Bile Salt Hydrolase (Bsh) Activity Screening of Lactobacilli: In Vitro Selection of Indigenous Lactobacillus Strains with Potential Bile Salt Hydrolysing and Cholesterol-Lowering Ability

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

Lowry, O. H., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 316,394

Guidelines for the evaluation of probiotics in food

Who, F. (2002) · Medical Entomology and Zoology · Cited by 1,843

The interaction between bacteria and bile

Begley, M., Gahan, C. G. M., & Hill, C. (2004) · FEMS Microbiology Reviews · doi:10.1016/j.femsre.2004.09.003 · Cited by 1,776

Bile Salt Hydrolase Activity in Probiotics

Begley, M., Hill, C., & Gahan, C. G. M. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.72.3.1729-1738.2006 · Cited by 1,187

Determination of cholesterol using o-phthalaldehyde

Rudel, L. L., & Morris, M. D. (1973) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)36896-6 · Cited by 1,044

Assimilation of cholesterol by Lactobacillus acidophilus

Gilliland, S. E., Nelson, C. R., & Maxwell, C. V. (1985) · Applied and Environmental Microbiology · doi:10.1128/aem.49.2.377-381.1985 · Cited by 652

Effects of Consumption of Probiotics and Prebiotics on Serum Lipid Levels in Humans

Pereira, D. I. A., & Gibson, G. R. (2002) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409230290771519 · Cited by 450

Characterization of Lactobacillus plantarum PH04, a potential probiotic bacterium with cholesterol-lowering effects

Nguyen, T. D. T., Kang, J.-H., & Lee, M. S. (2006) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2006.08.015 · Cited by 376

Listeria monocytogenes bile salt hydrolase is a PrfA‐regulated virulence factor involved in the intestinal and hepatic phases of listeriosis

Dussurget, O., Cabanes, D., Dehoux, P., Lecuit, M., Buchrieser, C., Glaser, P., & Cossart, P. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.03080.x · Cited by 356

Significance of bile salt hydrolytic activities of lactobacilli

Smet, I. D., Hoorde, L. V., Woestyne, M. V., Christiaens, H., & Verstraete, W. (1995) · Journal of Applied Bacteriology · doi:10.1111/j.1365-2672.1995.tb03140.x · Cited by 307

Factors to Consider When Selecting a Culture of Lactobacillus acidophilus as a Dietary Adjunct to Produce a Hypocholesterolemic Effect in Humans

Gilliland, S. E., & Walker, D. K. (1990) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(90)78747-4 · Cited by 307

Bile Salt Hydrolase of Bifidobacterium longum —Biochemical and Genetic Characterization

Tanaka, H., Hashiba, H., Kok, J., & Mierau, I. (2000) · Applied and Environmental Microbiology · doi:10.1128/aem.66.6.2502-2512.2000 · Cited by 285

Screening of Lactic Acid Bacteria for Bile Salt Hydrolase Activity

Tanaka, H., Doesburg, K. K., Iwasaki, T., & Mierau, I. (1999) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(99)75506-2 · Cited by 283

Deconjugation of bile acids by intestinal lactobacilli

Gilliland, S. E., & Speck, M. L. (1977) · Applied and Environmental Microbiology · doi:10.1128/aem.33.1.15-18.1977 · Cited by 252

Characterisation and selection of probiotic lactobacilli for a preliminary minipig feeding trial and their effect on serum cholesterol levels, faeces pH and faeces moisture content

du Toit, M., Franz, C. M. A. P., Dicks, L. M. T., Schillinger, U., Haberer, P., Warlies, B., Ahrens, F., & Holzapfel, W. H. (1998) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(98)00024-5 · Cited by 251

Bile salt deconjugation ability, bile salt hydrolase activity and cholesterol co-precipitation ability of lactobacilli strains

Liong, M., & Shah, N. P. (2004) · International Dairy Journal · doi:10.1016/j.idairyj.2004.08.007 · Cited by 230

Bile Salt Hydrolase Activity and Resistance to Toxicity of Conjugated Bile Salts Are Unrelated Properties in Lactobacilli

Moser, S. A., & Savage, D. C. (2001) · Applied and Environmental Microbiology · doi:10.1128/aem.67.8.3476-3480.2001 · Cited by 222

Functional Analysis of Four Bile Salt Hydrolase and Penicillin Acylase Family Members in Lactobacillus plantarum WCFS1

Lambert, J. M., Bongers, R. S., de Vos, W. M., & Kleerebezem, M. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.00137-08 · Cited by 220

An In Vitro Study of the Probiotic Potential of a Bile-Salt-Hydrolyzing Lactobacillus fermentum Strain, and Determination of Its Cholesterol-Lowering Properties

