Insulin and insulin-like growth factors in the CNS

Insulin receptors are widely distributed in the central nervous system of the rat

Havránková, J., Roth, J., & Brownstein, M. (1978) · Nature · doi:10.1038/272827a0 · Cited by 1,116 · see citing works

Cellular Localization of Somatomedin (Insulin-Like Growth Factor) Messenger RNA in the Human Fetus

Han, V. K. M., D’Ercole, A. J., & Lund, P. K. (1987) · Science · doi:10.1126/science.3563497 · Cited by 660 · see citing works

Somatomedin-C/insulin-like growth factor-I and insulin-like growth factor-II mRNAs in rat fetal and adult tissues.

Lund, P. K., Moats‐Staats, B. M., Hynes, M., Simmons, J. G., Jansen, M., D’Ercole, A. J., & Wyk, J. J. V. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)66903-0 · Cited by 532 · see citing works

Tissue Distribution of Insulin-Like Growth Factor I and II Messenger Ribonucleic Acid in the Adult Rat*

Murphy, L. J., Bell, G. I., & Friesen, H. G. (1987) · Endocrinology · doi:10.1210/endo-120-4-1279 · Cited by 418 · see citing works

Autoradiographic localization of insulin receptors in rat brain: Prominence in olfactory and limbic areas

Hill, J. M., Lesniak, M. A., Pert, C. B., & Roth, J. (1986) · Neuroscience · doi:10.1016/0306-4522(86)90082-5 · Cited by 413 · see citing works

Blood-brain barrier transcytosis of insulin in developing rabbits

Duffy, K. R., & Pardridge, W. M. (1987) · Brain Research · doi:10.1016/0006-8993(87)90236-8 · Cited by 358 · see citing works

Insulin In The Brain

Baskin, D. G., Figlewicz, D. P., Woods, S. C., Porte, D., & Dorsa, D. M. (1987) · Annual Review of Physiology · doi:10.1146/annurev.ph.49.030187.002003 · Cited by 344 · see citing works

Developmental regulation of insulin-like growth factor II mRNA in different rat tissues.

Brown, A. L., Graham, D. E., Nissley, S. P., Hill, D. J., Strain, A. J., & Rechler, M. M. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)69282-8 · Cited by 321 · see citing works

Receptor-Mediated Peptide Transport through the Blood-Brain Barrier*

Pardridge, W. M. (1986) · Endocrine Reviews · doi:10.1210/edrv-7-3-314 · Cited by 316 · see citing works

ADVANCES IN METABOLIC DISORDERS

Jordan, A. (1965) · Journal of Clinical Pathology · doi:10.1136/jcp.18.5.692-d · Cited by 296 · see citing works

Insulin in the Cerebrospinal Fluid

MARGOLIS, R. U., & ALTSZULER, N. (1967) · Nature · doi:10.1038/2151375a0 · Cited by 278 · see citing works

Insulin-like growth factors and insulin: comparative aspects

Froesch, E. R., & Zapf, J. (1985) · Diabetologia · doi:10.1007/bf00281982 · Cited by 263 · see citing works

Insulin binds to specific receptors and stimulates 2-deoxy-D-glucose uptake in cultured glial cells from rat brain.

Clarke, D. W., Boyd, F. T., Kappy, M. S., & Raizada, M. K. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)71260-3 · Cited by 261 · see citing works

Cerebrospinal Fluid Insulin Levels Increase During Intravenous Insulin Infusions in Man*

Wallum, B. J., Taborsky, G. J., Porte, D., Figlewicz, D. P., Jacobson, L., Beard, J. C., Ward, W. K., & Dorsa, D. M. (1987) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-64-1-190 · Cited by 254 · see citing works

Insulin-like growth factor I (IGF I) stimulates DNA synthesis in fetal rat brain cell cultures

Lenoir, D., & Honegger, P. (1983) · Developmental Brain Research · doi:10.1016/0165-3806(83)90177-3 · Cited by 231 · see citing works

Intraventricular insulin reduces food intake and body weight of lean but not obese zucker rats

Ikeda, H., West, D. B., Pustek, J. J., Figlewicz, D. P., Greenwood, M. R. C., Porte, D., & Woods, S. C. (1986) · Appetite · doi:10.1016/s0195-6663(86)80006-x · Cited by 230 · see citing works

