Cited by 226Diabetes Management and ResearchDiabetes Management and EducationDiabetes Treatment and Management

The DOI matches its Crossref record; 18 of the 19 references it cites were found in a registry or an index.

Glycaemic control and severe hypoglycaemia following training in flexible, intensive insulin therapy to enable dietary freedom in people with type 1 diabetes: a prospective implementation study

Open access

Sämann, A., Mühlhauser, I., Bender, R., Kloos, Ch., Müller, U. A.·2005·Diabetologia

DOI 10.1007/s00125-005-1905-1

Open this paper in CoChat — free account Open PDF

Abstract

Aims/hypothesis The aim of this study was to evaluate the implementation of a course teaching flexible, intensive insulin therapy on glycaemic control and severe hypoglycaemia in routine care.Methods This is a continuous quality-assurance project involving hospital diabetes centres. Every third year each centre re-examines 50 consecutive patients (evaluation sample) 1 year after participation in the course. Ninety-six diabetes centres in Germany participated and 9,583 patients with type 1 diabetes (190 evaluation samples) were re-examined between 1992 and 2004. The intervention was a 5-day inpatient course for groups of up to ten patients with a fixed curriculum of education and training for dietary flexibility and insulin adjustment. The main outcome measures were HbA1c and severe hypoglycaemia.Results Mean baseline HbA1c was 8.1%, and had decreased to 7.3% at follow-up; incidence of severe hypoglycaemia was 0.37 events per patient per year prior to intervention and 0.14 after intervention. In mixed-effects models adjusted for effects of centres, age and diabetes duration, the mean difference was -0.7% (95% CI -0.9 to -0.6%, p<0.0001) for HbA1c and -0.21 events per patient per year (95% CI -0.32 to -0.11, p=0.0001) for severe hypoglycaemia, with similar results for evaluation samples, with a maximum of 10% of patients lost to follow-up. Before intervention, the incidence of severe hypoglycaemia was three-fold higher in the lowest quartile than in the highest quartile of HbA1c, whereas the risk was comparable across the range of HbA1c values after intervention.Conclusions/interpretation Implemented as part of a continuous quality-assurance programme the self-management programme is effective and safe in routine care. Improvement of glycaemic control can be achieved without increasing the risk of severe hypoglycaemia.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1007/s00125-005-1905-1

Cites

18 of 18 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus
(1993) · New England Journal of Medicine · doi:10.1056/nejm199309303291401 · Cited by 24,667
Training in flexible, intensive insulin management to enable dietary freedom in people with type 1 diabetes: dose adjustment for normal eating (DAFNE) randomised controlled trial
(2002) · BMJ · doi:10.1136/bmj.325.7367.746 · Cited by 916
Training in flexible, intensive insulin management to enable dietary freedom in people with type 1 diabetes : dose adjustment for normal eating (DAFNE) randomised controlled trial
Amiel, S. A., Beveridge, S., Bradley, C., Gianfrancesco, C., Heller, S. R., James, P., McKeown, N., Newton, D. F., Newton, L. D., Oliver, L., et al. (2002) · Deakin Research Online (Deakin University) · Cited by 723
Diabetes Control and Complications Trial (DCCT): Results of Feasibility Study. The DCCT Research Group
(1987) · Diabetes Care · doi:10.2337/diacare.10.1.1 · Cited by 491
Patient perceptions of diabetes and diabetes therapy: assessing quality of life
Bradley, C., & Speight, J. (2002) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.279 · Cited by 362
Adverse events and their association with treatment regimens in the diabetes control and complications trial
(1995) · Diabetes Care · doi:10.2337/diacare.18.11.1415 · Cited by 305
Bicentric evaluation of a teaching and treatment programme for Type 1 (insulin-dependent) diabetic patients: improvement of metabolic control and other measures of diabetes care for up to 22 months
M�hlhauser, I., J�rgens, V., Berger, M., Graninger, W. B., G�rtler, W., Hörnke, L., Kunz, A., Schernthaner, G., Scholz, V., & Voss, H. E. (1983) · Diabetologia · doi:10.1007/bf00284453 · Cited by 269
Self-citation
Evaluation of an intensified insulin treatment and teaching programme as routine management of Type 1 (insulin-dependent) diabetes
Mühlhauser, I., Bruckner, I. V., Berger, M., Cheţa, D., Jörgens, V., Ionescu-Tirgoviste, C., Scholz, V., & Mincu, I. (1987) · Diabetologia · doi:10.1007/bf00296989 · Cited by 262
Self-citation
Effects of Age, Duration and Treatment of Insulin-Dependent Diabetes Mellitus on Residual β -Cell Function: Observations During Eligibility Testing for the Diabetes Control and Complications Trial (DCCT)
THE DCCT RESEARCH GROUP (1987) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-65-1-30 · Cited by 215
Intensified insulin therapy and the risk of severe hypoglycaemia
Bott, S., Bott, U., Berger, M., & Mühlhauser, I. (1997) · Diabetologia · doi:10.1007/s001250050769 · Cited by 180
Self-citation