Pereira, D. I. A., McCartney, A. L., & Gibson, G. R. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.8.4743-4752.2003 · Cited by 215

Cholesterol lowering in pigs through enhanced bacterial bile salt hydrolase activity

Smet, I. D., Boever, P. D., & Verstraete, W. (1998) · British Journal Of Nutrition · doi:10.1079/bjn19980030 · Cited by 182

Probiotic Bile Salt Hydrolase: Current Developments and Perspectives

Patel, A. K., Singhania, R. R., Pandey, A., & Chincholkar, S. B. (2009) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-009-8738-1 · Cited by 171

Hypocholesterolaemic effect of dietary inclusion of two putative probiotic bile salt hydrolase-producing Lactobacillus plantarum strains in Sprague–Dawley rats

Kumar, R., Grover, S., & Batish, V. K. (2010) · British Journal Of Nutrition · doi:10.1017/s0007114510003740 · Cited by 158

Identification and Characterization of a Bile Acid 7α-Dehydroxylation Operon in Clostridium sp. Strain TO-931, a Highly Active 7α-Dehydroxylating Strain Isolated from Human Feces

Wells, J. E., & Hylemon, P. B. (2000) · Applied and Environmental Microbiology · doi:10.1128/aem.66.3.1107-1113.2000 · Cited by 154

Bile Salt Deconjugation and Cholesterol Removal from Media by Lactobacillus casei

Brashears, M. M., Gilliland, S. E., & Buck, L. M. (1998) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(98)75785-6 · Cited by 143

Effect of dietary inclusion of Lactobacillus acidophilus ATCC 43121 on cholesterol metabolism in rats.

Park, Y. H., Kim, J. G., Shin, Y. W., Kim, S. H., & Whang, K. Y. (2007) · PubMed · Cited by 141

Cloning and characterization of a conjugated bile acid hydrolase gene from Clostridium perfringens

Coleman, J. P., & Hudson, L. L. (1995) · Applied and Environmental Microbiology · doi:10.1128/aem.61.7.2514-2520.1995 · Cited by 140

Purification and Characterization of Three Different Types of Bile Salt Hydrolases from Bifidobacterium Strains

Kim, G.-B., Yi, S.-H., & Lee, B. H. (2004) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(04)73164-1 · Cited by 135

Bile Salt Hydrolase Activity of Enterococci Isolated from Food: Screening and Quantitative Determination

Franz, C. M. A. P., Specht, I., Haberer, P., & Holzapfel, W. H. (2001) · Journal of Food Protection · doi:10.4315/0362-028x-64.5.725 · Cited by 118

Host‐pathogens cross‐talk. Indigenous bacteria and probiotics also play the game

Freitas, M., Tavan, E., Cayuela, C., Diop, L., Sapin, C., & Trugnan, G. (2003) · Biology of the Cell · doi:10.1016/j.biolcel.2003.08.004 · Cited by 99

Isolation and characterization of a Lactobacillus amylovorus mutant depleted in conjugated bile salt hydrolase activity: relation between activity and bile salt resistance

Grill, J.-P., Cayuela, C., Antoine, J., & Schneider, F. (2000) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2000.01147.x · Cited by 88

Purification and Characterization of a New Hydrolase for Conjugated Bile Acids, Chenodeoxycholyltaurine Hydrolase, from Bacteroides vulgatus

Kawamoto, K., Horibe, I., & Uchida, K. (1989) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a122962 · Cited by 83

Hypocholesteremic effect of bile salt hydrolase from Lactobacillus buchneri ATCC 4005

Sridevi, N., Vishwe, P. S., & Prabhune, A. A. (2009) · Food Research International · doi:10.1016/j.foodres.2009.02.016 · Cited by 74

Cholic acid accumulation and its diminution by short-chain fatty acids in bifidobacteria

Kurdi, P., Tanaka, H., van Veen, H. W., Asano, K., Tomita, F., & Yokota, A. (2003) · Microbiology · doi:10.1099/mic.0.26376-0 · Cited by 70

Cholic Acid Is Accumulated Spontaneously, Driven by Membrane ΔpH, in Many Lactobacilli

Kurdi, P., van Veen, H. W., Tanaka, H., Mierau, I., Konings, W. N., Tannock, G. W., Tomita, F., & Yokota, A. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.22.6525-6528.2000 · Cited by 63

Isolation of a bile salt sulfatase-producing Clostridium strain from rat intestinal microflora

Huijghebaert, S., Mertens, J. A., & Eyssen, H. (1982) · Applied and Environmental Microbiology · doi:10.1128/aem.43.1.185-192.1982 · Cited by 61

