Cited by 54COVID-19 and Mental HealthChild and Adolescent Psychosocial and Emotional DevelopmentAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Intolerance of Uncertainty and Health-Related Anxiety in Youth amid the COVID-19 Pandemic: Understanding and Weathering the Continuing Storm

Open access
Korte, Ciera, Friedberg, Robert D., Wilgenbusch, Tammy, Paternostro, Jennifer K., Brown, Kimberly, Kakolu, Anusha, Tiller-Ormord, Josh, Baweja, Raman +7 more·2022·Journal of Clinical Psychology in Medical Settings

Abstract

The COVID-19 pandemic is a public health crisis that continues to impact individuals worldwide. While children may be less susceptible to severe medical complications, they are nonetheless vulnerable to stress and anxiety associated with the pandemic. However, current understanding of psychological functioning and potential strategies to mitigate distress amid a pandemic is naturally limited. Consequently, this article is an attempt to fill that gap. Existing literature on pandemics, health-related anxieties, intolerance of uncertainty, and psychopathological sequelae is summarized within the context of the COVID-19 outbreak. Conclusions from the empirical data and emerging theoretical models are reviewed and synthesized. Finally, several potentially engaging and effective examples of developmentally appropriate interventions targeting intolerance of uncertainty and health-related anxieties in pediatric patients during the peri- and post-pandemic periods are described. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Integrity signals

Registry

Crossref · 10.1007/s10880-021-09816-x

Cites

78 of 78 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Claims the paper makes

21 of 50 cited sources checked · 7 supported · 0 flagged · accuracy not yet measured

  • Premisecitation

    IU lays a path toward GAD and SAD.

    “IU also lays a path toward GAD and SAD (Dugas et al., 1998; Carleton, 2016; Evans et al., 2020).”
    Quote in the paperSubstantial claim1 of 3 sources checked
    • cites Dugas et al., 1998 source
    • cites Carleton, 2016 source
    • cites Evans et al., 2020 source
  • Premisecitation

    Emphasis on personal hygiene and handwashing as COVID-19 prevention may increase OCD-related symptoms in children.

    “The emphasis on personal hygiene and handwashing as preventative measures for the spread of the virus may also increase OCD-related symptoms in children (Imran et al., 2020).”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites Imran et al., 2020 source

      In the Introduction section “Children with Pre-existing Mental Illnesses” (page unavailable), the paper says stress may worsen obsessions and compulsions in children with OCD and that disease-mitigation measures can be traumatic. Its “Specific Interventions” section recommends frequent handwashing, but it does not say that emphasis on hygiene or handwashing increases OCD-related symptoms. (LLM, conf=0.86)

      Experimental — accuracy not yet measured
  • Premisecitation

    Radanovic et al. (2021) found that children's worries increased with greater exposure to threat messages from parents and outside sources.

    “Further, Radanovic et al. (2021) found that children’s worries increased with greater exposure to threat messages originating from parents as well as from outside sources (e.g., peers, news reports, internet, social media, etc.).”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites Radanovic et al., 2021 source
  • Premisecitation

    Children with chronic illnesses appear especially vulnerable to IU's adverse effects.

    “Children with chronic illnesses appear especially vulnerable to IU’s adverse effects (Mertens et al., 2020).”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites Mertens et al., 2020 source

      The Introduction (page unavailable) describes intolerance of uncertainty (IU) as a general vulnerability factor for anxiety-related disorders, and the Discussion (page unavailable) reports a trend linking IU to greater fear of coronavirus. Neither passage establishes that children with chronic illnesses are especially vulnerable to IU’s effects; the Discussion’s mention of chronic diseases concerns coronavirus risk, not IU. (LLM, conf=0.84)

      Experimental — accuracy not yet measured
  • Premisecitation

    Osmanağaoğlu et al. (2018) attributed nearly 40% of adolescents' variation in worry to IU.

