A general method applicable to the search for similarities in the amino acid sequence of two proteins

Evolving Genes and Proteins

Bryson, V., & Vogel, H. J. (1965) · Science · doi:10.1126/science.147.3653.68 · Cited by 1,343

The Amino Acid Sequence of Egg White Lysozyme

Canfield, R. E. (1963) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67888-3 · Cited by 739

The Sequence of Amino Acid Residues in Bovine Pancreatic Ribonuclease: Revisions and Confirmations

Smyth, D. G., Stein, W. H., & Moore, S. (1963) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)83984-4 · Cited by 567

Amino-Acid Sequence of Sperm Whale Myoglobin

Edmundson, A. B. (1965) · Nature · doi:10.1038/205883a0 · Cited by 396

Margaret O. Dayhoff: Atlas of Protein Sequence and Structure 1969 (Volume 4) XXIV u. 361 S., 21 Ausklapptafeln, 68 Abb. und zahlreiche Tabellen. National Biomedical Research Foundation, Silver Spring/Maryland 1969. Preis $ 12,50

Meisel, P. (1971) · Food / Nahrung · doi:10.1002/food.19710150234 · Cited by 346

An improved method of testing for evolutionary homology

Fitch, W. M. (1966) · Journal of Molecular Biology · doi:10.1016/s0022-2836(66)80258-9 · Cited by 313

Fine Structure of RNA Codewords Recognized by Bacterial, Amphibian, and Mammalian Transfer RNA

Marshall, R. E., Caskey, C. T., & Nirenberg, M. W. (1967) · Science · doi:10.1126/science.155.3764.820 · Cited by 147

The Structure of Human Hemoglobin

Konigsberg, W. H., & Hill, R. (1962) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50137-x · Cited by 115

The Structure of Human Hemoglobin

Konigsberg, W. H., Goldstein, J., & Hill, R. (1963) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67936-0 · Cited by 76

A Comparison of the Amino Acid Sequences of the Cytochrome c of Several Vertebrates.

Margoliash, E., Needleman, S. B., Stewart, J. W., & Takahashi, M. T. (1963) · Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · doi:10.3891/acta.chem.scand.17s-0250 · Cited by 25

RotaC: A web-based tool for the complete genome classification of group A rotaviruses

Maes, P., Matthijnssens, J., Rahman, M., & Ranst, M. A. V. (2009) · BMC Microbiology · doi:10.1186/1471-2180-9-238 · Cited by 401

The Molecular Defect Leading to Fabry Disease: Structure of Human α-Galactosidase

Garman, S. C., & Garboczi, D. N. (2004) · Journal of Molecular Biology · doi:10.1016/j.jmb.2004.01.035 · Cited by 400

Real-time selective sequencing using nanopore technology

Loose, M., Malla, S., & Stout, M. (2016) · Nature Methods · doi:10.1038/nmeth.3930 · Cited by 399

The Effects of Alignment Quality, Distance Calculation Method, Sequence Filtering, and Region on the Analysis of 16S rRNA Gene-Based Studies

Schloss, P. D. (2010) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000844 · Cited by 404

Deep learning in drug discovery: an integrative review and future challenges

Askr, H., Elgeldawi, E., Ella, H. A., Elshaier, Y. A. M. M., Gomaa, M. M., & Hassanien, A. E. (2022) · Artificial Intelligence Review · doi:10.1007/s10462-022-10306-1 · Cited by 428

Gibbs motif sampling: Detection of bacterial outer membrane protein repeats

Neuwald, A. F., Liu, J. S., & Lawrence, C. E. (1995) · Protein Science · doi:10.1002/pro.5560040820 · Cited by 392

Aligning amino acid sequences: Comparison of commonly used methods

Feng, D.-F., Johnson, M. S., & Doolittle, R. F. (1985) · Journal of Molecular Evolution · doi:10.1007/bf02100085 · Cited by 392

Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells.

Chang, C. C., Huh, H. Y., Cadigan, K. M., & Chang, T. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)36846-2 · Cited by 389

ampC cephalosporinase of Escherichia coli K-12 has a different evolutionary origin from that of beta-lactamases of the penicillinase type.

