The Binding of Iron to Perineuronal Nets: A Combined Nuclear Microscopy and Mössbauer Study
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Components of PNNs, such as hyaluronan and chondroitin sulfate, have antioxidant properties and can reduce generation of hydroxyl radical via chelation of transition metals and limit initiation of Haber-Weiss and Fenton's reactions.
“Components of the PNNs, such as hyaluronan and chondroitin sulfate, have antioxidant properties (44,45) and can reduce the generation of hydroxyl radical (OH_) via their capacity to chelate transition metals and limit the initiation of Harber-Weiss and Fenton's reactions.”
From Perineuronal nets protect fast-spiking interneurons against oxidative stress (2013) · cites this paper as [45]
Chondroitin sulfate decreases production of ROS generated by H2O2 or mitochondrial disruption by induction of heme oxygenase-1 through PI3K/Akt pathway.
“Chondroitin sulfate has further been shown to decrease the production of ROS generated by H 2 O 2 or mitochondrial disruption by induction of the antioxidant enzyme heme oxygenase-1 through the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) pathway (45).”
From Perineuronal nets protect fast-spiking interneurons against oxidative stress (2013) · cites this paper as [45]
In normal-aged brain and AD, neurons ensheathed by a PN are less frequently affected by lipofuscin accumulation than neurons without a net.
“we previously observed that both in normal-aged brain and AD neurons ensheathed by a PN are less frequently affected by lipofuscin accumulation than neurons without a net.”
From Aggrecan, link protein and tenascin-R are essential components of the perineuronal net to protect neurons against iron-induced oxidative stress (2014) · cites this paper as [23]
The reduced lipofuscin accumulation in PN-ensheathed neurons suggests a neuroprotective function of PNs against neurodegeneration induced by oxidative stress.
“As lipofuscin is an intralysosomal pigment composed of cross-linked proteins and lipids generated by iron-catalysed oxidative processes, this finding suggests a neuroprotective function of PNs against neurodegeneration induced by oxidative stress.22, 23, 29, 30, 31”
From Aggrecan, link protein and tenascin-R are essential components of the perineuronal net to protect neurons against iron-induced oxidative stress (2014) · cites this paper as [23]
Cites
Algorithms for the rapid simulation of Rutherford backscattering spectra
Doolittle, L. (1985) · Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms · doi:10.1016/0168-583x(85)90762-1 · Cited by 2,811 · see citing works
Copper, iron and zinc in Alzheimer's disease senile plaques
Lovell, M. A., Robertson, J. D., Teesdale, W. J., Campbell, J. L., & Markesbery, W. R. (1998) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(98)00092-6 · Cited by 2,120 · see citing works
Halliwell, B. (2001) · Drugs & Aging · doi:10.2165/00002512-200118090-00004 · Cited by 1,502 · see citing works
Occurrence and Constitution of Natural and Synthetic Ferrihydrite, a Widespread Iron Oxyhydroxide
Jambor, J. L., & Dutrizac, J. E. (1998) · Chemical Reviews · doi:10.1021/cr970105t · Cited by 927 · see citing works
Kakhlon, O., & Cabantchik, Z. I. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)01006-7 · Cited by 839 · see citing works
Lecticans: organizers of the brain extracellular matrix
Yamaguchi, Y. (2000) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000690 · Cited by 642 · see citing works
Perineuronal nets — a specialized form of extracellular matrix in the adult nervous system
Celio, M. R., & Blümcke, I. (1994) · Brain Research Reviews · doi:10.1016/0165-0173(94)90006-x · Cited by 386 · see citing works
Perineuronal nets potentially protect against oxidative stress
Morawski, M., Brückner, M. K., Riederer, P., Brückner, G., & Arendt, T. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.04.017 · Cited by 246 · see citing works
Self-citationBrückner, G., Hausen, D., Härtig, W., Drlicek, M., Arendt, T., & Brauer, K. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00071-8 · Cited by 196 · see citing works
Self-citationIron and iron management proteins in neurobiology
Connor, J. R., Menzies, S. L., Burdo, J. R., & Boyer, P. J. (2001) · Pediatric Neurology · doi:10.1016/s0887-8994(01)00303-4 · Cited by 173 · see citing works
Brückner, G., Bringmann, A., Härtig, W., Köppe, G., Delpech, B., & Brauer, K. (1998) · Experimental Brain Research · doi:10.1007/s002210050463 · Cited by 162 · see citing works
Self-citationMössbauer spectroscopic studies of human haemosiderin and ferritin
Bell, S. H., Weir, M., Dickson, D. P. E., Gibson, J. F., Sharp, G. A., & Peters, T. J. (1984) · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · doi:10.1016/0167-4838(84)90313-3 · Cited by 151 · see citing works
Metabolic, Metallic, and Mitotic Sources of Oxidative Stress in Alzheimer Disease
Smith, M. A., Nunomura, A., Zhu, X., Takeda, A., & Perry, G. L. (2000) · Antioxidants and Redox Signaling · doi:10.1089/15230860050192198 · Cited by 151 · see citing works
Developments in Dynamic Analysis for quantitative PIXE true elemental imaging