    “Osmanağaoğlu et al. (2018) attributed nearly 40% of adolescents’ variation in worry to IU.”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites Osmanağaoğlu et al., 2018 source

      Section 3.2 reports that IU was associated with approximately 39.69% of the variance in worry, supporting the nearly 40% figure. However, the meta-analysis covered children and adolescents, not adolescents separately. The Discussion also cautions that its largely cross-sectional evidence cannot establish the direction of the association, so “attributed” should not imply causation. (LLM, conf=0.87)

      Experimental — accuracy not yet measured
  • May combine two claims. 20
  • Classified as probably not a substantial claim. 11
  • May combine two claims.

    Interpretationcitation

    Psychoeducational strategies are especially valuable for treating youth with pandemic-related worries because they empower pediatric patients and initially modify IU.

    “Consequently, psychoeducational strategies are especially valuable for treating youth with pandemic-related worries because they empower pediatric patients and serve to initially modify IU (Radanovic et al, 2021).”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites Radanovic et al, 2021 source

      The Discussion > Implications recommends talking with children about the pandemic in ways that help them understand it and reduce their worries. It does not describe psychoeducation as a treatment for pediatric patients, claim that it empowers them, or discuss initially modifying intolerance of uncertainty (IU). (LLM, conf=0.83)

      Experimental — accuracy not yet measured
  • May combine two claims.

    Premisecitation

    Individuals with high IU find ambiguity unbearable and experience difficulty functioning in uncertain situations.

    “Individuals with high IU find ambiguity unbearable and experience difficulty functioning in uncertain situations (Comer et al., 2009).”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites Comer et al., 2009 source
  • May combine two claims.

    Premisecitation

    Studies show elevated anxiety levels in pediatric populations diagnosed with diabetes, functional abdominal pain, coronary heart disease, and asthma.

    “More specifically, studies show elevated anxiety levels in pediatric populations diagnosed with diabetes (Ducat et al., 2014), functional abdominal pain (Shelby et al., 2013), coronary heart disease (Oliver et al., 2020), and asthma (Pateraki et al., 2018).”
    Quote in the paperNot a substantial claim1 of 3 sources checked
    • cites Ducat et al., 2014 source
    • cites Shelby et al., 2013 source
    • cites Oliver et al., 2020 source
  • May combine two claims.

    Premisecitation

    Doubt and IU are core features of OCD.

    “Doubt and IU are seen as core features of OCD (Gillett et al., 2018; Cervin et al., 2020).”
    Quote in the paperNot a substantial claim1 of 2 sources checked
    • cites Gillett et al., 2018 source
    • cites Cervin et al., 2020 source

      The Discussion describes doubt as central to OCD, and the study finds doubting/checking central in youth symptom networks. It mentions uncertainty alongside doubt but does not identify intolerance of uncertainty (IU) as a core feature. The source therefore supports the doubt portion, not the IU portion. (LLM, conf=0.85)

      Experimental — accuracy not yet measured
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Experts predict a surge in young people seeking clinical care for behavioral health concerns during the peri- and post-pandemic periods.

    “Experts predict a surging number of young people-seeking clinical care for various behavioral health concerns during the peri- and post-pandemic period (Fegert et al., 2020; Golberstein et al., 2020; Loades et al., 2020; Marques de Miranda et al., 2020; Sanderson et al., 2020; Simon et al., 2020; Abbott, 2021).”
    Quote in the paperNot a substantial claim2 of 3 sources checked
    • cites Fegert et al., 2020 source
    • cites Golberstein et al., 2020 source
    • cites Loades et al., 2020 source

      The paper's discussion of policy and practice says COVID-19 containment-related loneliness could lead to subsequent mental health problems in young people. Its Results section also reports that, after earlier infectious-disease outbreaks, some children affected by containment measures needed mental health services. Neither passage predicts a surge in young people seeking clinical care during or after COVID-19. (LLM, conf=0.83)

      Experimental — accuracy not yet measured
  • May combine two claims.

    Premisecitation

    IU contributes to avoidance, reassurance seeking, planning for worst-case scenarios, and excessive caution.

    “Moreover, IU contributes to avoidance, seeking reassurance, planning for worst-case scenarios, and excessive caution (Beesdo‐Baum et al., 2012).”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites Beesdo‐Baum et al., 2012 source

      The Assessments section lists avoidance, reassurance seeking, making plans in case worries come true, and acting carefully as behaviors assessed in patients with generalized anxiety disorder. The Introduction also describes reassurance seeking as a way to reduce uncertainty. But the paper does not establish that intolerance of uncertainty (IU) causes or contributes to those behaviors; it assesses them as responses to worry. (LLM, conf=0.88)

      Experimental — accuracy not yet measured
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Liu et al. (2020) found elevated PTSD and GAD rates among Chinese children and adolescents after the COVID-19 outbreak.

