MR angiography with blood pool contrast agents
Abstract
Contrast-enhanced magnetic resonance angiography (CE-MRA) with standard extracellular contrast material is well established for vascular imaging. Recently, the first blood pool contrast agent (BPA) has become clinically available. This paper reviews characteristics and classification of BPA as well as first clinical experience in various vascular territories. BPAs comprise gadolinium-based compounds, synthetic compounds, and ultrasmall superparamagnetic iron-oxide (USPIO) particles. Such BPAs are retained in blood with a prolonged time-window of enhancement as compared to extracellular gadolinium chelates. Promising results from USPIO at first-pass and steady-state angiography have been published, but no USPIO is approved yet. Gadofosveset is the first clinically approved BPA. After bolus injection, gadofosveset binds noncovalently to serum-albumine, thus enhancing relaxivity. First published results from carotid, coronary, renal, and peripheral angiography are encouraging; particularly helpful is prolonged enhancement during steady state. More BPAs have been clinically evaluated, but no approval has been granted. Bolus-injectable BPAs allow for first-pass CE-MRA similar to standard extracellular contrast media, but with higher relaxivity, allowing lower doses and reduced injection rates. An additional feature of BPA is the steady-state phase with a broad time window enabling high-resolution angiography or double-gated angiography of coronary arteries to compensate for the complex motion pattern.
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Rohrer, M., Bauer, H., Mintorovitch, J., Requardt, M., & Weinmann, H. (2005) · Investigative Radiology · doi:10.1097/01.rli.0000184756.66360.d3 · Cited by 1,681 · see citing works
Weissleder, R., & Mahmood, U. (2001) · Radiology · doi:10.1148/radiology.219.2.r01ma19316 · Cited by 1,315 · see citing works
Nephrogenic Systemic Fibrosis: Risk Factors and Incidence Estimation
Sadowski, E. A., Bennett, L. K., Chan, M. R., Wentland, A. L., Garrett, A. L., Garrett, R. W., & Djamali, A. (2007) · Radiology · doi:10.1148/radiol.2431062144 · Cited by 1,011 · see citing works
A Preliminary Report Comparing Magnetic Resonance Coronary Angiography with Conventional Angiography
Manning, W. J., Li, W., & Edelman, R. R. (1993) · New England Journal of Medicine · doi:10.1056/nejm199303253281202 · Cited by 547 · see citing works
MS-325: albumin-targeted contrast agent for MR angiography.
Lauffer, R. B., Parmelee, D. J., Dunham, S. U., Ouellet, H. S., Dolan, R. P., Witte, S., McMurry, T. J., & Walovitch, R. C. (1998) · Radiology · doi:10.1148/radiology.207.2.9577506 · Cited by 457 · see citing works
Functional tumor imaging with dynamic contrast‐enhanced magnetic resonance imaging
Choyke, P. L., Dwyer, A. J., & Knopp, M. V. (2003) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.10304 · Cited by 440 · see citing works
Diagnostic Tests for Renal Artery Stenosis in Patients Suspected of Having Renovascular Hypertension
Vasbinder, G. B. C., Nelemans, P. J., Kessels, A. G. H., Kroon, A. A., de Leeuw, P. W., & van Engelshoven, J. M. A. (2001) · Annals of Internal Medicine · doi:10.7326/0003-4819-135-6-200109180-00009 · Cited by 380 · see citing works
Vasbinder, G. B. C., Nelemans, P. J., Kessels, A. G. H., Kroon, A. A., Maki, J. H., Leiner, T., Beek, F. J. A., Korst, M. B. J. M., Flobbe, K., de Haan, M. W., et al. (2004) · Annals of Internal Medicine · doi:10.7326/0003-4819-141-9-200411020-00007 · Cited by 361 · see citing works
Nephrogenic systemic fibrosis: a serious late adverse reaction to gadodiamide
Thomsen, H. S. (2006) · European Radiology · doi:10.1007/s00330-006-0495-8 · Cited by 352 · see citing works
Ogan, M. D., Schmiedl, U. P., Moseley, M. E., Grodd, W., Paajanen, H., & Brasch, R. C. (1987) · Investigative Radiology · doi:10.1097/00004424-198708000-00008 · Cited by 275 · see citing works
Kobayashi, H., Kawamoto, S., Jo, S.-K., Bryant, H. L., Brechbiel, M. W., & Star, R. A. (2003) · Bioconjugate Chemistry · doi:10.1021/bc025633c · Cited by 262 · see citing works
