The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Changes in plasma hormones across the menstrual cycle in patients with menstrually related mood disorder and in control subjects
Abstract
A variety of hypotheses have been proposed to explain the premenstrual syndromes. These hypotheses serve as rationales for an equally diverse range of proposed treatments. To investigate these hypotheses, we obtained multiple blood samples across the menstrual cycle in women with well-characterized menstrually related mood disorder and in control subjects. No diagnosis-related differences were observed in the levels or patterns of secretion of progesterone, estradiol, follicle-stimulating hormone, luteinizing hormone, testosterone-estradiol-binding globulin, dehydroepiandrosterone sulfate, dihydrotestosterone, prolactin, or cortisol. Our data suggest that premenstrual syndrome does not represent a simple hormonal deficiency and that the cited rationales for several of the proposed treatments are of questionable merit.
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“Three other studies failed to detect any significant differences between cortisol patterns in healthy controls and PMS/PMDD patients [57, 66, 106].”
From Sleep, hormones, and circadian rhythms throughout the menstrual cycle in healthy women and women with premenstrual dysphoric disorder (2010) · cites this paper as [106]
Citations
Cites
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Premenstrual syndromes: overview from a methodologic perspective
Rubinow, D. R., & Roy‐Byrne, P. (1984) · American Journal of Psychiatry · doi:10.1176/ajp.141.2.163 · Cited by 223
Self-citationSERUM-PROLACTIN IN WOMEN WITI PREMENSTRUAL SYNDROME
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PROLACTIN LEVELS DURING THE MENSTRUAL CYCLE*
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TSH and prolactin responses to TRH in patients with premenstrual syndrome
Roy‐Byrne, P., Rubinow, D. R., Hoban, M. C., Grover, G. N., & Blank, D. U. (1987) · American Journal of Psychiatry · doi:10.1176/ajp.144.4.480 · Cited by 79
Self-citationMethyltestosterone with Imipramine in Men: Conversion of Depression to Paranoid Reaction
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Adrenal Function in Hirsutism. II. Effect of an Oral Contraceptive*
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Self-citationClinical trials in the premenstrual syndrome
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[Adrenal function in hirsutism].
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Premenstrual Syndromes: Past and Future Research Strategies
Rubinow, D. R., Hoban, C., Roy‐Byrne, P., Grover, G. N., & Post, R. M. (1985) · The Canadian Journal of Psychiatry · doi:10.1177/070674378503000703 · Cited by 31
Self-citationSerum prolactin in women with premenstrual syndrome.
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Cortisol Response to Dexamethasone in Women with Premenstrual Syndrome
Roy‐Byrne, P., Rubinow, D. R., Gwirtsman, H. E., Hoban, C., & Grover, G. N. (2008) · Neuropsychobiology · doi:10.1159/000118298 · Cited by 29
Self-citationProlactin levels in the premenstrual syndrome
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Cited by
Sorted by citations
Sex differences in anxiety and depression clinical perspectives
Altemus, M., Sarvaiya, N., & Neill Epperson, C. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2014.05.004 · Cited by 1,413
“Women with PMDD do not have abnormal levels of estrogen, progesterone, or other gonadal steroids across the cycle (Rubinow et al., 1988), but instead are more reactive to luteal phase progesterone in terms of both mood and physical symptoms (Schmidt et al.”
BackgroundEstrogen–serotonin interactions: implications for affective regulation
Rubinow, D. R., Schmidt, P. J., & Roca, C. A. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00162-0 · Cited by 501
Self-citationEpperson, C. N., Haga, K. K., Mason, G. F., Sellers, E. M., Gueorguieva, R. V., Zhang, W., Weiss, E. L., Rothman, D. L., & Krystal, J. H. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.9.851 · Cited by 402
Progesterone metabolite allopregnanolone in women with premenstrual syndrome
RAPKIN, A., MORGAN, M., GOLDMAN, L., BRANN, D., SIMONE, D., & MAHESH, V (1997) · Obstetrics & Gynecology · doi:10.1016/s0029-7844(97)00417-1 · Cited by 376
Premenstrual dysphoric disorder: Evidence for a new category for DSM-5
Epperson, C. N., Steiner, M., Hartlage, S. A., Eriksson, E., Schmidt, P. J., Jones, I., & Yonkers, K. A. (2012) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.11081302 · Cited by 361
Metadata
- Authors
- Rubinow, D. R., Hoban, M. C., Grover, G. N., Galloway, D. S., Roy-Byrne, P., Andersen, R., & Merriam, G. R.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Rubinow, David R.
- ORCID
- Rubinow, David R.
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 1988-01
- Volume
- 158
- Issue
- 1
- Pages
- 5-11
- ISSN
- 0002-9378 (ISSN-L)
- OpenAlex
- W2012067598
- Cited by
- 235
- References
- 18
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 5 · 2023: 3 · 2022: 1 · 2021: 3 · 2020: 3 · 2019: 4 · 2018: 2 · 2017: 7 · 2016: 5 · 2015: 3 · 2014: 6 · 2013: 9 · 2012: 15
- FWCI
- 8.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Obstetrics and Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Menstrual Health and Disorders
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Keywords
- premenstrual syndrome, menstrual cycle, plasma hormones, premenstrual dysphoric disorder, progesterone, estradiol, luteinizing hormone, follicle-stimulating hormone, testosterone, dehydroepiandrosterone sulfate, prolactin, cortisol, dihydrotestosterone
- MeSH terms
- Dehydroepiandrosterone, Estradiol, Female, Follicle Stimulating Hormone, Hormones, Humans, Hydrocortisone, Luteinizing Hormone, Menstrual Cycle, Premenstrual Syndrome, Prolactin, Sex Hormone-Binding Globulin, Dihydrotestosterone, Testosterone, Dehydroepiandrosterone Sulfate, Mood Disorders
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