Role of Sleep Disturbance in Chronic Hepatitis C Infection
Open accessAbstract
Chronic infection with the hepatitis C virus (CHC) is associated with physical and mental symptoms including fatigue and depression that adversely affect quality of life. A related complaint, sleep disturbance, has received little attention in the literature, with the exception of sleep changes noted in cirrhosis and end-stage liver disease. We present an overview of studies indicating sleep problems in patients with CHC, with about 60% to 65% of individuals reporting such complaints. Evidence suggests that impairments in sleep quality exist independent of antiviral therapy with interferon-alpha and prior to advanced stages of liver disease. Further investigation of sleep disturbance in CHC patients with a mild stage of liver disease may provide important information on disease course as well as allow additional opportunities for patient support.
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Sleep disturbance is a common complaint among patients with HCV and can affect mental and physical health.
“Sleep disturbance is a common complaint among patients with HCV and can affect mental and physical health [34].”
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- Authors
- Carlson, M. D., Hilsabeck, R. C., Barakat, F., & Perry, W.
- Affiliations
- University of California San Diego (US)
- University of California System (US)
- Corresponding author
- Carlson, Meghan D.
- Venue
- Current Hepatitis Reports
- Published
- 2010-02
- Volume
- 9
- Issue
- 1
- Pages
- 25-29
- ISSN
- 1540-3416 (ISSN-L)
- 1541-0706
- PMC
- PMC2829649
- OpenAlex
- W2050702217
- Cited by
- 38
- References
- 34
- Citations by year
- 2024: 2 · 2022: 1 · 2021: 4 · 2020: 3 · 2019: 6 · 2018: 3 · 2017: 5 · 2016: 1 · 2015: 2 · 2014: 4 · 2013: 4
- FWCI
- 2.93
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc
- Locations
- Current Hepatology Reports (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Hepatology › Hepatitis C virus research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Keywords
- hepatitis C, chronic hepatitis C, sleep disorders, sleep quality, fatigue, depression, quality of life, interferon-alpha
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