Rationale and applications for macromolecular Gd‐based contrast agents
Brasch, R. C. (1991) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910220225 · Cited by 161 · see citing works
Pharmacokinetics of Gadomer-17, a new dendritic magnetic resonance contrast agent
Misselwitz, B., Schmitt‐Willich, H., Ebert, W., Frenzel, T., & Weinmann, H. (2001) · Magnetic Resonance Materials in Physics Biology and Medicine · doi:10.1007/bf02668094 · Cited by 158 · see citing works
Taupitz, M., Wagner, S., Schnorr, J., Kravec, I., Pilgrimm, H., Bergmann-Fritsch, H., & Hamm, B. (2004) · Investigative Radiology · doi:10.1097/01.rli.0000129472.45832.b0 · Cited by 157 · see citing works
Lawaczeck, R., Bauer, H., Frenzel, T., Hasegawa, M., Ito, Y., Kito, K., Miwa, N., TSUTSUI, H., Vogler, H., & Weinmann, H. J. (1997) · Acta Radiologica · doi:10.1080/02841859709174391 · Cited by 148 · see citing works
Allkemper, T., Bremer, C., Matuszewski, L., Ebert, W., & Reimer, P. (2002) · Radiology · doi:10.1148/radiol.2232010241 · Cited by 124 · see citing works
Self-citationSchoenberg, S. O., Rieger, J., Weber, C. H., Michaely, H. J., Waggershauser, T., Ittrich, C., Dietrich, O., & Reiser, M. F. (2005) · Radiology · doi:10.1148/radiol.2352031693 · Cited by 115 · see citing works
Nikolaou, K., Kramer, H., Grosse, C., Clevert, D., Dietrich, O., Hartmann, M., Chamberlin, P., Assmann, S., Reiser, M. F., & Schoenberg, S. O. (2006) · Radiology · doi:10.1148/radiol.2413060053 · Cited by 102 · see citing works
Critical Limb Ischemia: Hybrid MR Angiography Compared with DSA
Meissner, O. A., Rieger, J., Weber, C. H., Siebert, U., Steckmeier, B., Reiser, M. F., & Schoenberg, S. O. (2005) · Radiology · doi:10.1148/radiol.2343031685 · Cited by 95 · see citing works
Carotid MR Angiography: Phase II Study of Safety and Efficacy for MS-325
Bluemke, D. A., Stillman, A. E., Bis, K. G., Grist, T. M., Baum, R. A., D’Agostino, R., Malden, E. S., Pierro, J. A., & Yucel, E. K. (2001) · Radiology · doi:10.1148/radiology.219.1.r01ap42114 · Cited by 83 · see citing works
Coronary Arteries: Contrast-enhanced MR Imaging with SH L 643A—Experience in 12 Volunteers
Herborn, C. U., Barkhausen, J., Paetsch, I., Hunold, P., Mahler, M., Shamsi, K., & Nagel, E. C. (2003) · Radiology · doi:10.1148/radiol.2291021033 · Cited by 75 · see citing works
Assessment of Gadobenate Dimeglumine for Magnetic Resonance Angiography
Knopp, M. V., Schoenberg, S. O., REHM, C., Floemer, F., von Tengg‐Kobligk, H., Bock, M., & Hentrich, H. (2002) · Investigative Radiology · doi:10.1097/00004424-200212000-00011 · Cited by 73 · see citing works
Wyttenbach, R., Gianella, S., Alerci, M., Braghetti, A., Cozzi, L., & Gallino, A. (2003) · Radiology · doi:10.1148/radiol.2271011989 · Cited by 70 · see citing works
MR angiography with gadofosveset trisodium for peripheral vascular disease: phase II trial.
Perreault, P., Edelman, M. A., Baum, R., Yucel, E., Weisskoff, R., Shamsi, K., & Mohler, E. (2003) · Radiology · doi:10.1148/radiol.2293021180 · Cited by 67 · see citing works
Tombach, B., Reimer, P., Bremer, C., Allkemper, T., Engelhardt, M., Mahler, M., Ebert, W., & Heindel, W. L. (2004) · NMR in Biomedicine · doi:10.1002/nbm.906 · Cited by 63 · see citing works
Self-citationA Summary of Safety of Gadofosveset (MS-325) at 0.03 mmol/kg Body Weight Dose
Shamsi, K., Yucel, E. K., & Chamberlin, P. (2006) · Investigative Radiology · doi:10.1097/01.rli.0000242836.25299.8f · Cited by 57 · see citing works
Schnorr, J., Wagner, S., Abramjuk, C., Wojner, I., Schink, T., Kroencke, T. J., Schellenberger, E., Hamm, B., Pilgrimm, H., & Taupitz, M. (2004) · Investigative Radiology · doi:10.1097/01.rli.0000133944.30119.cc · Cited by 54 · see citing works
Comparison of Two Blood Pool Contrast Agents for 0.5-T MR Angiography: Experimental Study in Rabbits
Clarke, S. E., Weinmann, H.-J., Dai, E., Lucas, A., & Rutt, B. K. (2000) · Radiology · doi:10.1148/radiology.214.3.r00mr25787 · Cited by 53 · see citing works
Expanding role of MR angiography in clinical practice
