The mechanical properties of human tibial trabecular bone as a function of metaphyseal location
Abstract
Experimental determination of the elastic modulus and ultimate strength of human tibial trabecular bone as a function of metaphyseal location is presented. A 1 cm cubic matrix with planes parallel to the subchondral plate was defined on five fresh frozen cadaver tibias. Approximately 400, 7 mm X 10 mm cylindrical bone plugs were cut from the locations defined by the matrix and tested in uniaxial compressive stress at a strain rate of 0.1%S-1. Results of the study indicate that the trabecular bone properties vary as much as two orders of magnitude from one location to another. As might be predicted from Wolff's law, and noted by previous investigators, concentrations of strength arise from the medial and lateral metaphyseal cortices toward the major medial and lateral contact regions. These results may be valuable for improved analytical modeling and optimal prosthetic design.
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Young's modulus can vary by as much as 100-fold within a single epiphysis.
“Young’s modulus can vary by as much as 100-fold, and strength as much as fivefold, within a single epiphysis (88).”
From Bone Mechanical Properties in Healthy and Diseased States (2018) · cites this paper as [88]
Strength can vary as much as fivefold within a single epiphysis.
“Young’s modulus can vary by as much as 100-fold, and strength as much as fivefold, within a single epiphysis (88).”
From Bone Mechanical Properties in Healthy and Diseased States (2018) · cites this paper as [88]
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“Material properties measured from uniaxial compressive testing of proximal tibial trabecular specimens taken from various locations can vary by up to two orders of magnitude (Goldstein et al., 1983).”
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“Properties have previously been shown to vary within anatomic location (Goldstein et al., 1983).”
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“[4] and Brown and Ferguson [5] respectively, compressive modulus can vary 100-fold from one location to another within a single proximal tibia, and strength can vary 5-fold within the proximal femur.”
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“With a maximum estimation of about 1.7 MPa maximum bone shear stresses, the Polyax system might ensure more reasonable safety margins.”
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Multiaxial Structure-Property Relations in Trabecular Bone
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“The actual value for the Young’s modulus of trabecular bone is quite variable depending on anatomic location (Goldstein et al., 1983; Goldstein, 1987), but it is certainly different from that of cortical bone (Choi et al., 1990).”
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“The predicted moduli for this tibia are of a similar order of magnitude to those reported in experimental studies [15].”
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A parametric analysis of fixation post shape in tibial knee prostheses
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Rapid prototyping technology for bone regeneration
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- Authors
- Goldstein, S. A., Wilson, D. L., Sonstegard, D. A., & Matthews, L. S.
- Affiliations
- University of Michigan (US)
- ORCID
- Goldstein, Steven A.
- Venue
- Journal of Biomechanics
- Publisher
- Elsevier BV
- Published
- 1983-01
- Volume
- 16
- Issue
- 12
- Pages
- 965-969
- ISSN
- 0021-9290 (ISSN-L)
- OpenAlex
- W2038929699
- Cited by
- 292
- References
- 29
- Citations by year
- 2026: 7 · 2025: 3 · 2024: 10 · 2023: 6 · 2022: 8 · 2021: 9 · 2020: 10 · 2019: 5 · 2018: 8 · 2017: 6 · 2016: 10 · 2015: 8 · 2014: 10 · 2013: 10 · 2012: 6
- FWCI
- 13.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Biomechanics (publishedVersion)
- PubMed (publishedVersion)
- Deep Blue (University of Michigan) (submittedVersion)
- Topics
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Health Sciences › Medicine › Epidemiology › Bone fractures and treatments
- Health Sciences › Medicine › Surgery › Orthopaedic implants and arthroplasty
- Keywords
- trabecular bone, tibia, elastic modulus, ultimate strength, uniaxial compression, bone mechanical properties, Wolff's law, cortical bone, bone plug, prosthesis design
- MeSH terms
- Aged, Biomechanical Phenomena, Cadaver, Female, Humans, Male, Middle Aged, Stress, Mechanical, Tibia
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