Show all 19 references

Sorted by citations

Standards of medical care in diabetes—2014
American Diabetes Association (2014) · Diabetes Care · doi:10.2337/dc14-s014 · Cited by 4,572
Nutrition Therapy for Adults With Diabetes or Prediabetes: A Consensus Report
Evert, A. B., Dennison, M., Gardner, C. D., Garvey, W. T., Lau, K. H. K., MacLeod, J., Mitri, J., Pereira, R. F., Rawlings, K., Robinson, S., et al. (2019) · Diabetes Care · doi:10.2337/dci19-0014 · Cited by 1,496
Clinical Practice Guidelines for Multiple Endocrine Neoplasia Type 1 (MEN1)
Thakker, R. V., Newey, P. J., Walls, G. V., Bilezikian, J. P., Dralle, H., Ebeling, P. R., Melmed, S. K., Sakurai, A., Tonelli, F., & Brandi, M. L. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-1230 · Cited by 1,500
Hypoglycemia and Diabetes: A Report of a Workgroup of the American Diabetes Association and The Endocrine Society
Seaquist, E. R., Anderson, J., Childs, B., Cryer, P., Dagogo-Jack, S., Fish, L., Heller, S. R., Rodriguez, H., Rosenzweig, J., & Vigersky, R. (2013) · Diabetes Care · doi:10.2337/dc12-2480 · Cited by 1,389
“The Insulin Treatment and Training programs developed by M€ uhlhauser and Berger (100) have reported improved glycemic control comparable with DCCT while reducing the rates of severe hypoglycemia (101,102).”
Background
Evaluation and Management of Adult Hypoglycemic Disorders: An Endocrine Society Clinical Practice Guideline
Cryer, P. E., Axelrod, L., Grossman, A. B., Heller, S. R., Montori, V. M., Seaquist, E. R., & Service, F. J. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1410 · Cited by 1,277
Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer
Francis, G. L., Waguespack, S. G., Bauer, A. J., Angelos, P., Benvenga, S., Cerutti, J. M., Dinauer, C., Hamilton, J. K., HAY, I. D., Luster, M., et al. (2015) · Thyroid · doi:10.1089/thy.2014.0460 · Cited by 1,273
Nutrition therapy recommendations for the management of adults with diabetes
Evert, A. B., Boucher, J. L., Cypress, M., Dunbar, S. A., Franz, M. J., Mayer-Davis, E. J., Neumiller, J. J., Nwankwo, R., Verdi, C. L., Urbanski, P., et al. (2013) · Diabetes Care · doi:10.2337/dc13-2042 · Cited by 1,129
Nutrition therapy recommendations for the management of adults with diabetes
Evert, A. B., Boucher, J. L., Cypress, M., Dunbar, S. A., Franz, M. J., Mayer-Davis, E. J., Neumiller, J. J., Nwankwo, R., Verdi, C. L., Urbanski, P., et al. (2014) · Diabetes Care · doi:10.2337/dc14-s120 · Cited by 766
5. Lifestyle Management:Standards of Medical Care in Diabetes—2019
American Diabetes Association (2019) · Diabetes Care · doi:10.2337/dc19-s005 · Cited by 700
Diabetic emergencies - ketoacidosis, hyperglycaemic hyperosmolar state and hypoglycaemia
Umpierrez, G., & Korytkowski, M. (2016) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2016.15 · Cited by 563
4. Lifestyle Management: Standards of Medical Care in Diabetes—2018
American Diabetes Association (2018) · Diabetes Care · doi:10.2337/dc18-s004 · Cited by 563
A rapid synthesis of the evidence on interventions supporting self-management for people with long-term conditions: PRISMS – Practical systematic RevIew of Self-Management Support for long-term conditions
Taylor, S. J., Pinnock, H., Epiphaniou, E., Pearce, G., Parke, H. L., Schwappach, A., Purushotham, N., Jacob, S., Griffiths, C. J., Greenhalgh, T., et al. (2014) · Health Services and Delivery Research · doi:10.3310/hsdr02530 · Cited by 431
Hypoglycemia and Diabetes: A Report of a Workgroup of the American Diabetes Association and The Endocrine Society
Seaquist, E. R., Anderson, J., Childs, B., Cryer, P., Dagogo-Jack, S., Fish, L., Heller, S. R., Rodriguez, H., Rosenzweig, J., & Vigersky, R. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-4127 · Cited by 412
Diabetes structured self-management education programmes: a narrative review and current innovations
Chatterjee, S., Davies, M. J., Heller, S., Speight, J., Snoek, F. J., & Khunti, K. (2018) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(17)30239-5 · Cited by 372
5. Facilitating Positive Health Behaviors and Well-being to Improve Health Outcomes:Standards of Care in Diabetes—2023
ElSayed, N. A., Aleppo, G., Aroda, V. R., Bannuru, R. R., Brown, F. M., Bruemmer, D., Collins, B. S., Hilliard, M. E., Isaacs, D., Johnson, E. L., et al. (2023) · Diabetes Care · doi:10.2337/dc23-s005 · Cited by 362
5. Facilitating Behavior Change and Well-being to Improve Health Outcomes:Standards of Medical Care in Diabetes—2020
