A., & Szele, F. G. (2006) · Glia · doi:10.1002/glia.20381 · Cited by 107 · see citing works

Homeostatic neurogenesis in the adult hippocampus does not involve amplification of Ascl1high intermediate progenitors

Lugert, S., Vogt, M. A., Tchorz, J. S., Müller, M. M., Giachino, C., & Taylor, V. (2012) · Nature Communications · doi:10.1038/ncomms1670 · Cited by 106 · see citing works

Epithelial Sodium Channel Regulates Adult Neural Stem Cell Proliferation in a Flow-Dependent Manner

Petrik, D., Myoga, M. H., Grade, S., Gerkau, N. J., Pusch, M., Rose, C. R., Grothe, B., & Götz, M. (2018) · Cell Stem Cell · doi:10.1016/j.stem.2018.04.016 · Cited by 104 · see citing works

Distinct Mammalian Precursors Are Committed to Generate Neurons with Defined Dendritic Projection Patterns

Kelsch, W., Mosley, C., Lin, C.-W., & Lois, C. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050300 · Cited by 100 · see citing works

A Dorsal SHH-Dependent Domain in the V-SVZ Produces Large Numbers of Oligodendroglial Lineage Cells in the Postnatal Brain

Tong, C. K., Fuentealba, L. C., Shah, J. K., Lindquist, R. A., Ihrie, R. A., Guinto, C. D., Rodas-Rodriguez, J. L., & Álvarez-Buylla, A. (2015) · Stem Cell Reports · doi:10.1016/j.stemcr.2015.08.013 · Cited by 99 · see citing works

Traumatic Brain Injury Activation of the Adult Subventricular Zone Neurogenic Niche

Chang, E. H., Adorján, I., Mundim, M. V., Sun, B., Dizon, M. L. V., & Szele, F. G. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2016.00332 · Cited by 92 · see citing works

Radial glial cells in the adult dentate gyrus: what are they and where do they come from?

Berg, D. A., Bond, A. M., Ming, G.-L., & Song, H. (2018) · F1000Research · doi:10.12688/f1000research.12684.1 · Cited by 89 · see citing works

Diazepam Binding Inhibitor Promotes Stem Cell Expansion Controlling Environment-Dependent Neurogenesis

Dumitru, I., Neitz, A., Alfonso, J., & Monyer, H. (2017) · Neuron · doi:10.1016/j.neuron.2017.03.003 · Cited by 88 · see citing works

Adult-born neurons facilitate olfactory bulb pattern separation during task engagement

Li, W. L., Chu, M. W., Wu, A., Suzuki, Y., Imayoshi, I., & Komiyama, T. (2018) · eLife · doi:10.7554/elife.33006 · Cited by 88 · see citing works

Gap junction‐mediated calcium waves define communication networks among murine postnatal neural progenitor cells

Lacar, B., Young, S. Z., Platel, J., & Bordey, A. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07901.x · Cited by 86 · see citing works

Area-specific regulation of quiescent neural stem cells by Notch3 in the adult mouse subependymal zone

Kawai, H., Kawaguchi, D., Kuebrich, B. D., Kitamoto, T., Yamaguchi, M., Gotoh, Y., & Furutachi, S. (2017) · The Journal of Neuroscience · doi:10.1523/jneurosci.0001-17.2017 · Cited by 85 · cited 2× · see citing works

NKCC1 Knockdown Decreases Neuron Production through GABAA-Regulated Neural Progenitor Proliferation and Delays Dendrite Development

Young, S. Z., Taylor, M. M., Wu, S. L. Y., Ikeda‐Matsuo, Y., Kubera, C., & Bordey, A. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.2864-12.2012 · Cited by 74 · see citing works

Optogenetic stimulation of glutamatergic neuronal activity in the striatum enhances neurogenesis in the subventricular zone of normal and stroke mice

Song, M., Yu, S. P., Mohamad, O., Cao, W., Wei, Z. Z., Gu, X., Jiang, M. Q., & Wei, L. (2016) · Neurobiology of Disease · doi:10.1016/j.nbd.2016.11.005 · Cited by 72 · see citing works

Adult-born neurons boost odor-reward association

Grelat, A., Benoit, L., Wagner, S., Moigneu, C., Lledo, P.-M., & Alonso, M. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1716400115 · Cited by 72 · see citing works

Persistent Expression of VCAM1 in Radial Glial Cells Is Required for the Embryonic Origin of Postnatal Neural Stem Cells

Hu, X.-L., Chen, G., Zhang, S., Zheng, J., Wu, J., Bai, Q., Wang, Y., Li, J., Wang, H., Han, F., et al. (2017) · Neuron · doi:10.1016/j.neuron.2017.06.047 · Cited by 66 · see citing works

Hopx distinguishes hippocampal from lateral ventricle neural stem cells

Li, D., Takeda, N., Jain, R., Manderfield, L. J., Liu, F., Li, L., Anderson, S. A., & Epstein, J. A. (2015) · Stem Cell Research · doi:10.1016/j.scr.2015.09.015 · Cited by 62 · see citing works

Fractone‐heparan sulphates mediate FGF‐2 stimulation of cell proliferation in the adult subventricular zone