Jaurin, B., & Grundström, T. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.8.4897 · Cited by 390

Identification and Bioactivities of IFN-γ in Rainbow Trout Oncorhynchus mykiss : The First Th1-Type Cytokine Characterized Functionally in Fish

Zou, J., Carrington, A. C., Collet, B., Dijkstra, J. M., Yoshiura, Y., Bols, N. C., & Secombes, C. J. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.4.2484 · Cited by 386

The protein identification resource (PIR)

Sidman, K. E., George, D. G., Barker, W. C., & Hunt, L. T. (1988) · Nucleic Acids Research · doi:10.1093/nar/16.5.1869 · Cited by 386

A putative protein of a growth specific cDNA from BALB/C‐3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor

Tominaga, S. (1989) · FEBS Letters · doi:10.1016/0014-5793(89)81679-5 · Cited by 385

Characterization of the glycinin gene family in soybean.

Nielsen, N. C., Dickinson, C. D., Cho, T., Thanh, V. H., Scallon, B. J., Fischer, R. L., Sims, T. L., Drews, G., & Goldberg, R. B. (1989) · The Plant Cell · doi:10.1105/tpc.1.3.313 · Cited by 384

Boltzmann's principle, knowledge-based mean fields and protein folding. An approach to the computational determination of protein structures

Sippl, M. J. (1993) · Journal of Computer-Aided Molecular Design · doi:10.1007/bf02337562 · Cited by 385

Identification and mutational analysis of the immunodominant IgE binding epitopes of the major peanut allergen Ara h 2.

Stanley, J., King, N., Burks, A., Huang, S., Sampson, H. A., Cockrell, G., Helm, R., West, C., & Bannon, G. (1997) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1997.9998 · Cited by 402

Drosophila neuroglian: A member of the immunoglobulin superfamily with extensive homology to the vertebrate neural adhesion molecule L1

Bieber, A. J., Snow, P. M., Hortsch, M., Patel, N. H., Jacobs, J. R., Traquina, Z. R., Schilling, J., & Goodman, C. S. (1989) · Cell · doi:10.1016/0092-8674(89)90029-9 · Cited by 382

Algorithms for Finding Patterns in Strings

Aho, A. V. (1990) · Elsevier eBooks · doi:10.1016/b978-0-444-88071-0.50010-2 · Cited by 389

A brief history of bioinformatics

Gauthier, J., Vincent, A. T., Charette, S. J., & Derôme, N. (2018) · Briefings in Bioinformatics · doi:10.1093/bib/bby063 · Cited by 425

Human and Mouse Gene Structure: Comparative Analysis and Application to Exon PredictionPreprint

Batzoglou, S., Pachter, L. S., Mesirov, J. P., Berger, B., & Lander, E. S. (2000) · Genome Research · doi:10.1101/gr.10.7.950 · Cited by 386

Sequence Analysis with Stata

Brzinsky-Fay, C., Köhler, U., & Luniak, M. (2006) · The Stata Journal Promoting communications on statistics and Stata · doi:10.1177/1536867x0600600401 · Cited by 376

MUSTER: Improving protein sequence profile–profile alignments by using multiple sources of structure information

Wu, S., & Zhang, Y. (2008) · Proteins Structure Function and Bioinformatics · doi:10.1002/prot.21945 · Cited by 381

Dynalign: an algorithm for finding the secondary structure common to two RNA sequences

Mathews, D. H., & Turner, D. H. (2002) · Journal of Molecular Biology · doi:10.1006/jmbi.2001.5351 · Cited by 379

oPOSSUM: identification of over-represented transcription factor binding sites in co-expressed genes

Sui, S. J. H. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki624 · Cited by 370

The real cost of sequencing: scaling computation to keep pace with data generation

Muir, P., Li, S., Lou, S., Wang, D., Spakowicz, D. J., Salichos, L., Zhang, J., Weinstock, G. M., Isaacs, F. J., Rozowsky, J. S., et al. (2016) · Genome biology · doi:10.1186/s13059-016-0917-0 · Cited by 390

