Engineering Oilseed Plants for a Sustainable, Land‐Based Source of Long Chain Polyunsaturated Fatty Acids
Abstract
Numerous clinical studies have demonstrated the cardiovascular and mental health benefits of including very long chain omega‐3 polyunsaturated fatty acids, namely eicospentaenoic acid (EPA) and docosohexaenoic acid (DHA) in the human diet. Certain fish oils can be a rich source of omega‐3 long chain polyunsaturated fatty acids although processed marine oils are generally undesirable as food ingredients because of the associated objectionable flavors and contaminants that are difficult and cost‐prohibitive to remove. Oilseed plants rich in omega‐3 fatty acids, such as flax and walnut oils, contain only the 18‐carbon omega‐3 polyunsaturated fatty acid alpha‐linolenic acid, which is poorly converted by the human body to EPA and DHA. It is now possible to engineer common omega‐6 rich oilseeds such as soybean and canola to produce EPA and DHA and this has been the focus of a number of academic and industrial research groups. Recent advances and future prospects in the production of EPA and DHA in oilseed crops are discussed here.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Successful experiments improving lipid composition and content in higher plants suggest that improving lipid production in algae is a tenable option to improve biofuel characteristics.
“These successful experiments suggest that improving lipid production in algae is a tenable option to improve biofuel charactieristics.”
From Biofuels from algae: Challenges and potential (2010) · cites this paper as [156]
Cites
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
Funk, C. D. (2001) · Science · doi:10.1126/science.294.5548.1871 · Cited by 3,817 · see citing works
Towards sustainability in world fisheries.
Pauly, D., Christensen, V., Guénette, S., Pitcher, T. J., Sumaila, U. R., Walters, C. J., Watson, R., & Zeller, D. (2002) · Nature · doi:10.1038/nature01017 · Cited by 3,019 · see citing works
Risk of Cardiovascular Events Associated with Selective COX-2 Inhibitors
Mukherjee, D. (2001) · JAMA · doi:10.1001/jama.286.8.954 · Cited by 1,741 · see citing works
Essential fatty acids in health and chronic disease
Simopoulos, A. P. (1999) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/70.3.560s · Cited by 1,684 · see citing works
Metabolism of highly unsaturated n-3 and n-6 fatty acids
Sprecher, H. W. (2000) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(00)00077-9 · Cited by 869 · see citing works
Global Assessment of Organic Contaminants in Farmed Salmon
Hites, R. A., Foran, J. A., Carpenter, D. O., Hamilton, M. C., Knuth, B. A., & Schwager, S. J. (2004) · Science · doi:10.1126/science.1091447 · Cited by 856 · see citing works
Metz, J. G., Roessler, P., Facciotti, D., Levering, C., Dittrich, F., Lassner, M., Valentine, R., Lardizabal, K., Domergue, F., Yamada, A., et al. (2001) · Science · doi:10.1126/science.1059593 · Cited by 760 · see citing works
n−3 Polyunsaturated fatty acids and inflammation: From molecular biology to the clinic
Calder, P. C. (2003) · Lipids · doi:10.1007/s11745-003-1068-y · Cited by 499 · see citing works
Production of very long chain polyunsaturated omega-3 and omega-6 fatty acids in plants
Qi, B., Fraser, T., Mugford, S., Dobson, G., Sayanova, O., Butler, J., Napier, J. A., Stobart, A. K., & Lazarus, C. M. (2004) · Nature Biotechnology · doi:10.1038/nbt972 · Cited by 426 · see citing works
Polyunsaturated fatty acid synthesis: What will they think of next?
