The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Enhancement strategies for transdermal drug delivery systems: current trends and applications
Open accessAbstract
Transdermal drug delivery systems have become an intriguing research topic in pharmaceutical technology area and one of the most frequently developed pharmaceutical products in global market. The use of these systems can overcome associated drawbacks of other delivery routes, such as oral and parenteral. The authors will review current trends, and future applications of transdermal technologies, with specific focus on providing a comprehensive understanding of transdermal drug delivery systems and enhancement strategies. This article will initially discuss each transdermal enhancement method used in the development of first-generation transdermal products. These methods include drug/vehicle interactions, vesicles and particles,stratum corneum modification, energy-driven methods and stratum corneum bypassing techniques. Through suitable design and implementation of active stratum corneum bypassing methods, notably microneedle technology, transdermal delivery systems have been shown to deliver both low and high molecular weight drugs. Microneedle technology platforms have proven themselves to be more versatile than other transdermal systems with opportunities for intradermal delivery of drugs/biotherapeutics and therapeutic drug monitoring. These have shown that microneedles have been a prospective strategy for improving transdermal delivery systems. Graphical abstract
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Cites
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
Nishita, M., Park, S.-Y., Nishio, T., Kamizaki, K., Wang, Z., Tamada, K., Takumi, T., Hashimoto, R., Otani, H., Pazour, G. J., et al. (2017) · Scientific Reports · doi:10.1038/s41598-016-0028-x · Cited by 15,947
Virological assessment of hospitalized patients with COVID-2019
Wölfel, R., Corman, V. M., Guggemos, W., Seilmaier, M., Zange, S., Müller, M. A., Niemeyer, D., Jones, T. C., Vollmar, P., Rothe, C., et al. (2020) · Nature · doi:10.1038/s41586-020-2196-x · Cited by 6,661
Liposomes in drug delivery: Progress and limitations
Sharma, A. (1997) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(97)00135-x · Cited by 1,253
McAllister, D. V., Wang, P. M., Davis, S. P., Park, J.-H., Canatella, P. J., Allen, M. G., & Prausnitz, M. R. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2331316100 · Cited by 859
Anatomy and Physiology of the Skin
Kolarsick, P. A. J., Kolarsick, M. A., & Goodwin, C. (2011) · Journal of the Dermatology Nurses' Association · doi:10.1097/jdn.0b013e3182274a98 · Cited by 578 · cited 1×
“0 m2 and accounts for 15% of the total body mass of an adult person [11].”
BackgroundSkin temperature: its role in thermoregulation
Romanovsky, A. A. (2014) · Acta Physiologica · doi:10.1111/apha.12231 · Cited by 518
Pappas, A. (2009) · Dermato-Endocrinology · doi:10.4161/derm.1.2.7811 · Cited by 326
Sebaceous-immunobiology is orchestrated by sebum lipids
Lovászi, M., Szegedi, A., Zouboulis, C. C., & Törőcsik, D. (2017) · Dermato-Endocrinology · doi:10.1080/19381980.2017.1375636 · Cited by 151
Merkel cells: A collective review of current concepts
Abraham, J., & Mathew, S. (2019) · International Journal of Applied and Basic Medical Research · doi:10.4103/ijabmr.ijabmr_34_18 · Cited by 63 · cited 1×
“Merkel cell, a functional cell of the sensory systems, and melanocytes are found in this layer [31, 32].”
BackgroundMolloy, G. J., Graham, H., & McGuinness, H. (2012) · BMC Public Health · doi:10.1186/1471-2458-12-838 · Cited by 56
Cited by
Recent advances in transdermal drug delivery systems: a review
Jeong, W. Y., Kwon, M., Choi, H. E., & Kim, K. S. (2021) · Biomaterials Research · doi:10.1186/s40824-021-00226-6 · Cited by 593
Aldawood, F. K., Andar, A., & Desai, S. (2021) · Polymers · doi:10.3390/polym13162815 · Cited by 499
Overcoming skin barriers through advanced transdermal drug delivery approaches
Phatale, V., Vaiphei, K. K., Jha, S., Patil, D., Agrawal, M., & Alexander, A. (2022) · Journal of Controlled Release · doi:10.1016/j.jconrel.2022.09.025 · Cited by 482
Metadata
- Authors
- Ramadon, D., McCrudden, M. T. C., Courtenay, A. J., & Donnelly, R. F.
- Venue
- Drug Delivery and Translational Research
- Published
- 2021-01-20
- Volume
- 12
- Issue
- 4
- Pages
- 758-791
- ISSN
- 2190-393X (ISSN-L)
- 2190-3948
- OpenAlex
- W3124563177
- Cited by
- 649
- References
- 10
- FWCI
- 28.33
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Ramadon, D., McCrudden, M. T. C., Courtenay, A. J., & Donnelly, R. F. (2022). Enhancement strategies for transdermal drug delivery systems: current trends and applications. Drug Delivery and Translational Research. https://doi.org/10.1007/s13346-021-00909-6
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