Prince, M. R., & Meaney, J. F. (2006) · European Radiology Supplements · doi:10.1007/s10406-006-0161-x · Cited by 50 · see citing works
Reimer, P., Bremer, C., Allkemper, T., Engelhardt, M., Mahler, M., Ebert, W., & Tombach, B. (2004) · Radiology · doi:10.1148/radiol.2312021251 · Cited by 49 · see citing works
Self-citationImmunogenicity of Gadolinium-Based Contrast Agents for Magnetic Resonance Imaging
BAXTER, A. B., MELNIKOFF, S., Stites, D. P., & Brasch, R. C. (1991) · Investigative Radiology · doi:10.1097/00004424-199112000-00001 · Cited by 46 · see citing works
Schmiedl, U. P., Brasch, R. C., Ogan, M., & Moseley, M. E. (1990) · PubMed · Cited by 44 · see citing works
Wacker, F. K., Reither, K., Ebert, W., Wendt, M., Lewin, J. S., & Wolf, K.-J. (2003) · Radiology · doi:10.1148/radiol.2262011815 · Cited by 40 · see citing works
MR Coronary Angiography with SH L 643 A: Initial Experience in Patients with Coronary Artery Disease
Herborn, C. U., Schmidt, M., Bruder, O., Nagel, E. C., Shamsi, K., & Barkhausen, J. (2004) · Radiology · doi:10.1148/radiol.2332031545 · Cited by 33 · see citing works
Effect of Field Strengths on Magnetic Resonance Angiography
Allkemper, T., Heindel, W. L., Kooijman, H., Ebert, W., & Tombach, B. (2006) · Investigative Radiology · doi:10.1097/01.rli.0000194779.02079.ce · Cited by 31 · see citing works
Daldrup-Link, H. E., Kaiser, A., Helbich, T. H., Werner, M., Bjørnerud, A., Link, T. M., & Rummeny, E. J. (2003) · Academic Radiology · doi:10.1016/s1076-6332(03)00248-4 · Cited by 28 · see citing works
Zheng, J., Carr, J., Harris, K., Saker, M. B., CAVAGNA, F. M., Maggioni, F., Laub, G. A., Li, D., & Finn, J. P. (2001) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.1203 · Cited by 24 · see citing works
First-Pass and Equilibrium Phase MRA Following Intravenous Bolus Injection of SH U 555 C
Tombach, B., Reimer, P., Mahler, M., Ebert, W., Pering, C., & Heindel, W. L. (2002) · Academic Radiology · doi:10.1016/s1076-6332(03)80251-9 · Cited by 22 · see citing works
Self-citationBilecen, D., Jäger, K., Aschwanden, M., Heidecker, H. G., Schulte, A., & Bongartz, G. M. (2004) · Acta Radiologica · doi:10.1080/02841850410005921 · Cited by 20 · see citing works
Self-citationUtilizing SENSE to reduce scan duration in high‐resolution contrast‐enhanced renal MR angiography
Wilson, G. J., Eubank, W. B., Vasbinder, G. B. C., Kessels, A. G. H., Hoogeveen, R. M., Muthupillai, R., & Maki, J. H. (2006) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.20691 · Cited by 19 · see citing works
Burtéa, C., Laurent, S., Colet, J., Elst, L. V., & Müller, R. N. (2003) · Investigative Radiology · doi:10.1097/01.rli.0000066251.65982.e6 · Cited by 14 · see citing works
Bonk, R. T., Schmiedl, U. P., Yuan, C., Nelson, J. A., BLACK, C. D. V., & Ladd, D. L. (2000) · Journal of Magnetic Resonance Imaging · doi:10.1002/1522-2586(200006)11:6 · Cited by 10 · see citing works
Self-citationSpatial regularization of flow patterns in magnetic resonance velocity mapping
Herment, A., Mousseaux, É., Cesare, A. D., Jolivet, O., Dumée, P., Todd-Pokropek, A. E., & Bittoun, J. (1999) · Journal of Magnetic Resonance Imaging · doi:10.1002/(sici)1522-2586(199911)10:5 · Cited by 3 · see citing works
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Dadfar, S. M., Roemhild, K., Drude, N. I., von Stillfried, S., Knüchel, R., Kiessling, F., & Lammers, T. (2019) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2019.01.005 · Cited by 1,181 · see citing works
Kim, B. H., Lee, N., Kim, H., An, K., Park, Y. I., Choi, Y., Shin, K., Lee, Y., Kwon, S. G., Na, H. B., et al. (2011) · Journal of the American Chemical Society · doi:10.1021/ja203340u · Cited by 948 · see citing works
Interactions of nanomaterials and biological systems: Implications to personalized nanomedicine
Zhang, X., Xu, X., Bertrand, N., Pridgen, E. M., Swami, A., & Farokhzad, O. C. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.08.005 · Cited by 494 · see citing works
25 Years of Contrast-Enhanced MRI: Developments, Current Challenges and Future Perspectives