Wallis, J. G., Watts, J. L., & Browse, J. (2002) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(02)02168-0 · Cited by 375 · see citing works
V ARIATIONS IN THE B IOSYNTHESIS OF S EED -S TORAGE L IPIDS
Voelker, T. A., & Kinney, A. J. (2001) · Annual Review of Plant Physiology and Plant Molecular Biology · doi:10.1146/annurev.arplant.52.1.335 · Cited by 351 · see citing works
Self-citationAbbadi, A., Domergue, F., Bauer, J., Napier, J. A., Welti, R., Zähringer, U., Cirpus, P., & Heinz, E. (2004) · The Plant Cell · doi:10.1105/tpc.104.026070 · Cited by 322 · see citing works
Stauffer, C. E. (1996) · AACC International eBooks · doi:10.1094/9780913250907 · Cited by 312 · see citing works
Stepwise engineering to produce high yields of very long-chain polyunsaturated fatty acids in plants
Wu, G., Truksa, M., Datla, N., Vrinten, P., Bauer, J., Zank, T., Cirpus, P., Heinz, E., & Qiu, X. (2005) · Nature Biotechnology · doi:10.1038/nbt1107 · Cited by 310 · see citing works
Bell, J. G., McGhee, F., Campbell, P. J., & SARGENT, J. R. (2003) · Aquaculture · doi:10.1016/s0044-8486(02)00462-3 · Cited by 301 · see citing works
Cloning of Higher Plant [omega]-3 Fatty Acid Desaturases
Yadav, N. S., Wierzbicki, A., Aegerter, M., Caster, C., Pérez-Grau, L., Kinney, A. J., Hitz, W. D., Booth, J. R., Jr., Schweiger, B. J., Stecca, K. L., et al. (1993) · PLANT PHYSIOLOGY · doi:10.1104/pp.103.2.467 · Cited by 267 · see citing works
Self-citationQiu, X. K., Hong, H., & MacKenzie, S. L. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m102971200 · Cited by 238 · see citing works
Identification of an animal ω-3 fatty acid desaturase by heterologous expression in Arabidopsis
Spychalla, J. P., Kinney, A. J., & Browse, J. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.4.1142 · Cited by 222 · see citing works
Self-citationSARGENT, J. R. (1997) · British Journal Of Nutrition · doi:10.1079/bjn19970131 · Cited by 196 · see citing works
Eicosapentaenoic acid: biosynthetic routes and the potential for synthesis in transgenic plants
Sayanova, O. V., & Napier, J. A. (2003) · Phytochemistry · doi:10.1016/j.phytochem.2003.10.017 · Cited by 186 · see citing works
PARKER-BARNES, J. M., Das, T., BOBIK, E. G., Leonard, A. E., Thurmond, J. M., Chaung, L.-T., Huang, Y. S., & Mukerji, P. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.15.8284 · Cited by 177 · see citing works
Damude, H. G., Zhang, H., Farrall, L., Ripp, K. G., Tomb, J.-F., Hollerbach, D. H., & Yadav, N. S. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0511079103 · Cited by 173 · see citing works
Self-citationCyclooxygenases, peroxide tone and the allure of fish oil
Smith, W. L. (2005) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2005.02.005 · Cited by 165 · see citing works
Pereira, S. L., Leonard, A. E., Huang, Y. S., Chuang, L., & Mukerji, P. (2004) · Biochemical Journal · doi:10.1042/bj20040970 · Cited by 149 · see citing works
Metabolic engineering of Arabidopsis to produce nutritionally important DHA in seed oil
Robert, S. S., Singh, S. P., Zhou, X., Petrie, J. R., Blackburn, S. I., Mansour, P. M., Nichols, P. D., Liu, Q., & Green, A. G. (2005) · Functional Plant Biology · doi:10.1071/fp05084 · Cited by 147 · see citing works
DEVELOPMENT OF GENETICALLY ENGINEERED SOYBEAN OILS FOR FOOD APPLICATIONS
Kinney, A. J. (1996) · Journal of Food Lipids · doi:10.1111/j.1745-4522.1996.tb00074.x · Cited by 143 · see citing works
Self-citationPlant Biotechnology and Transgenic Plants
(2002) · CRC Press eBooks · doi:10.1201/9780203910849 · Cited by 139 · see citing works
Fatty acids and the immune system: from basic science to clinical applications
Yaqoob, P. (2004) · Proceedings of The Nutrition Society · doi:10.1079/pns2003328 · Cited by 139 · see citing works