Douet, V., Kerever, A., Arikawa‐Hirasawa, E., & Mercier, F. (2013) · Cell Proliferation · doi:10.1111/cpr.12023 · Cited by 62 · see citing works

Fractone Bulbs Derive from Ependymal Cells and Their Laminin Composition Influence the Stem Cell Niche in the Subventricular Zone

Nascimento, M. A., Sorokin, L. M., & Coelho‐Sampaio, T. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.3064-17.2018 · Cited by 61 · see citing works

Endogenous neurogenic cell response in the mature mammalian brain following traumatic injury

Sun, D. (2015) · Experimental Neurology · doi:10.1016/j.expneurol.2015.04.017 · Cited by 60 · see citing works

Embryonic and postnatal neurogenesis produce functionally distinct subclasses of dopaminergic neuron

Galliano, E., Franzoni, E., Breton, M., Chand, A. N., Byrne, D. J., Murthy, V. N., & Grubb, M. S. (2018) · eLife · doi:10.7554/elife.32373 · Cited by 54 · see citing works

Agonist-induced restoration of hippocampal neurogenesis and cognitive improvement in a model of cholinergic denervation

Kampen, J. M. V., & Eckman, C. B. (2009) · Neuropharmacology · doi:10.1016/j.neuropharm.2009.12.005 · Cited by 53 · see citing works

Midbrain Dopamine Neurons Associated with Reward Processing Innervate the Neurogenic Subventricular Zone

Lennington, J. B., Pope, S., Goodheart, A. E., Drozdowicz, L. B., Daniels, S. B., Salamone, J. D., & Conover, J. C. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.1197-11.2011 · Cited by 50 · see citing works

Bone morphogenetic protein-4 inhibits adult neurogenesis and is regulated by fractone-associated heparan sulfates in the subventricular zone

Mercier, F., & Douet, V. (2014) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2014.03.005 · Cited by 48 · see citing works

Opposing Effects of α2- and β-Adrenergic Receptor Stimulation on Quiescent Neural Precursor Cell Activity and Adult Hippocampal Neurogenesis

Jhaveri, D. J., Nanavaty, I. N., Prosper, B. W., Marathe, S. V., Husain, B. F. A., Kernie, S. G., Bartlett, P. F., & Vaidya, V. A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098736 · Cited by 47 · see citing works

A Temporal Transcriptional Switch Governs Stem Cell Division, Neuronal Numbers, and Maintenance of Differentiation

Mora, N., Oliva, C., Fiers, M. W. E. J., Ejsmont, R. K., Soldano, A., Zhang, T., Yan, J., Claeys, A., Geest, N. D., & Hassan, B. A. (2018) · Developmental Cell · doi:10.1016/j.devcel.2018.02.023 · Cited by 45 · see citing works

Epigenetic regulation of neural stem cell property from embryo to adult

Murao, N., Noguchi, H., & Nakashima, K. (2016) · Neuroepigenetics · doi:10.1016/j.nepig.2016.01.001 · Cited by 43 · see citing works

Fractone-heparan sulfates mediate BMP-7 inhibition of cell proliferation in the adult subventricular zone

Douet, V., Arikawa‐Hirasawa, E., & Mercier, F. (2012) · Neuroscience Letters · doi:10.1016/j.neulet.2012.08.077 · Cited by 41 · see citing works

Unique Organization of the Nuclear Envelope in the Post-natal Quiescent Neural Stem Cells

Cebrián‐Silla, A., Alfaro‐Cervelló, C., Herranz‐Pérez, V., Kaneko, N., Park, D. H., Sawamoto, K., Álvarez-Buylla, A., Lim, D. A., & García‐Verdugo, J. M. (2017) · Stem Cell Reports · doi:10.1016/j.stemcr.2017.05.024 · Cited by 41 · see citing works

Embryonic Nkx2.1-expressing neural precursor cells contribute to the regional heterogeneity of adult V–SVZ neural stem cells

Delgado, R. N., & Lim, D. A. (2015) · Developmental Biology · doi:10.1016/j.ydbio.2015.09.008 · Cited by 40 · see citing works

GABAergic striatal neurons project dendrites and axons into the postnatal subventricular zone leading to calcium activity

Young, S. Z., Lafourcade, C., Platel, J., Lin, T. V., & Bordey, A. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00010 · Cited by 40 · see citing works

Proliferation and cilia dynamics in neural stem cells prospectively isolated from the SEZ

Khatri, P., Obernier, K., Simeonova, I. K., Hellwig, A., Hölzl‐Wenig, G., Mandl, C., Scholl, C., Wölfl, S., Winkler, J., Gaspar, J. A., et al. (2014) · Scientific Reports · doi:10.1038/srep03803 · Cited by 39 · see citing works

HDL-like lipoproteins in cerebrospinal fluid affect neural cell activity through lipoprotein-associated sphingosine 1-phosphate

Sato, K., Malchinkhuu, E., Horiuchi, Y., Mogi, C., Tomura, H., Tosaka, M., Yoshimoto, Y., Kuwabara, A., & Okajima, F. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.05.131 · Cited by 34 · see citing works

Strategies targeting endogenous neurogenic cell response to improve recovery following traumatic brain injury

Patel, K., & Sun, D. (2016) · Brain Research · doi:10.1016/j.brainres.2016.01.055 · Cited by 34 · see citing works

Developmental forebrain cholinergic lesion and environmental enrichment: Behaviour, CA1 cytoarchitecture and neurogenesis

Fréchette, M., Rennie, K., & Pappas, B. A. (2008) · Brain Research · doi:10.1016/j.brainres.2008.11.082 · Cited by 33 · see citing works

Stem cell population asymmetry can reduce rate of replicative aging

Hormoz, S. (2013) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2013.04.018 · Cited by 13 · see citing works

Intrinsic regulation of adult subventricular zone neural progenitor cells and the effect of brain injury.

