ChatGPT makes medicine easy to swallow: an exploratory case study on simplified radiology reports
Open accessAbstract
Objectives: To assess the quality of simplified radiology reports generated with the large language model (LLM) ChatGPT and to discuss challenges and chances of ChatGPT-like LLMs for medical text simplification. Methods: In this exploratory case study, a radiologist created three fictitious radiology reports which we simplified by prompting ChatGPT with “Explain this medical report to a child using simple language.” In a questionnaire, we tasked 15 radiologists to rate the quality of the simplified radiology reports with respect to their factual correctness, completeness, and potential harm for patients. We used Likert scale analysis and inductive free-text categorization to assess the quality of the simplified reports. Results: Most radiologists agreed that the simplified reports were factually correct, complete, and not potentially harmful to the patient. Nevertheless, instances of incorrect statements, missed relevant medical information, and potentially harmful passages were reported. Conclusion: While we see a need for further adaption to the medical field, the initial insights of this study indicate a tremendous potential in using LLMs like ChatGPT to improve patient-centered care in radiology and other medical domains. Clinical relevance statement: Patients have started to use ChatGPT to simplify and explain their medical reports, which is expected to affect patient-doctor interaction. This phenomenon raises several opportunities and challenges for clinical routine. Key Points: • Patients have started to use ChatGPT to simplify their medical reports, but their quality was unknown. • In a questionnaire, most participating radiologists overall asserted good quality to radiology reports simplified with ChatGPT. However, they also highlighted a notable presence of errors, potentially leading patients to draw harmful conclusions. • Large language models such as ChatGPT have vast potential to enhance patient-centered care in radiology and other medical domains. To realize this potential while minimizing harm, they need supervision by medical experts and adaption to the medical field. Graphical Abstract:
AI snapshot
Written from the paper’s full text.
TL;DR
In this exploratory case study, ChatGPT was prompted to simplify three fictitious radiology reports, and 15 radiologists generally rated the outputs as factually correct, complete, and not potentially harmful. However, they also identified incorrect statements, missing relevant information, and potentially harmful passages in a considerable number of simplified reports.
Key findings
- Across all 45 simplified reports, median ratings were 2 (“Agree”) for factual correctness and completeness, and 4 (“Disagree”) for potential harm; no radiologist selected “Strongly disagree” for correctness/completeness, and none selected “Strongly agree” for potential harm.
- Free-text review found incorrect text passages in 23/45 simplified reports (51%), missing relevant medical information in 10/45 (22%), and potentially harmful conclusions in 16/45 (36%).
- Error categories included misinterpretation of medical terms (e.g., “DD”/differential diagnosis mistaken as final diagnosis; “thyroid struma” described as “infection in their thyroid gland” or “extra thyroid gland”), hallucinations (e.g., “no signs of cancer in the thyroid gland”; “brain does not seem to be damaged”), imprecise language, odd language, unmentioned findings, and unspecific location information.
- The Oncol. CT report had the highest mean factual-correctness rating (2.5, SD 1.1) and potential-harm mean 3.3 (SD 1.1); Head MRI had a slightly lower potential-harm median (3) than Knee MRI and Oncol. CT (both median 4).
Methods
- Prospective exploratory case study using three fictitious radiology reports (Knee MRI, Head MRI, Oncol. CT) written by a radiologist with 10 years of experience and intended to be of intermediate complexity.
- The ChatGPT online interface (version December 15th, 2022) was prompted with “Explain this medical report to a child using simple language:” followed by the original report; the model was restarted and prompted 15 times per report, generating 45 simplified reports.
- Fifteen radiologists with median experience of 5 years (IQR [1–10]) rated one randomly selected simplified version per original report on 5-point Likert scales for factual correctness, completeness, and potential harm, with free-text follow-up; analysis used descriptive statistics and inductive categorization.
Limitations
- Stated: small number of original reports (n = 3) and experts (n = 15); fictitious reports were written to represent intermediate medical complexity and translated to English by a non-native-speaking radiologist; only one prompt phrasing was used after heuristic selection; the study did not measure the quality of simplification.
- Evident: the radiologist sample came from a single clinic (“from our clinic”), and ChatGPT outputs were non-deterministic, while each questionnaire included only one randomly selected simplified version per original report.
- Evident: the study used fictitious reports and no patient information, so it does not validate performance on real clinical reports or patient outcomes.
Model-written summary. Check it against the paper before relying on it.
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Claims the paper makes
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- Findingown data
The abbreviation "DD" (differential diagnosis) was often mistaken as a final diagnosis in the simplified reports.
