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Cited by 12Advanced Neuroimaging Techniques and ApplicationsFunctional Brain Connectivity StudiesCerebrovascular and genetic disorders

In vivo probabilistic atlas of white matter tracts of the human subthalamic area combining track density imaging and optimized diffusion tractography

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Basile, Gianpaolo Antonio, Quartu, Marina, Bertino, Salvatore, Serra, Maria Pina, Trucas, Marcello, Boi, Marianna, Demontis, Roberto, Bramanti, Alessia +4 more·2022·Brain Structure and Function
DOI 10.1007/s00429-022-02561-3PMC PMC9618529
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Abstract

The human subthalamic area is a region of high anatomical complexity, tightly packed with tiny fiber bundles. Some of them, including the pallidothalamic, cerebello-thalamic, and mammillothalamic tracts, are relevant targets in functional neurosurgery for various brain diseases. Diffusion-weighted imaging-based tractography has been suggested as a useful tool to map white matter pathways in the human brain in vivo and non-invasively, though the reconstruction of these specific fiber bundles is challenging due to their small dimensions and complex anatomy. To the best of our knowledge, a population-based, in vivo probabilistic atlas of subthalamic white matter tracts is still missing. In the present work, we devised an optimized tractography protocol for reproducible reconstruction of the tracts of subthalamic area in a large data sample from the Human Connectome Project repository. First, we leveraged the super-resolution properties and high anatomical detail provided by short tracks track-density imaging (stTDI) to identify the white matter bundles of the subthalamic area on a group-level template. Tracts identification on the stTDI template was also aided by visualization of histological sections of human specimens. Then, we employed this anatomical information to drive tractography at the subject-level, optimizing tracking parameters to maximize between-subject and within-subject similarities as well as anatomical accuracy. Finally, we gathered subject level tracts reconstructed with optimized tractography into a large-scale, normative population atlas. We suggest that this atlas could be useful in both clinical anatomy and functional neurosurgery settings, to improve our understanding of the complex morphology of this important brain region.

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  • Structures of the basal ganglia and the cerebellum are part of a complex circuitry involved in sensorimotor integration and may take part in integrative processes related to PPS processing.

    “Structures of the basal ganglia and the cerebellum are part of a complex circuitry involved, among other functions, in sensorimotor integration (Milardi et al. 2019; Basile et al. 2022b), and they may take part in integrative processes related to PPS processing.”

    From Neuroanatomical correlates of peripersonal space: bridging the gap between perception, action, emotion and social cognition (2024) · cites this paper as Basile et al. 2022b

    The Introduction (page unavailable) describes pathways from the globus pallidus and cerebellum to the thalamus, and the Results section on the medial lemniscus describes a somatosensory pathway. These passages support the circuitry described, but do not establish that the basal ganglia and cerebellum jointly perform sensorimotor integration. The PPS suggestion follows the citations in the citing sentence and is not attributed to this source. (LLM, conf=0.76)

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Research works printed but not linked: 90