Assessing annotation transfer for genomics: quantifying the relations between protein sequence, structure and function through traditional and probabilistic scores

Wilson, C. A., Kreychman, J., & Gerstein, M. (2000) · Journal of Molecular Biology · doi:10.1006/jmbi.2000.3550 · Cited by 367

Sequence of an unusually large protein implicated in regulation of myosin activity in C. elegans

Benian, G. M., Kiff, J. E., Neckelmann, N., Moerman, D. G., & Waterston, R. (1989) · Nature · doi:10.1038/342045a0 · Cited by 367

Characterization and Cloning of a Receptor for BMP-2 and BMP-4 from NIH 3T3 Cells

Koenig, B. B., Cook, J. S., Wolsing, D. H., Ting, J., Tiesman, J. P., Correa, P. E., Olson, C. A., Pecquet, A. L., Ventura, F., Grant, R. A., et al. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.9.5961 · Cited by 366

Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past

PRICE, T. N., JACKSON, N. V., & HALESTRAP, P. A. (1998) · Biochemical Journal · doi:10.1042/bj3290321 · Cited by 361

Large-scale search for genes on which positive selection may operate

Endo, T., Ikeo, K., & Gojobori, T. (1996) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a025629 · Cited by 362

On the membrane topology of vertebrate cytochrome P-450 proteins.

Nelson, D. R., & Strobel, H. W. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)68746-0 · Cited by 362

Some biological sequence metrics

Waterman, M. S., Smith, T. F., & Beyer, W. A. (1976) · Advances in Mathematics · doi:10.1016/0001-8708(76)90202-4 · Cited by 361

Update on the aldehyde dehydrogenase gene (ALDH) superfamily

Jackson, B. C., Brocker, C. N., Thompson, D. C., Black, W., Vasiliou, K., Nebert, D. W., & Vasiliou, V. (2011) · Human Genomics · doi:10.1186/1479-7364-5-4-283 · Cited by 357

An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1

Collman, R. G., Balliet, J. W., Gregory, S. A., Friedman, H., Kolson, D. L., Nathanson, N., & Srinivasan, A. (1992) · Journal of Virology · doi:10.1128/jvi.66.12.7517-7521.1992 · Cited by 358

Genome Alignment, Evolution of Prokaryotic Genome Organization, and Prediction of Gene Function Using Genomic ContextPreprint

Wolf, Y. I., Rogozin, I. B., Kondrashov, A. S., & Koonin, E. V. (2001) · Genome Research · doi:10.1101/gr.gr-1619r · Cited by 357

A Survey on Similarity Measures in Text Mining

Vijaymeena, M. K., & Kavitha, K. (2016) · Machine Learning and Applications An International Journal · doi:10.5121/mlaij.2016.3103 · Cited by 355

Amino acid and cDNA sequences of a vascular endothelial cell mitogen that is homologous to platelet-derived growth factor.

Conn, G., BAYNE, M. L., Soderman, D. D., Kwok, P., Sullivan, K. A., Palisi, T. M., Hope, D. A., & Thomas, K. A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.7.2628 · Cited by 357

Recent progress in multiple sequence alignment: a survey

Notredame, C. (2002) · Pharmacogenomics · doi:10.1517/14622416.3.1.131 · Cited by 351

Parsimony, Phylogeny, and Genomics

Albert, V. A. (2006) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780199297306.001.0001 · Cited by 358

Glacial Survival of Boreal Trees in Northern Scandinavia

Parducci, L., Jørgensen, T., Tollefsrud, M. M., Elverland, E., Alm, T., Fontana, S. L., Bennett, K. D., Haile, J., Matetovici, I., Suyama, Y., et al. (2012) · Science · doi:10.1126/science.1216043 · Cited by 317

An Overview of Sequence Comparison: Time Warps, String Edits, and Macromolecules

Kruskal, J. B. (1983) · SIAM Review · doi:10.1137/1025045 · Cited by 352

Integrating Ambiguously Aligned Regions of DNA Sequences in Phylogenetic Analyses Without Violating Positional Homology

Lutzoni, F. M., Wagner, P. J., Reeb, V., & Zoller, S. (2000) · Systematic Biology · doi:10.1080/106351500750049743 · Cited by 352