(2019) · Diabetes Care · doi:10.2337/dc20-s005 · Cited by 361
5. Facilitating Behavior Change and Well-being to Improve Health Outcomes:Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee (2022) · Diabetes Care · doi:10.2337/dc22-s005 · Cited by 445
Intensive glucose control versus conventional glucose control for type 1 diabetes mellitus
Fullerton, B., Jeitler, K., Seitz, M., Horvath, K., Berghold, A., & Siebenhofer, A. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009122.pub2 · Cited by 299
5. Facilitating Behavior Change and Well-being to Improve Health Outcomes:Standards of Medical Care in Diabetes—2021
American Diabetes Association (2021) · Diabetes Care · doi:10.2337/dc21-s005 · Cited by 299
5. Facilitating Positive Health Behaviors and Well-being to Improve Health Outcomes: Standards of Care in Diabetes—2024
ElSayed, N. A., Aleppo, G., Bannuru, R. R., Beverly, E. A., Bruemmer, D., Collins, B. S., Darville, A. K., Ekhlaspour, L., Hassanein, M. M., Hilliard, M. E., et al. (2023) · Diabetes Care · doi:10.2337/dc24-s005 · Cited by 353
4. Lifestyle Management
American Diabetes Association (2017) · Diabetes Care · doi:10.2337/dc17-s007 · Cited by 281
Improved Biomedical and Psychological Outcomes 1 Year After Structured Education in Flexible Insulin Therapy for People With Type 1 Diabetes
Hopkins, D., Lawrence, I., Mansell, P., Thompson, G., Amiel, S., Campbell, M., & Heller, S. (2012) · Diabetes Care · doi:10.2337/dc11-1579 · Cited by 265
4. Foundations of Care: Education, Nutrition, Physical Activity, Smoking Cessation, Psychosocial Care, and Immunization
American Diabetes Association (2014) · Diabetes Care · doi:10.2337/dc15-s007 · Cited by 269
Evidence-Informed Clinical Practice Recommendations for Treatment of Type 1 Diabetes Complicated by Problematic Hypoglycemia
Choudhary, P., Rickels, M. R., Senior, P. A., Vantyghem, M.-C., Maffi, P., Kay, T. W., Keymeulen, B., Inagaki, N., Saudek, F., Lehmann, R., et al. (2015) · Diabetes Care · doi:10.2337/dc15-0090 · Cited by 233
ISPAD Clinical Practice Consensus Guidelines 2018: Assessment and management of hypoglycemia in children and adolescents with diabetes
Abraham, M. B., Jones, T. W., Naranjo, D. M., Karges, B., Oduwole, A. O., Tauschmann, M., & Maahs, D. M. (2018) · Pediatric Diabetes · doi:10.1111/pedi.12698 · Cited by 232
Ramadan Education and Awareness in Diabetes (READ) programme for Muslims with Type 2 diabetes who fast during Ramadan
Bravis, V., Hui, E., Salih, S., Mehar, S., Hassanein, M. M., & Devendra, D. (2010) · Diabetic Medicine · doi:10.1111/j.1464-5491.2010.02948.x · Cited by 225
Efficacy of carbohydrate counting in type 1 diabetes: A systematic review and meta-analysis
Bell, K. J., Barclay, A. W., Petocz, P., Colagiuri, S., & Brand-Miller, J. C. (2014) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(13)70144-x · Cited by 213
Minimizing Hypoglycemia in Diabetes
International Hypoglycaemia Study Group (2015) · Diabetes Care · doi:10.2337/dc15-0279 · Cited by 216
Metabolic control as reflectet by HbA1c in children, adolescents and young adults with type-1 diabetes mellitus: combined longitudinal analysis including 27,035 patients from 207 centers in Germany and Austria during the last decade
Gerstl, E., Rabl, W., Rosenbauer, J., Gröbe, H., Hofer, S. E., Krause, U., & Holl, R. W. (2007) · European Journal of Pediatrics · doi:10.1007/s00431-007-0586-9 · Cited by 202
Structured Type 1 Diabetes Education Delivered Within Routine Care
Cooke, D., Bond, R., Lawton, J., Rankin, D., Heller, S., Clark, M., Speight, J., & for the U.K. NIHR DAFNE Study Group (2013) · Diabetes Care · doi:10.2337/dc12-0080 · Cited by 156
3. Foundations of Care and Comprehensive Medical Evaluation
American Diabetes Association (2016) · Diabetes Care · doi:10.2337/dc16-s006 · Cited by 159
Interventions that restore awareness of hypoglycemia in adults with type 1 diabetes: A systematic review and meta-analysis
Yeoh, E., Choudhary, P., Nwokolo, M., Ayis, S., & Amiel, S. A. (2015) · Diabetes Care · doi:10.2337/dc15-0102 · Cited by 154
Hemoglobin A1c Levels and Risk of Severe Hypoglycemia in Children and Young Adults with Type 1 Diabetes from Germany and Austria: A Trend Analysis in a Cohort of 37,539 Patients between 1995 and 2012
Karges, B., Rosenbauer, J., Kapellen, T. M., Wagner, V. M., Schober, E., Karges, W., & Holl, R. W. (2014) · PLoS Medicine · doi:10.1371/journal.pmed.1001742 · Cited by 142