Jones, K. S., & Connor, B. J. (2012) · Europe PMC (PubMed Central) · Cited by 8 · see citing works

Evaluation of prostaglandin D2 as a CSF leak marker: implications in safe epidural anesthesia

Pentyala, Kondabolu, S., Adsumelli, R. S. N., Schabel, J., & Glass, P. S. A. (2011) · Local and Regional Anesthesia · doi:10.2147/lra.s18053 · Cited by 6 · see citing works

USP9X deletion elevates the density of oligodendrocytes within the postnatal dentate gyrus

Oishi, S., Zalucki, O. H., Premarathne, S., Wood, S., & Piper, M. (2016) · Neurogenesis · doi:10.1080/23262133.2016.1235524 · Cited by 6 · see citing works

A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain

Yao, Z., van Velthoven, C. T. J., Kunst, M., Zhang, M., McMillen, D., Lee, C., Jung, W., Goldy, J., Abdelhak, A., Aitken, M., et al. (2023) · Nature · doi:10.1038/s41586-023-06812-z · Cited by 1,194 · see citing works

Molecularly defined and spatially resolved cell atlas of the whole mouse brain

Zhang, M., Pan, X., Jung, W., Halpern, A. R., Eichhorn, S. W., Lei, Z., Cohen, L., Smith, K. A., Tasic, B., Yao, Z., et al. (2023) · Nature · doi:10.1038/s41586-023-06808-9 · Cited by 506 · see citing works

Quiescence of Adult Mammalian Neural Stem Cells: A Highly Regulated Rest

Urbán, N., Blomfield, I. M., & Guillemot, F. (2019) · Neuron · doi:10.1016/j.neuron.2019.09.026 · Cited by 370 · see citing works

Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis

Wu, A., & Zhang, J. (2023) · Journal of Neuroinflammation · doi:10.1186/s12974-023-02964-x · Cited by 327 · see citing works

Formation and integration of new neurons in the adult hippocampus

Denoth‐Lippuner, A., & Jessberger, S. (2021) · Nature reviews. Neuroscience · doi:10.1038/s41583-021-00433-z · Cited by 274 · see citing works

Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex

Uzquiano, A., Kedaigle, A. J., Pigoni, M., Paulsen, B. D. S., Adiconis, X., Kim, K., Faits, T., Nagaraja, S., Antón-Bolaños, N., Gerhardinger, C., et al. (2022) · Cell · doi:10.1016/j.cell.2022.09.010 · Cited by 250 · see citing works

Aging and Rejuvenation of Neural Stem Cells and Their Niches

Navarro Negredo, P., Yeo, R. W., & Brunet, A. (2020) · Cell Stem Cell · doi:10.1016/j.stem.2020.07.002 · Cited by 246 · see citing works

Deep learning-based predictive identification of neural stem cell differentiation

Zhu, Y., Huang, R., Wu, Z., Song, S., Cheng, L., & Zhu, R. (2021) · Nature Communications · doi:10.1038/s41467-021-22758-0 · Cited by 231 · see citing works

Cellular transcriptomics reveals evolutionary identities of songbird vocal circuits

Colquitt, B. M., Merullo, D. P., Konopka, G., Roberts, T. F., & Brainard, M. S. (2021) · Science · doi:10.1126/science.abd9704 · Cited by 169 · see citing works

SOX Transcription Factors as Important Regulators of Neuronal and Glial Differentiation During Nervous System Development and Adult Neurogenesis

Stevanović, M. J., Drakulić, D., Lazic, A., Ninković, D. S., Schwirtlich, M., & Mojsin, M. M. (2021) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2021.654031 · Cited by 158 · see citing works

Early stem cell aging in the mature brain

Ibrayeva, A., Bay, M., Pu, E., Jörg, D. J., Peng, L., Jun, H., Zhang, N., Aaron, D., Lin, C., Resler, G., et al. (2021) · Cell Stem Cell · doi:10.1016/j.stem.2021.03.018 · Cited by 137 · see citing works

Semaphorins in Adult Nervous System Plasticity and Disease

Carulli, D., de Winter, F., & Verhaagen, J. (2021) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2021.672891 · Cited by 137 · see citing works

Targeting Cardiac Stem Cell Senescence to Treat Cardiac Aging and Disease

Cianflone, E., Torella, M., Biamonte, F., Angelis, A. D., Urbanek, K., Costanzo, F. S., Rota, M., Ellison, G. M., & Torella, D. (2020) · Cells · doi:10.3390/cells9061558 · Cited by 134 · see citing works

