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The Impact of Covid-19 Experiences and Associated Stress on Anxiety, Depression, and Functional Impairment in American Adults
Open accessAbstract
Background The COVID-19 pandemic has had a profound impact on health and well-being worldwide and there is increasing recognition of the need to understand the psychological impact of COVID-19 experiences and stress in addition to the physical health consequences.Methods The present study examined how experiences related to COVID-19 and associated stress impact, anxiety, depression, and functional impairment in a convenience sample of 565 American adults (57.9% male) recruited through MTURK.Results COVID-19 experiences were consistently associated with higher odds of probable anxiety and depression diagnoses (ORs ≥ 3.0). COVID-19 associated stress also predicted large proportions of variance (R 2 ≥ 30) in anxiety, depression, health anxiety, and functional impairment in latent variable analyses.Conclusions These findings highlight that personal experiences related to the diagnosis of COVID-19, mortality in acquaintances, and COVID-19 associated stress is associated with a greatly elevated risk of emotional disorder symptomatology and that the COVID-19 pandemic may result in increased demand for mental health services.
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“Mental health problems have increased due to the COVID-19 pandemic, prompting numerous disruptions to daily life, unique stressors, increased mental health concerns, and decreased quality of life”
From Examining the effectiveness and acceptability of a group-based ACT intervention delivered by videoconference to international university students during the COVID-19 pandemic. (2024) · cites this paper as Gallagher, Zvolensky, Long, Rogers, & Garey, 2020
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“Several studies showed that during the early months of the pandemic, increased COVID-19 related distress was associated with increased levels of anxiety, stress, and depression (Bitan et al., 2020; Gallagher et al., 2020).”
From The association between facets of mindfulness and COVID-19 related distress: A cross-sectional study (2023) · cites this paper as Gallagher et al., 2020
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Sebastião, R., Neto, D. D., & Costa, V. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20105819 · Cited by 9
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“…or other causes, were reported to be at risk of functional impairment if they exhibited symptoms of separation distress or post-traumatic stress disorder (Breen et al., 2021; Caycho-Rodr � ıguez et al., 2023; Gallagher et al., 2020; Lee & Neimeyer, 2022; Neimeyer & Lee, 2022; Padala et al., 2020).”
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BackgroundRedução da renda familiar dos professores da educação básica de Minas Gerais na pandemia da Covid-19
Lima, C. D. A., Oliveira, A. J. S., de Freitas, W. M. L., Lopes, H. H. S., dos Montes, G. A., Silva, P. G., Lima, C. A. G., Filho, G. A. L., Parrela, E. D. C. S., Haikal, D. S., et al. (2021) · Trabalho Educação e Saúde · doi:10.1590/1981-7746-sol00329 · Cited by 8
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Contact with Nature in Social Deprivation during COVID-19: The Positive Impact on Anxiety
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Opioid and cannabis co-use: The role of opioid use to cope with negative affect
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Faraj, T. A. (2022) · Wiadomości Lekarskie · doi:10.36740/wlek202204111 · Cited by 6
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ResultThe perceived long-term impact of COVID-19 on OCD symptomology
Dennis, D., McGlinchey, E. L., & Wheaton, M. G. (2023) · Journal of Obsessive-Compulsive and Related Disorders · doi:10.1016/j.jocrd.2023.100812 · Cited by 6
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Yaşlılar ve Yetişkinlerde Koronavirüs (Covid-19) Salgınının Etkileri ve Koronavirüs Korkusu
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“…prompting numerous disruptions to daily life, unique stressors, increased mental health concerns, and CONTACT Francesca Brandolin francesca.f.brandolin@jyu.com; francesca.brandolin@gmail.com decreased quality of life (Gallagher, Zvolensky, Long, Rogers, & Garey, 2020; White & Van Der Boor, 2020).”
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COVID-19 Pandemic Psychosocial Impact Scale: Scale Development and Reliability and Validity Study
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“14,15 Again when we look at the literature, there are some scales developed to measure the impact of the COVID-19 pandemic on people or adapted to Turkish for which validity and reliability studies have been carried out.”
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“After answering inquiries 1–3 about the issue of burdens, psychotherapists were posed with two open-ended questions (4, 5) that focused on exploring the resources and positive outcomes that may have assisted respondents in effectively coping with the burdens above amid the pandemic.”
