The DOI matches its Crossref record; 87 of the 94 references it cites were found in a registry or an index.
Environmental and cultural stimulants in the production of carotenoids from microorganisms
Abstract
Commercial production of carotenoids from microorganisms competes mainly with synthetic manufacture by chemical procedures. Efficient stimulation of carotenoid biosynthesis is expected to promote accumulation of carotenoid by microbes. This review describes the variety of environmental and cultural stimulants studied during the last few decades which enhance volumetric production and cellular accumulation of commercially important carotenoids from microalgae, fungi and bacteria. Stimulation of carotenoid production by white-light illumination and temperature fluctuation is discussed along with supplementation of metal ions, salts, organic solvents, preformed precursors and several other chemicals in the culture broth. Reports on the improvements in yield are reviewed and assessed from a biotechnology point of view.
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“Some microalgae are capable of generating high amounts of carotenes in response to external stimuli that cause stress, so that they can adapt to new changes [150].”
From The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value (2019) · cites this paper as [150]
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Metadata
- Authors
- Bhosale, P.
- Affiliations
- University of Utah (US)
- Corresponding author
- Bhosale, P.
- Venue
- Applied Microbiology and Biotechnology
- Published
- 2004-01-01
- Volume
- 63
- Issue
- 4
- Pages
- 351-361
- ISSN
- 0175-7598 (ISSN-L)
- 1432-0614
- OpenAlex
- W2008784761
- Cited by
- 341
- References
- 94
- Citations by year
- 2026: 10 · 2025: 16 · 2024: 18 · 2023: 19 · 2022: 23 · 2021: 23 · 2020: 24 · 2019: 18 · 2018: 12 · 2017: 16 · 2016: 13 · 2015: 17 · 2014: 18 · 2013: 21 · 2012: 15
- FWCI
- 7.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Applied Microbiology and Biotechnology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Microbial Metabolism and Applications
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Keywords
- carotenoid production, microbial carotenoids, microalgae, fungi, bacteria, white light illumination, temperature fluctuations, metal ions, organic solvents, precursors, carotenoid biosynthesis, carotenoid accumulation
- MeSH terms
- Bacteria, Biotechnology, Carotenoids, Culture Media, Fungi, Light, Temperature, Bioreactors, Eukaryota
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