“The abbreviation “DD” (differential diagnosis) was often mistaken as a final diagnosis (B.2.6, B.2.8)”
Quote in the paperNot a substantial claim - Findingown data
Most participating radiologists agreed that the simplified radiology reports were factually correct (median rating 2 on a 5-point scale where 1=strongly agree).
“Most radiologists agreed that the simplified reports were factually correct, complete, and not potentially harmful to the patient.”
- Also stated in: § Likert scale analysis · plain
“The participants generally agreed (median = 2) with the statements that the simplified reports are factually correct and complete, respectively.”
Quote in the paperSubstantial claim - Also stated in: § Likert scale analysis · plain
- Findingown data
Misinterpretation of differential diagnosis ("DD") as final diagnosis was considered potentially harmful for the patient.
“For instance, the misinterpretation of differential diagnosis (“DD”) as final diagnosis was considered potentially harmful for the patient, e.g., one radiologist commented: “GBM is one (likely) DD which implies that other DDs exist (e.g. radionecrosis).” (B.2.7).”
Quote in the paperSubstantial claim - Findingown data
For potential harm, the Head MRI report had a slightly lower median rating (median = 3) than the Knee MRI and Oncol. CT reports (median = 4).
“For potential harm, the Head MRI report had a slightly lower median (median = 3) compared to the other two reports (median = 4).”
Quote in the paperNot a substantial claim - Findingown data
Most participating radiologists agreed that the simplified radiology reports were complete (median rating 2).
“Most radiologists agreed that the simplified reports were factually correct, complete, and not potentially harmful to the patient.”
- Also stated in: § Likert scale analysis · plain
“The participants generally agreed (median = 2) with the statements that the simplified reports are factually correct and complete, respectively.”
Quote in the paperSubstantial claim - Also stated in: § Likert scale analysis · plain
- Findingown data
The simplified reports contained unsuited and odd language, e.g., the idiom "wear and tear" to describe tendon degeneration and "to see how the cancer is doing" for a radiological examination.
“Additionally, we found instances of unsuited and odd language. The idiom “wear and tear” (B.1.4) was used to describe the degeneration of tendons and a radiological examination was circumscribed as “to see how the cancer is doing” (B.3.8).”
Quote in the paperNot a substantial claim - Findingown data
Some findings in the simplified reports were made up by ChatGPT (hallucinations), e.g., "no signs of cancer in the thyroid gland" or "brain does not seem to be damaged".
“Some findings in the simplified reports were made up by ChatGPT. Examples for these hallucinations were “no signs of cancer in the thyroid gland” (B.3.3) or “brain does not seem to be damaged” (B.2.9).”
Quote in the paperSubstantial claim - Findingown data
Most participating radiologists disagreed that the simplified reports would lead patients to draw wrong conclusions resulting in physical and/or psychological harm (median rating 4).
“In line with the findings for factual correctness and completeness, the participants disagreed (median = 4) on the potential of wrong conclusions drawn from the simplified reports resulting in physical and/or psychological harm.”
- Also stated in: § Likert scale analysis · plain
“No radiologist chose “Strongly agree.””
Quote in the paperSubstantial claim - Also stated in: § Likert scale analysis · plain
- Findingown data
Participants highlighted incorrect text passages in 23 simplified reports (51%).
“Participants highlighted incorrect text passages in 23 simplified reports (51%), listed missing relevant information for 10 simplified reports (22%), and listed potentially harmful conclusions for 16 simplified reports (36%).”
Quote in the paperSubstantial claim - Findingown data
Participants listed potentially harmful conclusions for 16 simplified reports (36%).
“Participants highlighted incorrect text passages in 23 simplified reports (51%), listed missing relevant information for 10 simplified reports (22%), and listed potentially harmful conclusions for 16 simplified reports (36%).”
- Also stated in: § Discussion · hedged
“In about one-third of all simplified reports, participating radiologists found errors, which might lead patients to draw wrong conclusions, potentially resulting in physical and/or psychological harm.”
Quote in the paperSubstantial claim - Also stated in: § Discussion · hedged
- Findingown data
The simplified reports contained imprecise language, e.g., describing the medial compartment of the knee as the "middle part of your leg" or the brain as the "head".
“In some cases, we observed passages of imprecise language. For instance, the medial compartment of the knee was described as the “middle part of your leg” (B.1.5), or the brain as the “head” (B.2.7).”
Quote in the paperNot a substantial claim - Findingown data
Missing or unspecific location information was observed, e.g., imprecise localization resulted in ambiguous assignment of a growing mass to present or excised tumor (B.2.11).
“Additionally, we observed missing or unspecific location information, e.g., imprecise localization resulted in ambiguous assignment of a growing mass to present or excised tumor (B.2.11).”
Quote in the paperNot a substantial claim - Findingown data
Participants listed missing relevant information for 10 simplified reports (22%).