    “For instance, Liu et al. (2020) found elevated PTSD and GAD rates among Chinese children and adolescents after the COVID-19 outbreak.”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites Liu et al., 2020 source

      The Comment section reports that 30% of children isolated or quarantined during earlier pandemic diseases met clinical criteria for PTSD, citing Sprang and colleagues. It does not report PTSD rates among Chinese children after the COVID-19 outbreak or any GAD rates; it discusses those children’s potential mental-health risks instead. Page numbers are unavailable in our copy. (LLM, conf=0.86)

      Experimental — accuracy not yet measured
  • May combine two claims.

    Premisecitation

    CBT approaches to anxiety are empirically supported and widely applicable to diverse pediatric populations.

    “While CBT approaches to anxiety are empirically supported and widely applicable to diverse pediatric populations (Norris & Kendall, 2020), traditionally marginalized populations are often disadvantaged by a lack of access to proper behavioral health care.”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites Norris & Kendall, 2020 source

      The Introduction identifies CBT as a well-established treatment for youth anxiety and reports that most studies found equivalent outcomes across racial and ethnic groups. But it also emphasizes that few studies tested race or ethnicity and that trial samples often lacked diversity, so broad applicability to diverse pediatric populations is not firmly established. (LLM, conf=0.86)

      Experimental — accuracy not yet measured
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Tanir et al. (2020) claimed that cleanliness and handwashing obsessions and compulsions have increased during the viral outbreak.

    “More specifically, Tanir et al. (2020) claimed cleanliness as well as handwashing obsessions and compulsions have increased during the viral outbreak.”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites Tanir et al., 2020 source
  • Probably not a substantial claim: may not pass S2 (checkable). May combine two claims.

    Interpretationreasoning

    IU may be a key variable for conceptualizing young people's health-related concerns during a viral outbreak, and CBT interventions targeting this pathway are potentially good treatment options.

    “Accordingly, IU may be a key variable for conceptualizing young people’s health-related concerns during a viral outbreak and cognitive-behavioral interventions targeting this pathway are potentially good treatment options.”
    Quote in the paperNot a substantial claim
  • Classified as probably not a substantial claim. May combine two claims.

    Premisecitation

    Health pandemics tend to be singular widespread traumatic events, occur in waves, appear indefinite to the public, and have ambiguous endpoints.

    “Taylor (2019) suggested health pandemics share certain features including being singular widespread traumatic events, often marked by waves, apparently indefinite to the public, and characterized by ambiguous endpoints.”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Taylor, 2019

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • Probably not a substantial claim: may not pass S2 (checkable).

    Interpretationreasoning

    Psychoeducation, cognitive restructuring procedures, and exposure/behavioral experiments are likely suitable treatment options.

    “In particular, psychoeducation, cognitive restructuring procedures, and exposure/behavioral experiments are likely suitable treatment options.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Interpretationreasoning

    The coronavirus poses a behavioral health emergency as well as a public health crisis.

    “Thus, the coronavirus poses not only a potential crisis for public health services but a behavioral health emergency as well.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Premisecitation

    IU manifests as worry, emotional distress, ineffective problem solving, and uncertainty avoidance.

    “IU manifests as worry, emotional distress, ineffective problem solving, and uncertainty avoidance (Dugas et al., 1998; Read et al., 2013; Rifkin & Kendall, 2020a, b).”
    Quote in the paperSubstantial claim0 of 3 sources checked
    • cites Dugas et al., 1998 source
    • cites Read et al., 2013 source
    • cites Rifkin & Kendall, 2020a, b source
  • May combine two claims.

    Premisecitation

    Lack of information and misinformation are major catalysts to children's pandemic-related anxieties.

    “A recent study noted that lack of information as well as misinformation are major catalysts to children’s pandemic-related anxieties (Shahrbabaki et al., 2021).”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Shahrbabaki et al., 2021

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Premisecitation

    Health-related anxieties in young patients are relatively common, though care providers are often unfamiliar with them.

