Trial-Based Cognitive Therapy: Efficacy of a New CBT Approach for Treating Social Anxiety Disorder with Comorbid Depression.
Open accessAbstract
The present study aims to evaluate the efficacy of Trial-Based Cognitive Therapy (TBCT), a new cognitive-behavioral therapy approach, for generalized social anxiety disorder (GSAD) in a population with high rates of comorbid disorders, especially depression. This two-arm randomized clinical trial included 39 adults (TBCT = 18; waitlist group = 21) diagnosed with GSAD. The TBCT group received 16 weekly sessions of individual TBCT. Symptom severity was assessed at pre- and post-treatment. Participants in the TBCT group showed reduction in social anxiety, social avoidance, and depression, all associated with a large effect size. No differences between pre- and post-treatment scores were observed in the waitlist condition. Results also showed that comorbidity significantly moderated treatment efficacy. Patients with comorbid conditions showed greater reductions in social anxiety symptoms across treatment than those with SAD only. In summary, TBCT was effective in reducing social anxiety and depressive symptoms, particularly for patients with comorbidity.
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Cites
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Claims the paper makes
17 of 58 cited sources checked · 10 supported · 0 flagged · accuracy not yet measured
- Study design and conductcitation
The Social Phobia Inventory (SPIN) is a reliable measure for evaluating treatment change in social anxiety symptoms.
“The SPIN distinguishes socially anxious individuals from normal controls by using a 19-point cut-off and is a reliable measure for evaluating treatment change in social anxiety symptoms (Connor et al. 2000;Osório et al. 2009).”
Quote in the paperSubstantial claim2 of 2 sources checked - Premisecitation
Current literature has suggested that cognitive factors function as maintenance factors in SAD.
“Indeed, current literature has suggested that cognitive factors function as maintenance factors in SAD (Hofmann 2007).”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Hofmann 2007 source
- Premisecitation
In that randomized clinical trial, TBCT was more efficacious than CBT in reducing fear of negative evaluation, social avoidance, and distress.
“Results indicated that TBCT was just as efficacious as conventional CBT techniques in reducing social anxiety symptoms and improving quality of life, and more efficacious than CBT in reducing fear of negative evaluation, social avoidance, and distress (de Oliveira et al. 2012b;Powell et al. 2013).”
Quote in the paperSubstantial claim1 of 2 sources checked- cites de Oliveira et al. 2012b
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Powell et al. 2013 source
The Discussion reports significantly lower fear-of-negative-evaluation scores with the trial-based thought record (TBTR) than with conventional cognitive therapy (CCT). It does not report a comparative result for social avoidance or distress; the Introduction says other clinical outcomes were detailed in an earlier publication. The trial tested TBTR against specified CCT techniques, rather than the broader TBCT approach against CBT generally. (LLM, conf=0.87)
Experimental — accuracy not yet measured
- Study design and conductcitation
Another limitation is related to potential therapist effects, which has implications for evaluating the treatment outcome.
“Another limitation is related to potential therapist effects, which has implications for evaluating the treatment outcome (Thompson et al. 2012;Walwyn and Roberts 2010).”
Quote in the paperNot a substantial claim1 of 2 sources checked - Premisecitation
There is a lower therapist effect when interventions follow a manual-based treatment or protocol, when therapists receive solid training in the intervention and have considerable clinical experience.
“However, there is a lower therapist effect when interventions follow a manual-based treatment or protocol, when therapists receive solid training in the intervention and have a considerable clinical experience (Thompson et al. 2012).”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Thompson et al. 2012 source
The Introduction says evidence suggests therapist effects are less likely with highly standardized, manual-based treatments or highly skilled, experienced, well-trained therapists. The claim presents this as an established lower therapist effect, whereas the source describes a lower likelihood and qualifies the evidence. (LLM, conf=0.85)
Experimental — accuracy not yet measured
- Interpretationcitation
The results of this randomized clinical trial are consistent with the TBCT literature, especially those related to SAD.
“The results of this randomized clinical trial are consistent the TBCT literature as well (de Oliveira 2008;de Oliveira et al. 2012b;Delavechia et al. 2016), especially those related to SAD (de Oliveira et al. 2012b;Powell et al. 2013).”
Quote in the paperNot a substantial claim2 of 3 sources checked - Interpretationcitation
This study's results are consistent with previous research and meta-analyses showing that CBT is effective for social anxiety disorder.
“This study aligns with previous research about the efficacy of CBT on SAD symptoms.”
- Also stated in: § Discussion · boosted
“It is consistent with a recent meta-analysis that evaluated the effect of CBT in treating SAD (Acarturk et al. 2009), and recent studies that show that CBT is highly effective in treating SAD (Barkowski et al. 2016;Hofmann et al. 2013;Ponniah and Hollon 2008;Otte 2011).”
Quote in the paperNot a substantial claim1 of 3 sources checked- cites Acarturk et al. 2009 source
- cites Barkowski et al. 2016 source
- cites Hofmann et al. 2013 source
The Discussion reports response rates above 70% in both CBT groups and cites earlier CBT trials with response rates of 50.8% and 47.1%, supporting the stated alignment with previous research on CBT for social anxiety disorder. The passage does not report a meta-analysis, so that additional part of the paraphrased claim is not supported by our copy. (LLM, conf=0.82)
Experimental — accuracy not yet measured
- Also stated in: § Discussion · boosted
- Findingcitation
All within and between-group effect sizes were in the large range.