  1. Al-Fatly B Ewert S Kübler D Connectivity profile of thalamic deep brain stimulation to effectively treat essential tremor Brain 2019 10.1093/brain/awz236 31377766 · DOI
  2. Aquino CC Duffley G Hedges DM Interleaved deep brain stimulation for dyskinesia management in Parkinson’s disease Mov Disord 2019 34 1722 1727 10.1002/mds.27839 31483534 PMC10957149 · DOI
  3. Aufenberg C Sarnthein J Morel A A revival of Spiegel’s campotomy: long term results of the stereotactic pallidothalamic tractotomy against the parkinsonian thalamocortical dysrhythmia Thalamus Relat Syst 2005 3 121 10.1017/S147292880700012X · DOI
  4. Avants BB Epstein CL Grossman M Gee JC Symmetric diffeomorphic image registration with cross-correlation: evaluating automated labeling of elderly and neurodegenerative brain Med Image Anal 2008 10.1016/j.media.2007.06.004 17659998 PMC2276735 · DOI
  5. Aviles-Olmos I Kefalopoulou Z Tripoliti E Long-term outcome of subthalamic nucleus deep brain stimulation for Parkinson’s disease using an MRI-guided and MRI-verified approach J Neurol Neurosurg Psychiatry 2014 10.1136/jnnp-2013-306907 24790212 PMC4451170 · DOI
  6. Basile GA Bertino S Bramanti A In vivo super-resolution track-density imaging for thalamic nuclei identification Cereb Cortex 2021 10.1093/cercor/bhab184 34296740 · DOI
  7. Basile GA Quartu M Bertino S Red nucleus structure and function: from anatomy to clinical neurosciences Brain Struct Funct 2021 226 69 91 10.1007/s00429-020-02171-x 33180142 PMC7817566 · DOI
  8. Bertino S Basile GA Anastasi G Anatomical characterization of the human structural connectivity between the pedunculopontine nucleus and globus pallidus via multi-shell multi-tissue tractography Medicina (b Aires) 2020 56 452 10.3390/medicina56090452 PMC7557768 32906651 · DOI
  9. Bertino S Basile GA Bramanti A Spatially coherent and topographically organized pathways of the human globus pallidus Hum Brain Mapp 2020 41 4641 4661 10.1002/hbm.25147 32757349 PMC7555102 · DOI
  10. Bertino S Basile GA Bramanti A Ventral intermediate nucleus structural connectivity-derived segmentation: anatomical reliability and variability Neuroimage 2021 243 118519 10.1016/j.neuroimage.2021.118519 34461233 · DOI
  11. Bond AE Shah BB Huss DS Safety and efficacy of focused ultrasound thalamotomy for patients with medication-refractory, tremor-dominant Parkinson disease a randomized clinical trial JAMA Neurol 2017 74 1412 1418 10.1001/jamaneurol.2017.3098 29084313 PMC5822192 · DOI
  12. Cacciola A Bertino S Basile GA Mapping the structural connectivity between the periaqueductal gray and the cerebellum in humans Brain Struct Funct 2019 10.1007/s00429-019-01893-x 31165919 PMC6591182 · DOI
  13. Calamante F Track-weighted imaging methods: extracting information from a streamlines tractogram Magn Reson Mater Physics, Biol Med 2017 30 317 335 10.1007/s10334-017-0608-1 28181027 · DOI
  14. Calamante F Tournier JD Jackson GD Connelly A Track-density imaging (TDI): super-resolution white matter imaging using whole-brain track-density mapping Neuroimage 2010 10.1016/j.neuroimage.2010.07.024 20643215 · DOI
  15. Calamante F Tournier J-D Heidemann RM Track density imaging (TDI): validation of super resolution property Neuroimage 2011 56 1259 1266 10.1016/j.neuroimage.2011.02.059 21354314 · DOI
  16. Calamante F Tournier J-D Kurniawan ND Super-resolution track-density imaging studies of mouse brain: comparison to histology Neuroimage 2012 59 286 296 10.1016/j.neuroimage.2011.07.014 21777683 · DOI
  17. Calamante F Tournier JD Smith RE Connelly A A generalised framework for super-resolution track-weighted imaging Neuroimage 2012 10.1016/j.neuroimage.2011.08.099 21925280 · DOI
  18. Calamante F Oh S-H Tournier J-D Super-resolution track-density imaging of thalamic substructures: comparison with high-resolution anatomical magnetic resonance imaging at 7.0T Hum Brain Mapp 2013 34 2538 2548 10.1002/hbm.22083 23151892 PMC6870533 · DOI
  19. Chung BS Park JS Whole course of pallidothalamic tracts identified on the sectioned images and surface models Clin Anat 2020 33 66 76 10.1002/ca.23468 31573101 · DOI
  20. Cury RG Fraix V Castrioto A Thalamic deep brain stimulation for tremor in Parkinson disease, essential tremor, and dystonia Neurology 2017 89 1416 1423 10.1212/WNL.0000000000004295 28768840 · DOI
  21. Dai J-K Wang S-X Shan D Super-resolution track-density imaging reveals fine anatomical features in tree shrew primary visual cortex and hippocampus Neurosci Bull 2018 34 438 448 10.1007/s12264-017-0199-x 29247318 PMC5960443 · DOI