“Participants highlighted incorrect text passages in 23 simplified reports (51%), listed missing relevant information for 10 simplified reports (22%), and listed potentially harmful conclusions for 16 simplified reports (36%).”
Quote in the paperNot a substantial claim - Findingown data
A growing mass of "currently max. 22 mm" was incorrectly simplified as a "small, abnormal growth that has gotten bigger".
“In addition, a growing mass of “currently max. 22 mm” was incorrectly simplified as a “small, abnormal growth that has gotten bigger” (B.2.3).”
Quote in the paperNot a substantial claim - Findingown data
The fact that the solid portions of the pulmonary metastases are decreasing-consistent with therapy response-was not included in simplified report B.3.5.
“The fact that the solid portions of the pulmonary metastases are decreasing—consistent with therapy response—was not included in the simplified report B.3.5.”
Quote in the paperNot a substantial claim - Interpretationown data
The identified incorrect text passages and missing relevant medical information could lead patients to draw harmful conclusions.
“Nevertheless, instances of incorrect text passages and missing relevant medical information were identified in a considerable number of cases, which could lead patients to draw harmful conclusions.”
Quote in the paperSubstantial claim - Interpretationown data
ChatGPT is in principle able to simplify radiology reports.
“In this exploratory study, most participating radiologists agreed that the simplified reports were factually correct, complete, and not potentially harmful to the patient, indicating that ChatGPT is in principle able to simplify radiology reports.”
Quote in the paperSubstantial claim - Study design and conductown data
The number of original radiology reports (n = 3) and experts (n = 15) for assessing the quality of the simplified reports is small.
“The number of original radiology reports (n = 3) and experts (n = 15) for assessing the quality of the simplified reports is small.”
Quote in the paperSubstantial claim - Interpretationreasoning
These model-related challenges discourage the use of ChatGPT for the task of simplification of radiology reports in an autonomous setting.
“In summary, these model-related challenges discourage the use of ChatGPT for the task of simplification of radiology reports in an autonomous setting.”
Quote in the paperSubstantial claim- Rests on an assumption: The training data of ChatGPT is static, i.e., new research findings are not considered in ChatGPT’s output.
- Rests on an assumption: Uploading protected health information to a proprietary service such as ChatGPT might compromise patients’ privacy.
- Premisecitation
For patients without a medical background, radiology reports are often inaccessible.
“For patients without a medical background, these reports are often inaccessible [9–12].”
Quote in the paperSubstantial claim0 of 4 sources checked- cites [9] Keselman A, Slaughter L, Arnott-Smith C et al (2007) Towards consumer-friendly PHRs: patients’ experience with reviewing their health records. In: AMIA Annual Symposium Proceedings. American Medical Informatics Association, p 399
Not checked in the free run.
- cites [10] Yi PH, Golden SK, Harringa JB, Kliewer MA (2019) Readability of lumbar spine MRI reports: will patients understand? AJR Am J Roentgenol 212(3):602–606 source
Not checked in the free run.
- cites [11] Kindig DA, Panzer AM, Nielsen-Bohlman L, editors (2004) Health literacy: a prescription to end confusion. National Academies Press, Washington, DC source
Not checked in the free run.
- cites [12] Martin-Carreras T, Cook TS, Kahn CE (2019) Readability of radiology reports: implications for patient-centered care. Clin Imaging 54:116–120 source
Not checked in the free run.
- Premisecitation
Most authors focused on summarization of radiology reports, i.e., on the creation of a shorter version that includes all important aspects at the same level of text complexity.
“So far, most authors focused on summarization of radiology reports, i.e., on the creation of a shorter version that includes all important aspects at the same level of text complexity [23–26].”
Quote in the paperNot a substantial claim0 of 4 sources checked- cites [23] Zhang Y, Ding DY, Qian T, Manning CD, Langlotz CP (2018) Learning to summarize radiology findings. In: Proceedings of the Ninth International Workshop on Health Text Mining and Information Analysis, Louhi@EMNLP. Association for Computational Linguistics, p 204–213 source
Not checked in the free run.
- cites [24] Cai X, Liu S, Han J, Yang L, Liu Z, Liu T (2021) ChestXRayBERT: a pretrained language model for chest radiology report summarization. IEEE Trans Multimed 25:845–855 source
Not checked in the free run.
- cites [25] Liang S, Kades K, Fink M et al (2022) Fine-tuning BERT models for summarizing german radiology findings. In: Proceedings of the 4th Clinical Natural Language Processing Workshop, p 30–40 source
Not checked in the free run.
- cites [26] Chaves A, Kesiku C, Garcia-Zapirain B (2022) Automatic text summarization of biomedical text data: a systematic review. Information 13(8):393 source
Not checked in the free run.
