Psychological interventions for endometriosis-related symptoms: a systematic review with narrative data synthesis
Open accessAbstract
Endometriosis impacts the physical, psychological and quality of life domains of women. Despite the medical and/or surgical management of endometriosis, the presence of persistent pelvic pain and psychological distress often continues, suggesting a role for psychological interventions in treatment planning. The present study aimed to conduct the first systematic review, with narrative data synthesis, on psychological interventions for endometriosis-related symptoms. The study also aimed to determine the effectiveness of current interventions in resolving psychological and pain-related loss of function associated with endometriosis and to identify gaps in the literature requiring further research. A total of 15,816 studies were retrieved through database searching and handsearching, with two researchers identifying 11 full-text studies that met inclusion criteria. Three studies of 'moderate' quality were identified, although the overall quality of studies was found to be 'weak', with a 'high' risk of bias. The findings regarding the effectiveness of psychological interventions for endometriosis-related symptoms remain inconclusive. Further research into psychological interventions for women with endometriosis that employ evidence-based protocols with high intervention integrity is recommended.
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There is severely limited evidence for the use of cognitive behavioral therapy, acceptance and commitment therapy, and mindfulness therapies in women with persistent pelvic pain.
“despite severely limited evidence for the use of these psychological interventions in this client group.”
From Psychological interventions for women with persistent pelvic pain: A survey of mental health clinicians (2021) · cites this paper as [12]
There is a lack of high-quality evidence regarding predictors of mental health outcomes and efficacy of mental health interventions for women with PPP conditions.
“Recent reviews have concluded that there is a lack of high-quality evidence regarding predictors of mental health outcomes and efficacy of mental health interventions for women with PPP conditions.11–13”
From Psychological interventions for women with persistent pelvic pain: A survey of mental health clinicians (2021) · cites this paper as [12]
Systematic reviews in this area have all concluded that the evidence for mental health interventions and techniques for use with women with PPP conditions is weak.
“Systematic reviews in this area have all concluded that the evidence for mental health interventions and techniques for use with women with PPP conditions is weak.11–13”
From Psychological interventions for women with persistent pelvic pain: A survey of mental health clinicians (2021) · cites this paper as [12]
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Sechi, C., Ahmad, M., Rosas, I., & Vismara, L. (2024) · Journal of Endometriosis and Pelvic Pain Disorders · doi:10.1177/22840265241282745 · Cited by 1 · see citing works
Dowding, C., Mikocka‐Walus, A. A., Skvarc, D., O’Shea, M., OLIVE, L. S., & Evans, S. (2025) · Counselling Psychology Quarterly · doi:10.1080/09515070.2025.2536559 · Cited by 1 · see citing works
da Luz, C. M., Matias, T. S., de Paula, R. R., Araújo, J., Nascimento, F. C., de Oliveira, Y. V., Camargos, E., Freitas, C. D., & Karloh, M. (2025) · PLoS ONE · doi:10.1371/journal.pone.0330446 · Cited by 1 · see citing works
Niekerk, L. M. V., Cheah, S., Mikocka‐Walus, A. A., Mertens, B., & Evans, S. (2025) · CBT: science into practice · doi:10.1007/978-3-031-98876-9_5 · Cited by 1 · see citing works
Reusing and repurposing of glass waste: A literature review
Sood, T., & Gurmu, A. T. (2022) · World Construction Symposium (WCS) · doi:10.31705/wcs.2022.56 · Cited by 1 · see citing works
Directive clinique no 445 : Gestion de la douleur pelvienne chronique
Allaire, C., Yong, P. J., Bajzak, K. I., Jarrell, J. F., Lemos, N. L. B. M., Miller, C., Morin, M., Nasr‐Esfahani, M., Singh, S. S., & Chen, I. (2024) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/j.jogc.2023.102284
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Planning Life Around Endo: The Impact of Endometriosis on Relationships
Noble, N., Winkelman, L., Jennings, S. L., & Grady, S. E. (2026) · The Family Journal · doi:10.1177/10664807261436789
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- Authors
- Van Niekerk, L., Weaver-Pirie, B., & Matthewson, M.
- Affiliations
- University of Tasmania (AU)
- ORCID
- Matthewson, Mandy
- Venue
- Archives of Women's Mental Health
- Published
- 2019-05-12
- Volume
- 22
- Issue
- 6
- Pages
- 723-735
- ISSN
- 1434-1816 (ISSN-L)
- 1435-1102
- OpenAlex
- W2945321085
- Cited by
- 52
- References
- 53
- Citations by year
- 2026: 3 · 2025: 12 · 2024: 11 · 2023: 9 · 2022: 9 · 2021: 4 · 2020: 4
- FWCI
- 0.60
- Type
- journal article
- Language
- en
- Open access
- green
- figshare.com
- Licence
- Locations
- Archives of Women s Mental Health (publishedVersion)
- PubMed (publishedVersion)
- UTAS Research Repository (submittedVersion)
- Figshare (submittedVersion, cc-by)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Menstrual Health and Disorders
- Keywords
- endometriosis, psychological intervention, pelvic pain, psychological distress, quality of life, loss of function, women's mental health, intervention effectiveness
- MeSH terms
- Endometriosis, Female, Humans, Quality of Life, Pelvic Pain, Young Adult
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