Lohrke, J., Frenzel, T., Endrikat, J., Caseiro‐Alves, F., Grist, T. M., Law, M., Lee, J. M., Leiner, T., Li, K.-C., Nikolaou, K., et al. (2016) · Advances in Therapy · doi:10.1007/s12325-015-0275-4 · Cited by 420 · see citing works
Emerging applications for ferumoxytol as a contrast agent in MRI
Bashir, M. R., Bhatti, L., Marin, D., & Nelson, R. C. (2014) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.24691 · Cited by 373 · see citing works
Jin, R., Lin, B., Li, D., & Ai, H. (2014) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2014.08.002 · Cited by 305 · see citing works
Neuwelt, E. A., Hamilton, B. E., Varallyay, C. G., Rooney, W. R., Edelman, R. D., Jacobs, P. M., & Watnick, S. G. (2009) · Kidney International · doi:10.1038/ki.2008.496 · Cited by 267 · see citing works
Therapeutic Nanoparticles in Clinics and Under Clinical Evaluation
Schütz, C. A., Juillerat‐Jeanneret, L., Mueller, H., Lynch, I., & Riediker, M. (2013) · Nanomedicine · doi:10.2217/nnm.13.8 · Cited by 241 · see citing works
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Sakamoto, J. H., van de Ven, A. L., Godin, B., Blanco, E., Serda, R. E., Grattoni, A., Žiemys, A., Bouamrani, A., Hu, Y., Ranganathan, S. I., et al. (2010) · Pharmacological Research · doi:10.1016/j.phrs.2009.12.011 · Cited by 228 · see citing works
Zhang, H., Li, L., Liu, X., Jiao, J., Ng, C.-T., Yi, J. B., Luo, Y., Bay, B., Zhao, L., Peng, M., et al. (2017) · ACS Nano · doi:10.1021/acsnano.6b07684 · Cited by 224 · see citing works
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Vasanawala, S. S., Nguyen, K., Hope, M. D., Bridges, M. D., Hope, T. A., Reeder, S. B., & Bashir, M. R. (2016) · Magnetic Resonance in Medicine · doi:10.1002/mrm.26151 · Cited by 210 · see citing works
Lunov, O., Syrovets, T., Büchele, B., Jiang, X., Röcker, C., Tron, K., Nienhaus, G. U., Walther, P., Mailänder, V., Landfester, K., et al. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.03.023 · Cited by 156 · see citing works
Demirer, G. S., Okur, A. C., & Kızılel, S. (2015) · Journal of Materials Chemistry B · doi:10.1039/c5tb00931f · Cited by 147 · see citing works
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Loomis, K. H., McNeeley, K. M., & Bellamkonda, R. V. (2010) · Soft Matter · doi:10.1039/c0sm00534g · Cited by 130 · see citing works
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Ghaghada, K. B., Ravoori, M. K., Sabapathy, D. G., Bankson, J. A., Kundra, V., & Annapragada, A. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007628 · Cited by 114 · see citing works
Ni, D., Zhang, J., Wang, J., Hu, P., Jin, Y., Tang, Z., Yao, Z., Bu, W., & Shi, J. (2017) · ACS Nano · doi:10.1021/acsnano.7b01297 · Cited by 107 · see citing works
Antonelli, A., Sfara, C., Manuali, E., Bruce, I. J., & Magnani, M. (2011) · Nanomedicine · doi:10.2217/nnm.10.163 · Cited by 86 · see citing works
Giannakou, C., Park, M. V. D. Z., de Jong, W., Loveren, H. V., Vandebriel, R. J., & Geertsma, R. E. (2016) · International Journal of Nanomedicine · doi:10.2147/ijn.s102385 · Cited by 79 · see citing works
Contemporary Imaging of Cerebral Arteriovenous Malformations
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de Rochefort, L., Nguyen, T. D., Brown, R., Spincemaille, P., Choi, G. H., Weinsaft, J. W., Prince, M. R., & Wang, Y. (2008) · Medical Physics · doi:10.1118/1.3002309 · Cited by 75 · see citing works
Xiao, W., Lin, J., Li, M., Ma, Y., Chen, Y., Zhang, C., Li, D., & Gu, H. (2012) · Contrast Media & Molecular Imaging · doi:10.1002/cmmi.501 · Cited by 69 · see citing works
MR Angiography of the Lower Extremities
Ersoy, H., & Rybicki, F. J. (2008) · American Journal of Roentgenology · doi:10.2214/ajr.07.2223 · Cited by 65 · see citing works
Nayak, A. B., Luhar, A., Hanudel, M. R., Gales, B., Hall, T. R., Finn, J. P., Salusky, I. B., & Zaritsky, J. J. (2014) · Pediatric Nephrology · doi:10.1007/s00467-014-2953-x · Cited by 62 · see citing works
A multiple gadolinium complex decorated fullerene as a highly sensitive T 1 contrast agent
Wang, L., Zhu, X., Tang, X., Wu, C., Zhou, Z., Sun, C., Deng, S., Ai, H., & Gao, J. (2015) · Chemical Communications · doi:10.1039/c5cc00285k · Cited by 63 · see citing works