- Classified as probably not a substantial claim. 17
- May combine two claims. 15
Probably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataThe incorrect text passages were categorized into misinterpretation of medical terms, hallucinations, imprecise language, and odd language.
“In the case of incorrect text passages, we identified the inductive categories misinterpretation of medical terms, hallucinations, imprecise language, and odd language.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataPotentially harmful unmentioned findings were found, e.g., the sentence "the parts that are staying the same size are changing" was found to be an unclear statement missing interpretation.
“We also found potentially harmful unmentioned findings in the simplified report. The sentence “the parts that are staying the same size are changing” (B.3.5) was found to be an unclear statement missing interpretation.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataIn all cases, ChatGPT generated plausible-sounding outputs and did not indicate that the response could be incorrect.
“Even though the model is able to state to not know the answer [1], in all cases ChatGPT generated plausible-sounding outputs, while it did not indicate that the response could be incorrect.”
Quote in the paperSubstantial claimMay combine two claims.
FindingreasoningChatGPT's output is non-deterministic, i.e., applying the same prompt multiple times results in different responses, hindering reproducibility.
“Furthermore, ChatGPT’s output is non-deterministic, i.e., applying the same prompt multiple times results in different responses, hindering reproducibility.”
- Also stated in: § Simplification of radiology reports using ChatGPT · plain
“The version of the interface of ChatGPT used in this study does not allow changing any model settings, resulting in non-deterministic outputs.”
Quote in the paperSubstantial claim- Also stated in: § Simplification of radiology reports using ChatGPT · plain
May combine two claims.
Findingown dataParticipants rated the hallucination "brain does not seem to be damaged" as potentially harmful to the patient, as the original report describes a growing mass.
“For the category of hallucinations, participants rated the passage “brain does not seem to be damaged” (B.2.9) as potentially harmful to the patient, as the original report describes a growing mass.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
Findingown dataThe wording "small growth" was deemed a harmful conclusion because the original report states progression in size, which "almost doubled".
“Furthermore, the wording “small growth” (B.2.3) was deemed a harmful conclusion, as the original report (B.2.0) states a progression in size, which “almost doubled.””
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataChatGPT described "thyroid struma" as "infection in their thyroid gland" in one instance and as "extra thyroid gland" in another.
“Furthermore, “thyroid struma” was described by ChatGPT in one instance as “infection in their thyroid gland” (B.3.13) and in another as “extra thyroid gland” (B.3.7).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataMissing relevant medical information was categorized into unmentioned findings and unspecific location.
“Missing relevant medical information was categorized into unmentioned findings and unspecific location.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataImprecise language highlighted as incorrect was sometimes also graded as potentially harmful to the patient, e.g., "not clear that spots are pulmonal metastases" and "some extra fluid" is not a significant increasing edema.
“Additionally, we observed that imprecise language highlighted as incorrect was sometimes also graded as potentially harmful to the patient. For example, participants listed that it is “not clear that spots are pulmonal metastases” (B.3.5) and that “some extra fluid” is not a significant increasing edema (B.2.13).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataLymph nodes were simplified as "they might have cancer" although the original report stated "no evidence of recurrence or new lymph node metastases".
“Lymph nodes were simplified as “they might have cancer” (B.3.9), but the original report stated that there was “no evidence of recurrence or new lymph node metastases.””
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataGrammatical errors such as "CT scan" instead of "CT scanner" were the exception.
“Grammatical errors such as “CT scan” instead of “CT scanner” (B.3.7) were the exception.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenWritten informed consent was obtained from participating radiologists.
“Written informed consent was obtained from participating radiologists.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductnone givenThe fictitious original reports were written to represent an intermediate level of medical complexity and translated to English by a non-native-speaking radiologist.
“The fictitious original reports were written to represent an intermediate level of medical complexity and translated to English by a non-native-speaking radiologist.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
PremisecitationThere is a huge need for text simplification in the medical domain.
“In the medical domain, there is a huge need for text simplification [8, 9].”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [8] Barrett SK, Patrie J, Kitts AB, Hanley M, Swanson CM (2021) Vitzthum von Eckstaedt H, et al Patient-centered reporting in radiology: a single-site survey study of lung cancer screening results. J Thorac Imaging 36(6):367 source
Not checked in the free run.
- cites [9] Keselman A, Slaughter L, Arnott-Smith C et al (2007) Towards consumer-friendly PHRs: patients’ experience with reviewing their health records. In: AMIA Annual Symposium Proceedings. American Medical Informatics Association, p 399
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductreasoningAccording to the rules of the Ethics Committee of the Faculty of Medicine, LMU Munich, no ethical consultation was necessary for the approval of this study.