Experimental models and tools to tackle glioblastoma

Robertson, F., Marqués‐Torrejón, M. Á., Morrison, G. M., & Pollard, S. M. (2019) · Disease Models & Mechanisms · doi:10.1242/dmm.040386 · Cited by 121 · see citing works

3D and organoid culture in research: physiology, hereditary genetic diseases and cancer

Suarez-Martinez, E., Suazo-Sanchez, I., Celis-Romero, M., & Carnero, A. (2022) · Cell & Bioscience · doi:10.1186/s13578-022-00775-w · Cited by 118 · see citing works

Communication, Cross Talk, and Signal Integration in the Adult Hippocampal Neurogenic Niche

Vicidomini, C., Guo, N., & Sahay, A. (2020) · Neuron · doi:10.1016/j.neuron.2019.11.029 · Cited by 107 · see citing works

Extracellular Vesicles as an Emerging Frontier in Spinal Cord Injury Pathobiology and Therapy

Dutta, D., Khan, N., Wu, J., & Jay, S. M. (2021) · Trends in Neurosciences · doi:10.1016/j.tins.2021.01.003 · Cited by 112 · see citing works

Carbon Nanotube–Hydrogel Composites Facilitate Neuronal Differentiation While Maintaining Homeostasis of Network Activity

Ye, L., Ji, H., Liu, J., Tu, C., Kappl, M., Koynov, K., Vogt, J., & Butt, H. (2021) · Advanced Materials · doi:10.1002/adma.202102981 · Cited by 111 · see citing works

Mitochondrial function in spinal cord injury and regeneration

Slater, P. G., Domínguez-Romero, M. E., Villarreal, M., Eisner, V., & Larraı́n, J. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04261-x · Cited by 110 · see citing works

Neural stem cell-derived exosomes and regeneration: cell-free therapeutic strategies for traumatic brain injury

Zhong, L., Wang, J., Wang, P., Liu, X., Liu, P., Cheng, X., Cao, L., Wu, H., Chen, J., & Zhou, L. (2023) · Stem Cell Research & Therapy · doi:10.1186/s13287-023-03409-1 · Cited by 110 · see citing works

Surface Topography and Electrical Signaling: Single and Synergistic Effects on Neural Differentiation of Stem Cells

Eftekhari, B. S., Eskandari, M., Janmey, P. A., Samadikuchaksaraei, A., & Gholipourmalekabadi, M. (2020) · Advanced Functional Materials · doi:10.1002/adfm.201907792 · Cited by 102 · see citing works

Therapeutic Plasticity of Neural Stem Cells

Ottoboni, L., von Wunster, B., & Martino, G. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.00148 · Cited by 98 · see citing works

The Use of Stem Cell-Derived Organoids in Disease Modeling: An Update

Azar, J. H., Bahmad, H. F., Daher, D., Moubarak, M. M., Hadadeh, O., Monzer, A., Bitar, S. A., Jamal, M., Al‐Sayegh, M., & Abou-Kheir, W. G. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22147667 · Cited by 101 · see citing works

Adult neural stem cell activation in mice is regulated by the day/night cycle and intracellular calcium dynamics

Gengatharan, A., Malvaut, S., Marymonchyk, A., Ghareghani, M., Snapyan, M., Fischer-Sternjak, J., Ninkovic, J., Götz, M., & Saghatelyan, A. (2021) · Cell · doi:10.1016/j.cell.2020.12.026 · Cited by 97 · see citing works

Structure and Function of the Blood–Brain Barrier (BBB)

Benz, F., & Liebner, S. (2020) · Handbook of experimental pharmacology · doi:10.1007/164_2020_404 · Cited by 97 · see citing works

Cortical Neural Stem Cell Lineage Progression Is Regulated by Extrinsic Signaling Molecule Sonic Hedgehog

Zhang, Y., Liu, G., Guo, T., Liang, X. G., Du, H., Yang, L., Bhaduri, A., Li, X., Xu, Z., Zhang, Z., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.03.027 · Cited by 94 · see citing works

Common and Distinct Features of Adult Neurogenesis and Regeneration in the Telencephalon of Zebrafish and Mammals

Diotel, N., Lübke, L., Strähle, U., & Rastegar, S. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.568930 · Cited by 93 · see citing works

Current Understanding of the Neural Stem Cell Niches

Llorente, V., Velarde, P., Desco, M., & Gómez‐Gaviro, M. V. (2022) · Cells · doi:10.3390/cells11193002 · Cited by 94 · see citing works

LRIG1 is a gatekeeper to exit from quiescence in adult neural stem cells

Marqués‐Torrejón, M. Á., Williams, C. A. C., Southgate, B., Alfazema, N., Clements, M., Garcia-Diaz, C., Blin, C., Arranz-Emparan, N., Dudley-Fraser, J., Gammoh, N., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22813-w · Cited by 89 · see citing works

Brain-Protective Mechanisms of Transcription Factor NRF2: Toward a Common Strategy for Neurodegenerative Diseases

Cuadrado, A. (2021) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-052220-103416 · Cited by 86 · see citing works

Declining lamin B1 expression mediates age-dependent decreases of hippocampal stem cell activity

bin Imtiaz, M. K., Jaeger, B. N., Bottes, S., Machado, R. A. C., Vidmar, M., Moore, D. L., & Jessberger, S. (2021) · Cell Stem Cell · doi:10.1016/j.stem.2021.01.015 · Cited by 83 · see citing works