Unsupervised Pattern Discovery in Speech

Park, A. S., & Glass, J. R. (2007) · IEEE Transactions on Audio Speech and Language Processing · doi:10.1109/tasl.2007.909282 · Cited by 351

Clustering Algorithms in Biomedical Research: A Review

Xu, R., & Wunsch, D. C. (2010) · IEEE Reviews in Biomedical Engineering · doi:10.1109/rbme.2010.2083647 · Cited by 367

[23] Progressive alignment and phylogenetic tree construction of protein sequences

Feng, D.-F., & Doolittle, R. F. (1990) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(90)83025-5 · Cited by 348

Basic Local Alignment Search Tool (BLAST)

Pevsner, J. (2009) · doi:10.1002/9780470451496.ch4 · Cited by 348

Bioinformatic challenges for DNA metabarcoding of plants and animals

Coissac, É., Riaz, T., & Puillandre, N. (2012) · Molecular Ecology · doi:10.1111/j.1365-294x.2012.05550.x · Cited by 376

Improvement of the GenTHREADER method for genomic fold recognition

McGuffin, L. J., & Jones, D. T. (2003) · Bioinformatics · doi:10.1093/bioinformatics/btg097 · Cited by 344

Automated structure prediction of weakly homologous proteins on a genomic scale

Zhang, Y., & Skolnick, J. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0305695101 · Cited by 344

Survival and Dormancy of Mycobacterium avium subsp. paratuberculosis in theEnvironment

Whittington, R. J., Marshall, D. J., Nicholls, P. J., Marsh, I. B., & Reddacliff, L. A. (2004) · Applied and Environmental Microbiology · doi:10.1128/aem.70.5.2989-3004.2004 · Cited by 360

Protein sequence similarity searches using patterns as seeds

Zhang, Z. (1998) · Nucleic Acids Research · doi:10.1093/nar/26.17.3986 · Cited by 343

Cascaded multiple classifiers for secondary structure prediction

Ouali, M., & King, R. D. (2000) · Protein Science · doi:10.1110/ps.9.6.1162 · Cited by 343

Topology fingerprint approach to the inverse protein folding problem

Godzik, A., Kolinski, A., & Skolnick, J. (1992) · Journal of Molecular Biology · doi:10.1016/0022-2836(92)90693-e · Cited by 339

cDNA Cloning and Expression of a Human Platelet-Derived Growth Factor (PDGF) Receptor Specific for B-Chain-Containing PDGF Molecules

Claesson, L., Eriksson, A. B., Morén, A., Severinsson, L., Ek, B., Östman, A., Betsholtz, C., & Heldin, C. (1988) · Molecular and Cellular Biology · doi:10.1128/mcb.8.8.3476 · Cited by 339

Time Warp Edit Distance with Stiffness Adjustment for Time Series Matching

Marteau, P.-F. (2009) · IEEE Transactions on Pattern Analysis and Machine Intelligence · doi:10.1109/tpami.2008.76 · Cited by 337

The active-site-serine penicillin-recognizing enzymes as members of the Streptomyces R61 dd -peptidase family

Joris, B., Ghuysen, J., Dive, G., Renard, A., Dideberg, O., Charlier, P., Frère, J., Kelly, J. A., Boyington, J. C., & Moews, P. C. (1988) · Biochemical Journal · doi:10.1042/bj2500313 · Cited by 333

SeqAn An efficient, generic C++ library for sequence analysis

Gogol‐Döring, A., Weese, D., Rausch, T., & Reinert, K. (2008) · BMC Bioinformatics · doi:10.1186/1471-2105-9-11 · Cited by 338

Nucleotide sequence of human endogenous retrovirus genome related to the mouse mammary tumor virus genome

Ono, M., Yasunaga, T., Miyata, T., & Ushikubo, H. (1986) · Journal of Virology · doi:10.1128/jvi.60.2.589-598.1986 · Cited by 332

A measure of the similarity of sets of sequences not requiring sequence alignment.