“Consistent with established precedent (Cohen 1988), all of the within and between-group effect sizes were in the large range.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Cohen 1988
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Findingown data
TBCT resulted in statistically significant reductions in all outcome measures except fear of negative evaluation between pre- and post-treatment analyses.
“As indicated in Table 2, TBCT resulted in statistically significant reductions in all outcome measures except fear of negative evaluation between pre-and post-treatment analyses”
Quote in the paperSubstantial claim - Findingown data
TBCT resulted in statistically significant reductions in social anxiety and depression symptoms in ANCOVA, controlling for baseline differences and baseline levels of each outcome variable.
“and in social anxiety and depression symptoms in ANCOVA, controlling for baseline differences and baseline levels of each outcome variable.”
Quote in the paperSubstantial claim - Findingown data
The between-group difference in social anxiety symptoms was associated with a large effect size (d = 1.53).
“Moreover, this between-group difference was associated with a large effect size (d = 1.53).”
Quote in the paperSubstantial claim - Findingown data
Individuals with comorbid conditions evidenced greater reductions in social anxiety symptoms (γ = -27.64, P < .01) than did those with only social anxiety disorder (γ = -16.29, P < .01).
“Specifically, individuals with comorbid conditions evidenced greater reductions in social anxiety symptoms (γ = -27.64,P < .01)than did those with only social anxiety disorder (γ = -16.29,P < .01).”
Quote in the paperSubstantial claim - Findingown data
In this study, which compared the intervention to a waitlist condition, TBCT had an even larger effect (d = 1.53).
“In our study, which also compares the intervention to a waitlist condition, we found even a larger effect for TBCT (d = 1.53).”
Quote in the paperSubstantial claim - Findingown data
TBCT seems to be particularly efficacious in patients with comorbid conditions.
“and it seems to be particularly efficacious in patients with comorbid conditions.”
Quote in the paperSubstantial claim - Findingown data
The between-group difference in depression symptoms was associated with a large effect size (d = 1.05).
“Moreover, this between-group difference was associated with a large effect size (d = 1.05)”
Quote in the paperSubstantial claim - Findingown data
Only comorbidity significantly moderated treatment efficacy (γ = -11.35, P < .05).
“Results revealed that only comorbidity significantly moderated treatment efficacy (γ = -11.35,P < .05).”
Quote in the paperSubstantial claim - Findingown data
The conditional latent change score model for social anxiety symptoms evidenced good fit with a nonsignificant chi-square statistic (χ2 = 2.54, P = .27), CFI = 0.98, TLI = 0.98, and RMSEA = 0.08.
“The conditional latent change score model for social anxiety symptoms evidenced good fit with a nonsignificant chi-square statistic (χ 2 = 2.54, P = .27),as well as good fit indices (i.e., CFI = 0.98; TLI = 0.98; and RMSEA = 0.08)”
Quote in the paperSubstantial claim - Findingown data
The new conditional latent change score model for depression symptoms, with a covariance parameter between the latent change score and pre-treatment depression symptoms, evidenced good fit with a non-significant chi-square statistic (χ2 = 2.40, P = .30) and good fit indices (CFI = 0.97; TLI = 0.93; RMSEA = 0.07).
“The new model evidenced good fit with a non-significant chi-square statistic (χ 2 = 2.40, P = .30),as well as good fit indices (i.e., CFI = 0.97; TLI = 0.93; and RMSEA = 0.07).”
Quote in the paperSubstantial claim - Findingown data
In this study, TBCT produced a larger effect size (d = 1.05) on depression measures.
“and in our study, we observed a larger effect size (d = 1.05),”
Quote in the paperSubstantial claim - Findingown data
Comorbidity significantly moderated treatment efficacy.
“Interestingly, results showed that comorbidity significantly moderated treatment efficacy.”
Quote in the paperSubstantial claim - Findingown data
TBCT was effective in reducing symptoms of social avoidance and distress as measured by the SADS.
“Furthermore, TBCT was effective in reducing symptoms of social avoidance and distress as measured by the SADS.”
Quote in the paperSubstantial claim - Findingown data
The between-group difference for social avoidance and distress was associated with a large effect size (d = 1.07).
“It is important to note that these symptoms are the cardinal characteristics of social anxiety disorder, and the between-group difference for these symptoms was associated with a large effect size (d = 1.07).”
Quote in the paperSubstantial claim - Premisecitation
When comparing therapists with different levels of experience, there were no differences in treatment outcome.
“When comparing therapists with different levels of experience, there were no differences in treatment outcome, indicating that the treatment may be a helpful tool even for clinicians that are relatively unfamiliar with it.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites de Oliveira et al. (2012a, b) source
- Premisecitation
Patients with comorbid diagnoses of SAD and depression drop out more frequently than patients with depression alone.
“Additionally, patients with comorbid diagnoses of SAD and depression drop out more frequently than patients with depression alone (Brown et al. 1996).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Brown et al. 1996 source
- Interpretationreasoning
This is the first randomized clinical trial comparing the effect of a TBCT intervention to a waitlist condition for SAD.
“As far as we know, there have been no studies evaluating the application of the entire TBCT protocol treatment for individuals diagnosed with SAD and other conditions.Thus, this is the first randomized clinical trial comparing the effect of a TBCT intervention to a waitlist condition for SAD.”
Quote in the paperSubstantial claim - Premisecitation
In a replication with 166 patients with varying diagnoses and comorbidities, TBCT showed a significant reduction in attachment to dysfunctional CBs and emotional intensity.