  22. Descoteaux M Deriche R Knösche TR Anwander A Deterministic and probabilistic tractography based on complex fibre orientation distributions IEEE Trans Med Imaging 2009 10.1109/TMI.2008.2004424 19188114 · DOI · Paper page
  23. Dice LR Measures of the amount of ecologic association between species Ecology 1945 10.2307/1932409 · DOI
  24. Dyrby TB Lundell H Burke MW Interpolation of diffusion weighted imaging datasets Neuroimage 2014 103 202 213 10.1016/j.neuroimage.2014.09.005 25219332 · DOI
  25. Fernández-Miranda JC Wang Y Pathak S Asymmetry, connectivity, and segmentation of the arcuate fascicle in the human brain Brain Struct Funct 2015 220 1665 1680 10.1007/s00429-014-0751-7 24633827 · DOI
  26. Fishman PS Frenkel V Treatment of movement disorders with focused ultrasound J Cent Nerv Syst Dis 2017 10.1177/1179573517705670 28615985 PMC5462491 · DOI
  27. Fonov V Evans A McKinstry R Unbiased nonlinear average age-appropriate brain templates from birth to adulthood Neuroimage 2009 10.1016/s1053-8119(09)70884-5 · DOI
  28. Gallay MN Jeanmonod D Liu J Morel A Human pallidothalamic and cerebellothalamic tracts: anatomical basis for functional stereotactic neurosurgery Brain Struct Funct 2008 10.1007/s00429-007-0170-0 18193279 PMC2494572 · DOI
  29. Gallay MN Moser D Federau C Jeanmonod D Anatomical and technical reappraisal of the pallidothalamic tractotomy with the incisionless transcranial MR-guided focused ultrasound. A technical note Front Surg 2019 10.3389/fsurg.2019.00002 30733946 PMC6353787 · DOI
  30. Girard G Whittingstall K Deriche R Descoteaux M Towards quantitative connectivity analysis: reducing tractography biases Neuroimage 2014 98 266 278 10.1016/j.neuroimage.2014.04.074 24816531 · DOI · Paper page
  31. Glasser MF Sotiropoulos SN Wilson JA The minimal preprocessing pipelines for the human connectome project Neuroimage 2013 80 105 124 10.1016/j.neuroimage.2013.04.127 23668970 PMC3720813 · DOI · Paper page
  32. Granziera C Schmahmann JD Hadjikhani N Diffusion spectrum imaging shows the structural basis of functional cerebellar circuits in the human cerebellum in vivo PLoS One 2009 10.1371/journal.pone.0005101 19340289 PMC2659746 · DOI
  33. Grisot G Haber SN Yendiki A Diffusion MRI and anatomic tracing in the same brain reveal common failure modes of tractography Neuroimage 2021 239 118300 10.1016/j.neuroimage.2021.118300 34171498 PMC8475636 · DOI
  34. Haber S Perspective on basal ganglia connections as described by Nauta and Mehler in 1966: where we were and how this paper effected where we are now Brain Res 2016 1645 4 7 10.1016/j.brainres.2016.04.016 27064077 · DOI
  35. Hassler R Schaltenbrand G Bayley P Anatomy of the thalamus Introduction to stereotaxic operations with an atlas of the human brain 1959 1 Stuttgart, New York, NY Georg Thieme Verlag 230 290
  36. Hau J Sarubbo S Houde JC Revisiting the human uncinate fasciculus, its subcomponents and asymmetries with stem-based tractography and microdissection validation Brain Struct Funct 2017 222 1645 1662 10.1007/s00429-016-1298-6 27581617 · DOI · Paper page
  37. Hirai T Jones EG A new parcellation of the human thalamus on the basis of histochemical staining Brain Res Rev 1989 14 1 34 10.1016/0165-0173(89)90007-6 2720229 · DOI
  38. Holanda VM Okun MS Middlebrooks EH Postmortem dissections of common targets for lesion and deep brain stimulation surgeries Neurosurgery 2020 10.1093/neuros/nyz318 31504849 · DOI
  39. Horn A Fox MD Opportunities of connectomic neuromodulation Neuroimage 2020 221 117180 10.1016/j.neuroimage.2020.117180 32702488 PMC7847552 · DOI · Paper page
  40. Ilinsky I Horn A Paul-Gilloteaux P Human motor thalamus reconstructed in 3D from continuous sagittal sections with identified subcortical afferent territories Eneuro 2018 5 ENEURO.0060-18.2018 10.1523/ENEURO.0060-18.2018 30023427 PMC6049607 · DOI
  41. Jeurissen B Tournier JD Dhollander T Multi-tissue constrained spherical deconvolution for improved analysis of multi-shell diffusion MRI data Neuroimage 2014 10.1016/j.neuroimage.2014.07.061 25109526 · DOI
  42. Jones DK Challenges and limitations of quantifying brain connectivity in vivo with diffusion MRI Imaging Med 2010 2 341 355 10.2217/iim.10.21 · DOI · Paper page
  43. Kamali A Zhang CC Riascos RF Diffusion tensor tractography of the mammillothalamic tract in the human brain using a high spatial resolution DTI technique Sci Rep 2018 8 5229 10.1038/s41598-018-23452-w 29588461 PMC5869722 · DOI
  44. Knösche TR Anwander A Liptrot M Dyrby TB Validation of tractography: comparison with manganese tracing Hum Brain Mapp 2015 36 4116 4134 10.1002/hbm.22902 26178765 PMC5034837 · DOI · Paper page