Persistent poor glycaemic control in individuals with type 2 diabetes in developing countries: 12 years of real-world evidence of the International Diabetes Management Practices Study (IDMPS)
Montoya, P. A., Gagliardino, J. J., ILKOVA, H. M., Lavalle-Gonzalez, F. J., Ramachandran, A., Mbanya, J. C., Shestakova, M. V., Chantelot, J.-M., & Chan, J. C. N. (2020) · Diabetologia · doi:10.1007/s00125-019-05078-3 · Cited by 130
ISPAD Clinical Practice Consensus Guidelines 2022: Assessment and management of hypoglycemia in children and adolescents with diabetes
Abraham, M. B., Karges, B., Dovč, K., Naranjo, D. M., Arbeláez, A. M., Mbogo, J., Javelikar, G., Jones, T. W., & Mahmud, F. H. (2022) · Pediatric Diabetes · doi:10.1111/pedi.13443 · Cited by 108
Children and adolescents on intensive insulin therapy maintain postprandial glycaemic control without precise carbohydrate counting
Smart, C. E., Ross, K., Edge, J. A., Collins, C. E., Colyvas, K., & King, B. R. (2009) · Diabetic Medicine · doi:10.1111/j.1464-5491.2009.02669.x · Cited by 96
Effects of advanced carbohydrate counting in patients with Type 1 diabetes: a systematic review
Schmidt, S., Schelde, B., & Nørgaard, K. (2014) · Diabetic Medicine · doi:10.1111/dme.12446 · Cited by 94
Patient experience of hypoglycaemia unawareness in Type 1 diabetes: are patients appropriately concerned?
Rogers, H., de Zoysa, N., & Amiel, S. A. (2011) · Diabetic Medicine · doi:10.1111/j.1464-5491.2011.03444.x · Cited by 86
Hypoglycaemia: An overview
Graveling, A. J., & Frier, B. M. (2009) · Primary care diabetes · doi:10.1016/j.pcd.2009.08.007 · Cited by 82
The Role of Dietary Protein and Fat in Glycaemic Control in Type 1 Diabetes: Implications for Intensive Diabetes Management
Paterson, M. A., Bell, K. J., O'Connell, S. M., Smart, C. E., Shafat, A., & King, B. R. (2015) · Current Diabetes Reports · doi:10.1007/s11892-015-0630-5 · Cited by 84
The role of structured education in the management of hypoglycaemia
Iqbal, A., & Heller, S. R. (2018) · Diabetologia · doi:10.1007/s00125-017-4334-z · Cited by 78
A cluster randomised trial, cost-effectiveness analysis and psychosocial evaluation of insulin pump therapy compared with multiple injections during flexible intensive insulin therapy for type 1 diabetes: The repose trial
Heller, S., White, D., Lee, E., Lawton, J., Pollard, D., Waugh, N., Amiel, S., Barnard, K., Beckwith, A., Brennan, A., et al. (2017) · Health Technology Assessment · doi:10.3310/hta21200 · Cited by 73
Influence of and Optimal Insulin Therapy for a Low–Glycemic Index Meal in Children With Type 1 Diabetes Receiving Intensive Insulin Therapy
Ryan, R. L., King, B. R., Anderson, D. G., Attia, J., Collins, C. E., & Smart, C. E. (2008) · Diabetes Care · doi:10.2337/dc08-0331 · Cited by 72
Update in the CNS Response to Hypoglycemia
McCrimmon, R. J. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-1927 · Cited by 72
Practical steps to improving the management of type 1 diabetes: recommendations from the Global Partnership for Effective Diabetes Management
Aschner, P. J., Horton, E., Leiter, L. A., Munro, N. M., Skyler, J. S., & Management*, O. B. O. T. G. P. F. E. D. (2010) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2009.02296.x · Cited by 69
Use of Mobile Health Technology in the Prevention and Management of Diabetes Mellitus
Hartz, J., Yingling, L., & Powell-Wiley, T. M. (2016) · Current Cardiology Reports · doi:10.1007/s11886-016-0796-8 · Cited by 64
Supporting self-management after attending a structured education programme: a qualitative longitudinal investigation of type 1 diabetes patients’ experiences and views
the UK NIHR DAFNE Study Group, Rankin, D., Cooke, D. D., Elliott, D., Heller, S. R., & Lawton, J. (2012) · BMC Public Health · doi:10.1186/1471-2458-12-652 · Cited by 62
Dose adjustment for normal eating (DAFNE)—an audit of outcomes in Australia
McIntyre, H. D., Knight, B. A., Harvey, D. M., Noud, M. N., Hagger, V. L., & Gilshenan, K. S. (2010) · Medical Journal of Australia · doi:10.5694/j.1326-5377.2010.tb03662.x · Cited by 61
Clinical effectiveness of a brief educational intervention in Type 1 diabetes: results from the BITES (Brief Intervention in Type 1 diabetes, Education for Self‐efficacy) trial
George, J. T., Valdovinos, A. P., Russell, I. T., Dromgoole, P., Lomax, S., Torgerson, D. J., Wells, T., & Thow, J. C. (2008) · Diabetic Medicine · doi:10.1111/j.1464-5491.2008.02607.x · Cited by 61
Structured type 1 diabetes education delivered in routine care in Australia reduces diabetes-related emergencies and severe diabetes-related distress: The OzDAFNE program