“In a replication of this study, de Oliveira et al. (2012a, b) evaluated the effect of the intervention in 166 patients with varying diagnoses as well as varying comorbidities.Results from this study showed a significant reduction in the attachment to dysfunctional CBs and in emotional intensity.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites de Oliveira et al. (2012a, b) source
- Interpretationown data
TBCT may be very effective in treating the depression symptoms associated with SAD condition.
“indicating that TBCT may be very effective in treating the depression symptoms associated with SAD condition.”
Quote in the paperSubstantial claim - Interpretationcitation
When compared with randomized clinical trials that evaluated the effect of CBT using waitlist conditions, the effect size of this study is even larger.
“However, when compared with randomized clinical trials that evaluated the effect of CBT using waitlist conditions, the effect size of this study is even larger (Acarturk et al. 2009).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Acarturk et al. 2009 source
- Premisecitation
The meta-analysis found a mean effect size for social avoidance and distress measure of .70.
“Finally, it is important to highlight that the authors found a mean effect size for social avoidance and distress measure of .70.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Acarturk et al. 2009 source
- Premisecitation
The mean effect size observed in studies that delivered the intervention in an individual format was .61.
“The mean effect size observed in studies that delivered the intervention in an individual format was .61,”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Acarturk et al. 2009 source
- Interpretationcitation
The results obtained in the present study could be inflated given the adopted waitlist control condition.
“Thus, the results obtained in the present study could be inflated given the adopted control condition.”
Quote in the paperSubstantial claim - Interpretationreasoning
TBCT may be a promising treatment for chronic GSAD patients that do not benefit from current CBT, especially those with comorbid conditions.
“TBCT may be a promising treatment for chronic GSAD patients that do not benefit from current CBT, especially those with comorbid conditions.”
Quote in the paperSubstantial claim - Interpretationcitation
Estimates of treatment efficacy were not overestimated in the current study.
“This could suggest that estimates of treatment efficacy were not overestimated in the current study.”
Quote in the paperNot a substantial claim - Premisecitation
Waitlist conditions have a larger effect size than studies that compare the treatment with placebo or treatment-as-usual control groups.
“Additionally, waitlist conditions have a larger effect size than studies that compare the treatment with placebo or treatment-as-usual control groups (Acarturk et al. 2009).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Acarturk et al. 2009 source
- Premisecitation
Prior research has indicated that self-report measures may be a more conservative estimate of treatment efficacy than clinician-rated assessments.
“Furthermore, it should be noted that a prior research has indicated that self-report measures may be a more conservative estimate of treatment efficacy than clinician-rated assessments (Cuijpers et al. 2010).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Cuijpers et al. 2010 source
- Interpretationreasoning
The presence of comorbidity in this clinical trial increases its external validity.
“Thus, the presence of comorbidity in this clinical trial increases its external validity,”
Quote in the paperSubstantial claim- Rests on an assumption: Comorbidity is common in SAD (the rule rather than the exception).
- Rests on an assumption: Clinicians treating SAD commonly have to deal with depression and other conditions associated with social anxiety.
- Study design and conductown data
The first limitation of this study is significant baseline differences across the two conditions.
“The first one is related to significant baseline differences across the two conditions.”
Quote in the paperNot a substantial claim - Premisecitation
In studies comparing treatment with waitlist control groups only, the meta-analysis found a significantly larger effect size of .86.
“Considering the studies that compared the treatment with waitlist control groups only, the authors found a significantly larger effect size of .86.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Acarturk et al. 2009 source
- Study design and conductreasoning
As only one therapist delivered the treatment in this study, it is not possible to evaluate therapist bias.
“As only one therapist delivered the treatment in this study, it is not possible to evaluate therapist bias.”
Quote in the paperNot a substantial claim - Study design and conductown data
The number of subjects in the experimental group with a prior SAD diagnosis and psychotropic medication at intake was higher than in the waitlist condition.
“Although the subjects were randomized by an independent researcher, the number of subjects in the experimental group with a prior SAD diagnosis and psychotropic medication at intake was higher than in the waitlist condition.”
Quote in the paperNot a substantial claim - Premisecitation
A meta-analysis of randomized clinical trials found a mean effect size of .70 for CBT on SAD measures.
“That meta-analysis only included randomized clinical trials and found a mean effect size of .70 for SAD measures.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Acarturk et al. 2009 source
- Premisecitation
The mean effect size of CBT treatment on depression measures was .70.
“Moreover, the mean effect size of CBT treatment on depression measures was .70,”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Acarturk et al. 2009 source
- Study design and conductown data
Significant group differences emerged even after controlling for baseline differences.
“Nevertheless, significant group differences emerged even after controlling for baseline differences.”
Quote in the paperSubstantial claim - Interpretationown data
TBCT was effective in reducing depression symptoms.
“Additionally, TBCT was effective in reducing depression symptoms as the TBCT participants experienced significantly greater reductions in BDI-II relative to the waitlist condition.”
Quote in the paperSubstantial claim - Interpretationown data
TBCT was effective in reducing social anxiety symptoms.
“Consistent with our primary hypothesis, TBCT was effective in reducing social anxiety symptoms as the participants in the TBCT group experienced greater reductions in SPIN relative to participants in the waitlist condition.”
Quote in the paperSubstantial claim
- May combine two claims. 34
- Classified as probably not a substantial claim. 18
- The quote only partly states this claim. 1
May combine two claims.
PremisecitationIn a randomized clinical trial comparing TBCT techniques to conventional CBT techniques for GSAD, TBCT was just as efficacious as conventional CBT in reducing social anxiety symptoms and improving quality of life.
