The relation of recombination to mutational advance
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Natural selection is less efficient in this setting, and Muller's Ratchet can lead to the accumulation of slightly deleterious mutations.
“Natural selection is less efficient in this setting, and Muller's Ratchet can lead to the accumulation of slightly deleterious mutations (Muller 1964).”
From RELAX: Detecting Relaxed Selection in a Phylogenetic Framework (2015) · cites this paper as Muller 1964
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- Authors
- Muller, H. J.
- Affiliations
- Indiana University Bloomington (US)
- Corresponding author
- Muller, H.J.
- Venue
- Mutation Research
- Publisher
- Elsevier BV
- Published
- 1964-05
- Volume
- 1
- Issue
- 1
- Pages
- 2-9
- ISSN
- 0027-5107 (ISSN-L)
- OpenAlex
- W2045716211
- Cited by
- 2,512
- References
- 0
- Citations by year
- 2026: 72 · 2025: 68 · 2024: 71 · 2023: 97 · 2022: 104 · 2021: 98 · 2020: 92 · 2019: 90 · 2018: 97 · 2017: 75 · 2016: 103 · 2015: 97 · 2014: 92 · 2013: 89 · 2012: 93
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Mutation research. Fundamental and molecular mechanisms of mutagenesis (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Social Sciences › Cultural Studies › Language and cultural evolution
- Social Sciences › Arts and Humanities › History and Philosophy of Science › Philosophy and History of Science
- Keywords
- recombination, synergistic effect, linkage, outbreeding, sexual reproduction, mutation-selection balance, ratchet mechanism, genetic drift, asexual populations
- MeSH terms
- Genes, Mutation, Recombination, Genetic, Research
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