Regional Concentrations of Insulin in the Rat Brain*

Baskin, D. G., Porte, D., GUEST, K., & Dorsa, D. M. (1983) · Endocrinology · doi:10.1210/endo-112-3-898 · Cited by 212 · see citing works

The Type II Insulin-Like Growth Factor (IGF) Receptor Has Low Affinity for IGF-I Analogs: Pleiotypic Actions of IGFs on Myoblasts Are Apparently Mediated by the Type I Receptor*

Dz, E., Falen, S. L., & Florini, J. R. (1987) · Endocrinology · doi:10.1210/endo-120-1-115 · Cited by 208 · see citing works

Characterization of Insulin-Like Growth Factor Receptors in Rat Anterior Pituitary, Hypothalamus, and Brain*

Goodyer, C. G., Stephano, L. D., Lai, W. H., Guyda, H. J., & Posner, B. I. (1984) · Endocrinology · doi:10.1210/endo-114-4-1187 · Cited by 197 · see citing works

Rat insulin-like growth factor II gene

Soares, M. B., Turken, A., Ishii, D. N., Mills, L., Episkopou, V., Cotter, S., Zeitlin, S. O., & Efstratiadis, A. (1986) · Journal of Molecular Biology · doi:10.1016/0022-2836(86)90025-2 · Cited by 194 · see citing works

Ontogenesis of somatomedin and insulin receptors in the human fetus.

Sara, V. R., Hall, K. E., Misaki, M., Fryklund, L., Christensen, N. J., & Wetterberg, L. (1983) · Journal of Clinical Investigation · doi:10.1172/jci110858 · Cited by 194 · see citing works

Insulin-like growth factor I receptors in neuronal and glial cells. Characterization and biological effects in primary culture.

Shemer, J., Raizada, M. K., Masters, B. A., Ota, A., & LeRoith, D. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47623-5 · Cited by 191 · see citing works

The Na,K-ATPase of nervous tissue

Stahl, W. L. (1986) · Neurochemistry International · doi:10.1016/0197-0186(86)90179-8 · Cited by 175 · see citing works

Binding and Internalization of Insulin and Insulin-Like Growth Factors by Isolated Brain Microvessels

Frank, H. J. L., Pardridge, W. M., Morris, W. L., Rosenfeld, R. G., & Choi, T. B. (1986) · Diabetes · doi:10.2337/diab.35.6.654 · Cited by 170 · see citing works

Localization of 125I-insulin binding sites in the rat hypothalamus by quantitative autoradiography

Woods, S. C., Porte, D., Dorsa, D. M., Figlewicz, D. P., & Baskin, D. G. (1986) · Neuroscience Letters · doi:10.1016/0304-3940(86)90430-1 · Cited by 168 · see citing works

Identification of Somatomedin/Insulin-Like Growth Factor Immunoreactive Cells in the Human Fetus

Han, V. K. M., Hill, D. J., Strain, A. J., Towle, A. C., Lauder, J. M., Underwood, L. E., & D’Ercole, A. J. (1987) · Pediatric Research · doi:10.1203/00006450-198709000-00001 · Cited by 164 · see citing works

Evidence for the presence of specific receptors for insulin-like growth factors 1 (IGF-1) and 2 (IGF-2) and insulin throughout the adult human brain

Saka, V. R., Hall, K. E., Holtz, H. V., HUMBEL, R. E., Sjören, B., & Wetterberg, L. (1982) · Neuroscience Letters · doi:10.1016/0304-3940(82)90089-1 · Cited by 164 · see citing works

Two types of receptor for insulin‐like growth factors in mammalian brain.

Gammeltoft, S., Haselbacher, G. K., HUMBEL, R. E., Fehlmann, M., & OBBERGHEN, E. V. (1985) · The EMBO Journal · doi:10.1002/j.1460-2075.1985.tb04097.x · Cited by 162 · see citing works

EVIDENCE FOR TWO SPECIES OF INSULIN-LIKE GROWTH FACTOR II (IGF II AND “BIG” IGF II) IN HUMAN SPINAL FLUID

Haselbacher, G. K., & HUMBEL, R. E. (1982) · Endocrinology · doi:10.1210/endo-110-5-1822 · Cited by 160 · see citing works

Periventricular hypothalamic cells in the rat brain contain insulin mRNA

Young, W. S. (1986) · Neuropeptides · doi:10.1016/0143-4179(86)90035-1 · Cited by 148 · see citing works

Genetically obese zucker rats have abnormally low brain insulin content

Baskin, D. G., Stein, L. J., Ikeda, H., Woods, S. C., Figlewicz, D. P., Porte, D., Greenwood, M. R. C., & Dorsa, D. M. (1985) · Life Sciences · doi:10.1016/0024-3205(85)90166-3 · Cited by 138 · see citing works

Characterization of a neuronal subtype of insulin-like growth factor I receptor.

