Incidence and management of graft erosion, wound granulation, and dyspareunia following vaginal prolapse repair with graft materials: a systematic review

For the Systematic Review Group of the Society of Gynecologic Surgeons; Abed, Husam; Rahn, David D.; Lowenstein, Lior; Balk, Ethan M.; Clemons, Jeffrey L.; Rogers, Rebecca G.

doi:10.1007/s00192-011-1384-5

Cited by 295Pelvic floor disorders treatmentsHernia repair and managementUterine Myomas and Treatments

Incidence and management of graft erosion, wound granulation, and dyspareunia following vaginal prolapse repair with graft materials: a systematic review

For the Systematic Review Group of the Society of Gynecologic Surgeons, Abed, Husam, Rahn, David D., Lowenstein, Lior, Balk, Ethan M., Clemons, Jeffrey L., Rogers, Rebecca G.·2011·International Urogynecology Journal

DOI 10.1007/s00192-011-1384-5

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Abstract

Introduction and hypothesis This study describes the incidence, risk factors, and treatments of graft erosion, wound granulation, and dyspareunia as adverse events following vaginal repair of pelvic organ prolapse with non-absorbable synthetic and biologic graft materials.Methods A systematic review in Medline of reports published between 1950 and November 2010 on adverse events after vaginal prolapse repairs using graft materials was carried out.Results One hundred ten studies reported on erosions with an overall rate, by meta-analysis, of 10.3%, (95% CI, 9.7 - 10.9%; range, 0 - 29.7%; synthetic, 10.3%; biological, 10.1%). Sixteen studies reported on wound granulation for a rate of 7.8%, (95% CI, 6.4 - 9.5%; range, 0 - 19.1%; synthetic, 6.8%; biological, 9.1%). Dyspareunia was described in 70 studies for a rate of 9.1%, (95% CI, 8.2 - 10.0%; range, 0 - 66.7%; synthetic, 8.9%; biological, 9.6%).Conclusions Erosions, wound granulation, and dyspareunia may occur after vaginal prolapse repair with graft materials, though rates vary widely across studies.

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Polypropylene mesh produces a high level of anatomical cure (90% or more) in the treatment of pelvic organ prolapse.
“Although PP produces a high level of anatomical cure (90% or more), it is associated with a significant incidence of erosions and other complications, such as continuing pain, leading to dyspareunia [55].”
From How Can We Improve the Assessment and Indifferent Outcomes From Pelvic Organ Prolapse Management From Conservative and Surgical Therapies? ICI‐RS 2025 (2026) · cites this paper as [55]
Polypropylene mesh implanted into the pelvic floor, particularly for the treatment of pelvic organ prolapse, causes significant complications in a proportion of patients.
“It is now well‐established that there are significant complications in a proportion of patients when polypropylene mesh (PP) is implanted into the pelvic floor, particularly when used for the treatment of POP.”
From How Can We Improve the Assessment and Indifferent Outcomes From Pelvic Organ Prolapse Management From Conservative and Surgical Therapies? ICI‐RS 2025 (2026) · cites this paper as [55]
Polypropylene mesh is associated with a significant incidence of erosions and other complications, such as continuing pain leading to dyspareunia, in the treatment of pelvic organ prolapse.
“Although PP produces a high level of anatomical cure (90% or more), it is associated with a significant incidence of erosions and other complications, such as continuing pain, leading to dyspareunia [55].”
From How Can We Improve the Assessment and Indifferent Outcomes From Pelvic Organ Prolapse Management From Conservative and Surgical Therapies? ICI‐RS 2025 (2026) · cites this paper as [55]

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Authors: For the Systematic Review Group of the Society of Gynecologic Surgeons, Abed, H., Rahn, D. D., Lowenstein, L., Balk, E. M., Clemons, J. L., & Rogers, R. G.
Affiliations: Henry Ford Health (US)
Technion – Israel Institute of Technology (IL)
Tufts Medical Center (US)
Madigan Army Medical Center (US)
University of New Mexico Health Sciences Center (US)
Corresponding author: Abed, Husam
ORCID: Rahn, David D.
Balk, Ethan M.
Rogers, Rebecca G.
Venue: International Urogynecology Journal
Publisher: Springer Science and Business Media LLC
Published: 2011-03-22
Volume: 22
Issue: 7
Pages: 789-798
ISSN: 0937-3462 (ISSN-L)
1433-3023
DOI: 10.1007/s00192-011-1384-5
OpenAlex: W2060570186
Cited by: 295
References: 29
Citations by year: 2026: 7 · 2025: 10 · 2024: 11 · 2023: 10 · 2022: 13 · 2021: 19 · 2020: 13 · 2019: 26 · 2018: 18 · 2017: 18 · 2016: 26 · 2015: 31 · 2014: 22 · 2013: 28 · 2012: 37
FWCI: 4.37
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: International Urogynecology Journal (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Rheumatology › Pelvic floor disorders treatments
Health Sciences › Medicine › Surgery › Hernia repair and management
Health Sciences › Medicine › Obstetrics and Gynecology › Uterine Myomas and Treatments
Keywords: vaginal prolapse repair, wound granulation, dyspareunia, pelvic organ prolapse, adverse events, incidence, risk factors
MeSH terms: Dyspareunia, Female, Granulation Tissue, Humans, Postoperative Complications, Surgical Mesh, Vagina, Incidence, Pelvic Organ Prolapse

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Incidence and management of graft erosion, wound granulation, and dyspareunia following vaginal prolapse repair with graft materials: a systematic review

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