Speight, J., Holmes‐Truscott, E., Harvey, D. M., Hendrieckx, C., Hagger, V. L., Harris, S. E., Knight, B. A., & McIntyre, D. H. (2015) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2015.11.002 · Cited by 61
Glycated hemoglobin A1c as a risk factor for severe hypoglycemia in pediatric type 1 diabetes: HbA1c and hypoglycemia risk
Karges, B., Kapellen, T., Wagner, V. M., Steigleder-Schweiger, C., Karges, W., Holl, R. W., Rosenbauer, J., & Initiative, F. T. D. (2017) · Pediatric Diabetes · doi:10.1111/pedi.12348 · Cited by 58
Impact of diabetes education and self-management on the quality of care for people with type 1 diabetes mellitus in the Middle East (the International Diabetes Mellitus Practices Study, IDMPS)
Gagliardino, J. J., Chantelot, J.-M., Domenger, C., Ramachandran, A., KADDAHA, G., Mbanya, J. C., Shestakova, M. V., & Chan, J. C. N. (2018) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2018.09.008 · Cited by 60
Managing hypoglycaemia
Iqbal, A., & Heller, S. R. (2016) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2016.06.004 · Cited by 60
The relationship between carbohydrate and the mealtime insulin dose in type 1 diabetes
Bell, K. J., King, B. R., Shafat, A., & Smart, C. E. (2015) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2015.08.014 · Cited by 54
Defective Counterregulation and Hypoglycemia Unawareness in Diabetes
Reno, C. M., Litvin, M., Clark, A. L., & Fisher, S. J. (2012) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2012.11.005 · Cited by 55
Improving management of type 1 diabetes in the UK: the Dose Adjustment For Normal Eating (DAFNE) programme as a research test-bed. A mixed-method analysis of the barriers to and facilitators of successful diabetes self-management, a health economic analysis, a cluster randomised controlled trial of different models of delivery of an educational intervention and the potential of insulin pumps and additional educator input to improve outcomes
Heller, S. R., Lawton, J., Amiel, S. A., Cooke, D. D., Mansell, P., Brennan, A., Elliott, D., Boote, J. D., Emery, C., Baird, W. O., et al. (2014) · Programme Grants for Applied Research · doi:10.3310/pgfar02050 · Cited by 54
Real-life application and validation of flexible intensive insulin-therapy algorithms in type 1 diabetes patients
Franc, S., Dardari, D., Boucherie, B., Riveline, J. P., Biedzinski, M., Petit, C., Requeda, E., Leurent, P., Varroud-Vial, M., Hochberg, G., et al. (2009) · Diabetes & Metabolism · doi:10.1016/j.diabet.2009.05.006 · Cited by 49
Hypoglycaemia: current management and controversies
Choudhary, P., & Amiel, S. A. (2011) · Postgraduate Medical Journal · doi:10.1136/pgmj.2008.068197 · Cited by 49
Reporting Severe Hypoglycemia in Type 1 Diabetes: Facts and Pitfalls
Pedersen‐Bjergaard, U., & Thorsteinsson, B. (2017) · Current Diabetes Reports · doi:10.1007/s11892-017-0965-1 · Cited by 48
Flexible Intensive Insulin Therapy in Adults With Type 1 Diabetes and High Risk for Severe Hypoglycemia and Diabetic Ketoacidosis
Sämann, A., Mühlhauser, I., Bender, R., Hunger-Dathe, W., Kloos, C., & Müller, U. (2006) · Diabetes Care · doi:10.2337/dc06-0751 · Cited by 47
Self-citation
Hypoglycemia
Alsahli, M., & Gerich, J. E. (2013) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2013.07.002 · Cited by 45
Self-adjustment of phosphate binder dose to meal phosphorus content improves management of hyperphosphataemia in children with chronic kidney disease
Ahlenstiel, T., Pape, L., Ehrich, J. H. H., & Kuhlmann, M. K. (2010) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfq161 · Cited by 44
Hypoglycemia: From the Laboratory to the Clinic
Amiel, S. A. (2009) · Diabetes Care · doi:10.2337/dc09-0113 · Cited by 44
Meta-analysis does not allow appraisal of complex interventions in diabetes and hypertension self-management: a methodological review
Lenz, M., Steckelberg, A., Richter, B., & Mühlhauser, I. (2007) · Diabetologia · doi:10.1007/s00125-007-0679-z · Cited by 44
Self-citation
Audit diabetes‐dependent quality of life questionnaire: usefulness in diabetes self‐management education in the Slovak population
Holmanová, E., & Žiaková, K. (2008) · Journal of Clinical Nursing · doi:10.1111/j.1365-2702.2008.02602.x · Cited by 42
Minimizing Hypoglycemia While Maintaining Glycemic Control in Diabetes
Heller, S. R. (2008) · Diabetes · doi:10.2337/db08-1195 · Cited by 40
Impact of a Serious Videogame Designed for Flexible Insulin Therapy on the Knowledge and Behaviors of Children with Type 1 Diabetes: The LUDIDIAB Pilot Study