“According to the rules of the Ethics Committee of the Faculty of Medicine, LMU Munich, no ethical consultation was therefore necessary for the approval of this study.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationLLMs like ChatGPT have intrinsic biases, including stereotypical associations, negative sentiment towards specific groups, and biases due to imbalanced training data.
“Also, it is well established that LLMs like ChatGPT have intrinsic biases, including stereotypical associations, or negative sentiment towards specific groups, as well as biases due to imbalanced training data [6, 34, 35].”
Quote in the paperSubstantial claim0 of 3 sources checked- cites [6] Brown T, Mann B, Ryder N, Subbiah M, Kaplan JD, Dhariwal P et al (2020) Language models are few-shot learners. Adv Neural Inf Process Syst 33:1877–1901
Not checked in the free run.
- cites [34] Bender EM, Gebru T, McMillan-Major A, Shmitchell S (2021) On the dangers of stochastic parrots: can language models be too big?. In: Proceedings of the 2021 ACM Conference on Fairness, Accountability, and Transparency. Association for Computing Machinery, New York, p 610–623 source
Not checked in the free run.
- cites [35] Bommasani R, Hudson DA, Adeli E et al (2021) On the opportunities and risks of foundation models. ArXiv Prepr ArXiv210807258.
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataThe radiologists' answers were collected in anonymized questionnaires.
“Their answers were collected in anonymized questionnaires.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable), S4 (based). May combine two claims.
InterpretationreasoningSimplified and thus more comprehensible reports would enable patients to better understand and oversee their own health situation and empower them to make informed and active decisions throughout the medical treatment process.
“Simplified and thus more comprehensible reports would enable patients to better understand and oversee their own health situation and empower them to make informed and active decisions throughout the medical treatment process.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductnone givenWe used only one phrasing of the prompt for report simplification after a heuristic selection process and did not measure the quality of simplification.
“We used only one phrasing of the prompt for report simplification after a heuristic selection process and did not measure the quality of simplification.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationRadiological findings might have immediate consequences for patients, but they are typically only communicated in a free-text report in specialized medical jargon, targeting a clinician or doctor as the recipient.
“Radiological findings might have immediate consequences for patients. However, they are typically only communicated in a free-text report in specialized medical jargon, targeting a clinician or doctor as the recipient.”
Quote in the paperSubstantial claim0 of 4 sources checked- cites [9] Keselman A, Slaughter L, Arnott-Smith C et al (2007) Towards consumer-friendly PHRs: patients’ experience with reviewing their health records. In: AMIA Annual Symposium Proceedings. American Medical Informatics Association, p 399
Not checked in the free run.
- cites [10] Yi PH, Golden SK, Harringa JB, Kliewer MA (2019) Readability of lumbar spine MRI reports: will patients understand? AJR Am J Roentgenol 212(3):602–606 source
Not checked in the free run.
- cites [11] Kindig DA, Panzer AM, Nielsen-Bohlman L, editors (2004) Health literacy: a prescription to end confusion. National Academies Press, Washington, DC source
Not checked in the free run.
- cites [12] Martin-Carreras T, Cook TS, Kahn CE (2019) Readability of radiology reports: implications for patient-centered care. Clin Imaging 54:116–120 source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
InterpretationreasoningThese errors can be grouped into the same error categories that were found for factual correctness and completeness.
“These errors can be grouped into the same error categories that were found for factual correctness and completeness.”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationreasoningMisinterpretation of medical terms hinting at recurrence of cancer or understating progression of a disease is likely to cause harm for patients.
“For example, misinterpretation of medical terms hinting at recurrence of cancer or understating progression of a disease is likely to cause harm for patients.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim. May combine two claims.
PremisecitationChatGPT can generate plausible-sounding text, but the content does not need to be true.
“As known for other LLMs [13, 14], ChatGPT can generate plausible-sounding text, but the content does not need to be true (Fig. 1).”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [13] Lin S, Hilton J, Evans O (2022) TruthfulQA: measuring how models mimic human falsehoods. In: Proceedings of the 60th Annual Meeting of the Association for Computational Linguistics, ACL. Association for Computational Linguistics, p 3214–52 source
Not checked in the free run.
- cites [14] Taylor R, Kardas M, Cucurull G et al (2022) Galactica: a large language model for science. ArXiv Prepr ArXiv221109085.
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationEfforts to adapt LLMs to the medical field have been made, e.g., by Lee et al, Gu et al, and Singhal et al.
“Efforts in this direction have been made, e.g., by Lee et al, Gu et al, and Singhal et al [20–22].”
Quote in the paperNot a substantial claim0 of 3 sources checked- cites [20] Lee J, Yoon W, Kim S et al (2020) BioBERT: a pre-trained biomedical language representation model for biomedical text mining. Bioinformatics 36(4):1234–1240 source
Not checked in the free run.
- cites [21] Gu Y, Tinn R, Cheng H et al (2021) Domain-specific language model pretraining for biomedical natural language processing. ACM Trans Comput Healthc. 3(1):2:1–2:23 source
Not checked in the free run.
- cites [22] Singhal K, Azizi S, Tu T et al (2022) Large language models encode clinical knowledge [Internet]. arXiv; [cited 2023 Jan 13].
Not checked in the free run.
May combine two claims.
PremisecitationPrevious approaches for the simplification of radiology reports mostly replaced recurrent phrases or augmented radiology reports with lay-language definitions.
“Previous approaches for the simplification of radiology reports mostly replaced recurrent phrases [29–32] or augmented radiology reports with lay-language definitions [33].”
Quote in the paperNot a substantial claim0 of 5 sources checked- cites [29] Kvist M, Velupillai S (2013) Professional language in Swedish radiology reports–characterization for patient-adapted text simplification. In: Scandinavian Conference on Health Informatics. Linköping University Electronic Press, p 55–59
Not checked in the free run.
- cites [30] Abrahamsson E, Forni T, Skeppstedt M, Kvist M (2014) Medical text simplification using synonym replacement: adapting assessment of word difficulty to a compounding language. In: Proceedings of the 3rd Workshop on Predicting and Improving Text Readability for Target Reader Populations (PITR). p 57–65 source
Not checked in the free run.
- cites [31] Ramadier L, Lafourcade M (2017) Radiological text simplification using a general knowledge base. In: International Conference on Computational Linguistics and Intelligent Text Processing. Springer, p 617–627 source
Not checked in the free run.
- cites [32] Qenam B, Kim TY, Carroll MJ, Hogarth M (2017) Text simplification using consumer health vocabulary to generate patient-centered radiology reporting: translation and evaluation. J Med Internet Res 19(12):e417 source
Not checked in the free run.
- cites [33] Oh SC, Cook TS, Kahn CE (2016) PORTER: a prototype system for patient-oriented radiology reporting. J Digit Imaging 29(4):450–454 source
Not checked in the free run.
Probably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing), S4 (based).
InterpretationreasoningThe remaining inductive categories might be attributed to the fact that ChatGPT was trained on general data and not tuned to the task of radiology report simplification.
“The remaining inductive categories might be attributed to the fact that ChatGPT was trained on general data and not tuned to the task of radiology report simplification.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing).
PremisecitationHallucinations are difficult to remedy.
“Hallucinations are an intrinsic problem of generative models like LLMs [15] and difficult to remedy [16, 17].”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [16] Wang C, Sennrich R (2020) On exposure bias, hallucination and domain shift in neural machine translation. In: Proceedings of the 58th Annual Meeting of the Association for Computational Linguistics [Internet]. Online: Association for Computational Linguistics; [cited 2023 Jan 24]. p 3544–52 source
Not checked in the free run.
- cites [17] Guerreiro NM, Voita E, Martins AFT (2022) Looking for a needle in a haystack: a comprehensive study of hallucinations in neural machine translation [Internet]. arXiv; [cited 2023 Jan 24]. source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationHallucinations are an intrinsic problem of generative models like LLMs.
“Hallucinations are an intrinsic problem of generative models like LLMs [15] and difficult to remedy [16, 17].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [15] Zhou C, Neubig G, Gu J et al (2021) Detecting hallucinated content in conditional neural sequence generation. In: Findings of the association for computational linguistics: ACL/IJCNLP. Association for Computational Linguistics, p 1393–404 source
Not checked in the free run.
The paper relies on this without support.
Patients have started to use ChatGPT to simplify and explain their medical reports.
“Patients have started to use ChatGPT to simplify and explain their medical reports, which is expected to affect patient-doctor interaction.”
The paper relies on this without support.
ChatGPT was not explicitly trained for medical text simplification and is not intended to be used for this critical task.
“At the same time, ChatGPT was not explicitly trained for medical text simplification and is not intended to be used for this critical task.”
The paper relies on this without support.
The training data of ChatGPT is static, i.e., new research findings are not considered in ChatGPT’s output.
“The training data is static, i.e., new research findings are not considered in ChatGPT’s output.”
The paper relies on this without support.
The resulting models lack the accessibility and quality of ChatGPT.
“However, the resulting models lack the accessibility and quality of ChatGPT.”
The paper relies on this without support.
Uploading protected health information to a proprietary service such as ChatGPT might compromise patients’ privacy.
“Finally, uploading protected health information to a proprietary service, such as ChatGPT, might compromise patients’ privacy.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
ChatGPT has great potential to become a daily assistant for purposes of general or professional consulting.
“Both versions are popular and remarkably successful so that ChatGPT has great potential to become a daily assistant for purposes of general or professional consulting (Jeblick et al., 2023).”
From Teachers vs. Chat GPT: identifying and naming acts of online sexual abuse (2025) · cites this paper as Jeblick et al., 2023
The Introduction describes ChatGPT’s growing public popularity, and the Discussion sees great potential for it to help patients understand radiology reports. But the paper does not establish that both versions are successful or that ChatGPT is suited to be a daily assistant for general or professional consulting. Its proposed clinical use requires a medically adapted model and radiologist review. (LLM, conf=0.88)
Experimental — accuracy not yet measuredThe ability of ChatGPT to help streamline the clinical workflow appears promising, with possible cost savings and increased efficiency in health care delivery.
“The ability of ChatGPT to help in streamlining the clinical workflow appears promising, with possible cost savings and increased efficiency in health care delivery [31,37,39,77].”
From ChatGPT Utility in Healthcare Education, Research, and Practice: Systematic Review on the Promising Perspectives and Valid Concerns (2023) · cites this paper as [77]
The Discussion envisages integrating ChatGPT-like tools into radiology centers to generate simplified reports automatically, subject to radiologist review. This supports a possible role in clinical workflow, but the paper does not establish or predict cost savings or increased efficiency in health care delivery. The indexed passages do not provide page numbers. (LLM, conf=0.82)
Experimental — accuracy not yet measuredEthical issues including risk of bias and transparency issues appeared as recurring major concerns in health care settings.
“Ethical issues including the risk of bias and transparency issues appeared as recurring major concerns [51,68,69,77].”
From ChatGPT Utility in Healthcare Education, Research, and Practice: Systematic Review on the Promising Perspectives and Valid Concerns (2023) · cites this paper as [77]
The Discussion (page not available in our copy) identifies intrinsic bias in ChatGPT and describes potentially harmful errors as a medical-ethics concern. It does not identify transparency as a concern or establish that these issues recur across healthcare settings. (LLM, conf=0.85)
Experimental — accuracy not yet measuredChatGPT hallucination could be risky if the generated content is not thoroughly evaluated by researchers and health providers with proper expertise.
“Importantly, the concept of ChatGPT hallucination could be risky if the generated content is not thoroughly evaluated by researchers and health providers with proper expertise [37,56,73,77,79].”
From ChatGPT Utility in Healthcare Education, Research, and Practice: Systematic Review on the Promising Perspectives and Valid Concerns (2023) · cites this paper as [77]
ChatGPT plays a crucial role in pandemic management by aiding in the swift and accurate dissemination of critical information.
“ChatGPT plays a crucial role in pandemic management by aiding in the swift and accurate dissemination of critical information.”
ChatGPT's natural language processing capabilities enable it to generate coherent responses, making it a valuable tool for healthcare organisations.
“Its natural language processing capabilities enable it to generate coherent responses, making it a valuable tool for healthcare organisations.”
ChatGPT provides rapid updates, preventive measures, and medical guidelines to the public during health crises.
“Specific advantages include its ability to provide rapid updates, preventive measures, and medical guidelines to the public.”
ChatGPT can function as a virtual assistant, offering patients crucial preoperative information for cosmetic orthognathic surgery.
“Within the realm of surgical procedures, such as cosmetic orthognathic surgery, ChatGPT can function as a virtual assistant, offering patients crucial preoperative information.”
ChatGPT can offer standardised and accurate responses that prepare patients for consultations and help them make informed decisions.
“ChatGPT can offer standardised and accurate responses, which prepare patients for their consultations and help them make informed decisions [5,6,7,8,9,10,42,43].”
ChatGPT can be used in pandemic management, surgical consultations, dental practices, medical education, disease diagnosis, cellular imaging, sonar imaging, radiology, and pharmaceutical research.
“It was used in all areas: healthcare and management [5,6,7,8,9], aiding cosmetic orthognathic surgery consultation [10], revolutionising dental practices [8,11,12], medical scientific articles and education fields [6,9,13,14,15,16,17,18,19,20,21,22,23], support in disease diagnosis [24], revolutionising radiology, sonar imaging and writing assessment [13,25,26,27,28,29,30,31,32,33], pharmaceutical”
GPT-3.5 iteration has already shown promise in several routine medical tasks and medical research.
“ChatGPT’s GPT-3.5 iteration has already shown promise in several routine medical tasks and medical research [4-7], even raising ethical concerns in the literature [2,3,8].”
