HMG-CoA reductase limits artemisinin biosynthesis and accumulation in Artemisia annua L. plants
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HMGR is a rate-limiting enzyme of the mevalonate pathway and HMGR expression limits artemisinin formation in A. annua.
“HMGR is a rate-limiting enzyme of the mevalonate pathway [24,25], and recently it has been shown that HMGR expression limits artemisinin formation in A. annua [26].”
From Relative expression of genes of terpene metabolism in different tissues of Artemisia annuaL (2011) · cites this paper as [26]
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- Authors
- Ram, M., Khan, M. A., Jha, P., Khan, S., Kiran, U., Ahmad, M. M., Javed, S., & Abdin, M. Z.
- Affiliations
- Jamia Hamdard (IN)
- King Saud University (SA)
- Corresponding author
- Abdin, M. Z.
- Venue
- Acta Physiologiae Plantarum
- Published
- 2010-02-25
- Volume
- 32
- Issue
- 5
- Pages
- 859-866
- ISSN
- 0137-5881 (ISSN-L)
- 1861-1664
- OpenAlex
- W1974348887
- Cited by
- 59
- References
- 30
- Citations by year
- 2026: 2 · 2024: 5 · 2023: 3 · 2022: 4 · 2021: 1 · 2020: 2 · 2019: 2 · 2018: 2 · 2017: 4 · 2016: 6 · 2015: 5 · 2014: 7 · 2013: 7 · 2012: 4
- FWCI
- 2.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Acta Physiologiae Plantarum (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant tissue culture and regeneration
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Sesquiterpenes and Asteraceae Studies
- Keywords
- HMG-CoA reductase, artemisinin biosynthesis, Artemisia annua, lovastatin, mevalonate, fosmidomycin, IAA, gibberellic acid, plant growth regulators, sterol biosynthesis, triterpenoid biosynthesis
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