Joubert, M., Armand, C., Morera, J., Tokayeva, L., Guillaume, A., & Reznik, Y. (2015) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2015.0227 · Cited by 39
DAFNE (Dose Adjustment for Normal Eating): structured education in insulin replacement therapy for type 1 diabetes
McIntyre, D. H. (2006) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.2006.tb00261.x · Cited by 39
A retrospective study on the incidence and risk factors of severe hypoglycemia in primary care
Sämann, A., Lehmann, T., Heller, T., Muller, N., Hartmann, P., Wolf, G., & Müller, U. (2012) · Family Practice · doi:10.1093/fampra/cms071 · Cited by 38
Self-citation
Training in flexible intensive insulin therapy improves quality of life, decreases the risk of hypoglycaemia and ameliorates poor metabolic control in patients with type 1 diabetes
Falconnier, C., Keller, U. B., Moriconi, N., Gessler, A., Schindler, C., Zulewski, H., Ruiz, J., & Puder, J. J. (2009) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2008.11.034 · Cited by 36
Design and Development of a Mobile-Based Self-Care Application for Patients with Type 2 Diabetes
Mehraeen, E., Mehrtak, M., Janfaza, N., Karimi, A., Heydari, M., Mirzapour, P., & Mehranfar, A. (2021) · Journal of Diabetes Science and Technology · doi:10.1177/19322968211007124 · Cited by 40
Clinical Experience with Insulin Glargine in Type 1 Diabetes
Garg, S. K., Moser, E. G., Dain, M., & Rodionova, A. S. (2010) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2010.0135 · Cited by 35
Effects of nutrition education using a food-based approach, carbohydrate counting or routine care in type 1 diabetes: 12 months prospective randomized trial
Sterner Isaksson, S., Bensow Bacos, M., Eliasson, B., Thors Adolfsson, E., Rawshani, A., Lindblad, U., Jendle, J., Berglund, A., Lind, M., & Axelsen, M. (2021) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2020-001971 · Cited by 31
Clinical approaches to treat impaired awareness of hypoglycaemia
Farrell, C. M., & McCrimmon, R. J. (2021) · Therapeutic Advances in Endocrinology and Metabolism · doi:10.1177/20420188211000248 · Cited by 31
Type 1 diabetes structured education: what are the core self‐management behaviours?
Grant, L. M., Lawton, J., Hopkins, D., Elliott, D., Lucas, S. S., Clark, M., MacLellan, I., Davies, M., Heller, S. R., & Cooke, D. D. (2013) · Diabetic Medicine · doi:10.1111/dme.12164 · Cited by 31
Recent Updates on Type 1 Diabetes Mellitus Management for Clinicians
Iqbal, A., Novodvorský, P., & Heller, S. R. (2018) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2018.42.1.3 · Cited by 37
Insulin-pump use in everyday practice: Data from an exhaustive regional registry in France
Riveline, J., Jollois, F.-X., Messaoudi, N., Franc, S., Lagarde, F., Lormeau, B., Charitanski, D., Benoit, A., Pichard, S., Deburge, A., et al. (2008) · Diabetes & Metabolism · doi:10.1016/j.diabet.2007.10.010 · Cited by 32
The effects of diabetes self-management education on quality of life for persons with type 1 diabetes: a systematic review of randomized controlled trials
Davidson, P., LaManna, J., Davis, J., Ojeda, M. M., Hyer, S., Dickinson, J. K., Todd, A., Hammons, T. M., Mohammed Fahim, S., McDaniel, C. C., et al. (2022) · The Science of Diabetes Self-Management and Care · doi:10.1177/26350106211070266 · Cited by 32
Prävalenz der diabetischen Retinopathie
Blum, M., Kloos, C., Muller, N., Mandecka, A., Berner, R., Bertram, B., & Müller, U. (2007) · Der Ophthalmologe · doi:10.1007/s00347-007-1522-0 · Cited by 30
Self-citation
Hypoglycaemia.
Muneer, M. (2020) · Advances in Experimental Medicine and Biology · doi:10.1007/5584_2020_534 · Cited by 28
Frequency of blood glucose testing in well educated patients with diabetes mellitus type 1: how often is enough?
Minder, A. E., Albrecht, D., Schäfer, J., & Zulewski, H. (2013) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2012.12.024 · Cited by 28
Multiple Daily Injections OR Insulin Pump Therapy: Choosing the Best Option for Your Patient—An Evidence-based Approach
Joshi, M., & Choudhary, P. (2015) · Current Diabetes Reports · doi:10.1007/s11892-015-0644-z · Cited by 29
Blood Glucose Pattern Management in Diabetes: Creating Order from Disorder
Choudhary, P., Genovese, S., & Reach, G. (2013) · Journal of Diabetes Science and Technology · doi:10.1177/193229681300700618 · Cited by 28
The Irish DAFNE Study Protocol: A cluster randomised trial of group versus individual follow-up after structured education for Type 1 diabetes
