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Examining the psychosis continuum

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DeRosse, Pamela, Karlsgodt, Katherine H.·2015·Current Behavioral Neuroscience Reports
DOI 10.1007/s40473-015-0040-7PMC PMC4454466
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Abstract

The notion that psychosis may exist on a continuum with normal experience has been proposed in multiple forms throughout the history of psychiatry. However, in recent years there has been an exponential increase in efforts aimed at elucidating what has been termed the 'psychosis continuum'. The present review seeks to summarize some of the more basic characteristics of this continuum and to present some of the recent findings that provide support for its validity. While there is still considerable work to be done, the emerging data holds considerable promise for advancing our understanding of both risk and resilience to psychiatric disorders characterized by psychosis.

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  • Genetic, neuropsychological, social, and environmental findings support a fully dimensional model in which nonclinical psychotic-like experiences and diagnosable psychotic disorders lie at opposite ends of a continuous distribution.

    “Convergent genetic, neuropsychological, social, and environmental findings support a “fully dimensional” model of psychosis or schizotypy, in which nonclinical psychotic-like experiences and diagnosable psychotic disorders form opposite ends of a continuous distribution (Claridge & Beech, 1995; DeRosse & Karlsgodt, 2015; M. T. Nelson et al., 2013).”

    From Narrative identity in the psychosis spectrum: A systematic review and developmental model (2021) · cites this paper as DeRosse & Karlsgodt, 2015

    The section “Evidence for Similarity Between Subclinical and Clinically Significant Psychosis” reviews genetic, demographic, experiential, and clinical evidence for a continuum; “Neurocognition” also discusses cognitive findings. But “Defining the Psychosis Continuum” says it is not yet clear whether the quasi-dimensional or fully dimensional model best fits the data. The paper therefore supports continuity, not the claim that these findings establish the fully dimensional model. (LLM, conf=0.90)

    Experimental — accuracy not yet measured

  • Little attention has been given to investigating whether the psychotic symptoms of healthy individuals are phenotypically similar to those of clinical populations.

    “Further, little attention has been given to investigating whether the psychotic symptoms of healthy individuals are phenotypically similar to those of clinical populations (DeRosse and Karlsgodt, 2015).”

    From Psychotic-Like Experiences at the Healthy End of the Psychosis Continuum (2017) · cites this paper as DeRosse and Karlsgodt, 2015

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Cited by

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Authors
DeRosse, P., & Karlsgodt, K. H.
Affiliations
Northwell Health (US)
Corresponding author
DeRosse, Pamela
ORCID
Venue
Current Behavioral Neuroscience Reports
Publisher
Springer Science and Business Media LLC
Published
2015-03-15
Volume
2
Issue
2
Pages
80-89
ISSN
2196-2979 (ISSN-L)
DOI
10.1007/s40473-015-0040-7
PMC
PMC4454466
OpenAlex
W2059215021
Cited by
145
References
7
Citations by year
2026: 10 · 2025: 20 · 2024: 15 · 2023: 15 · 2022: 19 · 2021: 17 · 2020: 12 · 2019: 10 · 2018: 11 · 2017: 11 · 2016: 3 · 2015: 2
FWCI
7.31
Type
journal article
Language
en
Open access
Licence
www.springer.com/tdm (tdm)
Locations
  • Current Behavioral Neuroscience Reports (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute of Mental Health (R00MH086756, R01MH079800)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
  • Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
Keywords
psychosis continuum, psychosis, psychosis risk, resilience, mental illness

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