Skin conductance: A potentially sensitive test for depression

Ward, Nicholas G.; Doerr, Hans O.; Storrie, Michael C.

doi:10.1016/0165-1781(83)90076-8

Cited by 79Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesTreatment of Major DepressionStress Responses and Cortisol

Skin conductance: A potentially sensitive test for depression

Ward, Nicholas G., Doerr, Hans O., Storrie, Michael C.·1983·Psychiatry Research

DOI 10.1016/0165-1781(83)90076-8

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Abstract

The mean resting skin conductance level (SCL) in 31 inpatients with major unipolar depression was 2.63 mumho/cm2 +/- SD 1.41 compared to 7.81 mumho/cm2 +/- SD 3.0 in the control group. The best criterion below which an SCL could be considered abnormal was 4.3 mumho/cm2 with a resulting sensitivity of 87% and specificity of 89%. There was a significant difference in SCL between males and females but none between drug-free and medicated patients. SCL was abnormal in all depression subtypes. The SCL may represent a biological final common pathway in depression and may prove to be a very effective diagnostic test for depression.

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Some studies have shown that finger-based SC are reduced for patients with depression measured in a short-term lab study.
“Some studies have shown that finger-based SC are reduced for patients with depression measured in a short-term lab study [57-59].”
From Identifying Objective Physiological Markers and Modifiable Behaviors for Self-Reported Stress and Mental Health Status Using Wearable Sensors and Mobile Phones: Observational Study (2018) · cites this paper as [57]
Heart rate variability has been found to be consistently lower in patients with psychiatric disorders.
“Other promising biomarkers from wearable devices are heart rate variability, which has been found to be consistently lower in patients with psychiatric disorders, electrodermal activity, and skin conductance [36,37].”
From Predicting Depression From Smartphone Behavioral Markers Using Machine Learning Methods, Hyperparameter Optimization, and Feature Importance Analysis: Exploratory Study (2021) · cites this paper as [37]