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“According to some findings (7-11), such conditions can be a serious obstacle to future military professional activities causing permanent anticipation of danger and prolonged feeling of”
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Gaynor, N., & Fitzgerald, L. M. (2023) · Psychological Reports · doi:10.1177/00332941231203563 · Cited by 5
“…of depression, emotional disorder symptomatology, anxiety, stress, and psychological strain (Bendau et al., 2021; Fountoulakis et al., 2021; Gallagher et al., 2020; Patel et al., 2022; Planchuelo-Gomez et al., 2020; Shevlin et al., 2020; Zacher & Rudolph, 2020; see Robinson et al., 2022…”
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“…dine-in ban, and lockdown protocols implemented during the early stage of the outbreak might have had a more significant impact on individuals’ daily functioning (e.g., work, school, social), activity level, and quality of life, given they had less time to process and adapt to the changes (55, 56).”
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“Participants who reported having received a diagnosis of COVID-19 had the highest odds of a probable anxiety/depression diagnosis (Gallagher et al., 2020).”
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Coulaud, P.-J., Jesson, J., Bolduc, N., Ferlatte, O., Bertrand, K., Salway, T. J., Jauffret‐Roustide, M., & Knight, R. (2023) · PLoS ONE · doi:10.1371/journal.pone.0289547 · Cited by 5
“Participants who had been tested for COVID-19 had higher risk for depression, a result in line with previous studies showing association between depression and COVID-19 contact, symptoms or diagnosis [50, 82].”
ResultAdzrago, D., Chiangong, J., Ormiston, C. K., Dada, O. M., Jones, A., & Williams, F. (2024) · Archives of Public Health · doi:10.1186/s13690-024-01320-6 · Cited by 5
“Our results are consistent with another study that revealed that COVID-19 experiences were associated with greater odds of anxiety/depression diagnoses [53].”
ResultLessons learned during the pandemic: Parental coping and the positive effects of COVID ‐19
Baugh, E. J., Bergeson, C., Johnston, C. A., & Pearce, C. (2024) · Family Relations · doi:10.1111/fare.13074 · Cited by 4
Is the Future Ours to See? Israelis’ Future Perception Following Hamas Massacre
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“Additionally, studies indicate that a positive future outlook serves as a protective factor against PTSD, highlighting the benefits of both individual and national future outlook for mental health and well-being (Gallagher et al., 2020; Israel-Cohen et al., 2016; Segovia et al., 2015).”
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“The situation has given rise to concerns for one’s own health [4,5], and many reports show how COVID-19 and restrictions related to it can affect both psyche and soma [2,6–11].”
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“Individuals who suffer from depression often exhibit a decline in their level of productivity, a diminished ability to engage in interpersonal contact, and a sense of disconnection from social networks [40].”
BackgroundDOES SOCIAL SUPPORT AFFECT PERCEIVED STRESS? A RESEARCH DURING THE COVID-19 PANDEMİC İN TURKEY
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Issues of COVID-19-related distance learning for children with neuronopathic mucopolysaccharidoses
Eisengart, J. B., Esler, A., Ellinwood, N. M., Hudock, R. L., King, K. E., Klein, T. L., Lee, C.-M., Morton, J., Stephens, K., Ziegler, R. S., et al. (2021) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2021.06.012 · Cited by 4
Leading Through Covid-19: The Impact of Pandemic Stress and What Leaders Can Do About It
Fernandez, K. C., & Clerkin, C. (2021) · doi:10.35613/ccl.2021.2044 · Cited by 4
“There has also been a focus on the idea of “COVID-19 associated stress”; for example in one study, researchers found that COVID-related stress was significantly positively related to anxiety, depression, and functional impairment (Gallagher et al., 2020).”
Howard, M. C. (2022) · Diagnosis · doi:10.1515/dx-2022-0077 · Cited by 3
“Many authors have used MTurk to study health perceptions and behaviors, as it can provide diverse and representative samples [31 – 33].”
BackgroundBehandlung des schweren Post-Covid-Syndroms
Adorjan, K., Ruzicka, M., Ibarra, G., & Stubbe, H. C. (2023) · MMW - Fortschritte der Medizin · doi:10.1007/s15006-022-2187-y · Cited by 3
“Schlafstörungen können als eigenständige Komplika tion oder als Hinweis auf Angst oder depressive Stö rung auftreten [20].”
