Naloxone reduces cigarette smoking
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The endogenous opioid system plays a strong role in the development of addiction to every class of drug.
“While opiate drugs are themselves strongly addictive, the role of the endogenous opioid system in addiction is not limited to these, as this system plays a strong role in the development of addiction to every class of drug (Altshuler et al 1980; Karras and Kane 1980; De Vry et al 1989; Kuzmin et al 1997; Ismayilova and Shoaib 2010; for a review see van Ree et al, 1999).”
From The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction (2012) · cites this paper as Karras and Kane 1980
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SPECIFIC RADIOIMMUNOASSAY OF HUMAN β-ENDORPHIN IN UNEXTRACTED PLASMA.*
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Neural mechanisms underlying nicotine addiction: acute positive reinforcement and withdrawal
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“1980 ; Karras and Kane 1980 ; De Vry et al .”
Nicotine Gateway Effects on Adolescent Substance Use
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- Authors
- Karras, A., & Kane, J. M.
- Affiliations
- Long Island Jewish Medical Center (US)
- Corresponding author
- Karras, A.
- ORCID
- Kane, J.M.
- Venue
- Life Sciences
- Publisher
- Elsevier BV
- Published
- 1980-10
- Volume
- 27
- Issue
- 17
- Pages
- 1541-1545
- ISSN
- 0024-3205 (ISSN-L)
- OpenAlex
- W2004215190
- Cited by
- 144
- References
- 20
- Citations by year
- 2024: 1 · 2022: 1 · 2019: 3 · 2017: 1 · 2016: 1 · 2015: 1 · 2014: 1 · 2013: 3 · 2012: 3
- FWCI
- 3.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Life Sciences (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- naloxone, cigarette smoking, smoking reduction, beta-endorphin, nicotine dependence, positive reinforcement, opioid antagonists, withdrawal syndrome, ACTH, corticosteroids, chronic smokers
- MeSH terms
- Adult, Clinical Trials as Topic, Double-Blind Method, Female, Humans, Male, Middle Aged, Naloxone, Placebos, Smoking
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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