The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice.
Abstract
We generated a novel strain of mutant mouse with a deletion in the gene encoding metabotropic glutamate receptor 1 (mGluR1). Gross anatomy of the hippocampus, excitatory synaptic transmission, long-term depression, and short-term potentiation in the hippocampal CA1 region are all apparently normal in the mutant mice. In contrast, long-term potentiation (LTP) is substantially reduced, and a moderate level of impairment is observed in context-specific associative learning. We propose that mGluR1 is not "in line" in LTP production, but rather modulates the plasticity process, and hence affects context-specific associative learning.
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“It is important to point out that the only exceptional case, namely that of the mGluR1 mutant mice, is complicated by the fact that two groups have generated and analyzed these mutants independently and have obtained opposing results (Aiba et al., 1994; Conquet et al., 1994; Chen and Tonegawa, 1997).”
From The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. (1996) · cites this paper as Aiba et al., 1994
In the citing paper
“Numerous studies, using lesioning (Kim and Fanselow, 1992;Phillips and LeDoux, 1992) and genetic (Aiba et al., 1994;Tsien et al., 1996) strategies, indicated that the hippocampus plays a crucial role in context-dependent fear conditioning.”
From Modulation of learning and anxiety by corticotropin-releasing factor (CRF) and stress: differential roles of CRF receptors 1 and 2 (1999) · cites this paper as Aiba et al., 1994
Citations
Cites
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction
Chomczynski, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1006/abio.1987.9999 · Cited by 65,515
Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans.
Squire, L. R. (1992) · Psychological Review · doi:10.1037/0033-295x.99.2.195 · Cited by 5,376
Morris, R. G. M., Anderson, E., Lynch, G. S., & Baudry, M. (1986) · Nature · doi:10.1038/319774a0 · Cited by 3,640
Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning.
Phillips, R. G., & LeDoux, J. E. (1992) · Behavioral Neuroscience · doi:10.1037/0735-7044.106.2.274 · Cited by 3,292
Molecular diversity of glutamate receptors and implications for brain function
Nakanishi, S. (1992) · Science · doi:10.1126/science.1329206 · Cited by 2,543
Modality-Specific Retrograde Amnesia of Fear
Kim, J. J., & Fanselow, M. S. (1992) · Science · doi:10.1126/science.1585183 · Cited by 2,483
Dudek, S. M., & Bear, M. F. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.10.4363 · Cited by 1,708
Deficient Hippocampal Long-Term Potentiation in α-Calcium-Calmodulin Kinase II Mutant Mice
Silva, A. J., Stevens, C. F., Tonegawa, S., & Wang, Y. (1992) · Science · doi:10.1126/science.1378648 · Cited by 1,472
Impaired Spatial Learning in α-Calcium-Calmodulin Kinase II Mutant Mice
Silva, A. J., Paylor, R. E., Wehner, J. M., & Tonegawa, S. (1992) · Science · doi:10.1126/science.1321493 · Cited by 1,366
Sequence and expression of a metabotropic glutamate receptor
Masu, M., Tanabe, Y., Tsuchida, K., Shigemoto, R., & Nakanishi, S. (1991) · Nature · doi:10.1038/349760a0 · Cited by 1,216
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Metadata
- Authors
- Aiba, A.
- Affiliations
- Howard Hughes Medical Institute (US)
- Corresponding author
- Aiba, A
- ORCID
- Aiba, A
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 1994-10-21
- Volume
- 79
- Issue
- 2
- Pages
- 365-375
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W1983956991
- Cited by
- 614
- References
- 49
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 1 · 2023: 7 · 2022: 10 · 2021: 13 · 2020: 14 · 2019: 11 · 2018: 5 · 2017: 9 · 2016: 14 · 2015: 14 · 2014: 13 · 2013: 12 · 2012: 21
- FWCI
- 16.15
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cell (publishedVersion)
- PubMed (publishedVersion)
- Rare & Special e-Zone (The Hong Kong University of Science and Technology) (submittedVersion)
- Funders
- National Institute of Neurological Disorders and Stroke (R01 NS32925, R01NS020591, NS20591, R01NS032925)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Keywords
- metabotropic glutamate receptor 1, hippocampal long-term potentiation, hippocampal CA1, synaptic plasticity, long-term depression, short-term potentiation, excitatory synaptic transmission, learning disabilities
- MeSH terms
- Animals, Base Sequence, Electric Stimulation, Female, Genes, Hippocampus, Male, Mice, Inbred C57BL, Molecular Sequence Data, Synaptic Transmission, Neuronal Plasticity, Restriction Mapping, Receptors, Glutamate, Long-Term Potentiation, DNA Primers, Mice, Knockout, Mice, In Vitro Techniques
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