  45. Kultas-Ilinsky K Ilinsky IA Verney C Glutamic acid decarboxylase isoform 65 immunoreactivity in the motor thalamus of humans and monkeys: γ-aminobutyric acidergic connections and nuclear delineations J Comp Neurol 2011 10.1002/cne.22653 21491431 · DOI
  46. Kwon HG Hong JH Jang SH Mammillothalamic tract in human brain: diffusion tensor tractography study Neurosci Lett 2010 481 51 53 10.1016/j.neulet.2010.06.052 20599587 · DOI
  47. Kwon HG Hong JH Hong CP Dentatorubrothalamic tract in human brain: diffusion tensor tractography study Neuroradiology 2011 53 787 791 10.1007/s00234-011-0878-7 21547376 · DOI
  48. Kwon D-H Paek SH Kim Y-B In vivo 3D reconstruction of the human pallidothalamic and nigrothalamic pathways with super-resolution 7T MR track density imaging and fiber tractography Front Neuroanat 2021 10.3389/fnana.2021.739576 34776880 PMC8579044 · DOI
  49. Lau JC Xiao Y Haast RAM Direct visualization and characterization of the human zona incerta and surrounding structures Hum Brain Mapp 2020 41 4500 4517 10.1002/hbm.25137 32677751 PMC7555067 · DOI
  50. Li N Baldermann JC Kibleur A A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder Nat Commun 2020 10.1038/s41467-020-16734-3 32620886 PMC7335093 · DOI
  51. Li M Ribas EC Zhang Z Tractography of the ansa lenticularis in the human brain Clin Anat 2021 10.1002/ca.23788 34535922 · DOI
  52. Liu Y Li F Luo H Improvement of deep brain stimulation in dyskinesia in Parkinson’s disease: a meta-analysis Front Neurol 2019 10 1 8 10.3389/fneur.2019.00151 30858823 PMC6397831 · DOI
  53. Maffei C Sarubbo S Jovicich J Diffusion-based tractography atlas of the human acoustic radiation Sci Rep 2019 9 4046 10.1038/s41598-019-40666-8 30858451 PMC6411970 · DOI
  54. Mai JK Majtanik M Toward a common terminology for the thalamus Front Neuroanat 2019 10.3389/fnana.2018.00114 30687023 PMC6336698 · DOI
  55. Maier-Hein KH Neher PF Houde J-C The challenge of mapping the human connectome based on diffusion tractography Nat Commun 2017 8 1349 10.1038/s41467-017-01285-x 29116093 PMC5677006 · DOI
  56. Máñez-Miró JU Rodríguez-Rojas R Del Álamo M Present and future of subthalamotomy in the management of Parkinson´s disease: a systematic review Expert Rev Neurother 2021 21 533 545 10.1080/14737175.2021.1911649 33788645 · DOI
  57. Martínez-Fernández R Rodríguez-Rojas R del Álamo M Focused ultrasound subthalamotomy in patients with asymmetric Parkinson’s disease: a pilot study Lancet Neurol 2018 17 54 63 10.1016/S1474-4422(17)30403-9 29203153 · DOI
  58. Meola A Comert A Yeh F-C The nondecussating pathway of the dentatorubrothalamic tract in humans: human connectome-based tractographic study and microdissection validation J Neurosurg 2016 124 1406 1412 10.3171/2015.4.JNS142741 26452117 · DOI
  59. Meola A Yeh FC Fellows-Mayle W Human connectome-based tractographic atlas of the brainstem connections and surgical approaches Neurosurgery 2016 79 437 454 10.1227/NEU.0000000000001224 26914259 · DOI
  60. Middlebrooks EH Domingo RA Vivas-Buitrago T Neuroimaging advances in deep brain stimulation: review of indications, anatomy, and brain connectomics Am J Neuroradiol 2020 41 1558 1568 10.3174/ajnr.A6693 32816768 PMC7583111 · DOI
  61. Morel A Magnin M Jeanmonod D Multiarchitectonic and stereotactic atlas of the human thalamus J Comp Neurol 1997 387 588 630 10.1002/(SICI)1096-9861(19971103)387:4<588::AID-CNE8>3.0.CO;2-Z 9373015 · DOI
  62. Möttönen T Katisko J Haapasalo J Defining the anterior nucleus of the thalamus (ANT) as a deep brain stimulation target in refractory epilepsy: delineation using 3 T MRI and intraoperative microelectrode recording NeuroImage Clin 2015 7 823 829 10.1016/j.nicl.2015.03.001 26082891 PMC4459042 · DOI
  63. Nauta WJH Mehler WR Projections of the lentiform nucleus in the monkey Brain Res 1966 1 3 42 10.1016/0006-8993(66)90103-X 4956247 · DOI
  64. Neudorfer C Maarouf M Neuroanatomical background and functional considerations for stereotactic interventions in the H fields of Forel Brain Struct Funct 2018 223 17 30 10.1007/s00429-017-1570-4 29152666 · DOI
  65. Nieuwenhuys R The human central nervous system 2008 Springer
  66. Nowacki A Schlaier J Debove I Pollo C Validation of diffusion tensor imaging tractography to visualize the dentatorubrothalamic tract for surgical planning J Neurosurg 2019 10.3171/2017.9.JNS171321 29570012 · DOI
  67. Oishi K Mori S Troncoso JC Lenz FA Mapping tracts in the human subthalamic area by 11.7T ex vivo diffusion tensor imaging Brain Struct Funct 2020 225 1293 1312 10.1007/s00429-020-02066-x 32303844 PMC7584118 · DOI
  68. Palesi F Tournier JD Calamante F Contralateral cerebello-thalamo-cortical pathways with prominent involvement of associative areas in humans in vivo Brain Struct Funct 2015 10.1007/s00429-014-0861-2 25134682 PMC4575696 · DOI