“Results indicated that TBCT was just as efficacious as conventional CBT techniques in reducing social anxiety symptoms and improving quality of life, and more efficacious than CBT in reducing fear of negative evaluation, social avoidance, and distress (de Oliveira et al. 2012b;Powell et al. 2013).”
Quote in the paperSubstantial claim1 of 2 sources checked- cites de Oliveira et al. 2012b
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Powell et al. 2013 source
The Methods describe a randomized comparison of trial-based thought record (TBTR) and conventional cognitive therapy in patients with generalized social anxiety disorder. The Results and Discussion report that both approaches improved several quality-of-life domains, with TBTR outperforming the comparator in some domains. This paper does not establish that they were equally effective at reducing social anxiety symptoms; the Introduction says detailed clinical outcomes were published elsewhere. (LLM, conf=0.86)
Experimental — accuracy not yet measured
May combine two claims.
PremisecitationThe combination of SAD and depression is associated with more severe suffering and impairment, making it more difficult to treat.
“Furthermore, the combination of the two disorders has been associated with more severe suffering and impairment (Dalrymple and Zimmerman 2007), making it more difficult to treat (Belzer and Schneier 2004;Fracalanza et al. 2014).”
Quote in the paperSubstantial claim1 of 3 sources checkedMay combine two claims.
PremisecitationDespite the well-established efficacy of CBT as the gold treatment for SAD, a significant portion of patients do not improve after treatment.
“Despite the well-established efficacy of CBT as the gold treatment for SAD, a significant portion of patients do not improve after treatment (Hofmann 2007).”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Hofmann 2007 source
May combine two claims.
PremisecitationIn 30 patients with different diagnoses, TBCT effectively decreased the attachment to dysfunctional CBs, as well as the emotional intensity, during a session.
“In 30 patients with different diagnoses, this treatment effectively decreased the attachment to the dysfunctional CBs, as well as the emotional intensity, during a session (de Oliveira 2008).”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites de Oliveira 2008 source
May combine two claims.
PremisecitationTBCT was effective for 39 patients with different diagnoses, substantiating TBCT as a putative transdiagnostic intervention.
“Another study showed that TBCT was effective for 39 patients with different diagnoses, substantiating TBCT as a putative transdiagnostic intervention (Delavechia et al. 2016).”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites Delavechia et al. 2016 source
The Methods describe 39 outpatients with varied psychiatric diagnoses receiving one session of trial-based thought record (TBTR), and the Results report reduced adherence to negative core beliefs and related emotions. The study tested this TBCT technique, not TBCT as a whole, and the Discussion identifies the heterogeneous sample and single-session observation as limitations. It therefore does not establish TBCT's effectiveness as a transdiagnostic intervention. (LLM, conf=0.88)
Experimental — accuracy not yet measured
May combine two claims.
PremisecitationIn a recent trial comparing The Trial to conventional CBT techniques for generalized SAD, The Trial was as effective as conventional CBT tools, with a large within-group effect size (d = 1.01 for TBCT vs d = 0.83 for conventional CBT).
“In a recent trial that evaluated the effect of the main TBCT technique (The Trial) compared to conventional CBT techniques for generalized SAD, it was observed that The Trial was as effective as conventional CBT tools, with a large within-group effect size (d = 1.01 for the TBCT technique vs d = 0.83 for conventional CBT tools) (de Oliveira et al. 2012b;Powell et al. 2013).”
Quote in the paperNot a substantial claim1 of 2 sources checked- cites de Oliveira et al. 2012b
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Powell et al. 2013 source
The Methods describe a randomized comparison of TBTR with conventional cognitive therapy in patients with generalized SAD, and the Abstract concludes that TBTR was at least as effective for several quality-of-life domains. However, Table 2 and the Discussion report domain-specific effect sizes, not the claimed within-group values of d = 1.01 and d = 0.83; the paper says detailed clinical outcomes were published elsewhere. Page numbers are unavailable in our copy. (LLM, conf=0.90)
Experimental — accuracy not yet measured
May combine two claims.
PremisecitationStudies show that The Trial technique is effective in reducing attachment to dysfunctional core beliefs and associated emotional intensity, as well as social anxiety symptoms.
“Studies that evaluated the effect of The Trial technique in various psychiatric disorders (de Oliveira 2008;de Oliveira et al. 2012a, b;Delavechia et al. 2016), and also in generalized SAD (de Oliveira et al. 2012b;Powell et al. 2013) show that this technique is effective in reducing the attachment to dysfunctional CBs and the associated emotional intensity, as well as social anxiety symptoms.”
Quote in the paperSubstantial claim2 of 3 sources checked- cites de Oliveira 2008 source
The Results report significant within-session reductions in belief in core beliefs and the intensity of corresponding emotions. The Discussion calls this a small, preliminary study and says randomized trials are needed before firm conclusions about effectiveness; the unqualified effectiveness claim therefore overstates this source. The citing sentence attaches the social-anxiety-symptom claim to later citations, not to the 2008 paper. (LLM, conf=0.87)
Experimental — accuracy not yet measured - cites de Oliveira et al. 2012a source
- cites Delavechia et al. 2016 source
May combine two claims.
Findingown dataDiagnostic interviews revealed that 24 participants had at least one additional comorbid condition, with depression being the most common additional diagnosis (n = 16).
“Diagnostic interviews revealed that 24 participants had at least one additional comorbid condition, with depression being the most common additional diagnosis (n = 16).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataIn this study, there was a large within-group effect size for the social anxiety measure (d = 2.1), with a similar sample size and drop-out rates as previous studies.
