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Cited by 150

The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.

Heme acquisition by hemophores

Cescau, S., Cwerman, H., Létoffé, S., Delepelaire, P., Wandersman, C., Biville, F.·2007·BioMetals
DOI 10.1007/s10534-006-9050-y
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Abstract

Bacterial hemophores are secreted to the extracellular medium, where they scavenge heme from various hemoproteins due to their higher affinity for this compound, and return it to their specific outer membrane receptor. HasR, the outer membrane receptor of the HasA hemophore, assumes multiple functions which require various energy levels. Binding of heme and, of heme-free or heme-loaded hemophores is energy-independent. Heme transfer from the holo-hemophore to the outer membrane receptor is also energy-independent. In contrast, heme transport and hemophore release require basal or high levels of TonB and proton motive force, respectively. In addition, HasR is a component of a signaling cascade, regulating expression of the has operon via specific sigma and anti-sigma factors encoded by genes clustered at the has operon. The signal is the heme landing on HasR in the presence of the hemophore in its apo form. The has system is the only system thus far characterized in which the anti-sigma factor is submitted to the same signaling cascade as the target operon. Specific autoregulation of the has system, combined with negative regulation by the Fur protein, permits bacterial adaptation to the available iron source. In the presence of a heme-loaded hemophore, inactive anti-sigma factor is accumulated and can be activated as soon as the heme source dries up. Hence, the has system, instead of being submitted to amplification like other systems regulated by sigma anti-sigma factors, fu…

Overview

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Registry

Crossref · 10.1007/s10534-006-9050-y

Cites

34 of 34 references verified0 citation errors · 0 not checkable

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Citations

Cites

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Metadata

Authors
Cescau, S., Cwerman, H., Létoffé, S., Delepelaire, P., Wandersman, C., & Biville, F.
Venue
BioMetals
Publisher
Springer Science and Business Media LLC
Published
2007-02-01
Volume
20
Issue
3-4
Pages
603-613
ISSN
  • 0966-0844
  • 1572-8773
DOI
10.1007/s10534-006-9050-y
Cited by
150
References
34
Language
en
Licence
www.springer.com/tdm (tdm)

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.