  69. Petersen MV Mlakar J Haber SN Holographic reconstruction of axonal pathways in the human brain Neuron 2019 104 1056 1064.e3 10.1016/j.neuron.2019.09.030 31708306 PMC6948195 · DOI
  70. Plantinga BR Roebroeck A Kemper VG Ultra-high field MRI post mortem structural connectivity of the human subthalamic nucleus, substantia Nigra, and globus pallidus Front Neuroanat 2016 10.3389/fnana.2016.00066 27378864 PMC4909758 · DOI
  71. Raffelt D Tournier J-D Fripp J Symmetric diffeomorphic registration of fibre orientation distributions Neuroimage 2011 56 1171 1180 10.1016/j.neuroimage.2011.02.014 21316463 · DOI
  72. Raffelt D Tournier J-D Crozier S Reorientation of fiber orientation distributions using apodized point spread functions Magn Reson Med 2012 67 844 855 10.1002/mrm.23058 22183751 · DOI
  73. Rozanski VE da Silva NM Ahmadi SA The role of the pallidothalamic fibre tracts in deep brain stimulation for dystonia: a diffusion MRI tractography study Hum Brain Mapp 2017 10.1002/hbm.23450 27862612 PMC6867131 · DOI
  74. Sarubbo S De Benedictis A Merler S Structural and functional integration between dorsal and ventral language streams as revealed by blunt dissection and direct electrical stimulation Hum Brain Mapp 2016 37 3858 3872 10.1002/hbm.23281 27258125 PMC6867442 · DOI
  75. Schaper FLWVJ Plantinga BR Colon AJ Deep brain stimulation in epilepsy: a role for modulation of the mammillothalamic tract in seizure control? Neurosurgery 2020 87 602 610 10.1093/neuros/nyaa141 32421806 PMC8210468 · DOI
  76. Schilling KG Janve V Gao Y Histological validation of diffusion MRI fiber orientation distributions and dispersion Neuroimage 2018 165 200 221 10.1016/j.neuroimage.2017.10.046 29074279 PMC5732036 · DOI · Paper page
  77. Schilling KG Gao Y Stepniewska I Anatomical accuracy of standard-practice tractography algorithms in the motor system - a histological validation in the squirrel monkey brain Magn Reson Imaging 2019 55 7 25 10.1016/j.mri.2018.09.004 30213755 PMC6855403 · DOI
  78. Schlaier JR Beer AL Faltermeier R Probabilistic vs. deterministic fiber tracking and the influence of different seed regions to delineate cerebellar-thalamic fibers in deep brain stimulation Eur J Neurosci 2017 10.1111/ejn.13575 28391647 · DOI
  79. Sotiropoulos SN Jbabdi S Xu J Advances in diffusion MRI acquisition and processing in the human connectome project Neuroimage 2013 10.1016/j.neuroimage.2013.05.057 23702418 PMC3720790 · DOI
  80. Taira T Deep brain stimulation for dystonia Deep brain stimulation for neurological disorders: theoretical background and clinical application 2015 Springer 121 134
  81. Tang Y Sun W Toga AW A probabilistic atlas of human brainstem pathways based on connectome imaging data Neuroimage 2018 169 227 239 10.1016/j.neuroimage.2017.12.042 29253653 PMC5856609 · DOI
  82. Thomas C Ye FQ Irfanoglu MO Anatomical accuracy of brain connections derived from diffusion MRI tractography is inherently limited Proc Natl Acad Sci 2014 111 16574 16579 10.1073/pnas.1405672111 25368179 PMC4246325 · DOI · Paper page
  83. Tournier JD Yeh CH Calamante F Resolving crossing fibres using constrained spherical deconvolution: validation using diffusion-weighted imaging phantom data Neuroimage 2008 42 617 625 10.1016/j.neuroimage.2008.05.002 18583153 · DOI
  84. Tournier J-D Calamante F Connelly A MRtrix: diffusion tractography in crossing fiber regions Int J Imaging Syst Technol 2012 22 53 66 10.1002/ima.22005 · DOI · Paper page
  85. Uǧurbil K Xu J Auerbach EJ Pushing spatial and temporal resolution for functional and diffusion MRI in the human connectome project Neuroimage 2013 80 80 104 10.1016/j.neuroimage.2013.05.012 23702417 PMC3740184 · DOI · Paper page
  86. Van Essen DC Ugurbil K Auerbach E The human connectome project: a data acquisition perspective Neuroimage 2012 62 2222 2231 10.1016/j.neuroimage.2012.02.018 22366334 PMC3606888 · DOI
  87. Van Essen DC Smith SM Barch DM The WU-Minn human connectome project: an overview Neuroimage 2013 80 62 79 10.1016/j.neuroimage.2013.05.041 23684880 PMC3724347 · DOI · Paper page
  88. Velasco FC Molina-Negro P Bertrand C Hardy J Further definition of the subthalamic target for arrest of tremor J Neurosurg 1972 36 184 191 10.3171/jns.1972.36.2.0184 4550420 · DOI
  89. Velasco F Velasco M Machado JP A statistical outline of the subthalamic target for the arrest of tremor Appl Neurophysiol 1975 38 38 46 1108791
  90. Yeh F-C Panesar S Fernandes D Population-averaged atlas of the macroscale human structural connectome and its network topology Neuroimage 2018 178 57 68 10.1016/j.neuroimage.2018.05.027 29758339 PMC6921501 · DOI