Gruescu, A. C. S., Popoiu, C. M., Levai, M. C., Tudor, R., Fericean, R. M., & Riviș, M. (2023) · Healthcare · doi:10.3390/healthcare11091330 · Cited by 3
“Although we did not find a direct association between vaccination status and the questionnaire scores, other studies have reported that vaccination status can influence parental anxiety and stress levels during the COVID-19 pandemic [29].”
ResultSpezifische Teilhaberisiken und -chancen
Wacker, E., Beck, I., Brandt, M., Köbsell, S., Lippke, S., & Niehaus, M. (2023) · Gesundheitsförderung - Rehabilitation - Teilhabe · doi:10.1007/978-3-658-40760-5_3 · Cited by 3
Buckner, J. D., Shepherd, J. M., Stoneking, F. R., & Zvolensky, M. J. (2023) · Substance Use & Misuse · doi:10.1080/10826084.2023.2275570 · Cited by 3
“Total scores can range from 0 to 20 and the measure had good internal consistency in prior work (Gallagher et al., 2020) and in the current investigation (α = 0.94).”
ResultInfluentialSelf-citationPark, Y.-J., Jung, Y., Kim, M.-D., & Bahk, W. (2022) · Psychiatry Investigation · doi:10.30773/pi.2022.0138 · Cited by 3
The Role of Personality Risk and Protective Factors in Living with Covid-19: A Longitudinal Study
Shulman, S., Stein, J. Y., Melamed, O. C., Muchaeli, Y., & Hakhmigari, M. K. (2023) · Journal of Adult Development · doi:10.1007/s10804-023-09439-6 · Cited by 5
Liu, J., Yu, L., Qiu, T., Luo, Y., Fang, X., Yang, F., Xu, X., & Zeng, Q. (2022) · Annals of Palliative Medicine · doi:10.21037/apm-22-1013 · Cited by 3
The association between facets of mindfulness and COVID-19 related distress: A cross-sectional study
Boekhorst, M. G. B. M., & Duijndam, S. (2023) · Acta Psychologica · doi:10.1016/j.actpsy.2023.103826 · Cited by 2
Jafari, H. S., Heidari, M., Sheikhi, R. A., ZEBARDAST, F., MOHAMMADI, M., & Nemati, S. (2022) · Minerva Psychiatry · doi:10.23736/s2724-6612.22.02344-2 · Cited by 2
Thwin, K. M., Lin, W. T., Kaneko, N., Takehara, S., & Ogawa, H. (2024) · Journal of International Society of Preventive and Community Dentistry · doi:10.4103/jispcd.jispcd_182_24 · Cited by 2
Acute Reactivity of Individuals With High and Low Levels of Ongoing Stress
Naliboff, B. D., Ravichandran, S., Labus, J. S., Hassouna, R., Nevé, B. L., Lourenço, J., Maillard, A., Vaughan, A., Liu, X. C., Mayer, E. A., et al. (2025) · Psychosomatic Medicine · doi:10.1097/psy.0000000000001441 · Cited by 2
Kartol, A., & Söner, O. (2022) · Psicologia Reflexão e Crítica · doi:10.1186/s41155-022-00242-y · Cited by 3
“…have investigated the depression, anxiety, and stress levels of individuals during the COVID-19 pandemic (Arafa et al., 2021; Feng et al., 2020; Gallagher et al., 2020; Lakhan et al., 2020; Satici et al., 2021; Stanton et al., 2020; Verma & Mishra, 2020; Yıldırım & Güler, 2021; Zandifar et …”
BackgroundCOVID-related stressors on career insecurity: The moderating effects of family support and openness
Tian, Y., Luan, Y., & Wang, N. (2022) · Journal of Psychology in Africa · doi:10.1080/14330237.2022.2121482 · Cited by 2
Dao, P. Q., Dat, P. T., & Khoa, N. N. Đ. (2023) · Psychology Health & Medicine · doi:10.1080/13548506.2023.2188231 · Cited by 2
“Many previous studies that found that the negative effects of the epidemic on an individual resulted in a higher level of anxiety (Avery et al., 2020; Gallagher et al., 2020).”