Ferumoxytol as an off-label contrast agent in body 3T MR angiography: a pilot study in children
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Metz, S., Beer, A. J., Settles, M., Pelisek, J., Botnar, R. M., Rummeny, E. J., & Heider, P. (2010) · International journal of cardiac imaging · doi:10.1007/s10554-010-9736-7 · Cited by 43 · see citing works
Zhang, L., Zhong, X., Wang, L., Chen, H., Wang, Y. A., Yeh, J., Yang, L. P. H., & Mao, H. Z. (2010) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.22412 · Cited by 43 · see citing works
Klauser, A. S., Franz, M., Arora, R. R., Feuchtner, G. M., Gruber, J., Schirmer, M., Jaschke, W. R., & Gabl, M. (2010) · Arthritis Research & Therapy · doi:10.1186/ar3185 · Cited by 42 · see citing works
Rui, Y., Liang, B., Hu, F., Xu, J., Peng, Y., Yin, P., Duan, Y., Zhang, C., & Gu, H. (2016) · RSC Advances · doi:10.1039/c6ra00347h · Cited by 42 · see citing works
Jung, K., Kim, H., Lee, G. H., Kang, D.-S., Park, J. A., Kim, K. M., Chang, Y., & Kim, T. (2011) · Journal of Medicinal Chemistry · doi:10.1021/jm2002052 · Cited by 38 · see citing works
Stoumpos, S., Hennessy, M., Vesey, A. T., Radjenovic, A., Kasthuri, R. S., Kingsmore, D. B., Mark, P. B., & Roditi, G. (2017) · European Radiology · doi:10.1007/s00330-017-4934-5 · Cited by 38 · see citing works
Microwave-assisted synthesis of magnetite nanoparticles for MR blood pool contrast agents
Xiao, W., Gu, H., Li, D., Chen, D., Deng, X., Jiao, Z., & Lin, J. (2011) · Journal of Magnetism and Magnetic Materials · doi:10.1016/j.jmmm.2011.08.029 · Cited by 38 · see citing works
Xue, S., Qiao, J., Jiang, J., Hubbard, K., White, N. O., Wei, L., Li, S., Liu, Z., & Yang, J. J. (2014) · Medicinal Research Reviews · doi:10.1002/med.21313 · Cited by 37 · see citing works
Menke, J. (2009) · European Radiology · doi:10.1007/s00330-009-1403-9 · Cited by 37 · see citing works
Nguyen, K., Moriarty, J. M., Plotnik, A. N., Aksoy, O., Yoshida, T., Shemin, R. J., Suh, W., & Finn, J. P. (2017) · Radiology · doi:10.1148/radiol.2017162899 · Cited by 35 · see citing works
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Stoumpos, S., Hennessy, M., Vesey, A. T., Radjenovic, A., Kasthuri, R. S., Kingsmore, D. B., Mark, P. B., & Roditi, G. (2019) · European Radiology · doi:10.1007/s00330-019-06137-4 · Cited by 33 · see citing works
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Luhar, A., Khan, S. N., Finn, J. P., Ghahremani, S., Griggs, R., Zaritsky, J. J., Salusky, I. B., & Hall, T. R. (2016) · Pediatric Radiology · doi:10.1007/s00247-016-3605-z · Cited by 29 · see citing works
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Soloperto, G. (2012) · World Journal of Radiology · doi:10.4329/wjr.v4.i7.353 · Cited by 28 · see citing works
Imaging Modalities to Identity Inflammation in an Atherosclerotic Plaque
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Cheng, W., Ganesh, T., Martínez, F. M., Lam, J. W. Y., Yoon, H., Macgregor, R. B., Scholl, T. J., Cheng, H. M., & Zhang, X. (2014) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s00775-013-1073-6 · Cited by 27 · see citing works
Kos, S., Huegli, R. W., Hofmann, E., Quick, H. H., Kuehl, H., Aker, S., Kaiser, G. M., Borm, P. J. A., Jacob, A. L., & Bilecen, D. (2008) · CardioVascular and Interventional Radiology · doi:10.1007/s00270-008-9483-5 · Cited by 26 · see citing works
Self-citationHe, F., Zhu, L., Zhou, X., Zhang, P., Cheng, J., Qiao, Y., Feng, Y., Yue, S., Xu, M., Guan, J., et al. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c03530 · Cited by 26 · see citing works
Gd Complexes of DO3A-(Biphenyl-2,2′-bisamides) Conjugates as MRI Blood-Pool Contrast Agents
Jung, K., Kim, H., Park, J. A., Nam, K. S., Lee, G. H., Chang, Y., & Kim, T. (2012) · ACS Medicinal Chemistry Letters · doi:10.1021/ml300223b · Cited by 25 · see citing works
Suh, M., Park, J. Y., Ko, G. B., Kim, J. Y., Hwang, D. W., Rees, L., Conway, G. E., Doak, S. H., Kang, H., Lee, N., et al. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-02699-8 · Cited by 24 · see citing works