the Irish DAFNE Study Group, Dinneen, S. F., Hara, M. C. O., Byrne, M., Newell, J., Daly, L., Shea, D. O., & Smith, D. (2009) · Trials · doi:10.1186/1745-6215-10-88 · Cited by 27
Physical activity level and exercise in patients with diabetes mellitus
Duarte, C. K., de Almeida, J. C., Merker, A. J. S., Brauner, F. D. O., & Rodrigues, T. D. C. (2012) · Revista da Associação Médica Brasileira (English Edition) · doi:10.1016/s2255-4823(12)70183-2 · Cited by 27
Effects of advanced carbohydrate counting on glucose control and quality of life in children with type 1 diabetes
Donzeau, A., Bonnemaison, É., Vautier, V., Menut, V., Houdon, L., Bendelac, N., Bismuth, É., Bouhours‐Nouet, N., Quemener, E., Baron, S., et al. (2020) · Pediatric Diabetes · doi:10.1111/pedi.13076 · Cited by 25
Evaluation of a Blood Glucose Monitoring System with Automatic High- and Low-Pattern Recognition Software in Insulin-Using Patients: Pattern Detection and Patient-Reported Insights
Grady, M., Campbell, D. J., MacLeod, K., & Srinivasan, A. (2013) · Journal of Diabetes Science and Technology · doi:10.1177/193229681300700419 · Cited by 24
Knowledge after five-day teaching program in intensive insulin therapy performed at the onset of type 1 diabetes influence the development of late diabetic complications
Araszkiewicz, A., Zozulińska‐Ziółkiewicz, D., Trepińska, M. M., & Wierusz‐Wysocka, B. (2008) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2008.02.009 · Cited by 23
Evaluation of a treatment and teaching refresher programme for the optimization of intensified insulin therapy in type 1 diabetes
Muller, N., Kloos, C., Sämann, A., Wolf, G., & Müller, U. (2013) · Patient Education and Counseling · doi:10.1016/j.pec.2013.05.008 · Cited by 23
Self-citation
The Relative Effectiveness of Pumps Over MDI and Structured Education (REPOSE): study protocol for a cluster randomised controlled trial
White, D. A., Waugh, N. R., Elliott, J., Lawton, J., Barnard-Kelly, K. D., Campbell, M. J., Dixon, S., & Heller, S. R. (2014) · BMJ Open · doi:10.1136/bmjopen-2014-006204 · Cited by 22
Hub‐and‐spoke model for a 5‐day structured patient education programme for people with Type 1 diabetes
Rogers, H., Turner, E., Thompson, G., Hopkins, D., & Amiel, S. A. (2009) · Diabetic Medicine · doi:10.1111/j.1464-5491.2009.02796.x · Cited by 22
Update on strategies limiting iatrogenic hypoglycemia
Bonaventura, A., Montecucco, F., & Dallegri, F. (2015) · Endocrine Connections · doi:10.1530/ec-15-0044 · Cited by 22
Nível de atividade física e exercício físico em pacientes com diabetes mellitus
Duarte, C. K., de Almeida, J. C., Merker, A. J. S., Brauner, F. D. O., & Rodrigues, T. D. C. (2012) · Revista da Associação Médica Brasileira · doi:10.1590/s0104-42302012000200018 · Cited by 21
Hypoglycemia During Therapy of Diabetes
Spanakis, E. K., Cryer, P. E., & Davis, S. N. (2015) · Europe PMC (PubMed Central) · Cited by 21
Effectiveness of Dose Adjustment for Normal Eating (DAFNE)
Owen, C., & Woodward, S. (2012) · British Journal of Nursing · doi:10.12968/bjon.2012.21.4.224 · Cited by 21
Structured education in type 1 diabetes
Heller, S. R. (2009) · The British Journal of Diabetes · doi:10.1177/1474651409351646 · Cited by 21
Conversations and Reactions Around Severe Hypoglycemia Study: Results of Hypoglycemia Experiences in Canadian Adults With Insulin-Treated Diabetes and Their Caregivers
Mojdami, D., Mitchell, B. D., Spaepen, E., Syring, K. E., RABASA-LHORET, R. P. R., Punthakee, Z., Snoek, F. J., & Peyrot, M. F. (2020) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2020.08.104 · Cited by 21
Diabetes mellitus type 1 in adults
Dedov, I. I., Shestakova, M. V., Mayorov, A. Y., Шамхалова, М. Ш., Nikonova, T. V., Sukhareva, O. Y., Пекарева, Е. В., Ibragimova, L. I., Mikhina, M. S., Galstyan, G. R., et al. (2020) · Diabetes Mellitus · doi:10.14341/dm12505 · Cited by 19
The Impact of Hypoglycemia on Patients with Diabetes Mellitus: A Cross-Sectional Analysis
Agrawal, S., Makuch, S., Dróżdż, M., Dudzik, T., Domański, I., Poręba, R., & Mazur, G. J. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11030626 · Cited by 21
Current and future therapies to treat impaired awareness of hypoglycemia
Macon, E. L., DEVORE, M. H., Lin, Y. K., MUSIC, M. B., WOOTEN, M., McMullen, C. A., Woodcox, A. M., MARKSBURY, A. R., Beckner, Z., Patel, B. V., et al. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1271814 · Cited by 20