An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032 · see citing works
A rating scale for depression
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817 · see citing works
Diagnostic criteria for use in psychiatric research.
Feighner, J. P., Robins, E., Guze, S. B., Woodruff, R. A., Winokur, G., & Munoz, R. A. (1972) · Archives of General Psychiatry · doi:10.1001/archpsyc.1972.01750190059011 · Cited by 5,491 · see citing works
A Specific Laboratory Test for the Diagnosis of Melancholia: Standardization, Validation, and Clinical Utility
Carroll, B. J. (1981) · Archives of General Psychiatry · doi:10.1001/archpsyc.1981.01780260017001 · Cited by 2,243 · see citing works
Publication Recommendations for Electrodermal Measurements
Fowles, D. C., Christie, M. J., Edelberg, R., Grings, W. W., Lykken, D. T., & Venables, P. H. (1981) · Psychophysiology · doi:10.1111/j.1469-8986.1981.tb03024.x · Cited by 1,700 · see citing works
DIRECT MEASUREMENT OF SKIN CONDUCTANCE: A PROPOSAL FOR STANDARDIZATION
Lykken, D. T., & Venables, P. H. (1971) · Psychophysiology · doi:10.1111/j.1469-8986.1971.tb00501.x · Cited by 988 · see citing works
Affective Disorders in a US Urban Community
Weissman, M. M. (1978) · Archives of General Psychiatry · doi:10.1001/archpsyc.1978.01770350030002 · Cited by 648 · see citing works
Overview of Recent Research in Depression
Akiskal, H. S. (1975) · Archives of General Psychiatry · doi:10.1001/archpsyc.1975.01760210019001 · Cited by 548 · see citing works
Bimodality and lateral asymmetry of skin conductance orienting activity in schizophrenics: replication and evidence of lateral asymmetry in patients with depression and disorders of personality.
Gruzelier, J. H., & Venables, P. H. (1974) · PubMed · Cited by 216 · see citing works
Faster Cholinergic REM Sleep Induction in Euthymic Patients with Primary Affective Illness
Sitaram, N., Nürnberger, J. I., Gershon, E. S., & Gillin, J. C. (1980) · Science · doi:10.1126/science.7361118 · Cited by 194 · see citing works
Physiological measures in agitated and retarded depressed patients
Lader, M. H., & Wing, L. (1969) · Journal of Psychiatric Research · doi:10.1016/0022-3956(69)90014-4 · Cited by 136 · see citing works
Electrodermal Activity in Euthymic Unipolar and Bipolar Affective Disorders
Iacono, W. G. (1983) · Archives of General Psychiatry · doi:10.1001/archpsyc.1983.01790050083010 · Cited by 121 · see citing works
Autonomic Correlates of Depression and Clinical Improvement Following Electroconvulsive Shock Therapy
Dawson, M. E., Schell, A. M., & Catania, J. J. (1977) · Psychophysiology · doi:10.1111/j.1469-8986.1977.tb01201.x · Cited by 109 · see citing works
Changes in Mood and Autonomic Functioning During the Menstrual Cycle
Little, B. C., & Zahn, T. P. (1974) · Psychophysiology · doi:10.1111/j.1469-8986.1974.tb01118.x · Cited by 93 · see citing works
ECCRINE SWEAT GLAND ACTIVITY AND RACIAL DIFFERENCES IN RESTING SKIN CONDUCTANCE
Johnson, L. C., & Landon, M. M. (1965) · Psychophysiology · doi:10.1111/j.1469-8986.1965.tb03264.x · Cited by 71 · see citing works
Electrodermal Activity in Depression: Clinical and Biochemical Correlates
Mirkin, A. M., & Coppen, A. J. (1980) · The British Journal of Psychiatry · doi:10.1192/bjp.137.1.93 · Cited by 67 · see citing works
Bilateral Skin Conductance and Skin Potential in Schizophrenic and Normal Subjects: The Identification of the Fast Habituator Group of Schizophrenics
Patterson, T., & Venables, P. H. (1978) · Psychophysiology · doi:10.1111/j.1469-8986.1978.tb03109.x · Cited by 49 · see citing works
The symptomatic correlates of the skin conductance changes in depression
Noble, P., & LADER, M. H. (1971) · Journal of Psychiatric Research · doi:10.1016/0022-3956(71)90008-2 · Cited by 44 · see citing works
Skin Conductance Characteristics of Depressed Subjects Before and After Therapeutic Intervention
Storrie, M. C., Doerr, H. O., & Johnson, M. H. (1981) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-198103000-00004 · Cited by 43 · see citing works
Self-citation
Electrodermal activity in the affective disorders and schizophrenia
Toone, B., Cooke, E., & LADER, M. H. (1981) · Psychological Medicine · doi:10.1017/s0033291700052818 · Cited by 39 · see citing works
THE RELATIONSHIP BETWEEN PHYSIOLOGICAL AND PSYCHOLOGICAL RESPONSIVITY
Greenfield, N. S., KATZ, D., ALEXANDER, A. A., & Roessler, R. (1963) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-196306000-00004 · Cited by 36 · see citing works
Electrodermal Reactivity: An Analysis by Age and Sex
Eisdorfer, C., Doerr, H. O., & Follette, W. C. (1980) · Journal of Human Stress · doi:10.1080/0097840x.1980.9936107 · Cited by 34 · see citing works
Self-citation
Race and examiner as significant influences on basal skin impedance.
Bernstein, A. S. (1965) · Journal of Personality and Social Psychology · doi:10.1037/h0021747 · Cited by 30 · see citing works
A Psychophysiological Distinction between Types of Depressive States
Byrne, D. G. (1975) · Australian & New Zealand Journal of Psychiatry · doi:10.3109/00048677509159846 · Cited by 29 · see citing works
The thyrotropin releasing hormone stimulation test: a review.
Sternbach, H. A., Rh, G., & Gwirtsman, H. E. (1982) · PubMed · Cited by 19 · see citing works
Clinical correlates of the TRH infusion test in primary depression.
Kirstein, L., Gold, M. S., Extein, I., Martin, D., & Pottash, A. L. C. (1982) · PubMed · Cited by 14 · see citing works
Clinical Laboratory and Diagnostic Testing
Rosse, R. B. (1990) · Journal of Neuropsychiatry · doi:10.1176/jnp.2.4.450 · Cited by 7 · see citing works