Iribarren, C., Markovitz, J. H., Jacobs, D. R., Schreiner, P. J., Daviglus, M. L., & Hibbeln, J. R. (2003) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1601739 · Cited by 125 · see citing works
A hypothesis on the development of acute myocardial infarction in Greenlanders
Dyerberg, J., & Bang, H. O. (1982) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365518209168395 · Cited by 116 · see citing works
Designer oils: the high oleic acid soybean
Kinney, A. J., & Knowlton, S. (1998) · Springer eBooks · doi:10.1007/978-1-4615-5815-6_10 · Cited by 105 · see citing works
Self-citationJacobs, M. N., Covaci, A., Gheorghe, A., & Schepens, P. (2004) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf035310q · Cited by 105 · see citing works
A hypothesis on the development of acute myocardial infarction in Greenlanders
Dyerberg, J., & Bang, H. O. (1982) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/00365518209168395 · Cited by 100 · see citing works
The role of long-chain polyunsaturated fatty acids in infant cognitive development
Willatts, P., & Forsyth, J. S. (2000) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1054/plef.2000.0198 · Cited by 97 · see citing works
LANDS, W. E. M. (2005) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1323.028 · Cited by 93 · see citing works
Constructing Polyketides: From Collie to Combinatorial Biosynthesis
Bentley, R., & Bennett, J. W. (1999) · Annual Review of Microbiology · doi:10.1146/annurev.micro.53.1.411 · Cited by 86 · see citing works
A novel omega3-fatty acid desaturase involved in the biosynthesis of eicosapentaenoic acid
Pereira, S. L., Huang, Y. S., BOBIK, E. G., Kinney, A. J., Stecca, K. L., Packer, J. C. L., & Mukerji, P. (2004) · Biochemical Journal · doi:10.1042/bj20031319 · Cited by 84 · see citing works
Self-citationSakuradani, E., Abe, T., Iguchi, K., & Shimizu, S. (2004) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-004-1760-x · Cited by 84 · see citing works
Increasing homicide rates and linoleic acid consumption among five western countries, 1961–2000
Hibbeln, J. R., Nieminen, L. R. G., & Lands, W. E. M. (2004) · Lipids · doi:10.1007/s11745-004-1349-5 · Cited by 74 · see citing works
The Elimination of Trans Fats from Spreads: How Science Helped to Turn an Industry Arounda
Korver, O., & Katan, M. (2006) · Nutrition Reviews · doi:10.1111/j.1753-4887.2006.tb00210.x · Cited by 68 · see citing works
Chen, R., Matsui, K., Ogawa, M., Oe, M., Ochiai, M., Kawashima, H., Sakuradani, E., Shimizu, S., Ishimoto, ., Hayashi, M., et al. (2005) · Plant Science · doi:10.1016/j.plantsci.2005.09.006 · Cited by 57 · see citing works
Pereira, S. L., Leonard, A. E., Huang, Y. S., Chuang, L., & Mukerji, P. (2004) · NCHU Institutional Repository CRIS · Cited by 55 · see citing works
Genetic Modification in the Food Industry
Roller, S., & Harlander, S. (1998) · Springer eBooks · doi:10.1007/978-1-4615-5815-6 · Cited by 51 · see citing works
Saccharomyces kluyveri FAD3 encodes an ω3 fatty acid desaturase
Oura, T., & Kajiwara, S. (2004) · Microbiology · doi:10.1099/mic.0.27049-0 · Cited by 50 · see citing works
The production of long chain polyunsaturated fatty acids in transgenic plants by reverse-engineering
Napier, J. A., Beaudoin, F., Michaelson, L. V., & Sayanova, O. (2004) · Biochimie · doi:10.1016/j.biochi.2004.09.020 · Cited by 36 · see citing works
Progress toward the production of long‐chain polyunsaturated fatty acids in transgenic plants
Napier, J. A., Sayanova, O. V., Qi, B., & Lazarus, C. M. (2004) · Lipids · doi:10.1007/s11745-004-1332-1 · Cited by 35 · see citing works
Stoll, A. L., Damico, K. E., Daly, B. P., Severus, W. E., & Marangell, L. B. (2000) · KARGER eBooks · doi:10.1159/000059745 · Cited by 21 · see citing works