“In our study, we also found a large within-group effect size for the social anxiety measure (d = 2.1), with a similar sample size and drop-out rates as previous studies.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataIndividuals in the waitlist control group did not evidence significant change from pre-treatment to post-treatment, and all of the effect sizes were in the small range.
“Individuals in the waitlist control group did not evidence significant change from pre-treatment to post-treatment, and all of the effect sizes were in the small range.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataTreatment condition significantly predicted the latent change score for social anxiety symptoms (γ = -22.73, P < .01), indicating that individuals in the TBCT condition experienced significantly greater reductions in social anxiety symptoms relative to waitlist control.
“Our primary hypothesis was corroborated, as treatment condition significantly predicted the latent change score (γ = -22.73,P < .01).This suggests that, on average, individuals in the TBCT condition experienced significantly greater reductions in social anxiety symptoms relative to waitlist control.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataTBCT was effective in reducing symptoms of social avoidance and distress, with a larger effect size (d = 1.07) than previously found.
“We also found that TBCT was effective in reducing symptoms of social avoidance and distress, although with a larger effect size (d = 1.07) than previously found.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataTreatment condition significantly predicted the latent change score for depression symptoms (γ = -11.15, P < .01), indicating that individuals in the TBCT condition experienced significantly greater reductions in depression symptoms relative to waitlist control.
“Furthermore, the hypothesis for differential efficacy for depression outcome was supported, as treatment condition significantly predicted the latent change score (γ = -11.15,P < .01).This suggests that, on average, individuals in the TBCT condition experienced significantly greater reductions in depression symptoms relative to waitlist control.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataTBCT is effective in reducing social anxiety symptoms and depression symptoms.
“This study suggests that TBCT is effective in reducing social anxiety symptoms and depression symptoms,”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataThe original conditional latent change score model for depression symptoms exhibited mediocre fit with a significant chi-square statistic (χ2 = 12.95, P = .01) and poor fit indices (CFI = 0.35; TLI = 0.00; RMSEA = 0.29).
“The original conditional latent change score model for depression symptoms exhibited mediocre fit with a significant chi-square statistic (χ 2 = 12.95, P = .01),as well as poor fit indices (i.e., CFI = 0.35; TLI = 0.00; and RMSEA = 0.29).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataAfter controlling for baseline differences, the effects of treatment condition on changes in symptoms of social anxiety and depression remained significant (γ = -20.70, P < .01; γ = -10.90, P < .01, respectively).
“These analyses were re-conducted controlling for baseline differences.The effects of treatment condition on changes in symptoms of social anxiety and depression remained significant (γ = -20.70,P < .01;γ = -10.90,P < .01,respectively).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataNone of the other interaction effects were significant, including age, gender, prior history of a social anxiety disorder diagnosis, or psychotropic medication intake.
“None of the other interaction effects were significant, including age (γ = 0.38, P = .44),gender (γ = -5.69,P = .35),prior history of a social anxiety disorder diagnosis (γ = -5.30,P = .95),or psychotropic medication intake (γ = -6.86,P = .26).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataIndividuals in the TBCT group with comorbid conditions evidenced greater reductions in social anxiety symptoms than those with SAD only and were those most benefited by the treatment.
“The individuals in the TBCT group with comorbid conditions evidenced greater reductions in social anxiety symptoms than those with SAD only and were those most benefited by the treatment.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationCBT is considered the gold-standard treatment for SAD.
“Although pharmacotherapy is effective for SAD (Curtiss et al. 2017), cognitivebehavioral therapy (CBT) is considered the gold-standard treatment (Rodebaugh et al. 2004).”
Quote in the paperNot a substantial claim0 of 2 sources checkedClassified as probably not a substantial claim. May combine two claims.
Study design and conductown dataParticipants were randomly assigned to TBCT or waitlist by an independent researcher not participating in the study.
“An independent researcher who was not participating in the study provided the randomization schedule of the participants between the two conditions.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductreasoningPsychotropic medication intake and previous SAD diagnosis were entered as covariates in subsequent analyses, as well as other demographic variables.
“Thus, psychotropic medication intake and previous SAD diagnosis were entered as covariates in subsequent analyses, as well as other demographic variables.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
PremisecitationTBCT has its own specific cognitive conceptualization, techniques, and instruments, making it a unique and distinct intervention.
“However, this variation of the CBT approach has its own specific cognitive conceptualization, techniques, and instruments, making it a unique and distinct intervention (de Oliveira 2015; de Oliveira et al. 2015;Morrison et al. 2015).”
Quote in the paperSubstantial claim0 of 3 sources checked- cites de Oliveira 2015
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites de Oliveira et al. 2015
- cites Morrison et al. 2015 source
May combine two claims.
PremisecitationForty percent of patients request subsequent treatment within a year after having received CBT, and just 48% of the patients are classified as responders after the termination of treatment.
“Forty percent of patients request subsequent treatment within a year after having received CBT (Gilian et al. 1984), and just 48% of the patients are classified as responders after the termination of treatment (Heimberg et al. 1998).”
Quote in the paperSubstantial claim0 of 2 sources checkedClassified as probably not a substantial claim.
Study design and conductown dataAll P values were submitted to false discovery rate correction.
“To address multiple comparisons, all P values were submitted to false discovery rate correction.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
Study design and conductcitationSAD diagnosis was determined using the SAD module of the Structured Clinical Interview for DSM-IV-Research Version (SCID-I/P 2.0).