Authors: Sämann, A., Mühlhauser, I., Bender, R., Kloos, C., & Müller, U. A.
Affiliations: Universität Hamburg (DE)
Institute for Quality and Efficiency in Health Care (DE)
Friedrich Schiller University Jena (DE)
ORCID: Müller, U. A.
Venue: Diabetologia
Publisher: Springer Science and Business Media LLC
Published: 2005-08-18
Volume: 48
Issue: 10
Pages: 1965-1970
ISSN: 0012-186X (ISSN-L)
1432-0428
DOI: 10.1007/s00125-005-1905-1
OpenAlex: W1991647428
Cited by: 226
References: 19
Citations by year: 2026: 1 · 2025: 3 · 2024: 3 · 2023: 2 · 2022: 12 · 2021: 6 · 2020: 8 · 2019: 10 · 2018: 6 · 2017: 12 · 2016: 13 · 2015: 19 · 2014: 20 · 2013: 20 · 2012: 21
FWCI: 7.87
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.springer.com/tdm (tdm)
Locations: Diabetologia (publishedVersion)
PubMed (publishedVersion)
Funders: Eli Lilly and Company
Sanofi
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
Keywords: type 1 diabetes, intensive insulin therapy, glycemic control, HbA1c, severe hypoglycemia, diabetes self-management education, quality assurance, insulin dose adjustment
MeSH terms: Adult, Blood Glucose, Diabetes Mellitus, Type 1, Diet, Female, Germany, Glycated Hemoglobin, Humans, Hypoglycemia, Hypoglycemic Agents, Insulin, Male, Patient Education as Topic, Prospective Studies, Treatment Outcome, Total Quality Management

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Glycaemic control and severe hypoglycaemia following training in flexible, intensive insulin therapy to enable dietary freedom in people with type 1 diabetes: a prospective implementation study

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks