Cited by 52Gut microbiota and healthNutritional Studies and DietNutrition, Health and Food Behavior

Obesity and mental health improvement following nutritional education focusing on gut microbiota composition in Japanese women: a randomised controlled trial

Uemura, Mayu, Hayashi, Fumikazu, Ishioka, Ken, Ihara, Kunio, Yasuda, Kazushi, Okazaki, Kanako, Omata, Junichi, Suzutani, Tatsuo +4 more·2019·European Journal of Nutrition

Abstract

Purpose Gut microbiota composition was supposedly related to obesity and psychological factors. We examined the effects of a nutritional education intervention focusing on gut microbiota composition on obesity and psychological factors among obese women.Methods Forty-four obese Japanese women aged 40 or older were randomly assigned to either an intervention group (n = 22) or control group (n = 22). The intervention consisted of a 20-min dietary lecture and a 10-min counselling session by registered dieticians, every 2 weeks for eight consecutive weeks. Body weight, height, waist circumference, food frequency, and gut microbiota composition were measured, and self-rated health and psychological factors were scored before and after the intervention.Results All participants completed the 8 week program. After the intervention, dietary fibre intake (p < 0.01), frequency of vegetable consumption (p = 0.020), and frequency of milk and milk product consumption (p < 0.01) increased significantly in the intervention group compared with the control group. Body weight and body mass index (BMI; p < 0.001), waist circumference (p < 0.01), and the depression scale score (p < 0.01) decreased significantly, while significant improvements were found in self-rated health (p = 0.045) and microbiome diversity (p < 0.01).Conclusion Nutritional education focusing on gut microbiota composition may improve obesity and psychological factors in obese women.

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Crossref · 10.1007/s00394-018-1873-0

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  • In an obese population, a nutrition education program focusing on the gut microbiota resulted in a decrease in the depression score and an increase in self-rated health, as well as an increase in alpha-diversity and abundance of beneficial bacteria such as B. bifidum and S. thermophilus.

    “In an obese population, a nutrition education program focusing on the gut microbiota (increase in fiber-containing and fermented foods) resulted in a decrease in the depression score and an increase in selfrated health, as well as an increase in α-diversity and abundance of beneficial bacteria such as B. bifidum and S. thermophilus (332).”

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Authors
Uemura, M., Hayashi, F., Ishioka, K., Ihara, K., Yasuda, K., Okazaki, K., Omata, J., Suzutani, T., Hirakawa, Y., Chiang, C., Aoyama, A., & Ohira, T.
Affiliations
  • Fukushima Medical University (JP)
  • Center for Gene Research, Nagoya University (JP)
  • Tosei General Hospital (JP)
  • Nagoya University (JP)
Corresponding author
Uemura, Mayu
Venue
European Journal of Nutrition
Published
2018-12-06
Volume
58
Issue
8
Pages
3291-3302
ISSN
  • 1436-6207 (ISSN-L)
  • 1436-6215
OpenAlex
W2902804186
Cited by
52
References
38
Citations by year
2026: 4 · 2025: 7 · 2024: 4 · 2023: 9 · 2022: 14 · 2021: 8 · 2020: 5 · 2019: 1
FWCI
1.24
Type
journal article
Language
en
Open access
closed
Locations
  • European Journal of Nutrition (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • THE SKYLARK FOOD SCIENCE INSTITUTE
  • Fostering Research Fund at Fukushima Medical University
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
Keywords
obesity, gut microbiota, nutrition education, nutrition counseling, depression, self-rated health, dietary fiber intake, vegetable consumption, milk consumption, microbiome diversity, body mass index, waist circumference, Japanese women
MeSH terms
Gastrointestinal Microbiome, Adult, Mental Disorders, Diet, Female, Humans, Japan, Obesity, Patient Education as Topic, Treatment Outcome

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