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The Impact of Novel Medications for Obesity on Weight Stigma and Societal Attitudes: A Narrative Review
Open accessAbstract
PURPOSE OF REVIEW: This narrative review examines the potential implications of the expanded use of novel medications for obesity, particularly the GLP-1 receptor agonists, on weight stigma and societal attitudes towards pharmacologically induced weight loss. It analyses how these medications may potentially contribute to both reducing and exacerbating stigma and discusses strategies to reduce weight bias. RECENT FINDINGS: The introduction of GLP-1 receptor agonists has demonstrated effectiveness in reducing weight and lead to improved health outcomes for individuals living with obesity. However, while these medications may reduce stigma by framing obesity as a medical issue rather than a personal failure, disparities in access and use related to high costs may inflate existing biases against those who cannot afford treatment. Also, a few studies indicate that users of these medications may feel stigmatised for taking what is perceived as an "easy way out" to lose weight, mirroring historical attitudes towards bariatric surgery. The new medications for obesity may have the potential to reduce obesity stigma by reframing it as a medical condition rather than a moral failing. However, taking legal actions to build a more inclusive society including ensuring equitable access to these medications will be essential in mitigating stigma and help fostering a supportive environment for those living with obesity. Lessons from reducing stigma surrounding other medical conditions suggest that supportive health care and educational campaigns that promote the understanding of obesity as a complex health issue are needed to reshape negative perceptions towards individuals with obesity.
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Data from bariatric surgery suggest that successful weight loss may not reduce weight stigma.
“However, data from bariatric surgery suggest that this may not be the case.122”
From The societal implications of using glucagon-like peptide-1 receptor agonists for the treatment of obesity (2025) · cites this paper as [122]
Stigma may be further exacerbated because there will be more treatments available, and those who do not engage with them may be blamed for not acting to manage their weight.
“If we look further ahead, stigma may be further exacerbated because there will be more treatments available, and those who do not engage with them may be blamed for not acting to manage their weight.122”
From The societal implications of using glucagon-like peptide-1 receptor agonists for the treatment of obesity (2025) · cites this paper as [122]
There is little direct evidence that classifying obesity as a disease will help to reduce stigma.
“However, there is little direct evidence that classifying obesity as a disease will help to reduce stigma.122”
From The societal implications of using glucagon-like peptide-1 receptor agonists for the treatment of obesity (2025) · cites this paper as [122]
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Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes
Lincoff, A. M., Brown-Frandsen, K., Colhoun, H. M., Deanfield, J., Emerson, S. S., Esbjerg, S., Hardt-Lindberg, S., Hovingh, G. K., Kahn, S. E., Kushner, R. F., et al. (2023) · New England Journal of Medicine · doi:10.1056/nejmoa2307563 · Cited by 3,236
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Joint international consensus statement for ending stigma of obesity
Rubino, F., Puhl, R. M., Cummings, D. E., Eckel, R. H., Ryan, D. H., Mechanick, J. I., Nadglowski, J., Ramos Salas, X., Schauer, P. R., Twenefour, D., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-0803-x · Cited by 1,152 · cited 3×
“…public about the stigma associated with obesity, and as discussed above, international multidisciplinary groups of experts and representatives from relevant scientific organisations have recently launched several joint consensus statements with recommendations to eliminate weight bias [1, 9, 59].”
Alkhezi, O. S., Alahmed, A. A., Alfayez, O. M., Alzuman, O. A., Almutairi, A. R., & Almohammed, O. A. (2023) · Obesity Reviews · doi:10.1111/obr.13543 · Cited by 139
Stigma toward substance use disorders: a multinational perspective and call for action
El Hayek, S., Foad, W., de Filippis, R., Ghosh, A., Koukach, N., Mahgoub Mohammed Khier, A., Pant, S. B., Padilla, V., Ramalho, R., Tolba, H., et al. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1295818 · Cited by 66
Weight stigma after bariatric surgery: A qualitative study with Brazilian women
Dimitrov Ulian, M., Fernandez Unsain, R., Rocha Franco, R., Aurélio Santo, M., Brewis, A., Trainer, S., SturtzSreetharan, C., Wutich, A., Gualano, B., & Baeza Scagliusi, F. (2023) · PLOS ONE · doi:10.1371/journal.pone.0287822 · Cited by 22
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Cited by
Sorted by citations
Scragg, J., Koutoukidis, D. A., Dirksen, C., Heitmann, B. L., & Jebb, S. A. (2025) · Med · doi:10.1016/j.medj.2025.100805 · Cited by 16
Self-citation
Metadata
- Authors
- Heitmann, B. L.
- Affiliations
- University of Copenhagen (DK)
- Corresponding author
- Heitmann, Berit L.
- ORCID
- Heitmann, Berit L.
- Venue
- Current Obesity Reports
- Published
- 2025-02-05
- Volume
- 14
- Issue
- 1
- Pages
- 18-18
- ISSN
- 2162-4968 (ISSN-L)
- PMC
- PMC11799028
- OpenAlex
- W4407151255
- Cited by
- 30
- References
- 6
- Citations by year
- 2026: 18 · 2025: 12
- FWCI
- 3.05
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Current Obesity Reports (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (publishedVersion, cc-by)
- Funders
- Parker Institute for Cancer Immunotherapy
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity and Health Practices
- Health Sciences › Medicine › Pharmacology (medical) › Pharmacology and Obesity Treatment
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Keywords
- obesity, weight stigma, GLP-1 receptor agonists, anti-obesity drugs, weight bias, social attitudes, pharmacological weight loss, access to treatment, bariatric surgery, stigma reduction, health equity
- MeSH terms
- Glucagon-Like Peptide-1 Receptor, Glucagon-Like Peptide-1 Receptor Agonists, Humans, Obesity, Stereotyping, Weight Loss, Anti-Obesity Agents, Social Stigma
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