Burgess, S. K., Jacobs, S., Cuatrecasas, P., & Sahyoun, N. E. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)75681-6 · Cited by 131 · see citing works

Immunocytochemical Detection of Insulin in Rat Hypothalamus and Its Possible Uptake from Cerebrospinal Fluid*

Baskin, D. G., Woods, S. C., West, D. B., van Houten, M., Posner, B. I., Dorsa, D. M., & Porte, D. (1983) · Endocrinology · doi:10.1210/endo-113-5-1818 · Cited by 122 · see citing works

Quantitative receptor autoradiography

HALL, M. D., & Davenport, A. P. (1987) · Nature · doi:10.1038/326649b0 · Cited by 114 · see citing works

Characterization of somatomedin/insulin-like growth factor receptors and correlation with biologic action in cultured neonatal rat astroglial cells

Han, V., Lauder, J., & D'Ercole, A. (1987) · Journal of Neuroscience · doi:10.1523/jneurosci.07-02-00501.1987 · Cited by 108 · see citing works

Quantitative Autoradiographic Evidence for Insulin Receptors in the Choroid Plexus of the Rat Brain

Baskin, D. G., Brewitt, B., Davidson, D. A., Paquette, T. L., Figlewicz, D. P., Lewellen, T. K., Graham, M. K., Woods, S. G., & Dorsa, D. M. (1986) · Diabetes · doi:10.2337/diab.35.2.246 · Cited by 104 · see citing works

Brain and Liver Insulin Binding Is Decreased in Zucker Rats Carrying the ’fa’ Gene*

Figlewicz, D. P., Dorsa, D. M., Stein, L. J., Baskin, D. G., Paquette, T. L., Greenwood, M. R. C., Woods, S. C., & Porte, D. (1985) · Endocrinology · doi:10.1210/endo-117-4-1537 · Cited by 91 · see citing works

The Failure of Rat Hypothalamic Tissues to Take up Labeled Insulin in Vivo or to Respond to Insulin in Vitro

Goodner, C. J., & Berrie, M. A. (1977) · Endocrinology · doi:10.1210/endo-101-2-605 · Cited by 83 · see citing works

Comparative measurements of glucose, beta-hydroxybutyrate, acetoacetate, and insulin in blood and cerebrospinal fluid during starvation

Owen, O. E., Reichard, G., Boden, G. H., & Shuman, C. R. (1974) · Metabolism · doi:10.1016/0026-0495(74)90098-5 · Cited by 79 · see citing works

IMMUNOREACTIVE INSULIN LEVELS ARE ELEVATED IN THE CEREBROSPINAL FLUID OF GENETICALLY OBESE ZUCKER RATS

Stein, L. J., Dorsa, D. M., Baskin, D. G., Figlewicz, D. P., Ikeda, H., Frarikmann, S. P., Greenwood, M. R. C., Porte, D., & Woods, S. C. (1983) · Endocrinology · doi:10.1210/endo-113-6-2299 · Cited by 75 · see citing works

Evaluation of rat insulin messenger RNA in pancreatic and extrapancreatic tissues

Giddings, S. J., Chirgwin, J. M., & Permutt, M. A. (1985) · Diabetologia · doi:10.1007/bf00283141 · Cited by 69 · see citing works

Identification of Binding Sites for an Insulin-like Growth Factor (IGF-1) in the Median Eminence of the Rat Brain by Quantitative Autoradiography

Bohannon, N. J. V., Figlewicz, D. P., Wilcox, B. J., Porte, D., & Baskin, D. G. (1986) · Endocrinology · doi:10.1210/endo-119-2-943 · Cited by 69 · see citing works

Insulin receptors in rat brain cortex. Kinetic evidence for a receptor subtype in the central nervous system

Gammeltoft, S., Staun‐Olsen, P., Ottesen, B., & Fahrenkrug, J. (1984) · Peptides · doi:10.1016/0196-9781(84)90120-7 · Cited by 58 · see citing works