Blaisdell, B. (1986) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.83.14.5155 · Cited by 343

An HMM posterior decoder for sequence feature prediction that includes homology information

Käll, L., Krogh, A., & Sonnhammer, E. L. L. (2005) · Bioinformatics · doi:10.1093/bioinformatics/bti1014 · Cited by 328

Significant Improvement in Accuracy of Multiple Protein Sequence Alignments by Iterative Refinement as Assessed by Reference to Structural Alignments

Gotoh, O. (1996) · Journal of Molecular Biology · doi:10.1006/jmbi.1996.0679 · Cited by 328

Following Tetraploidy in Maize, a Short Deletion Mechanism Removed Genes Preferentially from One of the Two Homeologs

Woodhouse, M. R., Schnable, J. C., Pedersen, B. S., Lyons, E. H., Lisch, D. R., Subramaniam, S., & Freeling, M. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000409 · Cited by 338

Phylogenetic Networks: Concepts, Algorithms and Applications

Huson, D. H., Rupp, R., & Scornavacca, C. (2011) · Cited by 341

Nucleotide sequence and gene organization of sea urchin mitochondrial DNA

Jacobs, H. T., Elliott, D. J., Math, V. B., & Farquharson, A. J. (1988) · Journal of Molecular Biology · doi:10.1016/0022-2836(88)90452-4 · Cited by 319

Molecular definition and sequence motifs of the 52-kD component of human SS-A/Ro autoantigen.

Chan, E. K. L., Hamel, J. C., Buyon, J. P., & Tan, E. M. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115003 · Cited by 325

Effects of nucleotide sequence alignment on phylogeny estimation: a case study of 18S rDNAs of apicomplexa

Morrison, D. A., & Ellis, J. (1997) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a025779 · Cited by 325

A High-Throughput DNA Sequence Aligner for Microbial Ecology Studies

Schloss, P. D. (2009) · PLoS ONE · doi:10.1371/journal.pone.0008230 · Cited by 329

Ecological Patterns of nifH Genes in Four Terrestrial Climatic Zones Explored with Targeted Metagenomics Using FrameBot, a New Informatics Tool

Wang, Q., Quensen, J. F., Fish, J. A., Lee, T. K., Sun, Y., Tiedje, J. M., & Cole, J. R. (2013) · mBio · doi:10.1128/mbio.00592-13 · Cited by 323

Pattern recognition in nucleic acid sequences. I. A general method for finding local homologies and symmetries

Goad, W. B., & Kanehisa, M. I. (1982) · Nucleic Acids Research · doi:10.1093/nar/10.1.247 · Cited by 323

Significant and persistent impact of timber harvesting on soil microbial communities in Northern coniferous forests

Hartmann, M., Howes, C. G., VanInsberghe, D., Yu, H., Bachar, D., Christen, R., Nilsson, R. H., Hallam, S., & Mohn, W. W. (2012) · The ISME Journal · doi:10.1038/ismej.2012.84 · Cited by 322

PROTEIN FAMILIES AND THEIR EVOLUTION—A STRUCTURAL PERSPECTIVE

Orengo, C. A., & Thornton, J. M. (2005) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.74.082803.133029 · Cited by 328

Expression of specific mRNAs during adipose differentiation: identification of an mRNA encoding a homologue of myelin P2 protein.

Bernlohr, D., Angus, C., Lane, M. D., Bolanowski, M. A., & Kelly, T. J. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.17.5468 · Cited by 320

The 3' conserved segment of integrons contains a gene associated with multidrug resistance to antiseptics and disinfectants

Paulsen, I. T., Littlejohn, T. G., Rådström, P., Sundström, L., Sköld, O., Swedberg, G., & Skurray, R. A. (1993) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.37.4.761 · Cited by 320

Database algorithm for generating protein backbone and side-chain co-ordinates from a Cα trace

Holm, L., & Sander, C. (1991) · Journal of Molecular Biology · doi:10.1016/0022-2836(91)90883-8 · Cited by 321

Complete amino acid sequence of an HLA-DR antigen-like beta chain as predicted from the nucleotide sequence: similarities with immunoglobulins and HLA-A, -B, and -C antigens.

