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Impact of HMGB1, RAGE, and TLR4 in Alzheimer’s Disease (AD): From Risk Factors to Therapeutic Targeting

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Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions

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Linking Molecular Pathways and Large-Scale Computational Modeling to Assess Candidate Disease Mechanisms and Pharmacodynamics in Alzheimer's Disease

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Long-term running exercise improves cognitive function and promotes microglial glucose metabolism and morphological plasticity in the hippocampus of APP/PS1 mice

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Role of Toll Like Receptor 4 in Alzheimer’s Disease

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The endotoxin hypothesis of Alzheimer’s disease

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TREM2: Potential therapeutic targeting of microglia for Alzheimer's disease

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TLR4 Targeting as a Promising Therapeutic Strategy for Alzheimer Disease Treatment

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A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene

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TREM2 Deficiency Aggravates NLRP3 Inflammasome Activation and Pyroptosis in MPTP-Induced Parkinson’s Disease Mice and LPS-Induced BV2 Cells

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Dietary Pattern, Gut Microbiota, and Alzheimer’s Disease

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New Insights into Neuroinflammation Involved in Pathogenic Mechanism of Alzheimer’s Disease and Its Potential for Therapeutic Intervention

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The Emerging Role of Curcumin in the Modulation of TLR-4 Signaling Pathway: Focus on Neuroprotective and Anti-Rheumatic Properties

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Toll-Like Receptor 4: A Promising Therapeutic Target for Alzheimer’s Disease

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Microglia and Wnt Pathways: Prospects for Inflammation in Alzheimer’s Disease

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Recent developments in the probiotics as live biotherapeutic products (LBPs) as modulators of gut brain axis related neurological conditions

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Alzheimer’s Disease and Diabetes: Role of Diet, Microbiota and Inflammation in Preclinical Models

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Cordycepin Modulates Microglial M2 Polarization Coupled with Mitochondrial Metabolic Reprogramming by Targeting HKII and PDK2

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Irisin: A Multifaceted Hormone Bridging Exercise and Disease Pathophysiology

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Oxymatrine inhibits neuroinflammation by Regulating M1/M2 polarization in N9 microglia through the TLR4/NF-κB pathway

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Microglial signalling pathway deficits associated with the patient derived R47H TREM2 variants linked to AD indicate inability to activate inflammasome

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Downregulation of TREM2 expression exacerbates neuroinflammatory responses through TLR4-mediated MAPK signaling pathway in a transgenic mouse model of Alzheimer’s disease

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Microglial TLR4/NLRP3 Inflammasome Signaling in Alzheimer’s Disease

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TREM2 Overexpression Attenuates Cognitive Deficits in Experimental Models of Vascular Dementia

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HMGB1/RAGE/TLR4 axis and glutamate as novel targets for PCSK9 inhibitor in high fat cholesterol diet induced cognitive impairment and amyloidosis

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Alzheimer’s disease pathogenesis: standing at the crossroad of lipid metabolism and immune response

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Diabetes: Risk factor and translational therapeutic implications for Alzheimer's disease

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TREM2 Regulates High Glucose-Induced Microglial Inflammation via the NLRP3 Signaling Pathway

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Elevated amyloidoses of human IAPP and amyloid beta by lipopolysaccharide and their mitigation by carbon quantum dots

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TPM1 mediates inflammation downstream of TREM2 via the PKA/CREB signaling pathway

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Ginsenoside Rg1 alleviates lipopolysaccharide‑induced neuronal damage by inhibiting NLRP1 inflammasomes in HT22 cells

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TREM2 improves neurological dysfunction and attenuates neuroinflammation, TLR signaling and neuronal apoptosis in the acute phase of intracerebral hemorrhage

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Hydroxysafflor Yellow A Inhibits Aβ1–42-Induced Neuroinflammation by Modulating the Phenotypic Transformation of Microglia via TREM2/TLR4/NF-κB Pathway in BV-2 Cells

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Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro

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TREM2: Keeping Pace With Immune Checkpoint Inhibitors in Cancer Immunotherapy

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The Wheel of p53 Helps to Drive the Immune System

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A natural small molecule aspidosperma-type alkaloid, hecubine, as a new TREM2 activator for alleviating lipopolysaccharide-induced neuroinflammation in vitro and in vivo

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Roles of TREM2 in Alzheimer’s disease

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Microbiota‐Host Immunity Communication in Neurodegenerative Disorders: Bioengineering Challenges for In Vitro Modeling

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Functionalized Cerium Dioxide Nanoparticles with Antioxidative Neuroprotection for Alzheimer’s Disease

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TREM2, Driving the Microglial Polarization, Has a TLR4 Sensitivity Profile After Subarachnoid Hemorrhage

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SOCE-mediated NFAT1–NOX2–NLRP1 inflammasome involves in lipopolysaccharide-induced neuronal damage and Aβ generation

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Neuregulin-1 regulates the conversion of M1/M2 microglia phenotype via ErbB4-dependent inhibition of the NF-κB pathway

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Regulation of TREM2 expression by transcription factor YY1 and its protective effect against Alzheimer’s disease

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EVOO Polyphenols Exert Anti-Inflammatory Effects on the Microglia Cell through TREM2 Signaling Pathway

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Non-canonical pathways associated to Amyloid beta and tau protein dyshomeostasis in Alzheimer’s disease: A narrative review

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MiR-191-5p alleviates microglial cell injury by targeting Map3k12 (mitogen-activated protein kinase kinase kinase 12) to inhibit the MAPK (mitogen-activated protein kinase) signaling pathway in Alzheimer’s disease

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TET2-mutant myeloid cells mitigate Alzheimer’s disease progression via CNS infiltration and enhanced phagocytosis in mice

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MicroRNA‐7 negatively regulates Toll‐like receptor 4 signaling pathway through FAM177A

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Exploring microglia and their phenomenal concatenation of stress responses in neurodegenerative disorders

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The effect of dipeptidyl peptidase IV on disease-associated microglia phenotypic transformation in epilepsy

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Role and Functions of Irisin: A Perspective on Recent Developments and Neurodegenerative Diseases

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Synthetic amyloid beta does not induce a robust transcriptional response in innate immune cell culture systems

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Nutrition in Alzheimer’s disease: a review of an underappreciated pathophysiological mechanism

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Notopterygium incisum roots extract (NRE) alleviates neuroinflammation pathology in Alzheimer’s disease through TLR4-NF-κB pathway

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Gut microbiota metabolites: potential therapeutic targets for Alzheimer’s disease?

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An overview on microglial origin, distribution, and phenotype in Alzheimer's disease

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Triggering receptor expressed on myeloid cells 2 activation downregulates toll‐like receptor 4 expression and ameliorates cognitive impairment in the Aβ1‐42‐induced Alzheimer's disease mouse model

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Recent insights into viral infections as a trigger and accelerator in alzheimer's disease

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The relationship between increased levels of microbiota-derived lipopolysaccharide in obesity and the pathophysiology of neurodegenerative diseases

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Long-lasting effects of lipopolysaccharide on the reproduction and splenic transcriptome of hens and their offspring

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One immune cell to bind them all: platelet contribution to neurodegenerative disease

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Jiedu Yizhi Formula Improves Cognitive Function by Regulating the Gut Dysbiosis and TLR4/NF-κB Signaling Pathway

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Exploring the intricate link between gut microbiota dysbiosis and the aging process: implications for age-related diseases

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