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“Some studies have shown that finger-based SC are reduced for patients with depression measured in a short-term lab study [57-59].”
Background
The association between electrodermal activity (EDA), depression and suicidal behaviour: A systematic review and narrative synthesis
Sarchiapone, M., Gramaglia, C. M., Iosue, M., Carli, V., Mandelli, L., Serretti, A., Marangon, D., & Zeppegno, P. (2018) · BMC Psychiatry · doi:10.1186/s12888-017-1551-4 · Cited by 197 · see citing works
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Opoku Asare, K., Terhorst, Y., Vega, J., Peltonen, E., Lagerspetz, E., & Ferreira, D. (2021) · JMIR mHealth and uHealth · doi:10.2196/26540 · Cited by 145 · see citing works
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Lee, S., Kim, H., Park, M. J., & Jeon, H. J. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.672347 · Cited by 117 · see citing works
Objective assessment of depressive symptoms with machine learning and wearable sensors data
Ghandeharioun, A., Fedor, S., Sangermano, L., Ionescu, D., Alpert, J., Dale, C., Sontag, D., & Picard, R. (2017) · 2017 Seventh International Conference on Affective Computing and Intelligent Interaction (ACII) · doi:10.1109/acii.2017.8273620 · Cited by 116 · see citing works
Contextualizing the neurobiology of conduct disorder in an emotion dysregulation framework
Cappadocia, M. C., Desrocher, M. E., Pepler, D. J., & Schroeder, J. H. (2009) · Clinical Psychology Review · doi:10.1016/j.cpr.2009.06.001 · Cited by 101 · see citing works
Autonomic characteristics of agoraphobia with panic attacks
Roth, W. T., Telch, M. J., Taylor, C. B., Sachitano, J. A., Gallen, C. C., Kopell, M. L., McClenahan, K. L., Agras, W. S., & Pfefferbaum, A. (1986) · Biological Psychiatry · doi:10.1016/0006-3223(86)90221-0 · Cited by 97 · see citing works
Methodological considerations in ambulatory skin conductance monitoring
Doberenz, S., Roth, W. T., Wollburg, E., Maslowski, N. I., & Kim, S. (2011) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2011.02.002 · Cited by 96 · see citing works
Habituation of the Skin Conductance Response to Strong Stimuli: A Twin Study
Lykken, D. T., Iacono, W. G., Haroian, K., Gue, M. M., & Bouchard, T. J. (1988) · Psychophysiology · doi:10.1111/j.1469-8986.1988.tb00949.x · Cited by 94 · see citing works
Somatic influences on subjective well-being and affective disorders: the convergence of thermosensory and central serotonergic systems
Raison, C. L., Hale, M. W., Williams, L. E., Wager, T. D., & Lowry, C. A. (2015) · Frontiers in Psychology · doi:10.3389/fpsyg.2014.01580 · Cited by 76 · see citing works
Memory and Emotions for the September 11, 2001, Terrorist Attacks in Patients With Alzheimer's Disease, Patients With Mild Cognitive Impairment, and Healthy Older Adults.
Budson, A. E., Simons, J. S., Sullivan, A. L., Beier, J. S., Solomon, P. R., Scinto, L. F. M., Daffner, K. R., & Schacter, D. L. (2004) · Neuropsychology · doi:10.1037/0894-4105.18.2.315 · Cited by 76 · see citing works
A method to elicit aggressive feelings and behaviour via provocation
Bond, A. J., & LADER, M. H. (1986) · Biological Psychology · doi:10.1016/0301-0511(86)90021-9 · Cited by 75 · see citing works
Nocturnal sweating and temperature in depression
Aver, D. H., Shah, S. H., Eder, D. N., & Wildschindtz, G. (1999) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1999.tb10864.x · Cited by 73 · see citing works
Depressed patients have atypical hemispace biases in the perception of emotional chimeric faces.
Jaeger, J., Borod, J. C., & Peselow, E. D. (1987) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.96.4.321 · Cited by 73 · see citing works
Detecting changes in facial temperature induced by a sudden auditory stimulus based on deep learning-assisted face tracking
Sonkusare, S., Ahmedt‐Aristizabal, D., Aburn, M. J., Nguyen, V. T., Pang, T., Frydman, S., Denman, S., Fookes, C., Breakspear, M. J., & Guo, C. C. (2019) · Scientific Reports · doi:10.1038/s41598-019-41172-7 · Cited by 67 · see citing works
The P300 ERP component: an index of cognitive dysfunction xin depression?
Sara, G. E., Gordon, E., Kraiuhin, C., Coyle, S., Howson, A., & Meares, R. A. (1994) · Journal of Affective Disorders · doi:10.1016/0165-0327(94)90124-4 · Cited by 65 · see citing works