“We used the SAD module of the Structured Clinical Interview for DSM-IV-Research Version (SCID-I/P 2.0), developed by First et al. (2002) to determine SAD diagnosis.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites First et al. (2002)
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
PremisecitationSeveral randomized clinical trials corroborate the efficacy of CBT for SAD, with a mean effect size of .70.
“Several randomized clinical trials corroborate the efficacy of CBT for SAD (Barkowski et al. 2016;Hofmann and Smits 2008;Hofmann et al. 2013;Olatunji et al. 2010;Otte 2011;Ponniah and Hollon 2008), with a mean effect size of .70 (Acarturk et al. 2009).”
Quote in the paperSubstantial claim0 of 2 sources checkedMay combine two claims.
PremisecitationCBT for comorbid SAD and depression reduces anxiety symptoms, yet the symptoms of depression remain elevated.
“Research shows that CBT for comorbid SAD and depression reduces anxiety symptoms, yet the symptoms of depression remain elevated (Joormann et al. 2005).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Joormann et al. 2005 source
May combine two claims.
Study design and conductown dataNo other group differences were observed in the demographic variables, nor were there any differences present between assessment measures at baseline.
“No other group differences were observed in the demographic variables, nor were there any differences present between assessment measures at baseline.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationSAD is a significant risk factor for the subsequent occurrence of depressive symptoms, with anxiety onset typically preceding that of depression.
“Thus, SAD is a significant risk factor for the subsequent occurrence of depressive symptoms, with anxiety onset typically preceding that of depression (Kessler et al. 1999).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Kessler et al. 1999 source
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataAll 18 patients in the TBCT group included in the analyses received at least 85% of the treatment.
“Thus, all the 18 patients in the TBCT group included in the analyses received at least 85% of the treatment (1 patient received 14 sessions and 17 patients received 16 sessions).”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductown dataParticipants in the TBCT condition differed from the waitlist control regarding psychotropic medication intake and previous SAD diagnosis, with more patients in the treated group taking medication and having received a previous SAD diagnosis.
“Participants in the TBCT condition differed from the waitlist control regarding psychotropic medication intake and previous SAD diagnosis.There were more patients in the treated group that were taking this type of medication [χ 2 (1) = 7.84, P = .005]and had received a previous SAD diagnosis [χ 2 (1) = 4.70, P = .03].”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataOf 27 participants assigned to TBCT, 9 were excluded from analysis (1 withdrew after random allocation, 1 was excluded after the first session for receiving other psychotherapy simultaneously, and 7 withdrew before finishing half of the treatment).
“Of the 27 participants who were assigned to TBCT treatment, 9 were excluded from the analysis for the following reasons: 1 participant withdrew after the random allocation, 1 participant was excluded after the first session for receiving other psychotherapy simultaneously, and 7 withdrew before finishing half of the treatment (these participants received less than 7”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenMissing data were accommodated with full-information maximum likelihood estimation.
“Missing data were accommodated with full-information maximum likelihood estimation.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
PremisecitationComorbid disorders are the rule rather than the exception for SAD, with major depressive disorder frequently co-occurring with SAD.
“Comorbid disorders are the rule rather than the exception for SAD, with major depressive disorder frequently co-occurring with SAD (Erwin et al. 2002;Klemanski et al. 2016;Ohayon and Schatzberg 2010).”
Quote in the paperSubstantial claim0 of 3 sources checkedProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataOf 35 participants assigned to waitlist control, 14 were excluded from analysis (1 for taking anxiolytic medication during the pre- and post-test interval and 13 withdrew after the pre-test assessment).
“Of the 35 participants who were assigned to the waitlist control, 14 were excluded from the analysis for the following reasons: 1 participant was excluded for taking anxiolytic medication during the pre-and post-test interval and 13 withdrew after the pre-test assessment.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationown dataResults support TBCT as a promising intervention to treat not only SAD, but also the comorbid symptoms.
“Alongside the large effect size found for TBCT on depression symptoms, results support TBCT as a promising intervention to treat not only SAD, but also the comorbid symptoms.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S4 (based).
Interpretationnone givenThis is the first two-arm randomized clinical trial comparing TBCT and a control condition (waitlist group) for the treatment of generalized SAD.
“It is the first two-arm randomized clinical trial comparing TBCT and a control condition (waitlist group) for the treatment of generalized SAD.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationown dataTBCT may be effective not only in reducing social anxiety symptoms, but other comorbid conditions as well, especially depression.
“These results indicate that TBCT may be effective not only in reducing social anxiety symptoms, but other comorbid conditions as well, especially depression.”
Quote in the paperSubstantial claimMay combine two claims.
Interpretationown dataThe baseline differences in psychotropic medication intake and previous SAD diagnosis may indicate that patients randomized to the TBCT group may have experienced a more chronic and severe form of SAD, which may impact the treatment response.
“This may indicate that the patients randomized to the TBCT group may have experienced a more chronic and severe form of SAD, which may impact the treatment response.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductreasoningThe reliance on self-report measures to assess primary outcomes might be a limitation.
“Additionally, the reliance on self-report measures to assess primary outcomes might be a limitation.”
Quote in the paperNot a substantial claim- Rests on an assumption: Self-report instruments are amenable to response biases such as social desirability and consistency seeking.
Classified as probably not a substantial claim.
Study design and conductnone givenA further limitation of this study is the small sample size.
“Finally, a further limitation of this study is the small sample size.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S2 (checkable).
Study design and conductreasoningThe results must be interpreted as preliminary.