Ryan, C. G. (2001) · Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms · doi:10.1016/s0168-583x(01)00374-3 · Cited by 128 · see citing works
The influence of crystallinity on magnetic ordering in natural ferrihydrites
Murad, E., Bowen, L. H., Long, G. J., & Quin, T. G. (1988) · Clay Minerals · doi:10.1180/claymin.1988.023.2.04 · Cited by 104 · see citing works
Quantitative microanalysis of perineuronal nets in brain tissue
Reinert, T., Morawski, M., Arendt, T., & Butz, T. (2003) · Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms · doi:10.1016/s0168-583x(03)01041-3 · Cited by 33 · see citing works
Self-citationSome magnetic properties of the cores of various ferritins
Pierre, T. G. S., Dickson, D. P. E., Webb, J., Kim, K. S., Macey, D. J., & Mann, S. (1986) · Hyperfine Interactions · doi:10.1007/bf02399502 · Cited by 23 · see citing works
Solid State Analysis with the New Leipzig High-Energy Ion Nanoprobe
Vogt, J., Flagmeyer, R.-H., Heitmann, J., Lehmann, D., Reinert, T., Jankuhn, S., Spemann, D., Tr�ger, W., & Butz, T. (2000) · Microchimica Acta · doi:10.1007/s006040070078 · Cited by 18 · see citing works
Self-citationMössbauer studies of biological nanophase magnetic materials
Dickson, D. P. E. (1998) · Hyperfine Interactions · doi:10.1023/a:1012697415903 · Cited by 6 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
In Situ Imaging of Metals in Cells and Tissues
McRae, R. L., Bagchi, P., Sumalekshmy, S., & Fahrni, C. J. (2009) · Chemical Reviews · doi:10.1021/cr900223a · Cited by 566 · see citing works
Perineuronal nets protect fast-spiking interneurons against oxidative stress
Cabungcal, J.-H., Steullet, P., Morishita, H., Kraftsik, R., Cuenod, M., Hensch, T. K., & Do, K. Q. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1300454110 · Cited by 512 · see citing works
Perineuronal Nets Enhance the Excitability of Fast-Spiking Neurons
Balmer, T. S. (2016) · eneuro · doi:10.1523/eneuro.0112-16.2016 · Cited by 220 · see citing works
Suttkus, A., Rohn, S., Weigel, S., Glöckner, P., Arendt, T., & Morawski, M. (2014) · Cell Death & Disease · doi:10.1038/cddis.2014.25 · Cited by 168 · see citing works
Self-citationMorawski, M., Brückner, G., Jäger, C., Seeger, G., Matthews, R. T., & Arendt, T. (2012) · Brain Pathology · doi:10.1111/j.1750-3639.2011.00557.x · Cited by 157 · see citing works
Self-citationAggrecan: Beyond cartilage and into the brain
Morawski, M., Brückner, G., Arendt, T., & Matthews, R. T. (2012) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2012.01.010 · Cited by 136 · see citing works
Self-citationProtective Properties of Neural Extracellular Matrix
Suttkus, A., Morawski, M., & Arendt, T. (2014) · Molecular Neurobiology · doi:10.1007/s12035-014-8990-4 · Cited by 108 · see citing works
Self-citationECM in brain aging and dementia
Morawski, M., Filippov, M., Tzinia, A., Tsilibary, E., & Vargova, L. (2014) · Progress in Brain Research · doi:10.1016/b978-0-444-63486-3.00010-4 · Cited by 84 · see citing works
Self-citationFriedrich, I., Reimann, K., Jankuhn, S., Kirilina, E. P., Stieler, J., Sonntag, M., Meijer, J., Weiskopf, N., Reinert, T., Arendt, T., et al. (2021) · Acta Neuropathologica Communications · doi:10.1186/s40478-021-01145-2 · Cited by 67 · see citing works
Self-citationThe mechanisms of perineuronal net abnormalities in contributing aging and neurological diseases
Dong, Y., Zhao, K., Qin, X., Du, G., & Gao, L. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.102092 · Cited by 38 · see citing works
Chondroitin sulfate proteoglycan-based extracellular matrix in chicken (Gallus domesticus) brain
Morawski, M., Alpár, A., Brückner, G., Fiedler, A., Jäger, C., Gáti, G., Stieler, J., & Arendt, T. (2009) · Brain Research · doi:10.1016/j.brainres.2009.02.046 · Cited by 27 · see citing works
Self-citationReinert, A., Mittag, A., Reinert, T., Tárnok, A., Arendt, T., & Morawski, M. (2011) · Cytometry Part A · doi:10.1002/cyto.a.21047 · Cited by 8 · see citing works
Self-citation
- Authors
- Morawski, M., Reinert, T., Brückner, G., Wagner, F. E., Arendt, T. H., & Tröger, W.
- Affiliations
- Leipzig University (DE)
- Technical University of Munich (DE)
- Corresponding author
- Tröger, W.
- Venue
- Hyperfine Interactions
- Published
- 2005-10-11
- Volume
- 159
- Issue
- 1-4
- Pages
- 285-291
- ISSN
- 0304-3843 (ISSN-L)
- 1572-9540
- OpenAlex
- W2073522336
- Cited by
- 12
- References
- 19
- Citations by year
- 2023: 1 · 2021: 1 · 2016: 1 · 2014: 3 · 2013: 1 · 2012: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Hyperfine Interactions (publishedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Funders
- Deutsche Forschungsgemeinschaft
- Topics
- Health Sciences › Medicine › Hematology › Iron Metabolism and Disorders
- Physical Sciences › Physics and Astronomy › Condensed Matter Physics › Crystallography and Radiation Phenomena
- Physical Sciences › Physics and Astronomy › Radiation › X-ray Spectroscopy and Fluorescence Analysis
- Keywords
- perineuronal nets, iron binding, extracellular matrix, iron(III), iron accumulation, redox-active iron, ion homeostasis, red nucleus, cerebral cortex, Mössbauer spectroscopy, PIXE, rat brain
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