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Using AI-generated suggestions from ChatGPT to optimize clinical decision support
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Large Language Models in Medicine: The Potentials and Pitfalls
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Gender bias and stereotypes in Large Language Models
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“Responsible Generative AI Previous works have discussed the ethical implications or concerns associated with ChatGPT (and other LLMs) (Jabotinsky and Sarel, 2022; Susnjak, 2022; Blanco-Gonzalez et al., 2022; Aydın and Karaarslan, 2022; Jeblick et al., 2022).”
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Domain Specialization as the Key to Make Large Language Models Disruptive: A Comprehensive Survey
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Exploring ChatGPT Capabilities and Limitations: A Survey
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Using ChatGPT in Medical Research: Current Status and Future Directions
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The risks of using ChatGPT to obtain common safety-related information and advice
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ChatGPT: promise and challenges for deployment in low- and middle-income countries
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How Secure is Code Generated by ChatGPT?
Khoury, R., Avila, A. R., Brunelle, J., & Camara, B. M. (2023) · 2023 IEEE International Conference on Systems, Man, and Cybernetics (SMC) · doi:10.1109/smc53992.2023.10394237 · Cited by 141 · see citing works
Large language models for structured reporting in radiology: past, present, and future
Busch, F., Hoffmann, L., dos Santos, D. P., Makowski, M. R., Saba, L., Prucker, P., Hadamitzky, M., Navab, N., Kather, J. N., Truhn, D., et al. (2024) · European Radiology · doi:10.1007/s00330-024-11107-6 · Cited by 134 · see citing works
ChatGPT in radiology: A systematic review of performance, pitfalls, and future perspectives
Keshavarz, P., Bagherieh, S., Nabipoorashrafi, S. A., Chalian, H., Rahsepar, A. A., Kim, G. H. J., Hassani, C., Raman, S. S., & Bedayat, A. (2024) · Diagnostic and Interventional Imaging · doi:10.1016/j.diii.2024.04.003 · Cited by 132 · see citing works
Quality of Large Language Model Responses to Radiation Oncology Patient Care Questions
Yalamanchili, A., Sengupta, B., Song, J., Lim, S. N., Thomas, T. O., Mittal, B. B., Abazeed, M. E., & Teo, P. T. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.4630 · Cited by 128 · see citing works
Ayre, J., Mac, O., McCaffery, K., McKay, B. R., Liu, M., Shi, Y., Rezwan, A., & Dunn, A. G. (2024) · Journal of General Internal Medicine · doi:10.1007/s11606-023-08469-w · Cited by 124 · see citing works
Is ChatGPT accurate and reliable in answering questions regarding head and neck cancer?
Kuşçu, O., Pamuk, E., Süslü, N., & Hosal, S. A. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1256459 · Cited by 124 · see citing works
ICT students' perceptions towards ChatGPT: An experimental reflective lab analysis
Elkhodr, M., Gide, E., Wu, M., & Darwish, O. (2023) · STEM Education · doi:10.3934/steme.2023006 · Cited by 117 · see citing works
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- Authors
- Jeblick, K., Schachtner, B., Dexl, J., Mittermeier, A., Stüber, A. T., Topalis, J., Weber, T., Wesp, P., Sabel, B. O., Ricke, J., & Ingrisch, M.
- Affiliations
- LMU Klinikum (DE)
- Corresponding author
- Jeblick, Katharina
- ORCID
- Venue
- European Radiology
- Published
- 2023-10-05
- Volume
- 34
- Issue
- 5
- Pages
- 2817-2825
- ISSN
- 0938-7994 (ISSN-L)
- 1432-1084
- PMC
- PMC11126432
- OpenAlex
- W4387356888
- Cited by
- 549
- References
- 22
- Citations by year
- 2026: 105 · 2025: 152 · 2024: 157 · 2023: 133 · 2022: 1
- FWCI
- 21.84
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- European Radiology (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Open access LMU (Ludwid Maxmilian's Universitat Munchen) (submittedVersion, cc-by)
- PUBLISSO (German National Library of Medicine) (submittedVersion, cc-by)
- Funders
- Deutsche Forschungsgemeinschaft (460037581)
- Universitätsklinik München
- Topics
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Physical Sciences › Computer Science › Artificial Intelligence › Explainable Artificial Intelligence (XAI)
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiology practices and education
- Keywords
- ChatGPT, large language models, radiology reports, medical text simplification, patient-centered care, factual accuracy, patient harm, radiologist evaluation, patient-doctor interaction, artificial intelligence in radiology
- MeSH terms
- Radiologists, Humans, Physician-Patient Relations, Surveys and Questionnaires, Radiology, Radiology Information Systems, Patient-Centered Care
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-10.
Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-10.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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