Integrative physiology of depression and antidepressant drug action: Implications for serotonergic mechanisms of action and novel therapeutic strategies for treatment of depression
Hale, M. W., Raison, C. L., & Lowry, C. A. (2012) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2012.09.005 · Cited by 64 · see citing works
Reduced positive emotion and underarousal are uniquely associated with subclinical depression symptoms: Evidence from psychophysiology, self‐report, and symptom clusters
Benning, S. D., & Oumeziane, B. A. (2017) · Psychophysiology · doi:10.1111/psyp.12853 · Cited by 66 · see citing works
Biological studies of Dysthymia
Howland, R. H., & Thase, M. E. (1991) · Biological Psychiatry · doi:10.1016/0006-3223(91)90112-y · Cited by 62 · see citing works
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Markiewicz, R., Markiewicz-Gospodarek, A., & Dobrowolska, B. B. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192013428 · Cited by 59 · see citing works
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Iacono, W. G., Peloquin, L. J., Lykken, D. T., Haroian, K. P., Valentine, R. H., & Tuason, V. B. (1984) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.93.3.304 · Cited by 58 · see citing works
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Fráguas, R., Marci, C. D., D, M. F. M., Iosifescu, D. V., Bankier, B., Loh, R., & Dougherty, D. D. (2007) · Psychiatry Research · doi:10.1016/j.psychres.2006.08.008 · Cited by 57 · see citing works
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Stone, L. B., McCormack, C. C., & Bylsma, L. M. (2020) · Psychophysiology · doi:10.1111/psyp.13636 · Cited by 55 · see citing works
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Williams, K. M., Iacono, W. G., & Remick, R. A. (1985) · Biological Psychiatry · doi:10.1016/0006-3223(85)90075-7 · Cited by 51 · see citing works
Intensified emotion perception in depression: Differences in physiological arousal and subjective perceptions
Wenzler, S., Hagen, M., Tarvainen, M. P., Hilke, M., Ghirmai, N., Huthmacher, A.-C., Trettin, M., van Dick, R., Reif, A., & Oertel‐Knöchel, V. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.03.040 · Cited by 48 · see citing works
Facial expression of positive and negative emotions in patients with unipolar depression
Jaeger, J., Borod, J. C., & Peselow, E. D. (1986) · Journal of Affective Disorders · doi:10.1016/0165-0327(86)90058-3 · Cited by 44 · see citing works
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Zahn, T. P. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810120062010 · Cited by 43 · see citing works
Galvanic Skin Response in Mood Disorders: A Critical Review
Vahey, R., & Becerra, R. (2015) · Australasian Journal of Paramedicine · Cited by 42 · see citing works
Children’s sleep, skin conductance level and mental health
El‐Sheikh, M., & Arsiwalla, D. D. (2010) · Journal of Sleep Research · doi:10.1111/j.1365-2869.2010.00880.x · Cited by 40 · see citing works
Electrodermal activity in suicidal and nonsuicidal depressive patients and in matched healthy subjects
Thorell, L. (1987) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1987.tb05627.x · Cited by 36 · see citing works
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Thorell, L., Kjellman, B., & D'Elia, G. (1987) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1987.tb02940.x · Cited by 35 · see citing works
Objective physiological and behavioral measures for identifying and tracking depression state in clinically depressed patients
Sung, M., Carl, M., & Pentland, A. (2005) · Cited by 34 · see citing works
EEG and electrodermal activity in girls with Attention-Deficit/Hyperactivity Disorder.
Dupuy, F. E., Clarke, A., Barry, R. J., Selikowitz, M., & McCarthy, R. (2014) · Clinical Neurophysiology · doi:10.1016/j.clinph.2013.09.007 · Cited by 40 · see citing works
Autonomic Changes in Psychogenic Nonepileptic Seizures
Reinsberger, C., Sarkis, R. A., Papadelis, C. L., Doshi, C., Perez, D. L., Baslet, G. C., Loddenkemper, T., & Dworetzky, B. A. (2015) · Clinical EEG and Neuroscience · doi:10.1177/1550059414567739 · Cited by 31 · see citing works
Habituation and cortisol dysregulation in depression
Reus, V. I., Peeke, H. V. S., & Miner, C. (1985) · Biological Psychiatry · doi:10.1016/0006-3223(85)90196-9 · Cited by 31 · see citing works
A computationally informed distinction of interoception and exteroception
Toussaint, B., Heinzle, J., & Stephan, K. E. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105608 · Cited by 32 · see citing works
