Cited by 21Venous Thromboembolism Diagnosis and ManagementBlood Coagulation and Thrombosis MechanismsMenopause: Health Impacts and Treatments

Estrogen and thrombosis: controversies and common sense

DeLoughery, Thomas G.·2011·Reviews in Endocrine and Metabolic Disorders

Abstract

Soon after the introduction of hormonal oral contraceptive agents reports of thrombotic complications appeared. In the past several decades, large epidemiological studies helped defined these risks for both arterial and venous complications. Clinicians can assess a patient's risk of thrombosis by both composition of the agent and patients' personal risk factors. For women with bleeding disorders these prothrombotic changes can help decrease bleeding complications. There is now also abundant data on future management of patients with estrogen related thrombosis.

Integrity signals

Registry

Crossref · 10.1007/s11154-011-9178-0

Cites

74 of 74 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The increased risk of estrogen-associated thrombosis depends on both the dose and the mode of delivery of the hormone.

    “The increased risk is dependent both on the dose and well as the mode of delivery of the hormone, and studies identify alterations in numerous aspects of the hemostatic and fibrinolytic pathways that contribute to the generation of a prothrombotic milieu.”

    From Estrogen and thrombosis: a bench to bedside review (2020) · cites this paper as [82]

  • Estrogen use is associated with an increased risk of both arterial and venous thrombosis.

    “Estrogen, in the clinical setting is used primarily for contraception and hormone replacement therapy. It has been well established that estrogen increases the risk of both arterial and venous thrombosis.”

    From Estrogen and thrombosis: a bench to bedside review (2020) · cites this paper as [82]

  • Higher doses of estrogen are associated with increased risk of thrombosis.

    “Large meta-analysis in recent years have established clearly that higher doses of estrogen are associated with increased risk of thrombosis (Table I)”

    From Estrogen and thrombosis: a bench to bedside review (2020) · cites this paper as [82]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
DeLoughery, T. G.
Affiliations
Oregon Health & Science University (US)
Corresponding author
DeLoughery, Thomas G.
Venue
Reviews in Endocrine and Metabolic Disorders
Published
2011-05-11
Volume
12
Issue
2
Pages
77-84
ISSN
  • 1389-9155 (ISSN-L)
  • 1573-2606
OpenAlex
W1976352197
Cited by
21
References
74
Citations by year
2026: 1 · 2025: 1 · 2024: 1 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 1 · 2017: 1 · 2016: 2 · 2015: 2 · 2014: 2 · 2013: 1 · 2012: 3
FWCI
0.48
Type
journal article
Language
en
Open access
closed
Locations
  • Reviews in Endocrine and Metabolic Disorders (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Internal Medicine › Venous Thromboembolism Diagnosis and Management
  • Health Sciences › Medicine › Hematology › Blood Coagulation and Thrombosis Mechanisms
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
Keywords
estrogen, thrombosis, oral contraceptives, venous thromboembolism, arterial thrombosis, bleeding disorders, thrombosis risk factors, hormonal contraception
MeSH terms
Adult, Contraceptives, Oral, Hormonal, Estrogens, Female, Humans, Risk Factors, Thrombosis, Hemostatic Disorders, Venous Thrombosis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review