An inexpensive microcomputer digital imaging system for densitometry: quantitative autoradiography of insulin receptors with 125I and LKB ultrofilm

Baskin, D. G., Davidson, D., Lewellen, T. K., & Graham, M. M. (1986) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(86)90044-0 · Cited by 51 · see citing works

Binding and internalization of insulin and insulin-like growth factors by isolated brain microvessels

Frank, H. J., Pardridge, W. M., Morris, W. L., et al. (1986) · Diabetes · doi:10.2337/diabetes.35.6.654 · Cited by 51 · see citing works

Evidence for the role of insulin-like growth factor II (IGF-II) in the control of food intake

Lauterio, T. J., Marson, L., Daughaday, W. H., & Baile, C. A. (1987) · Physiology & Behavior · doi:10.1016/0031-9384(87)90279-4 · Cited by 48 · see citing works

Polypeptide growth factors and the CNS

Herschman, H. R. (1986) · Trends in Neurosciences · doi:10.1016/0166-2236(86)90020-2 · Cited by 47 · see citing works

Mediation of Insulin-Like Growth Factor Actions by the Insulin Receptor in H-35 Rat Hepatoma Cells*

Krett, N. L., Heaton, J. H., & GELEHRTER, T. D. (1987) · Endocrinology · doi:10.1210/endo-120-1-401 · Cited by 45 · see citing works

Proinsulin‐like material in mouse foetal brain cell cultures

Birch, N. P., Christie, D. L., & Renwick, A. G. C. (1984) · FEBS Letters · doi:10.1016/0014-5793(84)80266-5 · Cited by 45 · see citing works

Evidence for a subtype of insulin-like growth factor I receptor in brain

Heidenreich, K. A., Freidenberg, G. R., Figlewicz, D. P., & Gilmore, P. R. (1986) · Regulatory Peptides · doi:10.1016/0167-0115(86)90160-6 · Cited by 43 · see citing works

The distribution of somatomedins in the nervous system of the cat and their release following neural stimulation

Sara, V. R., Uvnäs‐Moberg, K., Uvnäs, B., Hall, K. E., Wetterberg, L., POSLONCEC, B., & Goiny, M. (1982) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1982.tb07105.x · Cited by 43 · see citing works

CNS Regulation of Carbohydrate Metabolism

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Quantitative autoradiographic evidence for insulin receptors in the choroid plexus of the rat brain

Baskin, D. G., Brewitt, B., Davidson, D. A., et al. (1986) · Diabetes · doi:10.2337/diabetes.35.2.246 · Cited by 38 · see citing works

Partial Purification of a Hypothalamic Factor that Inhibits Gonadotropin-Releasing Hormone-Stimulated Luteinizing Hormone Release*

HWAN, J.-C., & Freeman, M. E. (1987) · Endocrinology · doi:10.1210/endo-120-2-483 · Cited by 30 · see citing works

Origin of Insulin-Receptive Nerve Terminals in Rat Median Eminence*

van Houten, M., Nance, D. M., Gauthier, S. G., & Posner, B. I. (1983) · Endocrinology · doi:10.1210/endo-113-4-1393 · Cited by 29 · see citing works

Central nervous system control of food intake

Schwartz, M. W., Woods, S. C., Porte, D., Seeley, R. J., & Baskin, D. G. (2000) · Nature · doi:10.1038/35007534 · Cited by 6,451 · see citing works

Signals That Regulate Food Intake and Energy Homeostasis

Woods, S. C., Seeley, R. J., Porte, D., & Schwartz, M. W. (1998) · Science · doi:10.1126/science.280.5368.1378 · Cited by 1,169 · see citing works

Insulin‐like growth factors I and II

HUMBEL, R. E. (1990) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1990.tb15595.x · Cited by 996 · see citing works

Brain insulin and insulin receptors in aging and sporadic Alzheimer’s disease

Frölich, L., Blum-Degen, D., Bernstein, H.-G., Engelsberger, S., Humrich, J., Laufer, S., Muschner, D., Thalheimer, A., Türk, A., Hoyer, S., et al. (1998) · Journal of Neural Transmission · doi:10.1007/s007020050068 · Cited by 748 · see citing works

Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: Implications for diagnostic and therapeutic strategies

Chen, Z., & Zhong, C. (2013) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2013.06.004 · Cited by 695 · see citing works

Integration of Metabolism and Intake Regulation: A Review Focusing on Periparturient Animals

Ingvartsen, K. L., & Andersen, J. B. (2000) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(00)75029-6 · Cited by 586 · see citing works

The hypothalamus and the control of energy homeostasis

Williams, G., Bing, C., Cai, X., Harrold, J. A., King, P., & Liu, X. H. (2001) · Physiology & Behavior · doi:10.1016/s0031-9384(01)00612-6 · Cited by 573 · see citing works

Inhibition of hypothalamic neuropeptide Y gene expression by insulin.