Concordance between anxiety and autonomic nervous system activity in subjects at genetic risk for affective disorder
Zahn, T. P., Nurnberger, J. I., Berrettini, W. H., & Robinson, T. N. (1991) · Psychiatry Research · doi:10.1016/0165-1781(91)90121-5 · Cited by 29 · see citing works
Evaluation of different methods used to measure malonyldialdehyde in human erythrocytes.
Srour, M. A., Bilto, Y. Y., & Juma, M. (2000) · PubMed · Cited by 29 · see citing works
Diagnostic utility of autonomic measures for major depressive disorders
Dawson, M. E., Schell, A. M., Braaten, J. R., & Catania, J. J. (1985) · Psychiatry Research · doi:10.1016/0165-1781(85)90063-0 · Cited by 29 · see citing works
Electrodermally differentiated subgroups of anxiety patients and controls. II: Relationships with auditory, somatosensory and pain thresholds, agoraphobic fear, depression and cerebral laterality
Kopp, M., & Gruzelier, J. H. (1989) · International Journal of Psychophysiology · doi:10.1016/0167-8760(89)90032-9 · Cited by 29 · see citing works
Reanalysis of SCOR and Anxiety Measures in the Israeli High-risk Study
Kugelmass, S., Faber, N., Frenkel, E., Ingraham, L. J., Nathan, M., Mirsky, A. F., & Ben‐Shakhar, G. (1995) · Schizophrenia Bulletin · doi:10.1093/schbul/21.2.205 · Cited by 28 · see citing works
Electrodermal activity in relation to diagnostic subgroups and symptoms of depressive patients
Thorell, L., Kjellman, B., & D'Elia, G. (1987) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1987.tb02941.x · Cited by 25 · see citing works
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Sano, A. (2016) · DSpace@MIT (Massachusetts Institute of Technology) · Cited by 20 · see citing works
Electrodermal activity in depressive patients in remission and in matched healthy subjects
Thorell, L., & D'Elia, G. (1988) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1988.tb06332.x · Cited by 18 · see citing works
Differing patterns of electrodermal and finger pulse responsivity in schizophrenia and depression
Bernstein, A. S., Schnur, D. B., Bernstein, P., Yeager, A., Wrable, J. A., & Smith, S. (1995) · Psychological Medicine · doi:10.1017/s0033291700028087 · Cited by 18 · see citing works
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Murck, H., LAUGHREN, T. P., Lamers, F., Picard, R. W., Walther, S., GOFF, D. C., & Sainati, S. M. (2015) · Europe PMC (PubMed Central) · doi:10.7892/boris.69085 · Cited by 17 · see citing works
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Lowry, C. A., Flux, M. C., & Raison, C. L. (2018) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.20180009 · Cited by 17 · see citing works
Psychophysiological evidence for cerebral laterality effects in a high- risk sample of students with subsyndromal bipolar depressive disorder
Lenhart, R. E., & Katkin, E. S. (1986) · American Journal of Psychiatry · doi:10.1176/ajp.143.5.602 · Cited by 17 · see citing works
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Pruneti, C. A., Fiduccia, A., & Guidotti, S. (2023) · Journal of Affective Disorders Reports · doi:10.1016/j.jadr.2023.100673 · Cited by 16 · see citing works
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Mestanikova, A., Ondrejka, I., Mestanik, M., Hrtánek, I., Šnircová, E., & Tonhajzerová, I. (2016) · Advances in experimental medicine and biology · doi:10.1007/5584_2016_40 · Cited by 16 · see citing works
Early maternal separation promotes alterations in the thermoregulatory profile of adult Wistar rats
Melo, C., Vizin, R. C. L., Silva, N. U., Ishikawa, D. T., Echeverry, M. B., Carrettiero, D. C., & Almeida, M. C. (2018) · Journal of Thermal Biology · doi:10.1016/j.jtherbio.2018.09.013 · Cited by 16 · see citing works
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Sponheim, S. R., Allen, J. J. B., & Iacono, W. G. (1995) · Series in psychopathology · doi:10.1007/978-1-4612-4234-5_8 · Cited by 16 · see citing works
Applications of Electrodermal Recording
Boucsein, W. (2011) · Springer eBooks · doi:10.1007/978-1-4614-1126-0_3 · Cited by 15 · see citing works
Predicting risk of suicide using resting state heart rate
Sikander, D., Arvaneh, M., Amico, F., Healy, G. F., Ward, T. E., Kearney, D., Mohedano, E., Fagan, J., Yek, J., Smeaton, A. F., et al. (2016) · Asia-Pacific Signal and Information Processing Association Annual Summit and Conference (APSIPA ASC) · doi:10.1109/apsipa.2016.7820833 · Cited by 14 · see citing works