Principles of odor coding in vertebrates and artificial chemosensory systems

Manzini, I., Schild, D., & Natale, C. D. (2021) · Physiological Reviews · doi:10.1152/physrev.00036.2020 · Cited by 84 · see citing works

Oligodendrogenesis and myelination regulate cortical development, plasticity and circuit function

Fletcher, J. L., Makowiecki, K., Cullen, C. L., & Young, K. M. (2021) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2021.03.017 · Cited by 76 · see citing works

Development of the mammalian main olfactory bulb

Tufo, C., Poopalasundaram, S., Dorrego-Rivas, A., Ford, M. C., Graham, A., & Grubb, M. S. (2022) · Development · doi:10.1242/dev.200210 · Cited by 75 · see citing works

Integrated analysis of glycan and RNA in single cells

Minoshima, F., Ozaki, H., Odaka, H., & Tateno, H. (2021) · iScience · doi:10.1016/j.isci.2021.102882 · Cited by 74 · see citing works

Expression Patterns of Inducible Cre Recombinase Driven by Differential Astrocyte-Specific Promoters in Transgenic Mouse Lines

Hu, N.-Y., Chen, Y.-T., Wang, Q., Jie, W., Liu, Y.-S., You, Q.-L., Li, Z., Li, X., Reibel, S., Pfrieger, F. W., et al. (2019) · Neuroscience Bulletin · doi:10.1007/s12264-019-00451-z · Cited by 73 · see citing works

Stem Cells of the Aging Brain

Nicaise, A. M., Willis, C. M., Crocker, S. J., & Pluchino, S. (2020) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2020.00247 · Cited by 73 · see citing works

The multifactorial nature of healthy brain ageing: Brain changes, functional decline and protective factors

Turrini, S., Wong, B., Eldaief, M. C., Press, D. Z., Sinclair, D. A., Koch, G., Avenanti, A., & Santarnecchi, E. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.101939 · Cited by 75 · see citing works

Neural stem cell-derived exosomes-loaded adhesive hydrogel controlled-release promotes cerebral angiogenesis and neurological function in ischemic stroke

Gu, C., Li, Y., Liu, J., Liu, S., Long, J., Zhang, Q., Duan, W., Feng, T., Huang, J., Qiu, Y., et al. (2023) · Experimental Neurology · doi:10.1016/j.expneurol.2023.114547 · Cited by 72 · see citing works

Notch signaling as a master regulator of adult neurogenesis

Lampada, A., & Taylor, V. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1179011 · Cited by 72 · see citing works

Quiescent Neural Stem Cells for Brain Repair and Regeneration: Lessons from Model Systems

Otsuki, L., & Brand, A. H. (2020) · Trends in Neurosciences · doi:10.1016/j.tins.2020.02.002 · Cited by 68 · see citing works

Single-Cell Profiling Shows Murine Forebrain Neural Stem Cells Reacquire a Developmental State when Activated for Adult Neurogenesis

Borrett, M. J., Innes, B. T., Jeong, D., Tahmasian, N., Storer, M. A., Bader, G. D., Kaplan, D. R., & Miller, F. D. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.108022 · Cited by 69 · see citing works

Stress-Related Dysfunction of Adult Hippocampal Neurogenesis—An Attempt for Understanding Resilience?

Leschik, J., Lutz, B., & Gentile, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22147339 · Cited by 70 · see citing works

Radial glia and radial glia-like cells: Their role in neurogenesis and regeneration

Miranda-Negrón, Y., & García‐Arrarás, J. E. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.1006037 · Cited by 69 · see citing works

A periodic table of cell types

Xia, B., & Yanai, I. (2019) · Development · doi:10.1242/dev.169854 · Cited by 66 · see citing works

CRISPR–Cas9 screens reveal regulators of ageing in neural stem cells

Ruetz, T. J., Pogson, A. N., Kashiwagi, C. M., Gagnon, S. D., Morton, B., Sun, E., Na, J., Yeo, R. W., Leeman, D. S., Morgens, D. W., et al. (2024) · Nature · doi:10.1038/s41586-024-07972-2 · Cited by 71 · see citing works

Neurogenesis From Embryo to Adult – Lessons From Flies and Mice

Mira, H., & Morante, J. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00533 · Cited by 64 · see citing works

Accurate RNA velocity estimation based on multibatch network reveals complex lineage in batch scRNA-seq data

Huang, Z., Guo, X., Qin, J., Gao, L., Ju, F., Zhao, C., & Yu, L. (2024) · BMC Biology · doi:10.1186/s12915-024-02085-8 · Cited by 66 · see citing works

Choroid Plexus in Alzheimer’s Disease—The Current State of Knowledge

Gião, T., Teixeira, T., Almeida, M. R., & Cardoso, I. (2022) · Biomedicines · doi:10.3390/biomedicines10020224 · Cited by 64 · see citing works

Translating neural stem cells to neurons in the mammalian brain

Zahr, S. K., Kaplan, D. R., & Miller, F. D. (2019) · Cell Death and Differentiation · doi:10.1038/s41418-019-0411-9 · Cited by 63 · see citing works