Kim, H.-J., Bang, M., Park, C. I., Pae, C., & Lee, S. (2023) · Psychiatry Investigation · doi:10.30773/pi.2022.0318 · Cited by 2
Bonnell, L. N., Clifton, J., Natkin, L. W., Hitt, J. R., & Littenberg, B. (2024) · Journal of Multimorbidity and Comorbidity · doi:10.1177/26335565231222148 · Cited by 2
“27 Less than a month into the pandemic, a sample of the general population from Italy re-ported worse mental health than before COVID-19.”
BackgroundHearn, R., Selfe, J., Cordero, M. I., & Dobbin, N. (2024) · PLoS ONE · doi:10.1371/journal.pone.0302260 · Cited by 3
Zvolensky, M. J., Robison, J. H., Ayers, Z. S., Senger, A. R., Clausen, B. K., Businelle, M. S., & Gallagher, M. W. (2024) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2024.2360054 · Cited by 2
“Participants signed up to participate in a research study designed to assess mental health during the COVID-19 pandemic (Gallagher et al., 2020, 2022).”
Self-citationOhrt, J. H., Clarke, P. B., Conley, A. H., & Broda, M. D. (2024) · Journal of Mental Health Counseling · doi:10.17744/mehc.46.1.02 · Cited by 2
Minority Stress Experienced by LGBTQ Online Communities during the COVID-19 Pandemic
Yuan, Y., Verma, G., Keller, B., & Aledavood, T. (2023) · Proceedings of the International AAAI Conference on Web and Social Media · doi:10.1609/icwsm.v17i1.22201 · Cited by 6
“Recent studies on the effects of the COVID-19 pandemic show a considerable increase in psychological expressions, including expressions related to mental health issues and support, among the general population (Saha et al. 2020; Gallagher et al. 2020).”
BackgroundAdaptation and psychometric evaluation of the COVID-19 stress scales in Turkish sample
Şahin, M. D., Şen, S., & Güler, D. (2022) · International Journal of Assessment Tools in Education · doi:10.21449/ijate.1067542 · Cited by 2
Jesser, A., Steinböck, A., Pammer, B., Ghorab, T., Weber, M., Schaffler, Y., Probst, T., Felnhofer, A., Kothgassner, O., Pieh, C., et al. (2024) · BMC Psychology · doi:10.1186/s40359-024-01714-9 · Cited by 2
Validation of the Mental Health Checklist (MHCL) during COVID‐19 lockdown
So, C. J., Kim, J., Cifre, A. B., Gonzalez, R. D., Bower, J. L., & Alfano, C. A. (2021) · Journal of Community Psychology · doi:10.1002/jcop.22600 · Cited by 2
“…impact of the COVID‐19 pandemic on mental and physical health outcomes, including increased rates of probable anxiety and depressive disorders (Gallagher et al., 2020; Rossi et al., 2020), trauma/ stressor‐related symptoms (Czeisler et al., 2021; Tan et al., 2020), insomnia (Rossi et al.,…”
BackgroundPsychological Perspectives on COVID-19
Hosseini-Nezhad, S., Safdar, S. F., Hosseini-Nezhad, P., & Luu, L. A. N. (2022) · Contributions to economics · doi:10.1007/978-3-030-89996-7_14 · Cited by 2
Nkrumah, E. N. K., Liu, S., Fiergbor, D. D., & Akoto, L. S. (2022) · Healthcare · doi:10.3390/healthcare10020215 · Cited by 4
Effects of Pre-Existing Social Anxiety on Mental Health Outcomes During the COVID-19 PandemicPreprint
Ho, J. T. K., & Moscovitch, D. A. (2020) · doi:10.31219/osf.io/b6xjm · Cited by 2
Asiri, E. J., Dawria, A., Narapureddy, B. R., Reddy, L. K. V., Zahrani, Y. I., Mugaiahgari, B. K. M., Mohieldin, A., Khan, M. S., Muzammil, K., & Altijani, A. A. G. (2023) · Preprints.org · doi:10.20944/preprints202306.0435.v1 · Cited by 1
Dilasha, K. C., Kaphle, H. P., Shrestha, D., & Neupane, N. (2024) · PLoS ONE · doi:10.1371/journal.pone.0308048 · Cited by 1
Ramirez, O., Cort, M. A., Ashley, G., & Moral, M. A. (2025) · Journal of Religion and Health · doi:10.1007/s10943-025-02283-w · Cited by 1
“The COVID-19 pandemic caused a significant increase in mental health problems (Gallagher et al., 2020; Pfeferbaum & North, 2020; Rajkumar, 2020; Wang et al., 2020).”