19th International Symposium on Plant Lipids
(2010) · Nutrition & Food Science · doi:10.1108/nfs.2010.01740bac.005 · Cited by 9 · see citing works
Evolutionary Aspects of Diet, the Omega-6/Omega-3 Ratio, and Gene Expression
Simopoulos, A. P. (2006) · CRC Press eBooks · doi:10.1201/9781420005905.ch10 · Cited by 5 · see citing works
Transgenic Plants as Sources of Modified Oils
Coughlan, S., & Kinney, A. J. (2002) · CRC Press eBooks · doi:10.1201/9780203910849.ch13 · Cited by 3 · see citing works
Self-citationTransgenic Plants as Sources of Modified Oils
Kinney, A. J. (2002) · doi:10.1201/9780203910849-18 · Cited by 2 · see citing works
Self-citation
Flagged first, then by citations
1 of the 52 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Biofuels from algae: Challenges and potential
Hannon, M., Gimpel, J., Tran, M., Rasala, B., & Mayfield, S. (2010) · Biofuels · doi:10.4155/bfs.10.44 · Cited by 813 · see citing works
Soybean Oil: Genetic Approaches for Modification of Functionality and Total Content
Clemente, T. E., & Cahoon, E. B. (2009) · PLANT PHYSIOLOGY · doi:10.1104/pp.109.146282 · Cited by 615 · see citing works
Stark, K. D., Van Elswyk, M. E., Higgins, M. R., Weatherford, C. A., & Salem, N. (2016) · Progress in Lipid Research · doi:10.1016/j.plipres.2016.05.001 · Cited by 519 · see citing works
Thraustochytrid Marine Protists: Production of PUFAs and Other Emerging Technologies
Raghukumar, S. (2008) · Marine Biotechnology · doi:10.1007/s10126-008-9135-4 · Cited by 269 · see citing works
Production of EPA and DHA in aquatic ecosystems and their transfer to the land
Gladyshev, M. I., Sushchik, N. N., & Makhutova, O. N. (2013) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2013.03.002 · Cited by 255 · see citing works
The role of light in soybean seed filling metabolism
Allen, D. K., Ohlrogge, J. B., & Shachar‐Hill, Y. (2008) · The Plant Journal · doi:10.1111/j.1365-313x.2008.03771.x · Cited by 225 · see citing works
Odd-numbered very-long-chain fatty acids from the microbial, animal and plant kingdoms
Řezanka, T., & Sigler, K. (2009) · Progress in Lipid Research · doi:10.1016/j.plipres.2009.03.003 · Cited by 214 · see citing works
n -3 Oil sources for use in aquaculture – alternatives to the unsustainable harvest of wild fish
Miller, M. R., Nichols, P. D., & Carter, C. G. (2008) · Nutrition Research Reviews · doi:10.1017/s0954422408102414 · Cited by 184 · see citing works
Gladyshev, M. I., Arts, M. T., & Сущик, Н. Н. (2009) · Springer eBooks · doi:10.1007/978-0-387-89366-2_8 · Cited by 155 · see citing works
Biological Role of Unsaturated Fatty Acid Desaturases in Health and Disease
Czumaj, A., & Śledziński, T. (2020) · Nutrients · doi:10.3390/nu12020356 · Cited by 150 · see citing works
Vegetable Oil: Nutritional and Industrial Perspective
KUMAR, A. T., Sharma, A., & Upadhyaya, K. C. (2016) · Current Genomics · doi:10.2174/1389202917666160202220107 · Cited by 141 · see citing works
Wu, S., & Chappell, J. (2008) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2008.02.007 · Cited by 133 · see citing works
The role of transgenic crops in sustainable development
Park, J. R., MCFARLANE, I. D., Phipps, R. H., & Ceddia, G. (2010) · Plant Biotechnology Journal · doi:10.1111/j.1467-7652.2010.00565.x · Cited by 128 · see citing works
Buiatti, M., Christou, P., & Pastore, G. (2012) · Genes & Nutrition · doi:10.1007/s12263-012-0316-4 · Cited by 110 · see citing works
Pilecky, M., Závorka, L., Arts, M. T., & Kainz, M. J. (2021) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12747 · Cited by 104 · see citing works
Single Cell Oils for the 21st Century