Wang, H., Jiang, Q., Shen, Y., Zhang, L., Haacke, E. M., Ge, Y., Qi, S., & Hu, J. (2020) · NMR in Biomedicine · doi:10.1002/nbm.4256 · Cited by 22 · see citing works
Kos, S., Huegli, R. W., Hofmann, E., Quick, H. H., Kuehl, H., Aker, S., Kaiser, G. M., Borm, P. J. A., Jacob, A. L., & Bilecen, D. (2009) · Minimally Invasive Therapy & Allied Technologies · doi:10.1080/13645700902921971 · Cited by 22 · see citing works
Self-citationBonlawar, J., Setia, A., Challa, R. R., Vallamkonda, B., Mehata, A. K., Vaishali, Viswanadh, M. K., & Muthu, M. S. (2024) · Nanotheranostics · doi:10.7150/ntno.95791 · Cited by 23 · see citing works
Huang, S. Y., Kim, C., Miller, M. J., Gupta, R. T., Lessne, M. L., Horvath, J. J., Boll, D. T., Evans, P. D., Befera, N. T., Krishnan, P., et al. (2013) · American Journal of Roentgenology · doi:10.2214/ajr.12.9611 · Cited by 21 · see citing works
Pulmonary MR Angiography Techniques and Applications
Hecht, E. M., & Rosenkrantz, A. B. (2009) · Magnetic Resonance Imaging Clinics of North America · doi:10.1016/j.mric.2009.01.001 · Cited by 21 · see citing works
Kim, H., Park, J. A., Kim, K. M., Sk, N., Kang, D.-S., Lee, J., Chang, Y., & Kim, T. (2010) · Chemical Communications · doi:10.1039/c0cc03145c · Cited by 20 · see citing works
Whole-Heart Coronary Magnetic Resonance Angiography at 1.5 Tesla
Wagner, M., Rösler, R., Lembcke, A. E., Butler, C., Dewey, M., Laule, M., Huppertz, A., Schwenke, C., Warmuth, C., Rief, M., et al. (2010) · Investigative Radiology · doi:10.1097/rli.0b013e3181fac6ef · Cited by 20 · see citing works
Röhrl, B., Kunz, R. P., Oberholzer, K., Pitton, M. B., Neufang, A., Dueber, C., & Kreitner, K. (2009) · European Radiology · doi:10.1007/s00330-009-1501-8 · Cited by 20 · see citing works
Camren, G. P., Wilson, G. J., Bamra, V. R., Nguyen, K. Q., Hippe, D. S., & Maki, J. H. (2014) · BioMed Research International · doi:10.1155/2014/625614 · Cited by 19 · see citing works
Kau, T., Gasser, J., Celedin, S., Rabitsch, E., Eicher, W., Uhl, E., & Hausegger, K. (2009) · American Journal of Neuroradiology · doi:10.3174/ajnr.a1622 · Cited by 19 · see citing works
Jaspers, K., Versluis, B., Leiner, T., Dijkstra, P., Oostendorp, M., van Golde, J. C., Post, M. J., & Backes, W. H. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016159 · Cited by 18 · see citing works
High relaxivity Gd3+-based organic nanoparticles for efficient magnetic resonance angiography
Liu, Z., Zhao, M., Wang, H., Fu, Z., Gao, H., Peng, W., Ni, D., Tang, W., & Gu, Y. (2022) · Journal of Nanobiotechnology · doi:10.1186/s12951-022-01363-3 · Cited by 18 · see citing works
Quantitative Imaging of Blood-Brain Barrier Permeability Following Repetitive Mild Head Impacts
Leaston, J., Qiao, J., Harding, I. C., Kulkarni, P., Gharagouzloo, C. A., Ebong, E. E., & Ferris, C. F. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.729464 · Cited by 17 · see citing works
Antonelli, A., Sfara, C., & Magnani, M. (2017) · Nano Research · doi:10.1007/s12274-016-1342-0 · Cited by 17 · see citing works
Trotier, A. J., Lefrançois, W., Renterghem, K. V., Franconi, J., Thiaudière, E., & Miraux, S. (2015) · Journal of Cardiovascular Magnetic Resonance · doi:10.1186/s12968-015-0167-4 · Cited by 15 · see citing works
Kos, S., Reisinger, C., Aschwanden, M., Bongartz, G. M., Jacob, A. L., & Bilecen, D. (2009) · American Journal of Roentgenology · doi:10.2214/ajr.08.1384 · Cited by 16 · see citing works
Self-citationRichardson, O., Bane, O., Scott, M. L. J., Tanner, S. F., Waterton, J. C., Sourbron, S. P., Carroll, T. J., & Buckley, D. L. (2014) · Magnetic Resonance in Medicine · doi:10.1002/mrm.25128 · Cited by 15 · see citing works
Beitzke, D., Wolf, F., Jülg, G., Lämmer, J., & Loewe, C. (2009) · CardioVascular and Interventional Radiology · doi:10.1007/s00270-009-9702-8 · Cited by 15 · see citing works
Wagner, M., Rief, M., Asbach, P., VOGTMANN, T., Huppertz, A., Beling, M., Butler, C., Laule, M., Warmuth, C., Taupitz, M., et al. (2009) · European Journal of Radiology · doi:10.1016/j.ejrad.2009.04.052 · Cited by 15 · see citing works