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Authors
Basile, G. A., Quartu, M., Bertino, S., Serra, M. P., Trucas, M., Boi, M., Demontis, R., Bramanti, A., Anastasi, G. P., Milardi, D., Ciurleo, R., & Cacciola, A.
Affiliations
  • University of Messina (IT)
  • University of Cagliari (IT)
  • University of Salerno (IT)
  • Centro Neurolesi Bonino Pulejo (IT)
Corresponding author
  • Basile, Gianpaolo Antonio
  • Cacciola, Alberto
ORCID
Venue
Brain Structure and Function
Publisher
Springer Science and Business Media LLC
Published
2022-09-17
Volume
227
Issue
8
Pages
2647-2665
ISSN
  • 1863-2653 (ISSN-L)
  • 1863-2661
DOI
10.1007/s00429-022-02561-3
PMC
PMC9618529
OpenAlex
W4296162502
Cited by
12
References
5
Citations by year
2026: 2 · 2025: 1 · 2024: 7 · 2023: 2
FWCI
1.42
Type
journal article
Language
en
Open access
Licence
Locations
  • Brain Structure and Function (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • UNICA IRIS Institutional Research Information System (University of Cagliari) (submittedVersion, other-oa)
Funders
  • Università degli Studi di Cagliari
  • National Institutes of Health (5u54mh091657-05, 1U54‐MH‐091657)
  • McDonnell Center for Systems Neuroscience (1U54MH091657)
  • NIH Blueprint for Neuroscience Research (1U54-MH-091657)
Topics
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
  • Health Sciences › Medicine › Neurology › Cerebrovascular and genetic disorders
Keywords
white matter tracts, probabilistic atlas, diffusion tractography, mammillothalamic tract, functional neurosurgery, Human Connectome Project, histopathological confirmation
MeSH terms
Brain, Cerebellum, Humans, Diffusion Tensor Imaging, Connectome, White Matter

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