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Cited by 30Probiotics and Fermented FoodsNosocomial Infections in ICUClinical Nutrition and Gastroenterology

The DOI matches its Crossref record; 85 of the 85 references it cites were found in a registry or an index.

Bugs or Drugs: Are Probiotics Safe for Use in the Critically Ill?

Urben, Lindsay M., Wiedmar, Jennifer, Boettcher, Erica, Cavallazzi, Rodrigo, Martindale, Robert G., McClave, Stephen A.·2014·Current Gastroenterology Reports
DOI 10.1007/s11894-014-0388-y
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Abstract

Probiotics are living microorganisms which have demonstrated many benefits in prevention, mitigation, and treatment of various disease states in critically ill populations. These diseases include antibiotic-associated diarrhea, Clostridium difficile diarrhea, ventilator-associated pneumonia, clearance of vancomycin-resistant enterococci from the GI tract, pancreatitis, liver transplant, major abdominal surgery, and trauma. However, their use has been severely limited due to a variety of factors including a general naïveté within the physician community, lack of regulation, and safety concerns. This article focuses on uses for probiotics in prevention and treatment, addresses current concerns regarding their use as well as proposing a protocol for safe use of probiotics in the critically ill patient.

Overview

Integrity signals

Registry

Crossref · 10.1007/s11894-014-0388-y

Cites

85 of 85 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Individual differences in microbiomes further complicate the problem of probiotic efficacy and safety.

    “Individual differences in microbiomes further complicate the problem [87,139].”

    From Current Concepts in Probiotic Safety and Efficacy (2026) · cites this paper as [139]

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 1

  1. Wu XG, Zhang QC. Adjuvant therapy for probiotics in patients with severe acute pancreatitis with hepatic lesion: an analysis of 27 cases. Clin Med. 2009;29:51–2.

Cited by

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Related

Metadata

Authors
Urben, L. M., Wiedmar, J., Boettcher, E., Cavallazzi, R., Martindale, R. G., & McClave, S. A.
Affiliations
  • University of Louisville Hospital (US)
  • Kaiser Permanente (US)
  • University of Louisville (US)
  • Oregon Health & Science University (US)
Corresponding author
McClave, Stephen A.
ORCID
Venue
Current Gastroenterology Reports
Publisher
Springer Science and Business Media LLC
Published
2014-07
Volume
16
Issue
7
Pages
388-388
ISSN
  • 1522-8037 (ISSN-L)
  • 1534-312X
DOI
10.1007/s11894-014-0388-y
OpenAlex
W1976708148
Cited by
29
References
85
Citations by year
2026: 1 · 2025: 2 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 2 · 2020: 3 · 2019: 1 · 2018: 3 · 2017: 8 · 2016: 4 · 2015: 2
FWCI
0.58
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Current Gastroenterology Reports (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Nosocomial Infections in ICU
  • Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
Keywords
probiotics, critically ill patients, probiotic safety, antibiotic-associated diarrhea, Clostridium difficile-associated diarrhea, ventilator-associated pneumonia, vancomycin-resistant enterococci, pancreatitis, liver transplantation, major abdominal surgery, trauma (physical injury), probiotic regulation
MeSH terms
Abdomen, Acute Disease, Anti-Bacterial Agents, Clinical Protocols, Diarrhea, Humans, Opportunistic Infections, Pancreatitis, Liver Transplantation, Critical Illness, Probiotics, Perioperative Care, Pneumonia, Ventilator-Associated

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

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