Single-Cell Profiling and SCOPE-Seq Reveal Lineage Dynamics of Adult Ventricular-Subventricular Zone Neurogenesis and NOTUM as a Key Regulator

Mizrak, D., Bayin, N. S., Yuan, J., Liu, Z., Suciu, R. M., Niphakis, M. J., Ngo, N., Lum, K. M., Cravatt, B. F., Joyner, A. L., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.107805 · Cited by 59 · see citing works

Dynamic Changes in Ultrastructure of the Primary Cilium in Migrating Neuroblasts in the Postnatal Brain

Matsumoto, M., Sawada, M., García‐González, D., Herranz‐Pérez, V., Ogino, T., Nguyen, H. B., Thai, T. Q., Narita, K., Kumamoto, N., Ugawa, S., et al. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.1503-19.2019 · Cited by 61 · see citing works

Cellular Mechanisms Participating in Brain Repair of Adult Zebrafish and Mammals after Injury

Ghaddar, B., Lübke, L., Couret, D., Rastegar, S., & Diotel, N. (2021) · Cells · doi:10.3390/cells10020391 · Cited by 60 · see citing works

Neural Stem Cells for Early Ischemic Stroke

Hamblin, M. H., & Lee, J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22147703 · Cited by 59 · see citing works

Potential role of NGF, BDNF, and their receptors in oligodendrocytes differentiation from neural stem cell: An in vitro study

Langhnoja, J., Buch, L., & Pillai, P. P. (2020) · Cell Biology International · doi:10.1002/cbin.11500 · Cited by 57 · see citing works

Dynamic spatiotemporal coordination of neural stem cell fate decisions occurs through local feedback in the adult vertebrate brain

Dray, N., Mancini, L., Binshtok, U., Cheysson, F., Supatto, W., Mahou, P., Bedu, S., Ortica, S., Than‐Trong, E., Krecsmarik, M., et al. (2021) · Cell stem cell · doi:10.1016/j.stem.2021.03.014 · Cited by 57 · see citing works

Engineering Tissues of the Central Nervous System: Interfacing Conductive Biomaterials with Neural Stem/Progenitor Cells

Bierman, R. D., Safarians, G., Huang, J., Rajput, B., Chen, J. Y., Wang, Z. Z., & Seidlits, S. K. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202101577 · Cited by 57 · see citing works

Pregnancy-responsive pools of adult neural stem cells for transient neurogenesis in mothers

Chaker, Z., Segalada, C., Kretz, J. A., Acar, İ. E., Delgado, A. C., Crotet, V., Moor, A. E., & Doetsch, F. K. (2023) · Science · doi:10.1126/science.abo5199 · Cited by 52 · see citing works

Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism

Zhao, L., Qiu, Z., Yang, Z., Xu, L., Pearce, T. M., Wu, Q., Yang, K., Li, F.-L., Saulnier, O., Fei, F., et al. (2024) · Nature Cancer · doi:10.1038/s43018-023-00658-0 · Cited by 54 · see citing works

Overlapping migratory mechanisms between neural progenitor cells and brain tumor stem cells

Zarco, N., Norton, E. S., Quiñones‐Hinojosa, A., & Guerrero‐Cazares, H. (2019) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-019-03149-7 · Cited by 52 · see citing works

Effects of Radiation Therapy on Neural Stem Cells

Michaelidesova, A. J., Konířová, J., Bartůněk, P., & Zı́ková, M. (2019) · Genes · doi:10.3390/genes10090640 · Cited by 51 · see citing works

Understanding the effects of air pollution on neurogenesis and gliogenesis in the growing and adult brain

Boda, E., Rigamonti, A. E., & Bollati, V. (2019) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2019.12.003 · Cited by 52 · see citing works

The role of microRNAs in neurobiology and pathophysiology of the hippocampus

Rashidi, S. K., Kalirad, A., Rafie, S., Behzad, E., & Dezfouli, M. A. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2023.1226413 · Cited by 51 · see citing works

DNA Double-Strand Breaks as Pathogenic Lesions in Neurological Disorders

Provasek, V. E., Mitra, J., Malojirao, V. H., & Hegde, M. L. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23094653 · Cited by 51 · see citing works

Potential Mechanisms and Perspectives in Ischemic Stroke Treatment Using Stem Cell Therapies

Zhou, G., Wang, Y., Gao, S., Fu, X., Cao, Y., Peng, Y., Zhuang, J., Hu, J., Shao, A., & Wang, L. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.646927 · Cited by 49 · see citing works

Mercury Toxicity and Neurogenesis in the Mammalian Brain

Abbott, L. C., & Nigussie, F. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22147520 · Cited by 49 · see citing works

Stoichiometric Post‐Modification of Hydrogel Microparticles Dictates Neural Stem Cell Fate in Microporous Annealed Particle Scaffolds

Wilson, K. L., Lesher‐Pérez, S. C., Naffaa, M. M., Kelly, S. H., & Segura, T. (2022) · Advanced Materials · doi:10.1002/adma.202201921 · Cited by 48 · see citing works

Ontogeny of adult neural stem cells in the mammalian brain

Bond, A. M., Ming, G., & Song, H. (2020) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2020.11.002 · Cited by 48 · see citing works