Schwartz, M. W., Sipols, A. J., Marks, J. L., Sanacora, G., White, J. D., Scheurink, A., Kahn, S. E., Baskin, D. G., Woods, S. C., & Figlewicz, D. P. (1992) · Endocrinology · doi:10.1210/endo.130.6.1597158 · Cited by 555 · see citing works

The role of neuronal growth factors in neurodegenerative disorders of the human brain

Connor, B. J., & Dragunow, M. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00004-6 · Cited by 534 · see citing works

Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and the insulin-like growth factors I and II

Knüsel, B., Michel, P. P., Schwaber, J. S., & Hefti, F. F. (1990) · Journal of Neuroscience · doi:10.1523/jneurosci.10-02-00558.1990 · Cited by 521 · see citing works

Role of insulin and insulin receptor in learning and memory

Zhao, W., & Alkon, D. L. (2001) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(01)00455-5 · Cited by 492 · see citing works

Peripheral Signals Conveying Metabolic Information to the Brain: Short-Term and Long-Term Regulation of Food Intake and Energy Homeostasis

Havel, P. J. (2001) · Experimental Biology and Medicine · doi:10.1177/153537020122601102 · Cited by 476 · see citing works

Insulin-like growth factor I increases brain growth and central nervous system myelination in tTransgenic mice

Carson, M. J., Behringer, R. R., Brinster, R. L., & McMorris, F. A. (1993) · Neuron · doi:10.1016/0896-6273(93)90173-o · Cited by 474 · see citing works

Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases

Hefti, F., Hartikka, J., & Knusel, B. (1989) · Neurobiology of Aging · doi:10.1016/0197-4580(89)90118-8 · Cited by 466 · see citing works

Localization of insulin receptor mRNA in rat brain by in situ hybridization

MARKS, J. L., PORTE, D., STAHL, W. L., & BASKIN, D. G. (1990) · Endocrinology · doi:10.1210/endo-127-6-3234 · Cited by 448 · see citing works

Elevated risk of type 2 diabetes for development of Alzheimer disease: A key role for oxidative stress in brain

Butterfield, D. A., Di Domenico, F., & Barone, E. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2014.06.010 · Cited by 402 · see citing works

Insulin receptors in the central nervous system: Localization, signalling mechanisms and functional aspects

UNGER, J., Livingston, J. H., & Moss, A. (1991) · Progress in Neurobiology · doi:10.1016/0301-0082(91)90015-s · Cited by 399 · see citing works

Insulin and leptin: dual adiposity signals to the brain for the regulation of food intake and body weight

Baskin, D. G., Lattemann, D. F., Seeley, R. J., Woods, S. C., Porte, D., & Schwartz, M. W. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01974-5 · Cited by 396 · see citing works

Leptin and the Central Nervous System Control of Glucose Metabolism

Morton, G. J., & Schwartz, M. W. (2011) · Physiological Reviews · doi:10.1152/physrev.00007.2010 · Cited by 338 · see citing works

Metabolic effects of obesity: A review

Singla, P. (2010) · World Journal of Diabetes · doi:10.4239/wjd.v1.i3.76 · Cited by 337 · see citing works

Insulin resistance and Parkinson’s disease: A new target for disease modification?

Athauda, D. S., & Foltynie, T. (2016) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.10.001 · Cited by 333 · see citing works

Model for the regulation of energy balance and adiposity by the central nervous system

Schwartz, M. W., Baskin, D. G., Kaiyala, K. J., & Woods, S. C. (1999) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.4.584 · Cited by 323 · see citing works

Increased Hypothalamic Content of Preproneuropeptide Y Messenger Ribonucleic Acid in Genetically Obese Zucker Rats and Its Regulation by Food Deprivation*

Sanacora, G., Kershaw, M., Finkelstein, J. A., & White, J. D. (1990) · Endocrinology · doi:10.1210/endo-127-2-730 · Cited by 309 · see citing works