“Thus, the results must be interpreted as preliminary.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
PremisecitationThe main TBCT technique (The Trial) is a novel approach in the field designed to challenge and restructure dysfunctional core beliefs.
“Although TBCT contains CBT techniques, such as psychoeducation, evaluation of automatic thoughts, and exposure, the main TBCT technique (The Trial) is a novel approach in the field designed to challenge and restructure dysfunctional CBs (de Oliveira 2015; de Oliveira et al. 2015).”
Quote in the paperSubstantial claim0 of 2 sources checked- cites de Oliveira 2015
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites de Oliveira et al. 2015
Probably not a substantial claim: may not pass S2 (checkable).
PremisecitationData based on effects of the waitlist condition may be helpful as a benchmark in pilot studies that evaluate new treatments.
“Additionally, it is important to highlight that data based on effects of the waitlist condition may be helpful as a benchmark in pilot studies that evaluate new treatments (Steinert et al. 2017).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Steinert et al. 2017 source
May combine two claims.
Study design and conductnone givenIn the current study, a manualized protocol was used, and the therapist received extensive training in the intervention.
“In the current study, a manualized protocol was used, and the therapist received extensive training in the intervention.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationIndividuals with SAD randomized to the waitlist condition exhibit small changes waiting for the intervention and remain symptomatic after this period.
“Research suggests that individuals with SAD randomized to the waitlist condition exhibit small changes waiting for the intervention, and remain symptomatic after this period (Steinert et al. in press).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Steinert et al. in press
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
InterpretationreasoningThe waitlist condition in this study may be more appropriate because this is the first randomized clinical trial that evaluated the effect of TBCT for generalized SAD.
“This may make the waitlist condition in this study more appropriate, as this is the first randomized clinical trial that evaluated the effect of TBCT for generalized SAD.”
Quote in the paperSubstantial claim- Rests on an assumption: This is the first randomized clinical trial evaluating TBCT for generalized SAD.
The quote only partly states this claim.
InterpretationreasoningThe individual-format mean effect size of .61 supports the efficacy of TBCT in treating SAD symptoms.
“which additionally supports the efficacy of the TBCT in treating SAD symptoms.”
Quote in the paperSubstantial claim
The authors state this as an assumption.
The latent change score model assumes stability in changes across time (the pathway from T1 to the latent change score is fixed to 0).
“Furthermore, the pathway from T1 to the latent change score was fixed to 0, which indicates stability in changes.If this assumption was not upheld, as indicated by poor model fit, then a covariance parameter between T1 and the latent change score was permitted.”
The paper relies on this without support.
Comorbidity is common in SAD (the rule rather than the exception).
“This is an important finding as the presence of comorbidity in SAD is the rule rather than the exception.”
The paper relies on this without support.
This is the first randomized clinical trial evaluating TBCT for generalized SAD.
“This may make the waitlist condition in this study more appropriate, as this is the first randomized clinical trial that evaluated the effect of TBCT for generalized SAD.”
The paper relies on this without support.
Self-report instruments are amenable to response biases such as social desirability and consistency seeking.
“Self-report instruments are amenable to a number of response biases (e.g., social desirability and consistency seeking).”
The paper relies on this without support.
Clinicians treating SAD commonly have to deal with depression and other conditions associated with social anxiety.
“Clinicians that treat patients with SAD commonly have to deal with depression and other conditions associated with social anxiety.”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Stated condition coding reverses the interpretation of the change coefficient
MinorWith TBCT coded 1 and waitlist coded 2, the negative coefficient means the waitlist group has a lower latent change score. Because the score is defined as post-treatment minus pre-treatment, that coding implies a greater reduction for waitlist, opposite to the reported interpretation and the observed group means.
“To estimate a conditional latent change score model, the latent change score was regressed on a dummy variable representing treatment condition (1 = TBCT, 2 = waitlist).”
“Our primary hypothesis was corroborated, as treatment condition significantly predicted the latent change score (γ = -22.73,P < .01).This suggests that, on average, individuals in the TBCT condition experienced significantly greater reductions in social anxiety symptoms relative to waitlist control.”
Reported chi-square improvement does not match the two models
MinorSubtracting the new model's chi-square statistic of 2.40 from the original model's 12.95 gives 10.55, not the reported difference of 14.55. The corrected value would still support the stated P < .01 result for two degrees of freedom.
Reported 14.55 · recomputed 10.55
“A chi-square difference test comparing the two models was significant (χ 2 δ = 14.55, df = 2, P < .01),suggesting that the new model exhibits a significantly better fit than does the original model.”
Not every treatment effect size meets the paper's large-effect threshold
MinorThe paper defines a large effect as d = 0.80, but Table 2 reports a between-group FNE effect size of 0.60. Thus, the claim that all within- and between-group effect sizes were large is inconsistent with its own table.
“Consistent with established precedent (Cohen 1988), all of the within and between-group effect sizes were in the large range.”
“| FNE | 25.89 5.05 20.47 8.22 0.80 | 25.19 5.21 24.05 7.23 0.18 3.05 | 0.60 | | | | |”
Comorbidity count excludes eight participants
MinorThe analyzed sample contains 39 participants, and only 7 had GSAD alone, so 32-not 24-had at least one comorbid condition. Table 1 is consistent with 32: 24 had one comorbid disorder and 8 had two or more.
Reported 24 · recomputed 32
“Diagnostic interviews revealed that 24 participants had at least one additional comorbid condition, with depression being the most common additional diagnosis (n = 16).”