Ratledge, C. (2010) · Elsevier eBooks · doi:10.1016/b978-1-893997-73-8.50005-0 · Cited by 105 · see citing works
Komprda, T. (2011) · Journal of Functional Foods · doi:10.1016/j.jff.2011.10.008 · Cited by 103 · see citing works
Sustainable alternatives to dietary fish oil in tropical fish aquaculture
Alhazzaa, R., Nichols, P. D., & Carter, C. G. (2018) · Reviews in Aquaculture · doi:10.1111/raq.12287 · Cited by 103 · see citing works
Elevated Production of Docosahexaenoic Acid in Females: Potential Molecular Mechanisms
Kitson, A. P., Stroud, C. K., & Stark, K. D. (2010) · Lipids · doi:10.1007/s11745-010-3391-6 · Cited by 104 · see citing works
Inventory of Fatty Acid Desaturases in the Pennate Diatom Phaeodactylum tricornutum
Dolch, L.-J., & Maréchal, É. (2015) · Marine Drugs · doi:10.3390/md13031317 · Cited by 91 · see citing works
Usher, S. L., Haslam, R. P., Ruiz‐López, N., Sayanova, O. V., & Napier, J. A. (2015) · Metabolic Engineering Communications · doi:10.1016/j.meteno.2015.04.002 · Cited by 88 · see citing works
Nykiforuk, C. L., Shewmaker, C. K., Harry, I. S., Yurchenko, O. P., Zhang, M., Reed, C. C., Oinam, G. S., Zaplachinski, S., Fidantsef, A. L., Boothe, J. G., et al. (2011) · Transgenic Research · doi:10.1007/s11248-011-9543-5 · Cited by 70 · see citing works
Breeding for sustainable oilseed crop yield and quality in a changing climate
Attia, Z., Pogoda, C. S., Reinert, S., Kane, N. C., & Hulke, B. S. (2021) · Theoretical and Applied Genetics · doi:10.1007/s00122-021-03770-w · Cited by 64 · see citing works
Filamentous Fungi for Production of Food Additives and Processing Aids
Archer, D. B., Connerton, I. F., & MacKenzie, D. A. (2008) · Advances in biochemical engineering, biotechnology · doi:10.1007/10_2007_094 · Cited by 62 · see citing works
Rogalski, M., & Carrer, H. (2011) · Plant Biotechnology Journal · doi:10.1111/j.1467-7652.2011.00621.x · Cited by 53 · see citing works
Hồng, Đ. D., Anh, H. T. L., & Thu, N. T. H. (2011) · Journal of Phycology · doi:10.1111/j.1529-8817.2011.01012.x · Cited by 42 · see citing works
Li, Z., Moon, B. P., Xing, A., Liu, Z.-B., McCardell, R. P., Damude, H. G., & Falco, S. C. (2010) · PLANT PHYSIOLOGY · doi:10.1104/pp.110.160093 · Cited by 42 · see citing works
Self-citationKitessa, S. M., & Young, P. (2008) · British Journal Of Nutrition · doi:10.1017/s0007114508030742 · Cited by 38 · see citing works
Essential Polyunsaturated Fatty Acids and their Dietary Sources for Man
Gladyshev, M. I. (2012) · Journal of Siberian Federal University Biology · doi:10.17516/1997-1389-0128 · Cited by 36 · see citing works
Gibbs, R. A., Rymer, C., & Givens, D. I. (2009) · Proceedings of The Nutrition Society · doi:10.1017/s0029665109991716 · Cited by 35 · see citing works
Recommended Intake of Fish and Fish Oils Worldwide
Richter, C. K., Skulas‐Ray, A. C., & Kris‐Etherton, P. M. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802844-5.00003-8 · Cited by 35 · see citing works
Chung, O. K., Ohm, J., Ram, M., & Howitt, C. A. (2009) · AACC International eBooks · doi:10.1094/9781891127557.010 · Cited by 34 · see citing works
Briend, A., Dewey, K. G., & Reinhart, G. A. (2011) · Maternal and Child Nutrition · doi:10.1111/j.1740-8709.2011.00305.x · Cited by 33 · see citing works
Jiao, J., & Zhang, Y. (2013) · Chemical Reviews · doi:10.1021/cr300007p · Cited by 32 · see citing works
Caamaño, E., Loperena, L., Hinzpeter, I., Pradel, P., Gordillo, F., Corsini, G., Tello, M., Lavin, P. L., & González, A. (2017) · Brazilian Journal of Microbiology · doi:10.1016/j.bjm.2017.01.011 · Cited by 32 · see citing works
Botelho, P. B., Mariano, K. D. R., Rogero, M. M., & de Castro, I. A. (2013) · Lipids in Health and Disease · doi:10.1186/1476-511x-12-38 · Cited by 30 · see citing works