Risk Factors for the Development of Obesity in Children Surviving Brain Tumors

Lustig, R. H., Post, S. R., Srivannaboon, K., Rose, S. R., Danish, R. K., Burghen, G. A., Xiong, X., Wu, S., & Merchant, T. E. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021180 · Cited by 305 · see citing works

Neuropeptides, food intake and body weight regulation: a hypothalamic focus

Hillebrand, J. J., de Wied, D., & Adan, R. A. H. (2002) · Peptides · doi:10.1016/s0196-9781(02)00269-3 · Cited by 286 · see citing works

Neurotrophic molecules

Snider, W. D., & Johnson, E. M. (1989) · Annals of Neurology · doi:10.1002/ana.410260402 · Cited by 273 · see citing works

Cognitive effects of insulin in the central nervous system

Park, C. R. (2001) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(01)00016-1 · Cited by 270 · see citing works

Insulin-like growth factor-1 ameliorates age-related behavioral deficits

Markowska, A. L., Mooney, M., & Sonntag, W. E. (1998) · Neuroscience · doi:10.1016/s0306-4522(98)00143-2 · Cited by 274 · see citing works

Energy Homeostasis, Obesity and Eating Disorders: Recent Advances in Endocrinology

Gale, S. M., Castracane, V. D., & Mantzoros, C. S. (2004) · Journal of Nutrition · doi:10.1093/jn/134.2.295 · Cited by 263 · see citing works

Estrogen and the developing mammalian brain

Beyer, C. (1999) · Anatomy and Embryology · doi:10.1007/s004290050236 · Cited by 263 · see citing works

IGF-I and IGF-II protect cultured hippocampal and septal neurons against calcium-mediated hypoglycemic damage

Cheng, B., & Mattson, M. P. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-04-01558.1992 · Cited by 254 · see citing works

The developing CNS: a scenario for the action of proinsulin, insulin and insulin-like growth factors

de Pablo, F., & de la Rosa, E. J. (1995) · Trends in Neurosciences · doi:10.1016/0166-2236(95)93892-2 · Cited by 238 · see citing works

Brain Insulin: Regulation, Mechanisms of Action and Functions

Gerozissis, K. (2003) · Cellular and Molecular Neurobiology · doi:10.1023/a:1022598900246 · Cited by 232 · see citing works

Selective, Physiological Transport of Insulin Across the Blood-Brain Barrier: Novel Demonstration by Species-Specific Radioimmunoassays

Banks, W. A., Jaspan, J. B., & Kastin, A. J. (1997) · Peptides · doi:10.1016/s0196-9781(97)00198-8 · Cited by 219 · see citing works

Insulin and insulin-like growth factor receptors in the nervous system

Adamo, M. L., Raizada, M. K., & LeRoith, D. (1989) · Molecular Neurobiology · doi:10.1007/bf02935589 · Cited by 212 · see citing works

Quantitative autoradiographic localization of [125I]insulin‐like growth factor I, [125I]insulin‐like growth factor II, and [125I]insulin receptor binding sites in developing and adult rat brain

Kar, S., Chabot, J., & Quirion, R. (1993) · The Journal of Comparative Neurology · doi:10.1002/cne.903330306 · Cited by 210 · see citing works

Molecular links between Alzheimer’s disease and diabetes mellitus

Yang, Y., & Song, W. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.07.009 · Cited by 201 · see citing works

Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid.

Schwartz, M. W., Sipols, A. J., Kahn, S. E., Lattemann, D. F., Taborsky, G. J., Bergman, R. N., Woods, S. C., & Porte, D. (1990) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1990.259.3.e378 · Cited by 191 · see citing works

Increased hypothalamic neuropeptide Y expression following food deprivation

White, J. D., & Kershaw, M. (1990) · Molecular and Cellular Neuroscience · doi:10.1016/1044-7431(90)90040-b · Cited by 189 · see citing works

Insulin-like Growth Factor-1 (IGF-1) Improves both Neurological Motor and Cognitive Outcome Following Experimental Brain Injury

Saatman, K. E., Contreras, P. C., Smith, D. H., Raghupathi, R., McDermott, K. L., Fernandez, S. C., Sanderson, K. L., Voddi, M., & McIntosh, T. K. (1997) · Experimental Neurology · doi:10.1006/exnr.1997.6629 · Cited by 185 · see citing works

Insulin-like growth factor-1 is a potent neuronal rescue agent after hypoxic-ischemic injury in fetal lambs.

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