Larhammar, D., Schenning, L., Gustafsson, K. T., Wiman, K. G., Claesson, L., Rask, L., & Peterson, P. A. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.12.3687 · Cited by 320

3DCoffee: Combining Protein Sequences and Structures within Multiple Sequence Alignments

O’Sullivan, Ó., Suhre, K., Abergel, C., Higgins, D. G., & Notredame, C. (2004) · Journal of Molecular Biology · doi:10.1016/j.jmb.2004.04.058 · Cited by 318

Salmonella enterica genomes from victims of a major sixteenth-century epidemic in Mexico

Vågene‬, Å. J., Herbig, A., Campana, M. G., García, N. M. R., Warinner, C., Sabin, S. J., Spyrou, M. A., Valtueña, A. A., Huson, D. H., Tuross, N., et al. (2018) · Nature Ecology & Evolution · doi:10.1038/s41559-017-0446-6 · Cited by 324

Complete Nucleotide Sequence of the Drosophila Transposable Element Copia: Homology Between Copia and Retroviral Proteins

Mount, S. M., & Rubin, G. M. (1985) · Molecular and Cellular Biology · doi:10.1128/mcb.5.7.1630-1638.1985 · Cited by 317

A flexible motif search technique based on generalized profiles

Bücher, P., Karplus, K. J., Moeri, N., & Hofmann, K. (1996) · Computers & Chemistry · doi:10.1016/s0097-8485(96)80003-9 · Cited by 316

Identification of five different insulin-like growth factor binding proteins (IGFBPs) from adult rat serum and molecular cloning of a novel IGFBP-5 in rat and human

Shimasaki, S., Shimonaka, M., Zhang, H. P., & LING, N. C. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)99272-0 · Cited by 313

Inferring and perturbing cell fate regulomes in human brain organoids

Fleck, J. S., Jansen, S. M. J., Wollny, D., Zenk, F., Seimiya, M., Jain, A., Okamoto, R., Santel, M., He, Z., Camp, J. G., et al. (2023) · Nature · doi:10.1038/s41586-022-05279-8 · Cited by 315

Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein

Prior, P. P., Schmitt, B., Grenningloh, G., Pribilla, I., Multhaup, G., Beyreuther, K. T., Maulet, Y., Werner, P., Langosch, D., Kirsch, J., et al. (1992) · Neuron · doi:10.1016/0896-6273(92)90136-2 · Cited by 320

A novel capacitative calcium entry channel expressed in excitable cells

Philipp, S. E., Hambrecht, J., Braslavski, L., Schroth, G., Freichel, M., Murakami, M., Cavalié, A., & Flockerzi, V. (1998) · The EMBO Journal · doi:10.1093/emboj/17.15.4274 · Cited by 308

Phylogeny of five fungus-like protoctistan Phytophthora species, inferred from the internal transcribed spacers of ribosomal DNA.

Lee, S. B., & Taylor, J. W. (1992) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040750 · Cited by 311

Conservation of sequences of subunits of mitochondrial complex I and their relationships with other proteins

Fearnley, I. M., & Walker, J. E. (1992) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/0005-2728(92)90001-i · Cited by 308

hnRNP 1, the polyprimidine tract-binding protein: distinct nuclear localization and association with hnRNAs

Ghetti, A., Piñol-Roma, S., Michael, W. M., Morandi, C., & Dreyfuss, G. (1992) · Nucleic Acids Research · doi:10.1093/nar/20.14.3671 · Cited by 311

Evolution Of Class-I MHC Genes And Proteins: From Natural Selection To Thymic Selection

Lawlor, D. A., Zemmour, J., Ennis, P. D., & Parham, P. (1990) · Annual Review of Immunology · doi:10.1146/annurev.iy.08.040190.000323 · Cited by 315

Small intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders

Saffouri, G. B., Shields‐Cutler, R. R., Chen, J., Yang, Y., Lekatz, H. R., Hale, V. L., Cho, J. M., Battaglioli, E. J., Bhattarai, Y., Thompson, K. J., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-09964-7 · Cited by 318

An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type I and type II murine macrophage scavenger receptors.

