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Cited by 40HIV/AIDS Research and InterventionsMedication Adherence and ComplianceMobile Health and mHealth Applications

Feasibility of Real Time Medication Monitoring Among HIV Infected and TB Patients in a Resource-Limited Setting

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de Sumari-de Boer, I. Marion, van den Boogaard, Jossy, Ngowi, Kennedy M., Semvua, Hadija H., Kiwango, Krisanta W., Aarnoutse, Rob E., Nieuwkerk, Pythia T., Kibiki, Gibson S.·2016·AIDS and Behavior
DOI 10.1007/s10461-015-1254-0
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Abstract

HIV infected and tuberculosis (TB) patients need high levels of treatment adherence to achieve optimal treatment outcomes. We conducted a pilot-study on real time medication monitoring (RTMM) in a resource-limited setting. We enrolled five HIV infected and five TB patients from Kilimanjaro, Tanzania. They took their medication using RTMM. When the device was not opened on time, patients received a reminder SMS. After 3 months, we interviewed patients. Six patients (60 %) reached adherence of >95 %. Nine-hundred-twenty-two of 1104 intakes (84 %) were on time. Five-hundred reminders (45 %) were sent, of which 202 (40 %) were incorrect, because of an unstable mobile network. Nine patients found the device helpful and nine mentioned it keeps medication safe. Six patients reported that the size was too big. Five patients mentioned they received incorrect reminders. The device is considered useful in Kilimanjaro. Optimization of the device should consider network connectivity and the size of the device.

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Authors
de Sumari-de Boer, I. M., van den Boogaard, J., Ngowi, K. M., Semvua, H. H., Kiwango, K. W., Aarnoutse, R. E., Nieuwkerk, P. T., & Kibiki, G. S.
Affiliations
  • Kilimanjaro Clinical Research Institute (TZ)
  • Radboud University Medical Center (NL)
  • Amsterdam University Medical Centers (NL)
ORCID
Venue
AIDS and Behavior
Publisher
Springer Science and Business Media LLC
Published
2015-11-24
Volume
20
Issue
5
Pages
1097-1107
ISSN
  • 1090-7165 (ISSN-L)
  • 1573-3254
DOI
10.1007/s10461-015-1254-0
OpenAlex
W2173188384
Semantic Scholar
f2b2e3e57dcb60ee59b82c92f46cefc33d15de4a
Cited by
40
References
8
Citations by year
2026: 2 · 2025: 3 · 2024: 5 · 2023: 8 · 2022: 3 · 2021: 3 · 2020: 2 · 2019: 3 · 2018: 6 · 2017: 4 · 2015: 1
FWCI
2.86
Type
journal article
Language
en
Open access
Licence
Locations
  • AIDS and Behavior (publishedVersion)
  • PubMed (publishedVersion)
  • Pure Amsterdam UMC (publishedVersion, other-oa)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
  • Radboud Repository (Radboud University) (submittedVersion)
Funders
Dutch Aidsfonds (20130003)
Topics
  • Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
  • Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
  • Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
Keywords
medication adherence, HIV, tuberculosis, SMS reminders, mobile health, resource-limited settings, patient acceptability, mobile network connectivity, drug safety
MeSH terms
Adult, Feasibility Studies, Female, Humans, Male, Middle Aged, Patient Compliance, Pilot Projects, Prospective Studies, Tanzania, Tuberculosis, HIV Infections, Treatment Outcome, Drug Monitoring, Reminder Systems, Text Messaging

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