Pathways of Adaptation: Two Case Studies with One Evidence-Based Substance Use Prevention Program Tailored for Indigenous Youth
Open accessAbstract
Indigenous communities often face disproportionate challenges across a variety of health domains, and effective prevention strategies are sorely needed. Unfortunately, evidence is scant regarding what approaches are effective for these communities. A common approach is to take an evidence-based practice or program with documented effectiveness in other populations and implement it with Indigenous populations. While a science of intervention adaptation is emerging, there remains little guidance on processes for adaptation that strategically leverage both existing scientific evidence and Indigenous prevention strategies. In this paper, two case studies illustrate promising practices for adaptation, documenting the approaches of two research teams funded under the National Institutes of Health's initiative to support Intervention Research to Improve Native American Health (IRINAH). These teams worked with distinct Indigenous populations in the USA and Canada to culturally adapt the same prevention program, the Iowa Strengthening Families Program for Parents and Youth 10-14. The approaches of these two teams and the programs that resulted are compared and contrasted, and critical elements of adaptation in partnership with Indigenous communities are discussed.
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Culturally grounded school-based programs report a significant reduction in alcohol use.
“a significant reduction in alcohol use (Ivanich et al., 2020)”
From Bridging Traditions and Prevention: Insights into Implementing and Sustaining Substance Use Programs for Urban AI/AN Communities (2026) · cites this paper as Ivanich et al., 2020
The Case Study 1 adaptations section reports that ten- and eleven-year-olds who had not begun drinking were significantly less likely than controls to drink at one-year follow-up. It also reports little or no effect among adolescents who had already used alcohol. The passage describes a culturally adapted family program, not a school-based program, so the claim omits an important qualifier and misstates the setting. No page number is available in our copy. (LLM, conf=0.87)
Experimental — accuracy not yet measuredThe frameworks did not specify whether modifications were planned (i.e., adaptations) or unplanned, or allow investigators to consider modifications in conjunction with fidelity, a related but distinct implementation outcome.
“The frameworks also did not specify whether modifications were planned (i.e., adaptations) or unplanned (e.g., [2, 4, 27]), or allow investigators to consider modifications in conjunction with fidelity, a related but distinct implementation outcome [1].”
From The FRAME: an expanded framework for reporting adaptations and modifications to evidence-based interventions (2019) · cites this paper as [27]
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Self-citationHong, K., & Shin, J. (2026) · Children · doi:10.3390/children13091193
Beyond the Western Gaze: What Implementation Science Can Learn From Indigenous Knowledge Systems
Kent, A. J., Horsethief, C., Pauly, B., & Shahram, S. (2026) · Health Services Insights · doi:10.1177/11786329261495895
- Authors
- Ivanich, J. D., Mousseau, A. C., Walls, M., Whitbeck, L., & Whitesell, N. R.
- Affiliations
- University of Nebraska–Lincoln (US)
- University of Montana (US)
- University of Minnesota (US)
- Colorado School of Public Health (US)
- Corresponding author
- Whitesell, Nancy Rumbaugh
- Venue
- Prevention Science
- Published
- 2018-06-06
- Volume
- 21
- Issue
- S1
- Pages
- 43-53
- ISSN
- 1389-4986 (ISSN-L)
- 1573-6695
- PMC
- PMC6774906
- OpenAlex
- W2805840363
- Cited by
- 70
- References
- 30
- Citations by year
- 2026: 7 · 2025: 7 · 2024: 7 · 2023: 12 · 2022: 12 · 2021: 12 · 2020: 2 · 2019: 7 · 2018: 3 · 2017: 1
- FWCI
- 6.40
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Prevention Science (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Drug Abuse (R01DA035111, R01DA037177)
- Topics
- Social Sciences › Health › Indigenous Health, Education, and Rights
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
- Keywords
- intervention adaptation, substance use prevention, Indigenous youth, indigenous peoples, community partnerships, Native American health
- MeSH terms
- Adolescent, Canada, Child, Health Promotion, Humans, Indians, North American, United States, Substance-Related Disorders, Organizational Case Studies, Cultural Competency
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