Protective Role of Regular Physical Activity on Mental Health During the COVID-19 Pandemic
de Sá, V. R., & Padovan‐Neto, F. E. (2025) · Psychiatric Quarterly · doi:10.1007/s11126-025-10148-4 · Cited by 1
Psychological Distress in Older Adults Living in Puerto Rico during COVID-19
Camacho, D., Morgan, M., Vazquez, J., Moxley, J. H., & Burnette, D. (2025) · Journal of Cross-Cultural Gerontology · doi:10.1007/s10823-025-09539-8 · Cited by 1
“About one-third of our sample reported that someone close to them was diagnosed with COVID-19 but not hospitalized, a finding that was associated with greater psy - chological distress (Burke et al., 2020 ; Gallagher et al., 2020).”
Janowicz, K., Soroko, E., Kleka, P., Dolczewski, M., Borzyszkowski, M., & Borzęcka, A. (2025) · Człowiek i Społeczeństwo · doi:10.14746/cis.2025.59.9 · Cited by 1
Senger, A. R., Jo, D., Zvolensky, M. J., & Gallagher, M. W. (2025) · Cognitive Therapy and Research · doi:10.1007/s10608-025-10644-8 · Cited by 1
“The current study sought to address the gap in the literature by conducting secondary analysis of longitudinal data collected during the COVID-19 pandemic (Gallagher et al., 2020).”
Self-citationImpacts on Employee Well-Being in the Finance Industry Post-pandemic
Law, W., & Cheah, J. S. S. (2025) · Advances in Science, Technology & Innovation/Advances in science, technology & innovation · doi:10.1007/978-3-031-89889-1_16 · Cited by 1
COVID-19 anxiety's influence on obsessive compulsive symptoms among African American young adults
Willis, H. A., Williams, M. L., & Ayala, Y. (2026) · Journal of Affective Disorders · doi:10.1016/j.jad.2026.121596 · Cited by 1
Benzouak, T., Gunpat, S., Briner, E., Thake, J. A., Kisely, S. R., & Rao, S. (2021) · Cureus · doi:10.7759/cureus.19999 · Cited by 1
“In another study from the United States, COVID-19 related stress predicted at least 30% of the variance in anxiety symptoms [6].”
BackgroundCovid-19 Geçirmiş Hekimlerin Deneyimleri Üzerine Bir Araştırma
Güngör, S., & Filiz, M. (2023) · Abant Sosyal Bilimler Dergisi · doi:10.11616/asbi.1216363 · Cited by 1
Du, J., Zheng, X.-N., Choi, J. N., & Xiang, Y. (2023) · International Journal of Behavioral Medicine · doi:10.1007/s12529-023-10210-0 · Cited by 1
“Similarly, the likelihood of developing anxiety and depression is significantly high for those who had been diagnosed with COVID-19 or know someone who was diagnosed with or died from COVID-19 [16].”
Deep Representations of First-person Pronouns for Prediction of Depression Symptom Severity
Ren, X., Burkhardt, H. A., Areán, P. A., Hull, T. D., & Cohen, T. (2023) · PubMed Central · doi:10.48550/arxiv.2310.03232 · Cited by 1
Metadata
- Authors
- Gallagher, M. W., Zvolensky, M. J., Long, L. J., Rogers, A. H., & Garey, L.
- Affiliations
- University of Houston (US)
- The University of Texas MD Anderson Cancer Center (US)
- Corresponding author
- Gallagher, Matthew W.
- Venue
- Cognitive Therapy and Research
- Published
- 2020-08-29
- Volume
- 44
- Issue
- 6
- Pages
- 1043-1051
- ISSN
- 0147-5916 (ISSN-L)
- 1573-2819
- PMC
- PMC7456202
- OpenAlex
- W3081595932
- Cited by
- 262
- References
- 45
- Citations by year
- 2026: 5 · 2025: 20 · 2024: 31 · 2023: 55 · 2022: 61 · 2021: 79 · 2020: 11
- FWCI
- 20.62
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Cognitive Therapy and Research (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- COVID-19 pandemic, anxiety, depression, functional disability, health anxiety, COVID-19 diagnosis, mental health demand, psychological impact of pandemic
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