Does Water Temperature Influence the Distribution and Elimination of Perfluorinated Substances in Rainbow trout (Oncorhynchus mykiss)?
Abstract
Perfluorinated and polyfluorinated substances (PFASs) are widely found in freshwater ecosystems because of their resistance to degradation and their ability to accumulate in aquatic organisms. While water temperature controls many physiological processes in fish, knowledge of the effects of this factor on PFAS toxicokinetic is still limited. This study presents experimental results of internal distribution and elimination rates of two perfluorinated acid compounds, namely perfluorooctane sulfonate (PFOS) and perfluorohexane sulfonate (PFHxS) in adult rainbow trout (Oncorhynchus mykiss) exposed to three temperatures. Dietary exposure experiments were conducted at 7 °C, 11 °C, and 19 °C and liver, blood, muscle, brain, and kidney were sampled for analysis. PFOS concentrations were comparable to or exceeded those of PFHxS, while PFHxS was eliminated faster than PFOS, whatever the temperature. Internal distribution changed significantly for both substances when fish were exposed to a range of temperatures from 7 to 19 °C. Indeed, PFOS and PFHxS relative distribution increased in blood, liver, and brain while they decreased in muscle when the water temperature rose. The water temperature variation affected the elimination half-lives, depending on the substances and organs.
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Vidal et al. (2019) reported different elimination half-lives for PFOS and PFHxS in the brains of fish held at different incubation temperatures, determining that half-lives for both compounds were significantly shorter in 7 and 19°C waters than in the optimal temperature range for rainbow trout, at 11°C.
“Vidal et al. (2019) reported different elimination half-lives for PFOS and PFHxS in the brains of fish held at different incubation temperatures, determining that half-lives for both compounds were significantly shorter in 7 and 19°C waters, than in the optimal temperature range for rainbow trout, at 11°C.”
From A Critical Review and Meta-Analysis of Impacts of Per- and Polyfluorinated Substances on the Brain and Behavior (2022) · cites this paper as Vidal et al., 2019
These data highlight the importance of investigating PFAS exposure and neurotoxicity in varying environmental conditions, as these factors could influence PFAS accumulation in the brain, particularly in the wake of climate change.
“These data, which are primarily relevant to PFAS distribution in wildlife, highlight the importance of investigating PFAS exposure and neurotoxicity in varying environmental conditions, as these factors could influence PFAS accumulation in the brain, particularly in the wake of climate change (Borgå et al., 2010; Houde et al., 2011; Vidal et al., 2019).”
From A Critical Review and Meta-Analysis of Impacts of Per- and Polyfluorinated Substances on the Brain and Behavior (2022) · cites this paper as Vidal et al., 2019
Exposure to PFAS in combination with other xenobiotics, or particular environmental conditions, has been shown to have differential impacts on xenobiotic metabolism and distribution to tissues throughout the body.
“Exposure to PFAS in combination with other xenobiotics, or particular environmental conditions, has been shown to have differential impacts on xenobiotic metabolism and distribution to tissues throughout the body (Wang F. et al., 2011; Li Y. et al., 2017; Vidal et al., 2019; Bangma et al., 2022).”
From A Critical Review and Meta-Analysis of Impacts of Per- and Polyfluorinated Substances on the Brain and Behavior (2022) · cites this paper as Vidal et al., 2019
In a 28-day dietary exposure experiment in adult rainbow trout, concentrations of PFOS and PFHxS in the blood, liver, and brain increased with increased water temperature, as did the brain to blood ratio for PFOS.
“For example, Vidal et al. (2019) found that in a 28-day dietary exposure experiment in adult rainbow trout, concentrations of PFOS and PFHxS in the blood, liver, and brain increased with increased water temperature, as did the brain to blood ratio for PFOS.”
From A Critical Review and Meta-Analysis of Impacts of Per- and Polyfluorinated Substances on the Brain and Behavior (2022) · cites this paper as Vidal et al., 2019
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- Authors
- Vidal, A., Lafay, F., Daniele, G., Vulliet, E., Rochard, E., Garric, J., & Babut, M.
- Affiliations
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Lyon 1 Université (FR)
- Corresponding author
- Babut, Marc
- Venue
- Environmental Science and Pollution Research
- Published
- 2019-04-13
- Volume
- 26
- Issue
- 16
- Pages
- 16355-16365
- ISSN
- 0944-1344 (ISSN-L)
- 1614-7499
- OpenAlex
- W2938623697
- Cited by
- 30
- References
- 49
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 5 · 2023: 3 · 2022: 5 · 2021: 3 · 2020: 4 · 2019: 1
- FWCI
- 1.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Environmental Science and Pollution Research (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Irstea Publications et Bases documentaires (Irstea) (submittedVersion)
- Funders
- Région Auvergne-Rhône-Alpes (not available)
- Agence de l'Eau Rhône Méditerranée Corse (not available)
- Topics
- Physical Sciences › Environmental Science › Environmental Chemistry › Per- and polyfluoroalkyl substances research
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
- Keywords
- PFOS, PFHxS, water temperature, rainbow trout, toxicokinetics, internal distribution, elimination half-life, dietary exposure, organ distribution
- MeSH terms
- Dietary Exposure, Animals, Fluorocarbons, Muscles, Sulfonic Acids, Temperature, Tissue Distribution, Water Pollutants, Chemical, Oncorhynchus mykiss, Alkanesulfonic Acids
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