Mukai, K., Burris, N. S., Mahadevan, V. S., Foster, E., Ordovas, K. G., & Hope, M. D. (2017) · International journal of cardiac imaging · doi:10.1007/s10554-017-1224-x · Cited by 14 · see citing works
Contrast-Enhanced Magnetic Resonance Angiography
Peldschus, K., Hamdorf, M., Robert, P., Port, M., Graessner, J., Adam, G., & Herborn, C. U. (2008) · Investigative Radiology · doi:10.1097/rli.0b013e3181852158 · Cited by 14 · see citing works
A facile synthetic approach to a biodegradable polydisulfide MRI contrast agent
Cheng, W., Rajendran, R., Ren, W., Gu, L., Zhang, Y., Chuang, K., & Liu, Y. (2014) · Journal of Materials Chemistry B · doi:10.1039/c4tb00413b · Cited by 13 · see citing works
Extracardiac applications of MR blood pool contrast agent in children
Farmakis, S. G., & Khanna, G. (2014) · Pediatric Radiology · doi:10.1007/s00247-014-3167-x · Cited by 12 · see citing works
Liu, C., Liu, X., Wei, Z., Chang, Z., Bai, Y., Zeng, P., Cao, Q., Tie, C., Lei, Z., Sun, P., et al. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c16391 · Cited by 12 · see citing works
A High Relaxivity Magnetic Resonance Imaging Contrast Agent Targeted to Serum Albumin
Dumas, S., Troughton, J. S., Cloutier, N. J., Chasse, J. M., McMurry, T. J., & Caravan, P. D. (2008) · Australian Journal of Chemistry · doi:10.1071/ch08164 · Cited by 12 · see citing works
Use of blood pool agents with steady‐state MRI to assess the vascular system
Thakor, A. S., Chung, J., Patel, P. A., Chan, A., Ahmed, A. M., McNeil, G., Liu, D. M., Forster, B. B., & Klass, D. (2017) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.25636 · Cited by 12 · see citing works
Stanicki, D., Larbanoix, L., Boutry, S., Vangijzegem, T., Ternad, I., Garifo, S., Müller, R. N., & Laurent, S. (2021) · Journal of Materials Chemistry B · doi:10.1039/d1tb00573a · Cited by 12 · see citing works
Overcoming the low relaxivity of gadofosveset at high field with spin locking
Richardson, O., Scott, M. L. J., Tanner, S. F., Waterton, J. C., & Buckley, D. L. (2011) · Magnetic Resonance in Medicine · doi:10.1002/mrm.23316 · Cited by 11 · see citing works
Christie, A., Chandramohan, S., & Roditi, G. (2012) · Clinical Radiology · doi:10.1016/j.crad.2012.05.017 · Cited by 11 · see citing works
Mordasini, P., El‐Koussy, M., Schmidli, J., Bonél, H., Ith, M., Gralla, J., Schroth, G., & Hoppe, H. (2011) · European Journal of Radiology · doi:10.1016/j.ejrad.2011.02.025 · Cited by 11 · see citing works
Vascular Repair by Grafting Based on Magnetic Nanoparticles
Liu, X., Wang, N., Liu, X., Deng, R., Kang, R., & Xie, L. Y. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14071433 · Cited by 10 · see citing works
Galizia, M. S., Ward, E. V. M., Rodríguez, H. E., Collins, J. D., & Carr, J. (2013) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2012.09.018 · Cited by 10 · see citing works
Magnetic Core-Shell Nanoparticles for Biomedical Applications
Mandal, S., & Chaudhuri, K. (2017) · Springer eBooks · doi:10.1007/978-3-319-52087-2_12 · Cited by 10 · see citing works
Lim, R., Bruno, M. T., Rosenkrantz, A. B., Kim, D. C., Mulholland, T., Kwon, J., Palfrey, A., & Ogedegbe, O. (2014) · European Journal of Radiology · doi:10.1016/j.ejrad.2014.04.018 · Cited by 9 · see citing works
Pressacco, J., Papas, K., Lambert, J., Finn, J. P., Chauny, J., Desjardins, A., Irislimane, Y., Toporowicz, K., Lanthier, C., Samson, P., et al. (2019) · European Journal of Radiology · doi:10.1016/j.ejrad.2019.02.007 · Cited by 9 · see citing works
Gallo, C. J. R., Mammarappallil, J. G., Johnson, D. Y., Chalian, H., Ronald, J., Bashir, M. R., & Kim, C. (2020) · Radiology Cardiothoracic Imaging · doi:10.1148/ryct.2020200339 · Cited by 9 · see citing works
How Different Albumin-Binders Drive Probe Distribution of Fluorescent RGD Mimetics
Höltke, C., Alsibai, W., Grewer, M., Stölting, M., Geyer, C., Eisenblätter, M., Wildgruber, M., & Helfen, A. (2021) · Frontiers in Chemistry · doi:10.3389/fchem.2021.689850 · Cited by 9 · see citing works
Whole-body MR angiography in patients with peripheral arterial disease.