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Delavechia, T. R., Velasquez, M. L., Duran, É. P., Matsumoto, L. S., & Oliveira, I. R. D. (2016) · Archives of Clinical Psychiatry (São Paulo) · doi:10.1590/0101-60830000000078 · Cited by 16 · see citing works
de Oliveira, I. R. (2006) · European Review of Applied Psychology · doi:10.1016/j.erap.2006.01.002 · Cited by 14 · see citing works
"Measurement of Social-Evaluative Anxiety": Erratum.
Watson, D., & Friend, R. M. (1970) · Journal of Consulting and Clinical Psychology · doi:10.1037/h0020196 · Cited by 11
de Oliveira, I. R. (2014) · Routledge eBooks · doi:10.4324/9781315754918 · Cited by 10 · see citing works
Thompson, D., Cachelin, F., Striegel‐Moore, R. H., Barton, B., Shea, M., & Wilson, G. T. (2012) · International Journal of Eating Disorders · doi:10.1002/eat.22009 · Cited by 4 · see citing works
Combined Treatment for Social Anxiety Disorder
Rodebaugh, T. L., & Heimberg, R. G. (2005) · Journal of Cognitive Psychotherapy · doi:10.1891/088983905780907649
The impact social phobia on quality of life
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Flagged first, then by citations
Research works printed but not linked: 2
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Cited by
Sorted by citations
Neufeld, C. B., Palma, P. D. C., Caetano, K. A. D. S., Brust-Renck, P. G., Curtiss, J. E., & Hofmann, S. G. (2019) · International Journal of Clinical and Health Psychology · doi:10.1016/j.ijchp.2019.11.004 · Cited by 43 · see citing works
Self-citationHemanny, C., Carvalho, C., de Vasconcelos, N. S. S. M., Reis, D. M. L., Botelho, A. C., Bonavides, D., Seixas, C., & de Oliveira, I. R. (2019) · CNS Spectrums · doi:10.1017/s1092852919001457 · Cited by 22 · see citing works
Duran, É. P., Corchs, F., Vianna, A., Araújo, Á. C., Real, N. D., Silva, C., Ferreira, A. P., Francez, P. D. V., Godói, C., Silveira, H., et al. (2020) · CNS Spectrums · doi:10.1017/s1092852920001455 · Cited by 14 · see citing works
Duran, É. P., Hemanny, C., Vieira, R., Nascimento, O., Machado, L., de Oliveira, I. R., & Demarzo, M. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19020819 · Cited by 12 · see citing works
“A second study aiming to evaluate the efficacy of TBCT for generalized social anxiety disorder in a population with high rates of comorbid disorders, especially depression [33], was carried out.”
BackgroundHall, M., Luo, A., Bhullar, N., Moses, K., & Wootton, B. M. (2024) · Australian psychologist · doi:10.1080/00050067.2024.2356804 · Cited by 11 · see citing works
Hemanny, C., de Sena, E. P., & de Oliveira, I. R. (2021) · Journal of Clinical Pharmacy and Therapeutics · doi:10.1111/jcpt.13535 · Cited by 8 · see citing works
Rodrigues, E. P., Fechine, A. J. B., Oliveira, A. C., Matos, C. F. F., Passarela, C. D. M., Hemanny, C., Dias, F. D. M., Batista, J. W., Albuquerque, L. D. C. N., Soares, M. S., et al. (2023) · Trends in Psychiatry and Psychotherapy · doi:10.47626/2237-6089-2021-0247 · Cited by 6 · see citing works
“The TBCT protocol(27) was used to evaluate TBCT efficacy for generalized SAD compared to a waitlist condition in a sample with high rates of comorbid depression.(30) Reductions in social anxiety, social avoidance, and depression, all associated with a large effect size, were observed in the TBCT arm, whereas, no diffe…”
Santos, S. M. C. B., Huang, B., de Oliveira, I. R., & Demarzo, M. (2024) · MethodsX · doi:10.1016/j.mex.2024.103021 · Cited by 2 · see citing works
Hemanny, C., dos Santos, C. O., Moris, F. T. L., & Melnik, T. (2023) · Journal of Mood and Anxiety Disorders · doi:10.1016/j.xjmad.2023.100005 · Cited by 1 · see citing works
Widening the Reach of Cognitive Therapy with Trial-Based Cognitive Therapy Techniques
de Oliveira, I. R. (2024) · Springer eBooks · doi:10.1007/978-3-031-63494-9_7
- Authors
- Caetano, K. A. S., Depreeuw, B., Papenfuss, I., Curtiss, J., Langwerden, R. J., Hofmann, S. G., & Neufeld, C. B.
- Affiliations
- Boston University (US)
- Universidade de São Paulo (BR)
- Venue
- International Journal of Cognitive Therapy
- Published
- 2018-09
- Volume
- 11
- Issue
- 3
- Pages
- 325-342
- ISSN
- 1937-1209 (ISSN-L)
- 1937-1217
- OpenAlex
- W2893964253
- Cited by
- 11
- References
- 79
- Citations by year
- 2025: 1 · 2024: 3 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 1 · 2019: 2
- FWCI
- 1.31
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- International Journal of Cognitive Therapy (publishedVersion)
- OpenBU (Boston University) (acceptedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion, other-oa)
- OpenBU (Boston University) (submittedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Assessments
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- social anxiety disorder, generalized social anxiety disorder, comorbid depression, cognitive behavioral therapy, treatment efficacy, social avoidance, depressive symptoms
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-11.
Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-11.
Cited sources are checked by gpt-6-sol.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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