Towards ecosystem for research and development of electrodermal activity applications
Jussila, J., Venho, N., Salonius, H., Moilanen, J., Liukkonen, J., & Rinnetmäki, M. (2018) · International Academic Mindtrek Conference (Mindtrek) · doi:10.1145/3275116.3275141 · Cited by 13 · see citing works
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Thorell, L., Kjellman, B., D'Elia, G., & Kågedal, B. (1988) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1988.tb06414.x · Cited by 11 · see citing works
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Dolu, N., Süer, C., Özesmi, Ç., Keleştimur, F., & Eşel, E. (1997) · Biological Psychiatry · doi:10.1016/s0006-3223(96)00551-3 · Cited by 10 · see citing works
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Motivational systems and autonomic functioning: Overlapping and differential contributions to anhedonic depression and anxious arousal
Sanders, W., & Abaied, J. L. (2015) · Motivation and Emotion · doi:10.1007/s11031-015-9470-5 · Cited by 6 · see citing works
Modulation of Physiological Responses as Indices of Attentional Bias in Dysphoria
Gantiva, C., Araujo, A., Aragão, N., & Hewitt, N. (2017) · International Journal of Mental Health and Addiction · doi:10.1007/s11469-017-9774-7 · Cited by 6 · see citing works
Physiologic Monitoring in Psychodynamic Psychotherapy Research
Marci, C. D., & Riess, H. (2008) · Humana Press eBooks · doi:10.1007/978-1-59745-444-5_14 · Cited by 5 · see citing works
Affective Disorders
Thase, M. E. (1987) · Springer eBooks · doi:10.1007/978-1-4684-5230-3_4 · Cited by 5 · see citing works
Psychophysiologische Differenzierung von Angst und Depression
Strian, F. (1986) · Springer eBooks · doi:10.1007/978-3-642-82895-9_14 · Cited by 4 · see citing works
Douleur chronique et activité électrodermale
Naveteur, J. (2008) · Douleur et Analgésie · doi:10.1007/s11724-008-0085-4 · Cited by 3 · see citing works
Experimental Models for Research in Stress and Behavior
Robert-McComb, J. J., Casey, S., Kim, Y., Hart, M. A., Norman, R., & Qian, X. (2015) · Journal of Behavioral and Brain Science · doi:10.4236/jbbs.2015.57030 · Cited by 3 · see citing works
Maternal depression during the perinatal period and its relationship with emotion regulation in young adulthood: An fMRI study in a prenatal birth cohort
Marečková, K., Trbusek, F., Mareček, R., Chládek, J., Koscova, Z., Plešinger, F., Andrýsková, L., Brázdil, M., & Nikolova, Y. S. (2025) · Psychological Medicine · doi:10.1017/s0033291725000042 · Cited by 2 · see citing works
The relation between electrodermal activity in sleep, negative activity affect, and stress in patients referred for nocturnal polysomnography
Lajos, L. E. (2002) · doi:10.31390/gradschool_dissertations.3902 · Cited by 2 · see citing works
Concepts and Dysfunctions of Emotion in Neuropsychiatric Research
Şen, Z. D., Čolić, L., Kasties, V., & Walter, M. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-981-32-9721-0_22 · Cited by 1 · see citing works
Associations of Continuous Electrodermal Activity with Job Burnout and Work EngagementPreprint
Salonius, H., Kytölä, P., Pakarinen, S., Mäkikangas, A., Liukkonen, V., & Mauno, S. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4726455 · Cited by 1 · see citing works
Repetitive negative thinking and the maintenance of social appearance anxiety : an experimental manipulation using psychophysiological and subjective measurement
Reilly, E. E. (2017) · doi:10.54014/c255-g0n6 · Cited by 1 · see citing works
The EEG activity of girls with attention-deficit/hyperactivity disorder
Dupuy, F. E. (2014) · Research Online (University of Wollongong)
Correlation Between Gut Microbiota and Depression
Naseribafrouei, A. (2013) · NORA - Norwegian Open Research Archives
Electrodermal hyporeactivity and suicide risk
Thorell, L. (2009) · doi:10.1093/med/9780198570059.003.0047
Phasic Electrodermal Activity in Schizophrenia: Skin Conductance Response in Unmedicated Schizophrenic Patients in Comparison to Normal Controls
Al‐Ghamdi, M. S. (2012) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3213z
Reflex vasodilation and sweating in response to passive whole body heating are blunted in women with major depressive disorder
Fisher, K. G., Leach, O. K., Greaney, J. L., Alexander, L. M., & Kenney, W. L. (2026) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00147.2026

