CoChat
Sign Up
Cited by 922Helicobacter pylori-related gastroenterology studiesGastrointestinal Bleeding Diagnosis and TreatmentHepatitis C virus research

The DOI matches its Crossref record; 22 of the 23 references it cites were found in a registry or an index.

Cure of duodenal ulcer associated with eradication of Helicobacter pylori

Rauws, E.A.J., Tytgat, G.N.J.·1990·The Lancet
DOI 10.1016/0140-6736(90)91301-p
Open this paper in CoChat — free account

Abstract

50 patients with intractable duodenal ulcer were randomly assigned to 4 weeks of treatment with colloidal bismuth subcitrate (CBS) alone (26 patients) or with amoxicillin and metronidazole (24 patients). 5 patients (all on triple therapy) withdrew because of side-effects. In 17 of the 45 patients who completed the treatment, Helicobacter pylori was eradicated, and there was no ulcer relapse during the first 12 months of follow-up. The ulcer relapse rate was significantly higher (17 of 21 [89%]) among patients who remained positive for H pylori. 9 patients who remained positive for H pylori and had ulcer relapses within 6 months of treatment with CBS alone, were subsequently given triple therapy. 7 of the 9 showed H pylori eradication and no relapses within the next 12 months. The 2 patients still H pylori-positive after triple therapy had further ulcer relapses. H pylori eradication, without altering acid output, will become the mainstay of duodenal ulcer treatment because it cures the disease.

Overview

Integrity signals

Registry

Crossref · 10.1016/0140-6736(90)91301-p

Cites

22 of 22 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 23 references

Research works printed but not linked: 3

  1. Lambert, 1987, Effect of colloiad bismuth (De-Nol) and healing relapse of duodenal ulcer-role of Campylobacter pyloridis., Gastroenterology, 92, 1489
  2. Borody, 1988, Long term Campylobacter pylori recurrence post-eradication, Gastroenterology, 94, 43
  3. Smith, 1988, A comparison of ranitidine and tripotassium dicitrato-bismuth (TDB) in relapse rate of duodenal ulcer. The role of Campylobacter pylori, Gastroenterology, 94, 431

Cited by

Sorted by citations

Items 601–700 of 908

Related

See all

Metadata

Authors
Rauws, E. A. J., & Tytgat, G. N. J.
Affiliations
Amsterdam UMC Location University of Amsterdam (NL)
Corresponding author
Rauws, E.A.J.
Venue
The Lancet
Publisher
Elsevier BV
Published
1990-05
Volume
335
Issue
8700
Pages
1233-1235
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
DOI
10.1016/0140-6736(90)91301-p
OpenAlex
W2029865847
Cited by
922
References
23
Citations by year
2026: 2 · 2025: 5 · 2024: 5 · 2023: 4 · 2022: 4 · 2021: 2 · 2020: 5 · 2019: 6 · 2018: 6 · 2017: 12 · 2016: 13 · 2015: 10 · 2014: 18 · 2013: 11 · 2012: 14
FWCI
106.47
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • The Lancet (publishedVersion)
  • PubMed (publishedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
  • Pure Amsterdam UMC (submittedVersion)
Topics
  • Health Sciences › Medicine › Gastroenterology › Helicobacter pylori-related gastroenterology studies
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal Bleeding Diagnosis and Treatment
  • Health Sciences › Medicine › Hepatology › Hepatitis C virus research
Keywords
duodenal ulcer, Helicobacter pylori eradication, bismuth subcitrate, amoxicillin, metronidazole, triple therapy, ulcer recurrence
MeSH terms
Administration, Oral, Amoxicillin, Anti-Ulcer Agents, Campylobacter, Campylobacter Infections, Drug Administration Schedule, Drug Evaluation, Drug Therapy, Combination, Duodenal Ulcer, Follow-Up Studies, Gastric Mucosa, Humans, Metronidazole, Organometallic Compounds, Prospective Studies, Recurrence, Randomized Controlled Trials as Topic

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review