Nielsen, Y. W. (2010) · PubMed · Cited by 8 · see citing works
Synthesis and characterization of new low‐molecular‐weight lysine‐conjugated Gd‐DTPA contrast agents
Laurent, S., Burtéa, C., Elst, L. V., & Müller, R. N. (2010) · Contrast Media & Molecular Imaging · doi:10.1002/cmmi.422 · Cited by 8 · see citing works
Contrast-Enhanced Magnetic Resonance Angiography in Rabbits
Kinner, S., Maderwald, S., Parohl, N., Albert, J., Corot, C., Robert, P., Barkhausen, J., & VOGT, F. M. (2011) · Investigative Radiology · doi:10.1097/rli.0b013e31821ae21f · Cited by 8 · see citing works
Li, H., Luo, Q., Zhu, H., Li, Z., Wang, X., Roberts, N., Zhang, H., Gong, Q., Gu, Z., & Luo, K. (2020) · Polymer Chemistry · doi:10.1039/d0py01133a · Cited by 7 · see citing works
Ghanouni, P., Walters, S., & Vasanawala, S. S. (2011) · Pediatric Radiology · doi:10.1007/s00247-011-2254-5 · Cited by 5 · see citing works
Implementation of Nanoparticles in Cancer Therapy
Bayır, E., Bilgi, E., & Şendemir, A. (2014) · Advances in chemical and materials engineering book series · doi:10.4018/978-1-4666-5824-0.ch018 · Cited by 5 · see citing works
Welman, C. J., Harrison, C., & Low, R. S.-T. (2013) · Journal of Medical Imaging and Radiation Oncology · doi:10.1111/1754-9485.12027 · Cited by 5 · see citing works
Gadofosveset injection for magnetic resonance angiography
Chiribiri, A., Morton, G., & Nagel, E. C. (2010) · Imaging in Medicine · doi:10.2217/iim.10.39 · Cited by 4 · see citing works
von Tengg‐Kobligk, H., Mehndiratta, A., & Giesel, F. L. (2013) · Springer eBooks · doi:10.1007/978-1-84882-710-3_15 · Cited by 4 · see citing works
Peripheral MRA with k-space Segmentation and Blood-Pool Contrast Agent
Kinner, S., Zenge, M. O., Heilmaier, C., de Greiff, A., VOGT, F. M., Ladd, M. E., Barkhausen, J., & Quick, H. H. (2010) · Academic Radiology · doi:10.1016/j.acra.2010.08.009 · Cited by 3 · see citing works
Aguilar, Z. P. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-385089-8.00007-8 · Cited by 3 · see citing works
- Authors
- Bremerich, J., Bilecen, D., & Reimer, P.
- Affiliations
- University Hospital of Basel (CH)
- Städtisches Klinikum Karlsruhe (DE)
- Corresponding author
- Bremerich, Jens
- Venue
- European Radiology
- Published
- 2007-07-17
- Volume
- 17
- Issue
- 12
- Pages
- 3017-3024
- ISSN
- 0938-7994 (ISSN-L)
- 1432-1084
- OpenAlex
- W2032850755
- Cited by
- 139
- References
- 43
- Citations by year
- 2024: 5 · 2022: 5 · 2021: 6 · 2020: 7 · 2019: 4 · 2018: 2 · 2017: 11 · 2016: 14 · 2015: 5 · 2014: 16 · 2013: 7 · 2012: 7
- FWCI
- 1.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- European Radiology (publishedVersion)
- PubMed (publishedVersion)
- reroDoc Digital Library (submittedVersion)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Physical Sciences › Materials Science › Materials Chemistry › Lanthanide and Transition Metal Complexes
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
- Keywords
- blood pool contrast agent, contrast-enhanced MR angiography, gadofosveset, ultrasmall superparamagnetic iron oxide, gadolinium-based contrast agents, serum albumin binding, relaxivity, carotid angiography, renal angiography, peripheral angiography
- MeSH terms
- Contrast Media, Dextrans, Gadolinium, Humans, Iron, Organometallic Compounds, Oxides, Vascular Diseases, Magnetic Resonance Angiography, Ferrosoferric Oxide, Magnetite Nanoparticles
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