Bhunia, R. K., Chakraborty, A., Kaur, R., Maiti, M. K., & Sen, S. K. (2015) · Plant Cell Reports · doi:10.1007/s00299-015-1880-z · Cited by 29 · see citing works
Dalal, J., Yalamanchili, R., Hovary, C. L., Ji, M., Rodriguez-Welsh, M., Aslett, D. M., Ganapathy, S., Grunden, A. M., Sederoff, H. W., & Rongda Qu, A. (2015) · Plasmid · doi:10.1016/j.plasmid.2015.06.003 · Cited by 28 · see citing works
Lipids: Absorption and Transport
Lichtenstein, A. H., & Jones, P. J. H. (2012) · doi:10.1002/9781119946045.ch9 · Cited by 23 · see citing works
Kitessa, S. M., & Young, P. (2011) · Animal Feed Science and Technology · doi:10.1016/j.anifeedsci.2011.08.007 · Cited by 19 · see citing works
Ganesh, V., & HETTIARACHCHY, N. S. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2013.765383 · Cited by 20 · see citing works
Terrestrial Sources of Polyunsaturated Fatty Acids for Aquaculture
Gladyshev, M. I. (2021) · Journal of Ichthyology · doi:10.1134/s0032945221030036 · Cited by 18 · see citing works
Biosynthesis and Biotechnology of Seed Lipids Including Sterols, Carotenoids and Tocochromanols
Meyer, K., & Kinney, A. J. (2009) · Advances in photosynthesis and respiration · doi:10.1007/978-90-481-2863-1_19 · Cited by 17 · see citing works
Self-citationKlubicová, K., Berčák, M., Danchenko, M., Škultéty, Ľ., Rashydov, N. M., Berezhna, V. V., Miernyk, J. A., & Hajdúch, M. (2010) · Phytochemistry · doi:10.1016/j.phytochem.2010.11.010 · Cited by 16 · see citing works
Gunatilaka, A. L. (2012) · doi:10.1002/9781118391815.ch1 · Cited by 14 · see citing works
Chen, L., Hu, Q., Li, G., Zhang, L., Qin, L., Zuo, H., & Xu, G. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2021.743852 · Cited by 13 · see citing works
Anbu, P., Kim, D.-U., Jeh, E.-J., Jeong, Y., & Hur, B. (2007) · Biotechnology and Bioprocess Engineering · doi:10.1007/bf02931091 · Cited by 13 · see citing works
Pharmacological properties of Flax seeds: A Review
Halligudi, N. N. (2012) · Cited by 12 · see citing works
New Alternative n-3 Long-Chain Polyunsaturated Fatty Acid-Rich Oil Sources
Miller, M. R., Nichols, P. D., & Carter, C. G. (2010) · CRC Press eBooks · doi:10.1201/9781439808634-c10 · Cited by 11 · see citing works
Makhutova, O. N., & Gladyshev, M. I. (2020) · Российский физиологический журнал им И М Сеченова · doi:10.31857/s0869813920050040 · Cited by 10 · see citing works
Danchenko, M., Klubicová, K., Krivohizha, M. V., Berezhna, V. V., Sakada, V. I., Hajdúch, M., & Rashydov, N. M. (2016) · Cytology and Genetics · doi:10.3103/s0095452716060050 · Cited by 8 · see citing works
Natural Products in Plants: Chemical Diversity
Gunatilaka, A. L. (2008) · Wiley Encyclopedia of Chemical Biology · doi:10.1002/9780470048672.wecb163 · Cited by 8 · see citing works
Genetic Engineering Approaches for Trait Development in Brassica Oilseed Species
Weselake, R. J. (2011) · Elsevier eBooks · doi:10.1016/b978-0-9818936-5-5.50007-3 · Cited by 7 · see citing works
Utilizing the bioactive contents of specialty oils and fats
Kerrihard, A. L., & Pegg, R. B. (2015) · Elsevier eBooks · doi:10.1016/b978-1-78242-376-8.00013-2 · Cited by 5 · see citing works
Agranoff, B. W. (2008) · Gastronomica The Journal of Food and Culture · doi:10.1525/gfc.2008.8.3.79 · Cited by 4 · see citing works
Shi, T., Yu, A., Li, M., Zhang, M., Xing, L., & Li, M. (2013) · Biotechnology Letters · doi:10.1007/s10529-013-1194-6 · Cited by 4 · see citing works
Li, M., Ou, X., Yang, X., Guo, D., Qian, X., Xing, L., & Li, M. (2012) · Biotechnology and Bioprocess Engineering · doi:10.1007/s12257-011-0037-3 · Cited by 4 · see citing works
Applications of Omega-3 Fats in Foods
Hernandez, E. M., & de Jong, L. (2011) · Elsevier eBooks · doi:10.1016/b978-1-893997-82-0.50010-4 · Cited by 4 · see citing works