The Symmetry of Neural Stem Cell and Progenitor Divisions in the Vertebrate Brain

Gimeno, G. C., & Paridaen, J. T. M. L. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.885269 · Cited by 45 · see citing works

The impact of adult neurogenesis on affective functions: of mice and men

Alonso, M., Petit, A., & Lledo, P. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02504-w · Cited by 52 · see citing works

Wnt signalling in cell division: from mechanisms to tissue engineering

Habib, S. J., & Acebrón, S. P. (2022) · Trends in Cell Biology · doi:10.1016/j.tcb.2022.05.006 · Cited by 46 · see citing works

Metabolic Regulation of Stem Cells and Differentiation: A Forkhead Box O Transcription Factor Perspective

Ludikhuize, M. C., & Colman, M. J. R. (2020) · Antioxidants and Redox Signaling · doi:10.1089/ars.2020.8126 · Cited by 45 · see citing works

Neural stem/progenitor cell‐derived extracellular vesicles: A novel therapy for neurological diseases and beyond

Li, X., Zhu, Y., Wang, Y., Xia, X., & Zheng, J. (2023) · MedComm · doi:10.1002/mco2.214 · Cited by 44 · see citing works

Adult neurogenesis and “immature” neurons in mammals: an evolutionary trade-off in plasticity?

Bonfanti, L., Rosa, C. L., Ghibaudi, M., & Sherwood, C. C. (2023) · Brain Structure and Function · doi:10.1007/s00429-023-02717-9 · Cited by 46 · see citing works

Implications of neurogenesis in depression through BDNF: rodent models, regulatory pathways, gut microbiota, and potential therapy

Han, H., Yao, J., Wu, J., Mao, S., Pan, H., Qv, L., Zhu, G., Ren, J., Yu, Y., Xuan, F., et al. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03044-7 · Cited by 46 · see citing works

Cyclical fate restriction: a new view of neural crest cell fate specification

Kelsh, R. N., Sosa, K. C., Farjami, S., Makeev, V. J., Dawes, J., & Rocco, A. (2021) · Development · doi:10.1242/dev.176057 · Cited by 42 · see citing works

Advances in 3D printing combined with tissue engineering for nerve regeneration and repair

Liao, W., Shi, Y., Li, Z., & Yin, X. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-03052-9 · Cited by 43 · see citing works

Cilia-driven flows in the brain third ventricle

Gregor Eichele, C., Bodenschatz, E., Ditte, Z., Günther, A.-K., Kapoor, S., Wang, Y., & Westendorf, C. (2019) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2019.0154 · Cited by 41 · see citing works

Restoration of neuronal progenitors by partial reprogramming in the aged neurogenic niche

Xu, L., Ramirez-Matias, J., Hauptschein, M., Sun, E., Lunger, J. C., Buckley, M. T., & Brunet, A. (2024) · Nature Aging · doi:10.1038/s43587-024-00594-3 · Cited by 40 · see citing works

Wnt/β-Catenin Signaling Promotes Differentiation of Ischemia-Activated Adult Neural Stem/Progenitor Cells to Neuronal Precursors

Kriška, J., Janečková, L., Kirdajová, D., Honsa, P., Knotek, T., Džamba, D., Koleničová, D., Butenko, O., Vojtěchová, M., Čapek, M., et al. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.628983 · Cited by 40 · see citing works

Acquired hydrocephalus is associated with neuroinflammation, progenitor loss, and cellular changes in the subventricular zone and periventricular white matter

García‐Bonilla, M., Castañeyra-Ruiz, L., Zwick, S. H., Talcott, M., Otun, A., Isaacs, A. M., Morales, D. M., Limbrick, D. D., & McAllister, J. P. (2022) · Fluids and Barriers of the CNS · doi:10.1186/s12987-022-00313-3 · Cited by 40 · see citing works

DNA damage response in neurodevelopment and neuromaintenance

Qing, X., Zhang, G., & Wang, Z. (2022) · FEBS Journal · doi:10.1111/febs.16535 · Cited by 38 · see citing works

The Subventricular Zone, a Hideout for Adult and Pediatric High-Grade Glioma Stem Cells

Lombard, A., Digregorio, M., Delcamp, C., Rogister, B., Piette, C., & Coppieters, N. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2020.614930 · Cited by 39 · see citing works

HES1 protein oscillations are necessary for neural stem cells to exit from quiescence

Marinopoulou, E., Biga, V., Sabherwal, N., Miller, A., Desai, J., Adamson, A. D., & Papalopulu, N. (2021) · iScience · doi:10.1016/j.isci.2021.103198 · Cited by 33 · see citing works

Lineage Tracing and Cell Potential of Postnatal Single Progenitor Cells In Vivo

Figueres‐Oñate, M., Sánchez-Villalón, M., Sánchez‐González, R., & López‐Mascaraque, L. (2019) · Stem Cell Reports · doi:10.1016/j.stemcr.2019.08.010 · Cited by 37 · see citing works

Integration of millions of transcriptomes using batch-aware triplet neural networks

Simon, L. M., Wang, Y., & Zhao, Z. (2021) · Nature Machine Intelligence · doi:10.1038/s42256-021-00361-8 · Cited by 37 · see citing works