Absence of Cholic Acid 7α-Dehydroxylase Activity in the Strains of Lactobacillus and Bifidobacterium

Takahashi, T., & Morotomi, M. (1994) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(94)77268-4 · Cited by 60

Bile salts hydrolase plays a key role on cholesterol removal by Lactobacillus reuteri

Taranto, M. P., Sesma, F. J. M., Holgado, A. P. D. R., & de Valdez, G. F. (1997) · Biotechnology Letters · doi:10.1023/a:1018373217429 · Cited by 58

Cholesterol Lowering Effect of Lactobacillus plantarum Isolated from Human Feces

Ha, C. G., Cho, J.-K., Lee, C., Chai, Y. G., Ha, Y. A., & Shin, S. H. (2006) · Journal of Microbiology and Biotechnology · Cited by 38

Molecular Cloning and Sequence Analysis of Bile Salt Hydrolase Gene ( bsh ) from Lactobacillus plantarum MBUL90 Strain of Human Origin

Kumar, R., Grover, S., Mohanty, A. K., & Batish, V. K. (2010) · Food Biotechnology · doi:10.1080/08905436.2010.507130 · Cited by 15

Listeria monocytogenes bile salt hydrolase is a virulence factor involved in the intestinal and hepatic phases of listeriosis

Dussurget, O., Cabanes, D., Dehoux, P., Lecuit, M., Buchrieser, C., Glaser, P., & Cossart, P. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.03230.x · Cited by 12

Molecular Identification and Typing of Putative Probiotic Indigenous Lactobacillus plantarum Strain Lp91 of Human Origin by Specific Primed-PCR Assays

Kumar, R., Grover, S., & Batish, V. K. (2011) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-011-9083-6 · Cited by 10

Bile acid metabolism and signaling, the microbiota, and metabolic disease

Cai, J., Rimal, B., Jiang, C., Chiang, J. Y. L., & Patterson, A. D. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2022.108238 · Cited by 529

The Role of Gut Microbiota on Cholesterol Metabolism in Atherosclerosis

Vourakis, M., Mayer, G., & Rousseau, G. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22158074 · Cited by 233

Lactobacillus bile salt hydrolase substrate specificity governs bacterial fitness and host colonization

Foley, M. H., O’Flaherty, S., Allen, G., Rivera, A. J., Stewart, A. K., Barrangou, R., & Theriot, C. M. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2017709118 · Cited by 205

Effect of probiotic Lactobacillus on lipid profile: A systematic review and meta-analysis of randomized, controlled trials

Wu, Y., Zhang, Q., Ren, Y., & Ruan, Z. (2017) · PLoS ONE · doi:10.1371/journal.pone.0178868 · Cited by 179

Cholesterol-Lowering Potentials of Lactic Acid Bacteria Based on Bile-Salt Hydrolase Activity and Effect of Potent Strains on Cholesterol Metabolism In Vitro and In Vivo

Tsai, C., Lin, P.-P., Hsieh, Y.-M., Zhang, Z., Wu, H.-C., & Huang, C.-C. (2014) · The Scientific World JOURNAL · doi:10.1155/2014/690752 · Cited by 149

In vitro bile salt hydrolase (BSH) activity screening of different probiotic microorganisms

Hernández-Gómez, J. G., López-Bonilla, A., Trejo-Tapia, G., Ávila-Reyes, S. V., Jiménez-Aparicio, A. R., & Hernández-Sánchez, H. (2021) · Foods · doi:10.3390/foods10030674 · Cited by 122

Evaluation of Bile salt hydrolase activity and cholesterol-binding ability of lactic acid bacteria isolated from milk and meconium

Dung Nguyen Thi*, T. N. T. T. (2026) · Ministry of Science and Technology Vietnam · doi:10.31276/vjste.2024.0098

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Islam, Z., Jahan, N., Liza, R. I., Sojib, M. S. I., Hasan, M. S., Ferdous, T., Islam, M. A., & Harun‐ur‐Rashid, M. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4111412 · Cited by 1

Bile Salt Hydrolase Activity Screening and Resistance to the Toxicity of Bile Salt by Indigenous Lactobacillus Isolates of Pakistan; A Research Article

(2010) · The Internet Journal of Microbiology · doi:10.5580/10b2

Newly characterized Lactiplantibacillus plantarum strains isolated from raw goat milk as probiotic cultures with potent cholesterol-lowering activity

Islam, Z., Jahan, N., Liza, R. I., Sojib, M. S. I., Hasan, M. S., Ferdous, T., Islam, M. A., & Harun‐ur‐Rashid, M. (2022) · Journal of Agriculture and Food Research · doi:10.1016/j.jafr.2022.100427 · Cited by 7