Skin conductance. A potentially sensitive and specific marker for depression.
Ward, N. G., & Doerr, H. O. (1986) · PubMed · Cited by 35 · see citing works
Self-citation
Skin Conductance
Ward, N. G., & Doerr, H. O. (1986) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-198609000-00008 · Cited by 33 · see citing works
Self-citation
Diagnostic utility of autonomic measures for major depressive disorders
Dawson, M. E., Schell, A. M., Braaten, J. R., & Catania, J. J. (1985) · Psychiatry Research · doi:10.1016/0165-1781(85)90063-0 · Cited by 29 · see citing works
Skin conductance responses in Major Depressive Disorder (MDD) under mental arithmetic stress
Kim, A. Y., Jang, E. H., Choi, K. W., Jeon, H. J., Byun, S., Sim, J. Y., Choi, J. H., & Yu, H. Y. (2019) · PLoS ONE · doi:10.1371/journal.pone.0213140 · Cited by 40 · see citing works
Psychophysiological discriminants of depression at rest and in response to stress
Donat, D. C., & McCullough, J. P. (1983) · Journal of Clinical Psychology · doi:10.1002/1097-4679(198305)39:3 · Cited by 19 · see citing works

Authors: Ward, N. G., Doerr, H. O., & Storrie, M. C.
Corresponding author: Ward, Nicholas G.
Venue: Psychiatry Research
Publisher: Elsevier BV
Published: 1983-12
Volume: 10
Issue: 4
Pages: 295-302
ISSN: 0165-1781 (ISSN-L)
DOI: 10.1016/0165-1781(83)90076-8
OpenAlex: W1980616363
Cited by: 79
References: 27
Citations by year: 2026: 1 · 2025: 1 · 2024: 2 · 2023: 1 · 2022: 1 · 2021: 3 · 2020: 1 · 2019: 2 · 2018: 5 · 2017: 5 · 2016: 4 · 2015: 6 · 2014: 1 · 2013: 2 · 2012: 2
FWCI: 5.03
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Psychiatry Research (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Keywords: skin conductance, depression diagnosis, sensitivity and specificity, sex differences, antidepressants, depression biomarkers
MeSH terms: Adult, Depressive Disorder, Dexamethasone, Female, Galvanic Skin Response, Humans, Hydrocortisone, Male, Middle Aged, Psychological Tests

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Skin conductance: A potentially sensitive test for depression

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