Freeman, M. W., Ashkenas, J., Rees, D. J. G., Kingsley, D. M., Copeland, N. G., Jenkins, N. A., & Krieger, M. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.22.8810 · Cited by 309

Trp12, a novel Trp related protein from kidney

Wissenbach, U., Bödding, M., Freichel, M., & Flockerzi, V. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)02212-2 · Cited by 309

Carnivore diet analysis based on next‐generation sequencing: application to the leopard cat (Prionailurus bengalensis) in Pakistan

Shehzad, W., Riaz, T., Nawaz, M. A., Miquel, C., POILLOT, C., Shah, S. A., Pompanon, F., Coissac, É., & Taberlet, P. (2012) · Molecular Ecology · doi:10.1111/j.1365-294x.2011.05424.x · Cited by 304

Isolation and characterization of human colonic bacteria able to hydrolyse chlorogenic acid

Couteau, D., McCartney, A. L., Gibson, G. R., Williamson, G., & Faulds, C. B. (2001) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2001.01316.x · Cited by 305

Long walk to genomics: History and current approaches to genome sequencing and assembly

Giani, A. M., Gallo, G. R., Gianfranceschi, L., & Formenti, G. (2019) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2019.11.002 · Cited by 338

Amino acid substitutions in structurally related proteins a pattern recognition approach

Risler, J., Delorme, M.-O., Delacroix, H., & Hénaut, A. (1988) · Journal of Molecular Biology · doi:10.1016/0022-2836(88)90058-7 · Cited by 305

Pcons: A neural‐network–based consensus predictor that improves fold recognition

Lundström, J., Rychlewski, L., Bujnicki, J. M., & Elofsson, A. (2001) · Protein Science · doi:10.1110/ps.08501 · Cited by 304

Discoverer: automatic protocol reverse engineering from network traces

Cui, W., Kannan, J., & Wang, H. J. (2007) · Cited by 304

Comparative analysis of the small RNA transcriptomes of Pinus contorta and Oryza sativaPreprint

Morin, R. D., Aksay, G., Dolgosheina, E. V., Ebhardt, H. A., Magrini, V. J., Mardis, E. R., Şahinalp, S. C., & Unrau, P. J. (2008) · Genome Research · doi:10.1101/gr.6897308 · Cited by 304

SeqTrace: A Graphical Tool for Rapidly Processing DNA Sequencing Chromatograms

Stucky, B. J. (2012) · Journal of Biomolecular Techniques JBT · doi:10.7171/jbt.12-2303-004 · Cited by 303

ESPRIT: estimating species richness using large collections of 16S rRNA pyrosequences

Sun, Y., Cai, Y., Liu, L., Yu, F., Farrell, M. L., McKendree, W., & Farmerie, W. G. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp285 · Cited by 303

Early events in Epstein-Barr virus infection of human B lymphocytes

Alfieri, C., Birkenbach, M. P., & Kieff, E. D. (1991) · Virology · doi:10.1016/0042-6822(91)90893-g · Cited by 303

Approaches to the Automatic Discovery of Patterns in Biosequences

Brāzma, A., Jonassen, I., Eidhammer, I., & Gilbert, D. (1998) · Journal of Computational Biology · doi:10.1089/cmb.1998.5.279 · Cited by 303

DNA sequence comparison based on amino acid similarity

Hiraoka, S., & Nagai, K. (1995) · doi:10.11234/gi1990.6.152

A method for detecting distant evolutionary relationships between protein or nucleic acid sequences in the presence of deletions or insertions

ELLEMAN, T. C. (1978) · Journal of Molecular Evolution · doi:10.1007/bf01733890 · Cited by 9

An improved method of testing for evolutionary homology

Fitch, W. M. (1966) · Journal of Molecular Biology · doi:10.1016/s0022-2836(66)80258-9 · Cited by 313

The theory and computation of evolutionary distances: Pattern recognition

Sellers, P. H. (1980) · Journal of Algorithms · doi:10.1016/0196-6774(80)90016-4 · Cited by 372

Finding Sequence Similarities

Mushegian, A. R. (2007) · Elsevier eBooks · doi:10.1016/b978-012088794-1/50002-1 · Cited by 1