    “Although care providers are often unfamiliar with health-related anxieties in young patients, these worries are nonetheless relatively common (Villadsen et al., 2017; Haig-Ferguson et al., 2020).”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites Villadsen et al., 2017 source
    • cites Haig-Ferguson et al., 2020

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • Probably not a substantial claim: may not pass S2 (checkable).

    Interpretationreasoning

    The reviewed literature suggests that a diathesis-stress model could be a useful clinical heuristic for conceptualizing and treating youth distress during the pandemic.

    “The reviewed literature suggests a diathesis-stress model could be a useful clinical heuristic for conceptualizing and treating youth experiencing distress during the pandemic.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Premisecitation

    Uncertainty and health-related anxieties increase during the peri- and post-pandemic periods.

    “Uncertainty and health-related anxieties grow organically in the peri- and post-pandemic periods.”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Taylor, 2019

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Premisecitation

    Although IU serves as a mechanism of action in multiple disorders, its specific function is currently unclear.

    “In sum, although IU serves as a mechanism of action in multiple disorders, the specific function is currently unclear (Palitz et al., 2019b).”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Palitz et al., 2019b source
  • May combine two claims.

    Interpretationreasoning

    Heightened IU propels catastrophizing, magnification of threat, hypervigilance, rumination, worry, reassurance-seeking/checking, fears of loss or lack of control, and avoidance.

    “Heightened IU then propels catastrophizing, magnification of threat, hypervigilance, rumination, worry, reassurance-seeking/checking, fears of loss/lack of control, and avoidance.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Interpretationreasoning

    IU acts as both a causal factor that increases vulnerability to anxiety spectrum symptoms and a maintaining factor that is negatively reinforced through safety-seeking behaviors.

    “Finally, IU acts as both a causal factor by increasing vulnerability to anxiety spectrum symptoms and a maintaining factor by being negatively reinforced via various safety-seeking behaviors (e.g., checking or avoidance).”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S2 (checkable), S4 (based).

    Interpretationreasoning

    A CBT-oriented approach to treatment seems a promising strategy to combat the array of symptoms and potential comorbidities.

    “A CBT-oriented approach to treatment seems a promising strategy to combat the array of symptoms and potential comorbidities.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Premisecitation

    Children's anxiogenic beliefs during the pandemic include thoughts such as fear of dying from COVID-19, anxiety from watching the news, fear of spreading the virus, and worry about being infected.

    “More specifically, children’s anxiogenic beliefs during the pandemic include thoughts such as “I am afraid I am going to die because of COVID-19,” “I get anxious or nervous from watching the news,” “I am afraid I am going to spread the virus to others,” and “I worry about being infected (Shahrbabaki et al., 2021).””
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Shahrbabaki et al., 2021

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Premisecitation

    Catastrophic predictions, overestimations of danger or threat, and what-if thinking are common in anxious youth.

    “Catastrophic predictions, overestimations of danger/threat, and what if thinking are common in anxious youth (Friedberg & McClure, 2015).”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Friedberg & McClure, 2015

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • Classified as probably not a substantial claim.

    Premisecitation

    Exposure-based techniques are ways children and adolescents can show they can tolerate uncertainty and approach previously dreaded experiences.

    “These procedures are ways children and adolescents can “show they can” tolerate uncertainty and approach heretofore dreaded experiences (Kendall et al., 2017).”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Kendall et al., 2017

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Interpretationreasoning

    IU likely represents a diathesis for anxiety-related symptoms and a logical transdiagnostic target for intervention.

    “IU likely represents a diathesis for anxiety-related symptoms and a logical transdiagnostic target for intervention.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S2 (checkable), S4 (based). May combine two claims.

    Interpretationnone given

    Better integration of accessible services into macro-systems such as schools, primary care settings, and community organizations holds potential to improve clinical outcomes and reduce behavioral health inequities in the peri- and post-pandemic periods.

    “Better integration of accessible services into macro-systems such as schools, primary care settings, and community organizations, holds the potential to improve clinical and reduce behavioral health inequities in the peri- as well as post-pandemic periods.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S2 (checkable), S4 (based).