Miller, M. R. (2007) · Cited by 4 · see citing works
Bridging Genomic and Classical Breeding Approaches for Improving Crop Productivity
Rahman, M., Shaheen, T., Ashraf, M., & Zafar, Y. (2012) · Springer eBooks · doi:10.1007/978-94-007-4116-4_2 · Cited by 3 · see citing works
Thapa, M., Majumdar, T. D., Ghosh, C. K., Mukherjee, A., & Biswas, P. K. (2021) · ACS Food Science & Technology · doi:10.1021/acsfoodscitech.1c00116 · Cited by 3 · see citing works
Konstantinov, D. K., Menzorov, A. G., Кривенко, О. В., & Doroshkov, A. V. (2022) · PeerJ · doi:10.7717/peerj.12737 · Cited by 3 · see citing works
Kinney, A. J. (2016) · Encyclopedia of Applied Plant Sciences · doi:10.1016/b978-0-12-394807-6.00224-0 · Cited by 3 · see citing works
Self-citationSainger, M., Sainger, P. A., Chaudhary, D., Jaiwal, R., Singh, R. P., Dhankher, O. P., & Jaiwal, P. K. (2015) · Springer eBooks · doi:10.1007/978-81-322-2662-8_11 · Cited by 3 · see citing works
New fatty acids, oxylipins and volatiles in microalgae
Lang, I. (2007) · doi:10.53846/goediss-243 · Cited by 7 · see citing works
Roscoe, T. J., Domergue, F., Devic, M., & Lessire, R. (2012) · Springer eBooks · doi:10.1007/978-94-007-4749-4_25 · Cited by 1 · see citing works
Newton, R. (2014) · Cited by 1 · see citing works
Patterson, T. G. (2015) · doi:10.1002/9781118961117.ch6 · Cited by 1 · see citing works
Improving Oils and Oilseeds Through Crop Genetics
Knowlton, S. (2020) · Bailey's Industrial Oil and Fat Products · doi:10.1002/047167849x.bio092 · Cited by 1 · see citing works
Hernandez, E. M. (2015) · doi:10.1002/9781118961117.ch11
Chen, Y. (2012) · University Library - University of Saskatchewan (University of Saskatchewan)
Molecular biomechanics of seed germination in Arabidopsis thaliana and Lepidium sativum
Ghita, M. (2014) · Nottingham ePrints (University of Nottingham)
DHA Principle Applied to Molecular Farming
(2009) · CRC Press eBooks · doi:10.1201/9781439813003-c18
Omega 3, 6, 9 Enhanced Goat Meat (Omega-Chevon) from Flaxseed and Canola Fed Meat Goats
Corley, M. M., Bhardwaj, H. L., Abraha-Eyob, Z., Hamama, A. A., Stringfield, C., & Corley, R. N. (2017) · Applied Science and Innovative Research · doi:10.22158/asir.v1n1p17
The effect of dietary omega-3 fatty acids with specific reference to Echium seed oil on pork quality
Wyngaard, V., & Elizabeth, B. (2019)
Metabolic engineering of green chemical biosynthesis
Das, S., & Prakash, B. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-95590-4.00011-4
Engineering Long-Chain Omega-3 Fatty Acids Pathway in Oleaginous Microbes and Oilseeds
Salunke, G. R., & Kadoo, N. Y. (2025) · Springer eBooks · doi:10.1007/978-3-031-84200-9_22
- Authors
- Damude, H. G., & Kinney, A. J.
- Affiliations
- DuPont (United States) (US)
- Corresponding author
- Kinney, Anthony J.
- Venue
- Lipids
- Publisher
- Wiley
- Published
- 2007-03-14
- Volume
- 42
- Issue
- 3
- Pages
- 179-85
- ISSN
- 0024-4201 (ISSN-L)
- 1558-9307
- OpenAlex
- W2037129260
- Cited by
- 78
- References
- 52
- Citations by year
- 2025: 1 · 2023: 1 · 2022: 1 · 2021: 5 · 2020: 3 · 2019: 1 · 2018: 1 · 2017: 2 · 2016: 5 · 2015: 9 · 2014: 2 · 2013: 4 · 2012: 10
- FWCI
- 0.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Lipids (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Keywords
- omega-3 fatty acids, eicosapentaenoic acid, docosahexaenoic acid, long-chain polyunsaturated fatty acids, oilseed crops, soybean, canola, alpha-linolenic acid, linseed oil, walnut oil, cardiovascular health, sustainable food sources
- MeSH terms
- Fatty Acids, Unsaturated, Genetic Engineering, Humans, Plant Oils, Plants, Genetically Modified
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review