Insulin signaling in development

Suzawa, M., & Bland, M. L. (2023) · Development · doi:10.1242/dev.201599 · Cited by 34 · see citing works

From benzodiazepines to fatty acids and beyond: revisiting the role of ACBP/DBI

Alquier, T., Christian, C. A., Alfonso, J., & Færgeman, N. J. (2021) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2021.08.009 · Cited by 35 · see citing works

GemC1 is a critical switch for neural stem cell generation in the postnatal brain

Lalioti, M., Kaplani, K., Lokka, G., Georgomanolis, T., Kyrousi, C., Dong, W., Dunbar, A., Parlapani, E., Damianidou, E., Spassky, N., et al. (2019) · Glia · doi:10.1002/glia.23690 · Cited by 34 · see citing works

Development of the mammalian cortical hem and its derivatives: the choroid plexus, Cajal–Retzius cells and hippocampus

Moore, S. A., & Iulianella, A. (2021) · Open Biology · doi:10.1098/rsob.210042 · Cited by 35 · see citing works

Fractalkine signaling regulates oligodendroglial cell genesis from SVZ precursor cells

Watson, A. E. S., de Almeida, M. M. A., Dittmann, N. L., Li, Y., Torabi, P., Footz, T. K., Vetere, G., Galleguillos, D., Sipione, S., Cardona, A. E., et al. (2021) · Stem Cell Reports · doi:10.1016/j.stemcr.2021.06.010 · Cited by 34 · see citing works

Irx3 and Irx5 - Novel Regulatory Factors of Postnatal Hypothalamic Neurogenesis

Dou, Z., Son, J. E., & Hui, C. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.763856 · Cited by 35 · see citing works

SoxD genes are required for adult neural stem cell activation

Li, L., Medina-Menéndez, C., García‐Corzo, L., Córdoba-Beldad, C. M., Quiroga, A. C., Barca, E. C., Zinchuk, V., Muñoz-López, S., Rodríguez‐Martín, P., Ciorraga, M., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110313 · Cited by 34 · see citing works

Pediatric Spinal Cord Injury: A Review

Cunha, N., Malvea, A., Sadat, S., Fehlings, M. G., & Ibrahim, G. M. (2023) · Children · doi:10.3390/children10091456 · Cited by 34 · see citing works

An interplay between cellular growth and atypical fusion defines morphogenesis of a modular glial niche in Drosophila

Rujano, M., Briand, D., Ðelić, B., Marc, J., & Spéder, P. (2022) · Nature Communications · doi:10.1038/s41467-022-32685-3 · Cited by 24 · see citing works

Metabolic regulation of the neural stem cell fate: Unraveling new connections, establishing new concepts

Angelopoulos, I., Gakis, G., Birmpas, K., Kyrousi, C., Habeos, E. E., Kaplani, K., Lygerou, Z., Habeos, I. G., & Taraviras, S. L. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.1009125 · Cited by 36 · see citing works

Neurogenesis in the adult hypothalamus: A distinct form of structural plasticity involved in metabolic and circadian regulation, with potential relevance for human pathophysiology

Sharif, A., Fitzsimons, C. P., & Lucassen, P. J. (2021) · Handbook of clinical neurology · doi:10.1016/b978-0-12-819975-6.00006-6 · Cited by 31 · see citing works

Brain aging and rejuvenation at single-cell resolution

Sun, E., Nagvekar, R., Pogson, A. N., & Brunet, A. (2025) · Neuron · doi:10.1016/j.neuron.2024.12.007 · Cited by 33 · see citing works

Tissue Engineering and Biomaterial Strategies to Elicit Endogenous Neuronal Replacement in the Brain

Purvis, E. M., O’Donnell, J. C., Chen, H.-C. I., & Cullen, D. K. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.00344 · Cited by 31 · see citing works

Evidence of the Cellular Senescence Stress Response in Mitotically Active Brain Cells—Implications for Cancer and Neurodegeneration

Gillispie, G. J., Sah, E., Krishnamurthy, S., Ahmidouch, M. Y., Zhang, B., & Orr, M. E. (2021) · Life · doi:10.3390/life11020153 · Cited by 32 · see citing works

Adult neural stem cells stake their ground

Lim, D. A., & Álvarez-Buylla, A. (2014) · Trends in Neurosciences · doi:10.1016/j.tins.2014.08.006 · Cited by 179 · see citing works

A mosaic world: puzzles revealed by adult neural stem cell heterogeneity

Chaker, Z., Codega, P., & Doetsch, F. (2016) · WIREs Developmental Biology · doi:10.1002/wdev.248 · Cited by 198 · see citing works

Editorial: “Unravelling neural stem cell biology: players and strategies”

Sirerol-Piquer, M. S., Morante‐Redolat, J. M., & Porlan, E. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1206339

The Heterogeneity of Adult Neural Stem Cells and the Emerging Complexity of Their Niche

Ohwi, M. K. (2008) · Cited by 1 · see citing works

Neural stem cell heterogeneity in adult hippocampus

Liang, Z., Jin, N., & Guo, W. (2025) · Cell Regeneration · doi:10.1186/s13619-025-00222-4 · Cited by 11 · see citing works