    Interpretationreasoning

    Identifying and treating IU potentially helps ameliorate young people's emotional and behavioral responses to the COVID-19 pandemic.

    “Identifying and treating IU potentially helps ameliorate young peoples’ emotional and behavioral responses to the COVID-19 pandemic.”
    Quote in the paperNot a substantial claim
28 of 28
  • The paper relies on this without support.

    Current understanding of psychological functioning and potential strategies to mitigate distress during a pandemic is limited.

    “However, current understanding of psychological functioning and potential strategies to mitigate distress amid a pandemic is naturally limited.”
  • The paper relies on this without support.

    Models for understanding psychological sequelae associated with global pandemics are under-developed.

    “Models for understanding psychological sequelae associated with global pandemics are under-developed.”
  • The paper relies on this without support.

    Treatment approaches to mitigate distress in the peri- and post-pandemic periods are incipient.

    “Unsurprisingly, treatment approaches to mitigate distress in the peri- and post-pandemic periods are similarly incipient.”
  • The paper relies on this without support.

    The last pandemic hitting the United States occurred over 100 years ago, so theoretical concepts and treatment methods have not been examined in the current viral outbreak context.

    “However, the last pandemic hitting the United States occurred over 100 years ago. Therefore, these theoretical concepts and treatment methods have not been examined in the current context of the viral outbreak.”
  • The paper relies on this without support.

    Understanding of health-related anxieties in young patients is limited but expanding.

    “As the pre-pandemic literature review indicates, the understanding of health-related anxieties in young patients is limited but expanding.”
  • The paper relies on this without support.

    Conceptualization of the psychological mechanisms associated with health-related anxieties is somewhat rudimentary.

    “However, the conceptualization of the psychological mechanisms associated health-related anxieties is somewhat rudimentary.”
  • The paper relies on this without support.

    The state of the science and clinical practice were somewhat caught unprepared because of the unprecedented and sudden nature of the pandemic.

    “However, due to the unprecedented and sudden nature of the pandemic, the state of the science and clinical practice were somewhat caught unprepared.”
7 of 7

Cites

Flagged first, then by citations

2 of the 80 references couldn’t be matched to a known paper.

Research works printed but not linked: 2

  1. Kendall, P.C., Crawford, E.A., Kagan, E.R., Furr, J.M., & Podell, J.L. (2017) Child-focused treatment for anxiety. In J.R Weisz & A.E.Kazdin (Eds.), Evidence-based psychotherapies for children and adolescents (3rd Ed., pp. 17–34). Guilford
  2. Palitz, S. A., Davis, J. P., & Kendall, P. C. (2019a). Anxiety disorders. In M. J. Prinstein, E. A. Youngstrom, E. J. Mash, & R. A. Barkley (Eds.), Treatment of disorders in childhood and adolescence (Fourth edition, pp. 281–310). Guilford.

Cited by

Sorted by citations

Authors
Korte, C., Friedberg, R. D., Wilgenbusch, T., Paternostro, J. K., Brown, K., Kakolu, A., Tiller-Ormord, J., Baweja, R., Cassar, M., Barnowski, A., Movahedi, Y., Kohl, K., Martinez, W., Trafalis, S., & Leykin, Y.
Affiliations
  • Palo Alto University (US)
  • University of Iowa (US)
  • Pennsylvania State University (US)
Corresponding author
Friedberg, Robert D.
Venue
Journal of Clinical Psychology in Medical Settings
Published
2021-09-03
Volume
29
Issue
3
Pages
645-653
ISSN
  • 1068-9583 (ISSN-L)
  • 1573-3572
OpenAlex
W3198672189
Cited by
54
References
80
Citations by year
2026: 6 · 2025: 6 · 2024: 12 · 2023: 19 · 2022: 9 · 2021: 2
FWCI
1.40
Type
journal article
Language
en
Open access
Locations
  • Journal of Clinical Psychology in Medical Settings (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
Topics
  • Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
intolerance of uncertainty, youth, children, anxiety, stress, child mental health
MeSH terms
COVID-19, Adolescent, Anxiety, Anxiety Disorders, Child, Humans, Uncertainty, Pandemics

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